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ONTOLOGY REPORT - ANNOTATIONS


Term:cardiac cell fate commitment
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Accession:GO:0060911 term browser browse the term
Definition:The commitment of cells to specific cardiac cell fates and their capacity to differentiate into cardiac cells. Cardiac cells are cells that comprise the organ which pumps blood through the circulatory system.
Synonyms:exact_synonym: cardiocyte cell fate commitment



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atrioventricular node cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx2-5 NK2 homeobox 5 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3042511 (MGI:3040116|PMID:15109497)
Ensembl
RGD
PMID:15109497 GO_REF:0000107 MGI:3040116 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934
JBrowse link
G Tbx5 T-box transcription factor 5 involved_in IEA
ISO
GO_REF:0000107
(MGI:3051695|PMID:15289437)
Ensembl
RGD
PMID:15289437 GO_REF:0000107 MGI:3051695 NCBI chr12:36,686,344...36,739,253
Ensembl chr12:36,688,014...36,734,885
JBrowse link
canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a Wnt family member 3A involved_in ISO (PMID:20559569) RGD PMID:20559569 NCBI chr10:44,034,174...44,078,463
Ensembl chr10:44,034,194...44,078,324
JBrowse link
G Wnt8a Wnt family member 8A involved_in ISO (PMID:20559569) RGD PMID:20559569 NCBI chr18:26,137,690...26,143,283
Ensembl chr18:26,137,690...26,143,283
JBrowse link
cardiac cell fate determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Isl1 ISL LIM homeobox 1 involved_in
acts_upstream_of_or_within
ISO (PMID:19571884)
(MGI:4438134|PMID:19620969)
RGD PMID:19571884 PMID:19620969 MGI:4438134 NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584
JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in ISO (MGI:4441249|PMID:18593560) RGD PMID:18593560 MGI:4441249 NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875
JBrowse link
G Pou5f1 POU class 5 homeobox 1 involved_in ISO (PMID:19736317) RGD PMID:19736317 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
JBrowse link
G Sox17 SRY-box transcription factor 17 involved_in ISO (PMID:19736317) RGD PMID:19736317 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228
JBrowse link
cardiac cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tenm4 teneurin transmembrane protein 4 acts_upstream_of_or_within ISO MGI:3655239 (MGI:5429684|PMID:17350578) RGD PMID:17350578 MGI:5429684 NCBI chr 1:149,895,097...151,263,315
Ensembl chr 1:150,780,381...151,259,144
JBrowse link
cardiac muscle cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in ISO
IEA
(PMID:19506109)
GO_REF:0000107
RGD
Ensembl
PMID:19506109 GO_REF:0000107 NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241
JBrowse link
G Tbx3 T-box transcription factor 3 acts_upstream_of_or_within ISO MGI:3710254 (MGI:3847383|PMID:18467625) RGD PMID:18467625 MGI:3847383 NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708
JBrowse link
G Wnt3a Wnt family member 3A acts_upstream_of_or_within ISO MGI:2143322 (MGI:5295932|PMID:21554246) RGD PMID:21554246 MGI:5295932 NCBI chr10:44,034,174...44,078,463
Ensembl chr10:44,034,194...44,078,324
JBrowse link
G Wt1 WT1 transcription factor involved_in ISO (MGI:5285454|PMID:21654746) RGD PMID:21654746 MGI:5285454 NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643
JBrowse link
endocardial cushion cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in ISO
IEA
(PMID:19506109)
GO_REF:0000107
RGD
Ensembl
PMID:19506109 GO_REF:0000107 NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241
JBrowse link
negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (PMID:20559569) RGD PMID:20559569 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
JBrowse link
negative regulation of heart induction by canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a Wnt family member 3A involved_in ISO (PMID:19736317) RGD PMID:19736317 NCBI chr10:44,034,174...44,078,463
Ensembl chr10:44,034,194...44,078,324
JBrowse link
positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rbpj recombination signal binding protein for immunoglobulin kappa J region acts_upstream_of_or_within ISO MGI:3583755 (MGI:5432296|PMID:22711842) RGD PMID:22711842 MGI:5432296 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353
JBrowse link
regulation of cardiac cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sox17 SRY-box transcription factor 17 involved_in ISO (MGI:3703823|PMID:17360443) RGD PMID:17360443 MGI:3703823 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228
JBrowse link
sinoatrial node cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tbx18 T-box transcription factor 18 involved_in ISO (PMID:23242162) RGD PMID:23242162 NCBI chr 8:88,652,054...88,680,081
Ensembl chr 8:88,652,054...88,680,058
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19504
    cellular process 18357
      cellular developmental process 4482
        cell fate commitment 283
          cardiac cell fate commitment 15
            His-Purkinje system cell fate commitment 0
            cardiac cell fate determination + 4
            cardiac cell fate specification + 3
            cardiac fibroblast cell fate commitment + 0
            cardiac glial cell fate commitment + 0
            cardiac muscle cell fate commitment + 10
            cardiac neuron fate commitment 0
            cardiac vascular smooth muscle cell fate commitment + 0
            cardioblast cell fate commitment + 1
            dorsal vessel aortic cell fate commitment 0
            dorsal vessel heart proper cell fate commitment 0
            endocardial cell fate commitment + 1
Path 2
Term Annotations click to browse term
  biological_process 19504
    developmental process 6778
      anatomical structure development 6203
        multicellular organism development 5642
          system development 5310
            animal organ development 4069
              heart development 697
                cardiocyte differentiation 187
                  cardiac cell fate commitment 15
                    His-Purkinje system cell fate commitment 0
                    cardiac cell fate determination + 4
                    cardiac cell fate specification + 3
                    cardiac fibroblast cell fate commitment + 0
                    cardiac glial cell fate commitment + 0
                    cardiac muscle cell fate commitment + 10
                    cardiac neuron fate commitment 0
                    cardiac vascular smooth muscle cell fate commitment + 0
                    cardioblast cell fate commitment + 1
                    dorsal vessel aortic cell fate commitment 0
                    dorsal vessel heart proper cell fate commitment 0
                    endocardial cell fate commitment + 1
paths to the root