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ONTOLOGY REPORT - ANNOTATIONS

Term:blood vessel endothelial cell differentiation
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Accession:GO:0060837 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels.

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blood vessel endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccm2 CCM2 scaffold protein acts_upstream_of_or_within ISO MGI:3512761 (MGI:3837878|PMID:19151727) RGD PMID:19151727 MGI:3837878 NCBI chr14:86,812,728...86,859,408
Ensembl chr14:86,813,082...86,859,406 		JBrowse link
arterial endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 involved_in ISO UniProtKB:Q9QUS4 (MGI:3040159|PMID:15107403) RGD PMID:15107403 MGI:3040159 NCBI chr 2:95,320,147...95,322,701
Ensembl chr 2:95,320,283...95,322,696 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 involved_in ISO UniProtKB:Q9WV93 (MGI:3040159|PMID:15107403) RGD PMID:15107403 MGI:3040159 NCBI chr 1:29,191,170...29,201,257
Ensembl chr 1:29,191,192...29,201,531 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (MGI:3040159|PMID:15107403) RGD PMID:15107403 MGI:3040159 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025 		JBrowse link
G Tmem100 transmembrane protein 100 acts_upstream_of_or_within ISO MGI:5432904|MGI:5432905 (MGI:5432418|PMID:22783020) RGD PMID:22783020 MGI:5432418 NCBI chr10:77,537,340...77,543,710
Ensembl chr10:77,537,340...77,543,192 		JBrowse link
arterial endothelial cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO (MGI:3056004|PMID:15466160) RGD PMID:15466160 MGI:3056004 NCBI chr14:59,657,738...59,865,427
Ensembl chr14:59,658,935...59,735,450 		JBrowse link
blood vessel endothelial cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO UniProtKB:P52800 (MGI:3056004|PMID:15466160) RGD PMID:15466160 MGI:3056004 NCBI chr14:59,657,738...59,865,427
Ensembl chr14:59,658,935...59,735,450 		JBrowse link
endothelial tip cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll1 delta like canonical Notch ligand 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5466218|PMID:22282195)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:22282195 GO_REF:0000024 GO_REF:0000107 MGI:5466218 NCBI chr 1:57,318,621...57,326,732
Ensembl chr 1:57,318,708...57,327,379 		JBrowse link
negative regulation of blood vessel endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxj2 forkhead box J2 involved_in ISO (PMID:24792364) RGD PMID:24792364 NCBI chr 4:155,653,446...155,679,815
Ensembl chr 4:155,653,718...155,679,793 		JBrowse link
Notch signaling pathway involved in arterial endothelial cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll1 delta like canonical Notch ligand 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:3847069|PMID:19144989)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:19144989 GO_REF:0000024 GO_REF:0000107 MGI:3847069 NCBI chr 1:57,318,621...57,326,732
Ensembl chr 1:57,318,708...57,327,379 		JBrowse link
venous endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Notch1 notch receptor 1 involved_in ISO (MGI:4837019|PMID:20890042) RGD PMID:20890042 MGI:4837019 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19610
    developmental process 6757
      anatomical structure development 6182
        blood vessel development 738
          blood vessel endothelial cell differentiation 8
            arterial endothelial cell differentiation + 6
            blood vessel endothelial cell fate commitment + 2
            cardiac blood vessel endothelial cell differentiation 0
            negative regulation of blood vessel endothelial cell differentiation + 1
            positive regulation of blood vessel endothelial cell differentiation + 0
            regulation of blood vessel endothelial cell differentiation + 1
            venous endothelial cell differentiation + 1
Path 2
Term Annotations click to browse term
  biological_process 19610
    developmental process 6757
      anatomical structure development 6182
        multicellular organism development 5619
          system development 5290
            circulatory system development 1231
              vasculature development 775
                blood vessel development 738
                  blood vessel endothelial cell differentiation 8
                    arterial endothelial cell differentiation + 6
                    blood vessel endothelial cell fate commitment + 2
                    cardiac blood vessel endothelial cell differentiation 0
                    negative regulation of blood vessel endothelial cell differentiation + 1
                    positive regulation of blood vessel endothelial cell differentiation + 0
                    regulation of blood vessel endothelial cell differentiation + 1
                    venous endothelial cell differentiation + 1
paths to the root