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ONTOLOGY REPORT - ANNOTATIONS

Term:His-Purkinje system cell differentiation
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Accession:GO:0060932 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles.

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His-Purkinje system cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irx3 iroquois homeobox 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:6,810,678...6,813,186
Ensembl chrNW_004936475:6,810,666...6,813,192 		JBrowse link
atrioventricular bundle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irx3 iroquois homeobox 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:6,810,678...6,813,186
Ensembl chrNW_004936475:6,810,666...6,813,192 		JBrowse link
G Tbx3 T-box transcription factor 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18467625) Ensembl
MGI		 PMID:18467625 GO_REF:0000107 NCBI chrNW_004936558:7,230,361...7,243,651
Ensembl chrNW_004936558:7,230,668...7,244,361 		JBrowse link
G Tbx5 T-box transcription factor 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936558:7,408,229...7,454,897
Ensembl chrNW_004936558:7,408,222...7,454,901 		JBrowse link
Purkinje myocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx2-5 NK2 homeobox 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17250822) Ensembl
MGI		 PMID:17250822 GO_REF:0000107 NCBI chrNW_004936609:2,406,004...2,408,980
Ensembl chrNW_004936609:2,406,004...2,409,046 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15871
    developmental process 6321
      cellular developmental process 4251
        cell differentiation 4250
          cardiocyte differentiation 187
            cardiac muscle cell differentiation 152
              His-Purkinje system cell differentiation 4
                His-Purkinje system cell development 0
                His-Purkinje system cell fate commitment 0
                Purkinje myocyte differentiation 1
                atrioventricular bundle cell differentiation 3
Path 2
Term Annotations click to browse term
  biological_process 15871
    developmental process 6321
      anatomical structure development 5953
        multicellular organism development 4829
          system development 4203
            circulatory system development 1214
              heart development 694
                cardiac muscle tissue development 271
                  cardiac conduction system development 20
                    His-Purkinje system development 6
                      His-Purkinje system cell differentiation 4
                        His-Purkinje system cell development 0
                        His-Purkinje system cell fate commitment 0
                        Purkinje myocyte differentiation 1
                        atrioventricular bundle cell differentiation 3
paths to the root