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ONTOLOGY REPORT - ANNOTATIONS

Term:blood vessel endothelial cell differentiation
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Accession:GO:0060837 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels.


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blood vessel endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccm2 CCM2 scaffold protein acts_upstream_of_or_within ISO MGI:3512761 (MGI:3837878|PMID:19151727) RGD PMID:19151727 MGI:3837878 NCBI chr14:81,418,418...81,464,114
Ensembl chr14:81,418,236...81,464,116 		JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 acts_upstream_of_or_within ISO MGI:1341884 (MGI:3040159|PMID:15107403) RGD PMID:15107403 MGI:3040159 NCBI chr 2:93,096,706...93,100,316
Ensembl chr 2:93,095,498...93,100,312 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 acts_upstream_of_or_within ISO MGI:1341800 (MGI:3040159|PMID:15107403) RGD PMID:15107403 MGI:3040159 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
G Kdr kinase insert domain receptor acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:3530468 (MGI:3529425|PMID:15644447)
GO_REF:0000107		 RGD
Ensembl		 PMID:15644447 GO_REF:0000107 MGI:3529425 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Prox1 prospero homeobox 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:2386336 (MGI:2177970|PMID:11927535)
GO_REF:0000107		 RGD
Ensembl		 PMID:11927535 GO_REF:0000107 MGI:2177970 NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183 		JBrowse link
arterial endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 involved_in ISO UniProtKB:Q9QUS4 (MGI:3040159|PMID:15107403) RGD PMID:15107403 MGI:3040159 NCBI chr 2:93,096,706...93,100,316
Ensembl chr 2:93,095,498...93,100,312 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 involved_in ISO UniProtKB:Q9WV93 (MGI:3040159|PMID:15107403) RGD PMID:15107403 MGI:3040159 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (MGI:3040159|PMID:15107403) RGD PMID:15107403 MGI:3040159 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Tmem100 transmembrane protein 100 acts_upstream_of_or_within ISO MGI:5432904|MGI:5432905 (MGI:5432418|PMID:22783020) RGD PMID:22783020 MGI:5432418 NCBI chr10:74,854,779...74,861,147
Ensembl chr10:74,854,468...74,862,941 		JBrowse link
arterial endothelial cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO (MGI:3056004|PMID:15466160) RGD PMID:15466160 MGI:3056004 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353 		JBrowse link
blood vessel endothelial cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO UniProtKB:P52800 (MGI:3056004|PMID:15466160) RGD PMID:15466160 MGI:3056004 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353 		JBrowse link
endothelial tip cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll1 delta like canonical Notch ligand 1 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(MGI:5466218|PMID:22282195)		 Ensembl
UniProt
RGD		 PMID:22282195 GO_REF:0000024 GO_REF:0000107 MGI:5466218 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179 		JBrowse link
negative regulation of blood vessel endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxj2 forkhead box J2 involved_in ISO (PMID:24792364) RGD PMID:24792364 NCBI chr 4:156,047,043...156,073,540
Ensembl chr 4:156,046,969...156,073,518 		JBrowse link
Notch signaling pathway involved in arterial endothelial cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll1 delta like canonical Notch ligand 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:3847069|PMID:19144989)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:19144989 GO_REF:0000024 GO_REF:0000107 MGI:3847069 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179 		JBrowse link
positive regulation of blood vessel endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir34a microRNA 34a involved_in ISO (PMID:24792364) RGD PMID:24792364 NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103 		JBrowse link
venous endothelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Notch1 notch receptor 1 involved_in ISO (MGI:4837019|PMID:20890042) RGD PMID:20890042 MGI:4837019 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18872
    developmental process 6918
      anatomical structure development 6392
        blood vessel development 815
          blood vessel endothelial cell differentiation 11
            arterial endothelial cell differentiation + 6
            blood vessel endothelial cell fate commitment + 2
            cardiac blood vessel endothelial cell differentiation 0
            negative regulation of blood vessel endothelial cell differentiation + 1
            positive regulation of blood vessel endothelial cell differentiation + 1
            regulation of blood vessel endothelial cell differentiation + 2
            venous endothelial cell differentiation + 1
Path 2
Term Annotations click to browse term
  biological_process 18872
    developmental process 6918
      anatomical structure development 6392
        multicellular organism development 5454
          system development 4956
            circulatory system development 1325
              vasculature development 857
                blood vessel development 815
                  blood vessel endothelial cell differentiation 11
                    arterial endothelial cell differentiation + 6
                    blood vessel endothelial cell fate commitment + 2
                    cardiac blood vessel endothelial cell differentiation 0
                    negative regulation of blood vessel endothelial cell differentiation + 1
                    positive regulation of blood vessel endothelial cell differentiation + 1
                    regulation of blood vessel endothelial cell differentiation + 2
                    venous endothelial cell differentiation + 1
paths to the root