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ONTOLOGY REPORT - ANNOTATIONS

Term:blood vessel endothelial cell differentiation
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Accession:GO:0060837 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels.


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blood vessel endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccm2 CCM2 scaffold protein acts_upstream_of_or_within ISO
IEA		 MGI:3512761 (PMID:19151727)
GO_REF:0000107		 RGD
Ensembl		 PMID:19151727 GO_REF:0000107 NCBI chr14:85,632,338...85,678,016
Ensembl chr14:81,418,236...81,464,116 		JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 acts_upstream_of_or_within ISO MGI:1341884 (PMID:15107403) RGD PMID:15107403 NCBI chr 2:95,003,935...95,006,457
Ensembl chr 2:93,095,498...93,100,312 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 acts_upstream_of_or_within ISO
IEA		 MGI:1341800 (PMID:15107403)
GO_REF:0000107		 RGD
Ensembl		 PMID:15107403 GO_REF:0000107 NCBI chr 1:28,641,100...28,651,187
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
G Kdr kinase insert domain receptor acts_upstream_of_or_within ISO
IEA		 MGI:3530468 (PMID:15644447)
GO_REF:0000107		 RGD
Ensembl		 PMID:15644447 GO_REF:0000107 NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Lipa lipase A, lysosomal acid type acts_upstream_of_or_within ISO
IEA		 MGI:6364606 (PMID:33357458)
GO_REF:0000107		 RGD
Ensembl		 PMID:33357458 GO_REF:0000107 NCBI chr 1:241,437,524...241,470,936
Ensembl chr 1:232,024,356...232,057,633 		JBrowse link
G Prox1 prospero homeobox 1 acts_upstream_of_or_within ISO
IEA		 MGI:2386336 (PMID:11927535)
GO_REF:0000107		 RGD
Ensembl		 PMID:11927535 GO_REF:0000107 NCBI chr13:104,196,615...104,251,007
Ensembl chr13:101,669,184...101,711,183 		JBrowse link
arterial endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 involved_in ISO UniProtKB:Q9QUS4 (PMID:15107403) RGD PMID:15107403 NCBI chr 2:95,003,935...95,006,457
Ensembl chr 2:93,095,498...93,100,312 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 involved_in ISO
IEA		 UniProtKB:Q9WV93 (PMID:15107403)
GO_REF:0000107		 RGD
Ensembl		 PMID:15107403 GO_REF:0000107 NCBI chr 1:28,641,100...28,651,187
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO
IEA		 (PMID:15107403)
GO_REF:0000107		 RGD
Ensembl		 PMID:15107403 GO_REF:0000107 NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Tmem100 transmembrane protein 100 acts_upstream_of_or_within ISO
IEA		 MGI:5432904|MGI:5432905 (PMID:22783020)
GO_REF:0000107		 RGD
Ensembl		 PMID:22783020 GO_REF:0000107 NCBI chr10:75,351,891...75,357,748
Ensembl chr10:74,854,468...74,862,941 		JBrowse link
arterial endothelial cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO (PMID:15466160) RGD PMID:15466160 NCBI chr14:61,551,366...61,736,220
Ensembl chr14:57,338,507...57,523,353 		JBrowse link
blood vessel endothelial cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO UniProtKB:P52800 (PMID:15466160) RGD PMID:15466160 NCBI chr14:61,551,366...61,736,220
Ensembl chr14:57,338,507...57,523,353 		JBrowse link
endothelial tip cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll1 delta like canonical Notch ligand 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:22282195)		 UniProt
RGD		 PMID:22282195 GO_REF:0000024 NCBI chr 1:64,985,161...64,993,274
Ensembl chr 1:56,312,066...56,320,179 		JBrowse link
G Flvcr2 FLVCR choline and putative heme transporter 2 acts_upstream_of_or_within ISO (PMID:32369453) RGD PMID:32369453 NCBI chr 6:111,139,352...111,203,345
Ensembl chr 6:105,408,339...105,472,353 		JBrowse link
negative regulation of blood vessel endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxj2 forkhead box J2 involved_in ISO
IEA		 (PMID:24792364)
GO_REF:0000107		 RGD
Ensembl		 PMID:24792364 GO_REF:0000107 NCBI chr 4:157,718,990...157,745,468
Ensembl chr 4:156,046,969...156,073,518 		JBrowse link
Notch signaling pathway involved in arterial endothelial cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll1 delta like canonical Notch ligand 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19144989)		 UniProt
RGD		 PMID:19144989 GO_REF:0000024 NCBI chr 1:64,985,161...64,993,274
Ensembl chr 1:56,312,066...56,320,179 		JBrowse link
positive regulation of blood vessel endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir34a microRNA 34a involved_in ISO (PMID:24792364) RGD PMID:24792364 NCBI chr 5:165,815,952...165,816,053
Ensembl chr 5:160,533,002...160,533,103 		JBrowse link
venous endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Notch1 notch receptor 1 involved_in ISO
IEA		 (PMID:20890042)
GO_REF:0000107		 RGD
Ensembl		 PMID:20890042 GO_REF:0000107 NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    developmental process 7149
      anatomical structure development 6646
        blood vessel development 863
          blood vessel endothelial cell differentiation 13
            arterial endothelial cell differentiation + 6
            blood vessel endothelial cell fate commitment + 3
            cardiac blood vessel endothelial cell differentiation 0
            negative regulation of blood vessel endothelial cell differentiation + 1
            positive regulation of blood vessel endothelial cell differentiation + 1
            regulation of blood vessel endothelial cell differentiation + 2
            venous endothelial cell differentiation + 1
Path 2
Term Annotations click to browse term
  biological_process 20558
    developmental process 7149
      anatomical structure development 6646
        multicellular organism development 5353
          system development 4635
            circulatory system development 1387
              vasculature development 905
                blood vessel development 863
                  blood vessel endothelial cell differentiation 13
                    arterial endothelial cell differentiation + 6
                    blood vessel endothelial cell fate commitment + 3
                    cardiac blood vessel endothelial cell differentiation 0
                    negative regulation of blood vessel endothelial cell differentiation + 1
                    positive regulation of blood vessel endothelial cell differentiation + 1
                    regulation of blood vessel endothelial cell differentiation + 2
                    venous endothelial cell differentiation + 1
paths to the root