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ONTOLOGY REPORT - ANNOTATIONS


Term:His-Purkinje system cell differentiation
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Accession:GO:0060932 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles.



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His-Purkinje system cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irx3 iroquois homeobox 3 involved_in ISO (MGI:6101691|PMID:26786475) RGD PMID:26786475 MGI:6101691 NCBI chr19:15,211,882...15,215,323
Ensembl chr19:15,211,878...15,215,317
JBrowse link
atrioventricular bundle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irx3 iroquois homeobox 3 involved_in ISO (MGI:6101691|PMID:26786475) RGD PMID:26786475 MGI:6101691 NCBI chr19:15,211,882...15,215,323
Ensembl chr19:15,211,878...15,215,317
JBrowse link
G Tbx3 T-box transcription factor 3 acts_upstream_of_or_within ISO MGI:3710254 (MGI:3847383|PMID:18467625) RGD PMID:18467625 MGI:3847383 NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708
JBrowse link
G Tbx5 T-box transcription factor 5 involved_in IEA
ISO
GO_REF:0000107
(MGI:3051695|PMID:15289437)
Ensembl
RGD
PMID:15289437 GO_REF:0000107 MGI:3051695 NCBI chr12:36,686,344...36,739,253
Ensembl chr12:36,688,014...36,734,885
JBrowse link
Purkinje myocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx2-5 NK2 homeobox 5 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857618 (MGI:3785685|PMID:17250822)
Ensembl
RGD
PMID:17250822 GO_REF:0000107 MGI:3785685 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20091
    developmental process 7027
      cellular developmental process 4656
        cell differentiation 4633
          cardiocyte differentiation 202
            cardiac muscle cell differentiation 162
              His-Purkinje system cell differentiation 4
                His-Purkinje system cell development 0
                His-Purkinje system cell fate commitment 0
                Purkinje myocyte differentiation 1
                atrioventricular bundle cell differentiation 3
Path 2
Term Annotations click to browse term
  biological_process 20091
    developmental process 7027
      anatomical structure development 6464
        multicellular organism development 5238
          system development 4496
            circulatory system development 1334
              heart development 720
                cardiac muscle tissue development 280
                  cardiac conduction system development 20
                    His-Purkinje system development 6
                      His-Purkinje system cell differentiation 4
                        His-Purkinje system cell development 0
                        His-Purkinje system cell fate commitment 0
                        Purkinje myocyte differentiation 1
                        atrioventricular bundle cell differentiation 3
paths to the root