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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:smoothened signaling pathway involved in dorsal/ventral neural tube patterning
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Accession:GO:0060831 term browser browse the term
Definition:The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the dorsal/ventral pattern of the neural tube.
Synonyms:exact_synonym: hedgehog signaling pathway involved in dorsal/ventral neural tube patterning;   hh signaling pathway involved in dorsal/ventral neural tube patterning;   smoothened signalling pathway involved in dorsal/ventral neural tube patterning

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smoothened signaling pathway involved in dorsal/ventral neural tube patterning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO (PMID:20159594)
(PMID:17395647)		 MGI PMID:17395647 PMID:20159594 NCBI chrNW_004955459:8,892,917...9,124,672
Ensembl chrNW_004955459:8,892,869...9,118,499 		JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO (PMID:20159594)
(PMID:17395647)		 MGI PMID:17395647 PMID:20159594 NCBI chrNW_004955460:1,528,457...1,805,584
Ensembl chrNW_004955460:1,528,412...1,805,918 		JBrowse link
G Ift122 intraflagellar transport 122 acts_upstream_of_or_within ISO (PMID:22689656) MGI PMID:22689656 NCBI chrNW_004955429:17,795,757...17,858,609
Ensembl chrNW_004955429:17,794,879...17,858,609 		JBrowse link
G Tbc1d32 TBC1 domain family member 32 acts_upstream_of_or_within ISO (PMID:20159594) MGI PMID:20159594 NCBI chrNW_004955436:3,385,216...3,542,497
Ensembl chrNW_004955436:3,386,180...3,540,933 		JBrowse link
G Tulp3 TUB like protein 3 acts_upstream_of_or_within ISO (PMID:19223390) MGI PMID:19223390 NCBI chrNW_004955429:18,424,912...18,484,522
Ensembl chrNW_004955429:18,453,311...18,482,400 		JBrowse link
G Wdr19 WD repeat domain 19 acts_upstream_of_or_within ISO (PMID:22689656) MGI PMID:22689656 NCBI chrNW_004955443:8,053,847...8,122,918
Ensembl chrNW_004955443:8,053,847...8,123,110 		JBrowse link
negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpr161 G protein-coupled receptor 161 involved_in ISO (MGI:5468365|PMID:23332756) UniProt PMID:23332756 MGI:5468365 NCBI chrNW_004955462:8,981,729...9,034,009
Ensembl chrNW_004955462:8,981,157...9,028,946 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12346
    cellular process 11480
      signal transduction 3950
        cell surface receptor signaling pathway 2177
          smoothened signaling pathway 161
            smoothened signaling pathway involved in dorsal/ventral neural tube patterning 7
              negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning 1
              positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning 0
              regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning + 1
Path 2
Term Annotations click to browse term
  biological_process 12346
    developmental process 5853
      anatomical structure development 5540
        multicellular organism development 4550
          embryo development 1224
            embryo development ending in birth or egg hatching 821
              chordate embryonic development 805
                neural tube development 192
                  neural tube patterning 44
                    dorsal/ventral neural tube patterning 25
                      smoothened signaling pathway involved in dorsal/ventral neural tube patterning 7
                        negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning 1
                        positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning 0
                        regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning + 1
paths to the root