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ONTOLOGY REPORT - ANNOTATIONS

Term:random inactivation of X chromosome
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Accession:GO:0060816 term browser browse the term
Definition:Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on either the paternal or maternal X-chromosome in the XX sex.
Synonyms:related_synonym: rXCI


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random inactivation of X chromosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRCA1 BRCA1 DNA repair associated involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12419249) Ensembl
MGI		 PMID:12419249 GO_REF:0000107 NCBI chr17:14,197,946...14,279,064
Ensembl chr17:14,428,526...14,506,815 		JBrowse link
G CDYL chromodomain Y like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:4,607,088...4,790,742
Ensembl chr 6:4,737,306...4,976,777 		JBrowse link
G JARID2 jumonji and AT-rich interaction domain containing 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:27892467) Ensembl
MGI		 PMID:27892467 GO_REF:0000107 NCBI chr 6:15,100,415...15,376,505
Ensembl chr 6:15,466,050...15,739,170 		JBrowse link
G LOC103785028 polycomb protein SUZ12 acts_upstream_of_or_within ISO (PMID:27892467) MGI PMID:27892467 NCBI chr17:24,790,921...24,853,790 JBrowse link
G PCGF3 polycomb group ring finger 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:802,990...874,063
Ensembl chr 4:746,137...805,443 		JBrowse link
G PCGF5 polycomb group ring finger 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:87,908,298...88,029,923
Ensembl chr10:91,492,201...91,549,737 		JBrowse link
G RLIM ring finger protein, LIM domain interacting involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24613346) Ensembl
MGI
TreeGrafter		 PMID:24613346 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:63,834,345...63,865,874
Ensembl chr  X:73,959,365...73,982,412 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16440
    metabolic process 10303
      regulation of metabolic process 6171
        regulation of macromolecule metabolic process 5636
          regulation of macromolecule biosynthetic process 4868
            regulation of gene expression 4750
              epigenetic regulation of gene expression 236
                sex-chromosome dosage compensation 17
                  dosage compensation by inactivation of X chromosome 15
                    random inactivation of X chromosome 7
Path 2
Term Annotations click to browse term
  biological_process 16440
    biological regulation 11453
      regulation of biological process 11104
        regulation of metabolic process 6171
          regulation of biosynthetic process 5056
            regulation of cellular biosynthetic process 4966
              regulation of macromolecule biosynthetic process 4868
                regulation of gene expression 4750
                  negative regulation of gene expression 1228
                    negative regulation of gene expression, epigenetic 137
                      heterochromatin formation 107
                        dosage compensation by inactivation of X chromosome 15
                          random inactivation of X chromosome 7
paths to the root