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ONTOLOGY REPORT - ANNOTATIONS

Term:cardiac pacemaker cell differentiation
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Accession:GO:0060920 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.
Synonyms:broad_synonym: pacemaker cell differentiation


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cardiac pacemaker cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNJ8 potassium inwardly rectifying channel subfamily J member 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:29666184) Ensembl
MGI		 PMID:29666184 GO_REF:0000107 NCBI chr27:25,368,565...25,375,754
Ensembl chr27:25,368,810...25,375,009 		JBrowse link
G SHOX2 SHOX homeobox 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:51,484,696...51,492,586
Ensembl chr23:51,484,421...51,492,566 		JBrowse link
atrioventricular node cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMPR1A bone morphogenetic protein receptor type 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:34,499,898...34,582,481
Ensembl chr 4:34,517,492...34,578,923 		JBrowse link
G MAML1 mastermind like transcriptional coactivator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:1,915,622...1,927,598
Ensembl chr11:1,918,133...1,963,836 		JBrowse link
G NKX2-5 NK2 homeobox 5 acts_upstream_of_or_within ISO (PMID:19546853) MGI PMID:19546853 NCBI chr 4:39,240,755...39,254,585
Ensembl chr 4:39,244,286...39,247,592 		JBrowse link
G TBX5 T-box transcription factor 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:11,462,541...11,549,699
Ensembl chr26:11,463,653...11,506,446 		JBrowse link
atrioventricular node cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNJ8 potassium inwardly rectifying channel subfamily J member 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:29666184) Ensembl
MGI		 PMID:29666184 GO_REF:0000107 NCBI chr27:25,368,565...25,375,754
Ensembl chr27:25,368,810...25,375,009 		JBrowse link
atrioventricular node cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NKX2-5 NK2 homeobox 5 acts_upstream_of_or_within ISO (PMID:15109497) MGI PMID:15109497 NCBI chr 4:39,240,755...39,254,585
Ensembl chr 4:39,244,286...39,247,592 		JBrowse link
G TBX5 T-box transcription factor 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:11,462,541...11,549,699
Ensembl chr26:11,463,653...11,506,446 		JBrowse link
sinoatrial node cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BVES blood vessel epicardial substance involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22354168) Ensembl
MGI		 PMID:22354168 GO_REF:0000107 NCBI chr12:62,542,274...62,581,110
Ensembl chr12:62,545,666...62,579,548 		JBrowse link
G ISL1 ISL LIM homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:63,638,009...63,648,492
Ensembl chr 4:63,637,443...63,648,183 		JBrowse link
G POPDC2 popeye domain containing 2 acts_upstream_of_or_within ISO (PMID:22354168) MGI PMID:22354168 NCBI chr33:23,275,666...23,295,413
Ensembl chr33:23,276,455...23,295,088 		JBrowse link
G SHOX2 SHOX homeobox 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:51,484,696...51,492,586
Ensembl chr23:51,484,421...51,492,566 		JBrowse link
G TBX18 T-box transcription factor 18 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:44,901,076...44,929,730
Ensembl chr12:44,873,119...44,929,205 		JBrowse link
G TBX3 T-box transcription factor 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19096026) Ensembl
MGI		 PMID:19096026 GO_REF:0000107 NCBI chr26:11,694,885...11,709,594
Ensembl chr26:11,696,565...11,708,918 		JBrowse link
sinoatrial node cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MESP1 mesoderm posterior bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:52,738,333...52,739,962
Ensembl chr 3:52,738,366...52,739,755 		JBrowse link
sinoatrial node cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TBX18 T-box transcription factor 18 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:44,901,076...44,929,730
Ensembl chr12:44,873,119...44,929,205 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17917
    cellular process 16926
      cellular developmental process 4594
        cell differentiation 4593
          cardiocyte differentiation 206
            cardiac muscle cell differentiation 165
              cardiac pacemaker cell differentiation 12
                atrioventricular node cell differentiation + 5
                cardiac pacemaker cell development + 10
                cardiac pacemaker cell fate commitment + 3
                sinoatrial node cell differentiation + 7
Path 2
Term Annotations click to browse term
  biological_process 17917
    developmental process 6831
      anatomical structure development 6414
        multicellular organism development 5174
          system development 4502
            circulatory system development 1359
              heart development 737
                cardiac muscle tissue development 292
                  cardiac muscle cell differentiation 165
                    cardiac pacemaker cell differentiation 12
                      atrioventricular node cell differentiation + 5
                      cardiac pacemaker cell development + 10
                      cardiac pacemaker cell fate commitment + 3
                      sinoatrial node cell differentiation + 7
paths to the root