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ONTOLOGY REPORT - ANNOTATIONS


Term:cardiac muscle cell fate commitment
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Accession:GO:0060923 term browser browse the term
Definition:The commitment of cells to specific cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.
Synonyms:exact_synonym: cardiomyocyte cell fate commitment;   heart muscle cell fate commitment


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cardiac muscle cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in ISO
IEA
(PMID:19506109)
GO_REF:0000107
RGD
Ensembl
PMID:19506109 GO_REF:0000107 NCBI chr 3:44,432,476...44,539,680
Ensembl chr 3:44,432,471...44,522,930
JBrowse link
G Tbx3 T-box transcription factor 3 acts_upstream_of_or_within ISO MGI:3710254 (MGI:3847383|PMID:18467625) RGD PMID:18467625 MGI:3847383 NCBI chr12:42,479,518...42,494,588
Ensembl chr12:42,480,560...42,492,526
JBrowse link
G Wnt3a Wnt family member 3A acts_upstream_of_or_within ISO MGI:2143322 (MGI:5295932|PMID:21554246) RGD PMID:21554246 MGI:5295932 NCBI chr10:45,598,898...45,643,151
Ensembl chr10:45,598,912...45,638,035
JBrowse link
G Wt1 WT1 transcription factor involved_in ISO (MGI:5285454|PMID:21654746) RGD PMID:21654746 MGI:5285454 NCBI chr 3:95,133,221...95,180,574
Ensembl chr 3:95,133,713...95,180,564
JBrowse link
atrioventricular node cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx2-5 NK2 homeobox 5 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3042511 (MGI:3040116|PMID:15109497)
Ensembl
RGD
PMID:15109497 GO_REF:0000107 MGI:3040116 NCBI chr10:16,635,989...16,638,758
Ensembl chr10:16,635,989...16,638,764
JBrowse link
G Tbx5 T-box transcription factor 5 involved_in IEA
ISO
GO_REF:0000107
(MGI:3051695|PMID:15289437)
Ensembl
RGD
PMID:15289437 GO_REF:0000107 MGI:3051695 NCBI chr12:42,059,688...42,148,226
Ensembl chr12:42,097,626...42,148,146
JBrowse link
canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a Wnt family member 3A involved_in ISO (PMID:20559569) RGD PMID:20559569 NCBI chr10:45,598,898...45,643,151
Ensembl chr10:45,598,912...45,638,035
JBrowse link
G Wnt8a Wnt family member 8A involved_in ISO (PMID:20559569) RGD PMID:20559569 NCBI chr18:27,331,236...27,336,829
Ensembl chr18:27,331,236...27,336,829
JBrowse link
negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (PMID:20559569) RGD PMID:20559569 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607
Ensembl chr 1:248,895,738...248,898,607
JBrowse link
positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rbpj recombination signal binding protein for immunoglobulin kappa J region acts_upstream_of_or_within ISO MGI:3583755 (MGI:5432296|PMID:22711842) RGD PMID:22711842 MGI:5432296 NCBI chr14:59,657,738...59,865,427
Ensembl chr14:59,658,935...59,735,450
JBrowse link
sinoatrial node cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tbx18 T-box transcription factor 18 involved_in ISO (PMID:23242162) RGD PMID:23242162 NCBI chr 8:95,359,354...95,387,363
Ensembl chr 8:95,359,354...95,387,363
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    cellular process 18344
      cellular developmental process 4470
        cell fate commitment 281
          cardiac cell fate commitment 15
            cardiac muscle cell fate commitment 10
              atrial cardiac muscle cell fate commitment 0
              canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment + 4
              cardiac muscle cell fate determination 0
              cardiac pacemaker cell fate commitment + 3
              ventricular cardiac muscle cell fate commitment 0
Path 2
Term Annotations click to browse term
  biological_process 19491
    developmental process 6765
      anatomical structure development 6191
        multicellular organism development 5628
          system development 5300
            circulatory system development 1232
              heart development 695
                cardiac muscle tissue development 260
                  cardiac muscle cell differentiation 150
                    cardiac muscle cell fate commitment 10
                      atrial cardiac muscle cell fate commitment 0
                      canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment + 4
                      cardiac muscle cell fate determination 0
                      cardiac pacemaker cell fate commitment + 3
                      ventricular cardiac muscle cell fate commitment 0
paths to the root