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ONTOLOGY REPORT - ANNOTATIONS


Term:cardiac pacemaker cell differentiation
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Accession:GO:0060920 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.
Synonyms:broad_synonym: pacemaker cell differentiation


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cardiac pacemaker cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Shox2 short stature homeobox 2 involved_in ISO (MGI:3836832|PMID:19166829) RGD PMID:19166829 MGI:3836832 NCBI chr 2:164,118,175...164,126,783
Ensembl chr 2:164,118,191...164,126,783
JBrowse link
atrioventricular node cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (MGI:3822612|PMID:17998461) RGD PMID:17998461 MGI:3822612 NCBI chr16:10,758,278...10,852,170
Ensembl chr16:10,758,527...10,802,512
JBrowse link
G Maml1 mastermind-like transcriptional coactivator 1 involved_in ISO (MGI:5000164|PMID:21266778) RGD PMID:21266778 MGI:5000164 NCBI chr10:35,765,196...35,801,375
Ensembl chr10:35,765,719...35,800,120
JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3042511 (MGI:4355491|PMID:19546853)
Ensembl
RGD
PMID:19546853 GO_REF:0000107 MGI:4355491 NCBI chr10:16,635,989...16,638,758
Ensembl chr10:16,635,989...16,638,764
JBrowse link
G Tbx5 T-box transcription factor 5 involved_in IEA
ISO
GO_REF:0000107
(MGI:3051695|PMID:15289437)
Ensembl
RGD
PMID:15289437 GO_REF:0000107 MGI:3051695 NCBI chr12:42,059,688...42,148,226
Ensembl chr12:42,097,626...42,148,146
JBrowse link
atrioventricular node cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx2-5 NK2 homeobox 5 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3042511 (MGI:3040116|PMID:15109497)
Ensembl
RGD
PMID:15109497 GO_REF:0000107 MGI:3040116 NCBI chr10:16,635,989...16,638,758
Ensembl chr10:16,635,989...16,638,764
JBrowse link
G Tbx5 T-box transcription factor 5 involved_in IEA
ISO
GO_REF:0000107
(MGI:3051695|PMID:15289437)
Ensembl
RGD
PMID:15289437 GO_REF:0000107 MGI:3051695 NCBI chr12:42,059,688...42,148,226
Ensembl chr12:42,097,626...42,148,146
JBrowse link
sinoatrial node cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bves blood vessel epicardial substance acts_upstream_of_or_within ISO MGI:2385915 (MGI:5424322|PMID:22354168) RGD PMID:22354168 MGI:5424322 NCBI chr20:50,439,885...50,474,678
Ensembl chr20:50,439,883...50,474,678
JBrowse link
G Isl1 ISL LIM homeobox 1 involved_in ISO (MGI:5688210|PMID:26193633) RGD PMID:26193633 MGI:5688210 NCBI chr 2:48,488,911...48,501,217
Ensembl chr 2:48,487,736...48,501,436
JBrowse link
G Popdc2 popeye domain containing 2 acts_upstream_of_or_within ISO MGI:3773727 (MGI:5424322|PMID:22354168) RGD PMID:22354168 MGI:5424322 NCBI chr11:64,915,041...64,954,704
Ensembl chr11:64,936,692...64,952,687
JBrowse link
G Shox2 short stature homeobox 2 involved_in ISO (MGI:5285465|PMID:21640717) RGD PMID:21640717 MGI:5285465 NCBI chr 2:164,118,175...164,126,783
Ensembl chr 2:164,118,191...164,126,783
JBrowse link
G Tbx18 T-box transcription factor 18 involved_in ISO (PMID:23242162) RGD PMID:23242162 NCBI chr 8:95,359,354...95,387,363
Ensembl chr 8:95,359,354...95,387,363
JBrowse link
G Tbx3 T-box transcription factor 3 involved_in
acts_upstream_of_or_within
ISO (PMID:22130515)
MGI:3710254 (MGI:4366226|PMID:19096026)
RGD PMID:19096026 PMID:22130515 MGI:4366226 NCBI chr12:42,479,518...42,494,588
Ensembl chr12:42,480,560...42,492,526
JBrowse link
sinoatrial node cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in ISO (PMID:18297060) RGD PMID:18297060 NCBI chr 1:141,532,390...141,533,908
Ensembl chr 1:141,532,390...141,533,908
JBrowse link
sinoatrial node cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tbx18 T-box transcription factor 18 involved_in ISO (PMID:23242162) RGD PMID:23242162 NCBI chr 8:95,359,354...95,387,363
Ensembl chr 8:95,359,354...95,387,363
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    developmental process 6766
      cellular developmental process 4470
        cell differentiation 4375
          cardiocyte differentiation 185
            cardiac muscle cell differentiation 150
              cardiac pacemaker cell differentiation 11
                atrioventricular node cell differentiation + 4
                cardiac pacemaker cell development + 10
                cardiac pacemaker cell fate commitment + 3
                sinoatrial node cell differentiation + 7
Path 2
Term Annotations click to browse term
  biological_process 19491
    developmental process 6766
      anatomical structure development 6192
        multicellular organism development 5629
          system development 5301
            animal organ development 4060
              heart development 695
                cardiac muscle tissue development 260
                  cardiac muscle cell differentiation 150
                    cardiac pacemaker cell differentiation 11
                      atrioventricular node cell differentiation + 4
                      cardiac pacemaker cell development + 10
                      cardiac pacemaker cell fate commitment + 3
                      sinoatrial node cell differentiation + 7
paths to the root