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ONTOLOGY REPORT - ANNOTATIONS


Term:cardiac pacemaker cell differentiation
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Accession:GO:0060920 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.
Synonyms:broad_synonym: pacemaker cell differentiation



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cardiac pacemaker cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Shox2 short stature homeobox 2 involved_in ISO (MGI:3836832|PMID:19166829) RGD PMID:19166829 MGI:3836832 NCBI chr 2:151,217,049...151,227,180
Ensembl chr 2:151,217,552...151,227,143
JBrowse link
atrioventricular node cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (MGI:3822612|PMID:17998461) RGD PMID:17998461 MGI:3822612 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616
JBrowse link
G Maml1 mastermind-like transcriptional coactivator 1 involved_in ISO (MGI:5000164|PMID:21266778) RGD PMID:21266778 MGI:5000164 NCBI chr10:34,588,639...34,624,298
Ensembl chr10:34,588,646...34,623,338
JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3042511 (MGI:4355491|PMID:19546853)
Ensembl
RGD
PMID:19546853 GO_REF:0000107 MGI:4355491 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934
JBrowse link
G Tbx5 T-box transcription factor 5 involved_in IEA
ISO
GO_REF:0000107
(MGI:3051695|PMID:15289437)
Ensembl
RGD
PMID:15289437 GO_REF:0000107 MGI:3051695 NCBI chr12:36,686,344...36,739,253
Ensembl chr12:36,688,014...36,734,885
JBrowse link
atrioventricular node cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx2-5 NK2 homeobox 5 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3042511 (MGI:3040116|PMID:15109497)
Ensembl
RGD
PMID:15109497 GO_REF:0000107 MGI:3040116 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934
JBrowse link
G Tbx5 T-box transcription factor 5 involved_in IEA
ISO
GO_REF:0000107
(MGI:3051695|PMID:15289437)
Ensembl
RGD
PMID:15289437 GO_REF:0000107 MGI:3051695 NCBI chr12:36,686,344...36,739,253
Ensembl chr12:36,688,014...36,734,885
JBrowse link
sinoatrial node cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bves blood vessel epicardial substance acts_upstream_of_or_within ISO MGI:2385915 (MGI:5424322|PMID:22354168) RGD PMID:22354168 MGI:5424322 NCBI chr20:48,819,241...48,860,282
Ensembl chr20:48,822,308...48,857,472
JBrowse link
G Isl1 ISL LIM homeobox 1 involved_in ISO (MGI:5688210|PMID:26193633) RGD PMID:26193633 MGI:5688210 NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584
JBrowse link
G Popdc2 popeye domain containing 2 acts_upstream_of_or_within ISO MGI:3773727 (MGI:5424322|PMID:22354168) RGD PMID:22354168 MGI:5424322 NCBI chr11:62,351,843...62,398,688
Ensembl chr11:62,374,759...62,390,756
JBrowse link
G Shox2 short stature homeobox 2 involved_in ISO
IEA
(MGI:5285465|PMID:21640717)
GO_REF:0000107
RGD
Ensembl
PMID:21640717 GO_REF:0000107 MGI:5285465 NCBI chr 2:151,217,049...151,227,180
Ensembl chr 2:151,217,552...151,227,143
JBrowse link
G Tbx18 T-box transcription factor 18 involved_in ISO (PMID:23242162) RGD PMID:23242162 NCBI chr 8:88,652,054...88,680,081
Ensembl chr 8:88,652,054...88,680,058
JBrowse link
G Tbx3 T-box transcription factor 3 involved_in
acts_upstream_of_or_within
ISO (PMID:22130515)
MGI:3710254 (MGI:4366226|PMID:19096026)
RGD PMID:19096026 PMID:22130515 MGI:4366226 NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708
JBrowse link
sinoatrial node cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in ISO (PMID:18297060) RGD PMID:18297060 NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875
JBrowse link
sinoatrial node cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tbx18 T-box transcription factor 18 involved_in ISO (PMID:23242162) RGD PMID:23242162 NCBI chr 8:88,652,054...88,680,081
Ensembl chr 8:88,652,054...88,680,058
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19876
    cellular process 18552
      cellular developmental process 4663
        cell differentiation 4639
          cardiocyte differentiation 203
            cardiac muscle cell differentiation 163
              cardiac pacemaker cell differentiation 11
                atrioventricular node cell differentiation + 4
                cardiac pacemaker cell development + 10
                cardiac pacemaker cell fate commitment + 3
                sinoatrial node cell differentiation + 7
Path 2
Term Annotations click to browse term
  biological_process 19876
    developmental process 7031
      anatomical structure development 6466
        multicellular organism development 5236
          system development 4498
            circulatory system development 1334
              heart development 724
                cardiac muscle tissue development 280
                  cardiac muscle cell differentiation 163
                    cardiac pacemaker cell differentiation 11
                      atrioventricular node cell differentiation + 4
                      cardiac pacemaker cell development + 10
                      cardiac pacemaker cell fate commitment + 3
                      sinoatrial node cell differentiation + 7
paths to the root