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ONTOLOGY REPORT - ANNOTATIONS

Term:His-Purkinje system cell differentiation
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Accession:GO:0060932 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles.

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His-Purkinje system cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irx3 iroquois homeobox 3 involved_in ISO (MGI:6101691|PMID:26786475) BHF-UCL PMID:26786475 MGI:6101691 NCBI chrNW_004955433:11,944,890...11,948,372
Ensembl chrNW_004955433:11,944,890...11,948,369 		JBrowse link
atrioventricular bundle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irx3 iroquois homeobox 3 involved_in ISO (MGI:6101691|PMID:26786475) BHF-UCL PMID:26786475 MGI:6101691 NCBI chrNW_004955433:11,944,890...11,948,372
Ensembl chrNW_004955433:11,944,890...11,948,369 		JBrowse link
G Tbx3 T-box transcription factor 3 acts_upstream_of_or_within ISO (PMID:18467625) MGI PMID:18467625 NCBI chrNW_004955455:15,988,153...16,000,156
Ensembl chrNW_004955455:15,988,663...16,000,063 		JBrowse link
G Tbx5 T-box transcription factor 5 involved_in ISO (MGI:3051695|PMID:15289437) BHF-UCL PMID:15289437 MGI:3051695 NCBI chrNW_004955455:16,133,130...16,217,894
Ensembl chrNW_004955455:16,132,975...16,217,953 		JBrowse link
Purkinje myocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx2-5 NK2 homeobox 5 acts_upstream_of_or_within ISO (PMID:17250822) MGI PMID:17250822 NCBI chrNW_004955408:25,833,649...25,836,673
Ensembl chrNW_004955408:25,832,683...25,836,840 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12346
    developmental process 5853
      cellular developmental process 3877
        cell differentiation 3876
          cardiocyte differentiation 183
            cardiac muscle cell differentiation 149
              His-Purkinje system cell differentiation 4
                His-Purkinje system cell development 0
                His-Purkinje system cell fate commitment 0
                Purkinje myocyte differentiation 1
                atrioventricular bundle cell differentiation 3
Path 2
Term Annotations click to browse term
  biological_process 12346
    developmental process 5853
      anatomical structure development 5540
        multicellular organism development 4550
          system development 3953
            circulatory system development 1157
              heart development 664
                cardiac muscle tissue development 260
                  cardiac conduction system development 18
                    His-Purkinje system development 6
                      His-Purkinje system cell differentiation 4
                        His-Purkinje system cell development 0
                        His-Purkinje system cell fate commitment 0
                        Purkinje myocyte differentiation 1
                        atrioventricular bundle cell differentiation 3
paths to the root