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ONTOLOGY REPORT - ANNOTATIONS


Term:mammary gland duct morphogenesis
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Accession:GO:0060603 term browser browse the term
Definition:The process in which anatomical structures of the mammary ducts are generated and organized. Mammary ducts are epithelial tubes that transport milk.


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mammary gland duct morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:1857509 (MGI:2151643|PMID:11783999) RGD PMID:11783999 MGI:2151643 NCBI chr13:34,829,021...35,049,172
Ensembl chr13:34,829,139...35,048,444
JBrowse link
G Lrp5 LDL receptor related protein 5 acts_upstream_of_or_within ISO MGI:1298218 (MGI:3849913|PMID:19503830) RGD PMID:19503830 MGI:3849913 NCBI chr 1:218,816,833...218,920,147
Ensembl chr 1:218,816,841...218,920,094
JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:1278315 (MGI:3849913|PMID:19503830) RGD PMID:19503830 MGI:3849913 NCBI chr 4:168,194,054...168,323,962
Ensembl chr 4:168,194,927...168,323,751
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 acts_upstream_of_or_within ISO MGI:1857745 (MGI:3758540|PMID:12198239) RGD PMID:12198239 MGI:3758540 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Ntn1 netrin 1 acts_upstream_of_or_within
involved_in
IEA
ISO
GO_REF:0000107
MGI:1315205 (MGI:3617129|PMID:16439476)
Ensembl
RGD
PMID:16439476 GO_REF:0000107 MGI:3617129 NCBI chr10:54,761,925...54,982,072
Ensembl chr10:54,761,871...54,967,585
JBrowse link
G Ptch1 patched 1 acts_upstream_of_or_within ISO MGI:1857447 (MGI:1346456|PMID:10529434) RGD PMID:10529434 MGI:1346456 NCBI chr17:1,032,242...1,085,885
Ensembl chr17:1,029,048...1,093,873
JBrowse link
G Scrib scribble planar cell polarity protein involved_in ISO (MGI:4359580|PMID:19041750) RGD PMID:19041750 MGI:4359580 NCBI chr 7:117,105,810...117,128,802
Ensembl chr 7:117,105,810...117,128,798
JBrowse link
G Slit2 slit guidance ligand 2 acts_upstream_of_or_within ISO MGI:105088|MGI:2179460 (MGI:3617129|PMID:16439476) RGD PMID:16439476 MGI:3617129 NCBI chr14:66,831,848...67,171,491
Ensembl chr14:66,831,848...67,170,361
JBrowse link
branch elongation involved in mammary gland duct branching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of_or_within ISO MGI:1857258 (MGI:3814777|PMID:18614704) RGD PMID:18614704 MGI:3814777 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
branching involved in mammary gland duct morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07034833.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 Ensembl chr12:53,872...54,885 JBrowse link
G AABR07071701.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 Ensembl chr 8:126,975,833...126,976,850 JBrowse link
G Btrc beta-transducin repeat containing E3 ubiquitin protein ligase acts_upstream_of_or_within ISO MGI:3055737 (MGI:3054694|PMID:15340078) RGD PMID:15340078 MGI:3054694 NCBI chr 1:265,100,094...265,270,263
Ensembl chr 1:265,157,379...265,269,837
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 acts_upstream_of_or_within ISO MGI:2384435 (MGI:3640884|PMID:10804170) RGD PMID:10804170 MGI:3640884 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575
JBrowse link
G Csf1 colony stimulating factor 1 acts_upstream_of_or_within ISO MGI:1856333 (MGI:3640884|PMID:10804170) RGD PMID:10804170 MGI:3640884 NCBI chr 2:210,522,370...210,550,546
Ensembl chr 2:210,522,375...210,550,560
JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 acts_upstream_of_or_within
involved_in
IEA
ISO
GO_REF:0000107
MGI:2388024 (MGI:1932625|PMID:11283268)
Ensembl
RGD
PMID:11283268 GO_REF:0000107 MGI:1932625 NCBI chr20:3,553,430...3,574,959
Ensembl chr20:3,552,929...3,575,780
JBrowse link
G Epha2 Eph receptor A2 involved_in ISO (MGI:5284750|PMID:19321667) RGD PMID:19321667 MGI:5284750 NCBI chr 5:159,845,773...159,874,203
Ensembl chr 5:159,845,774...159,874,206
JBrowse link
G Etv4 ETS variant transcription factor 4 acts_upstream_of_or_within ISO MGI:2445834 (MGI:2667785|PMID:12871699), (MGI:3828920|PMID:18977342) RGD PMID:12871699 PMID:18977342 MGI:2667785 MGI:3828920 NCBI chr10:89,685,058...89,700,300
Ensembl chr10:89,685,058...89,700,283
JBrowse link
G Kdm5b lysine demethylase 5B acts_upstream_of_or_within ISO MGI:4329395 (MGI:5619178|PMID:24802759) RGD PMID:24802759 MGI:5619178 NCBI chr13:51,384,371...51,455,392
Ensembl chr13:51,384,389...51,455,357
JBrowse link
G LOC102554748 nidogen-2-like involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 7:380,313...427,615
Ensembl chr 7:380,741...381,732
JBrowse link
G Lrp5 LDL receptor related protein 5 acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:3663738 (MGI:3692480|PMID:16973609)
PMID:21873635
RGD PMID:16973609, PMID:21873635, PMID:21873635 MGI:3692480, RGD:13792537, RGD:13792537 NCBI chr 1:218,816,833...218,920,147
Ensembl chr 1:218,816,841...218,920,094
JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:2156191 (MGI:3849913|PMID:19503830)
PMID:21873635
RGD PMID:19503830, PMID:21873635, PMID:21873635 MGI:3849913, RGD:13792537, RGD:13792537 NCBI chr 4:168,194,054...168,323,962
Ensembl chr 4:168,194,927...168,323,751
JBrowse link
G Msx2 msh homeobox 2 acts_upstream_of_or_within
involved_in
IEA
ISO
GO_REF:0000107
MGI:1926381 (MGI:1355063|PMID:10742104)
Ensembl
RGD
PMID:10742104 GO_REF:0000107 MGI:1355063 NCBI chr17:11,683,862...11,689,527
Ensembl chr17:11,683,862...11,689,527
JBrowse link
G Pml PML nuclear body scaffold acts_upstream_of_or_within ISO MGI:2429949 (MGI:3839212|PMID:19261859) RGD PMID:19261859 MGI:3839212 NCBI chr 8:63,002,515...63,034,310
Ensembl chr 8:63,004,870...63,034,226
JBrowse link
G Slc12a2 solute carrier family 12 member 2 acts_upstream_of_or_within ISO MGI:1935144 (MGI:2180693|PMID:8864124) RGD PMID:8864124 MGI:2180693 NCBI chr18:52,917,124...52,985,281
Ensembl chr18:52,917,124...52,985,261
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:1857247 (MGI:3589531|PMID:16007215) RGD PMID:16007215 MGI:3589531 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Tbx3 T-box transcription factor 3 acts_upstream_of_or_within ISO MGI:2655214 (MGI:3608166|PMID:16222716) RGD PMID:16222716 MGI:3608166 NCBI chr12:42,479,518...42,494,588
Ensembl chr12:42,480,560...42,492,526
JBrowse link
dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Areg amphiregulin acts_upstream_of_or_within ISO MGI:2176531 (MGI:3703920|PMID:17369357) RGD PMID:17369357 MGI:3703920 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Tfap2c transcription factor AP-2 gamma acts_upstream_of_or_within ISO MGI:3040993 (MGI:4422106|PMID:20131354) RGD PMID:20131354 MGI:4422106 NCBI chr 3:170,550,314...170,558,197
Ensembl chr 3:170,550,314...170,558,194
JBrowse link
epithelial cell proliferation involved in mammary gland duct elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Areg amphiregulin acts_upstream_of_or_within ISO MGI:2176531 (MGI:3703920|PMID:17369357) RGD PMID:17369357 MGI:3703920 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Esr1 estrogen receptor 1 acts_upstream_of_or_within
involved_in
IEA
ISO
GO_REF:0000107
MGI:2150897 (MGI:3629536|PMID:12021201)
Ensembl
RGD
PMID:12021201 GO_REF:0000107 MGI:3629536 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Med1 mediator complex subunit 1 acts_upstream_of_or_within ISO MGI:3511276 (MGI:3576991|PMID:15647257) RGD PMID:15647257 MGI:3576991 NCBI chr10:86,101,560...86,145,271
Ensembl chr10:86,103,600...86,144,880
JBrowse link
G Tfap2c transcription factor AP-2 gamma acts_upstream_of_or_within ISO MGI:3040993 (MGI:4422106|PMID:20131354) RGD PMID:20131354 MGI:4422106 NCBI chr 3:170,550,314...170,558,197
Ensembl chr 3:170,550,314...170,558,194
JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within
involved_in
IEA
ISO
GO_REF:0000107
(MGI:3761053|PMID:17898001)
Ensembl
RGD
PMID:17898001 GO_REF:0000107 MGI:3761053 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
lateral sprouting involved in mammary gland duct morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor acts_upstream_of_or_within
involved_in
IEA
ISO
GO_REF:0000107
MGI:2687199 (MGI:2683859|PMID:14676301)
Ensembl
RGD
PMID:14676301 GO_REF:0000107 MGI:2683859 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within
involved_in
IEA
ISO
GO_REF:0000107
(MGI:3761053|PMID:17898001)
Ensembl
RGD
PMID:17898001 GO_REF:0000107 MGI:3761053 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
mammary duct terminal end bud growth term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl11 C-C motif chemokine ligand 11 acts_upstream_of_or_within ISO MGI:2384435 (MGI:3640884|PMID:10804170) RGD PMID:10804170 MGI:3640884 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575
JBrowse link
G Csf1 colony stimulating factor 1 acts_upstream_of_or_within ISO MGI:1856333 (MGI:3640884|PMID:10804170) RGD PMID:10804170 MGI:3640884 NCBI chr 2:210,522,370...210,550,546
Ensembl chr 2:210,522,375...210,550,560
JBrowse link
G Kdm5b lysine demethylase 5B acts_upstream_of_or_within ISO MGI:4329395 (MGI:5619178|PMID:24802759) RGD PMID:24802759 MGI:5619178 NCBI chr13:51,384,371...51,455,392
Ensembl chr13:51,384,389...51,455,357
JBrowse link
G Mst1 macrophage stimulating 1 acts_upstream_of_or_within ISO MGI:2445230 (MGI:5614192|PMID:25049204) RGD PMID:25049204 MGI:5614192 NCBI chr 8:116,857,716...116,862,286
Ensembl chr 8:116,857,684...116,862,423
JBrowse link
G Robo1 roundabout guidance receptor 1 acts_upstream_of_or_within ISO MGI:3043142 (MGI:3617129|PMID:16439476) RGD PMID:16439476 MGI:3617129 NCBI chr11:9,079,291...10,146,302
Ensembl chr11:9,642,365...10,143,317
JBrowse link
G Slc12a2 solute carrier family 12 member 2 acts_upstream_of_or_within ISO MGI:1935144 (MGI:2180453|PMID:12040017) RGD PMID:12040017 MGI:2180453 NCBI chr18:52,917,124...52,985,281
Ensembl chr18:52,917,124...52,985,261
JBrowse link
G Slit2 slit guidance ligand 2 acts_upstream_of_or_within ISO MGI:2179460 (MGI:3617129|PMID:16439476) RGD PMID:16439476 MGI:3617129 NCBI chr14:66,831,848...67,171,491
Ensembl chr14:66,831,848...67,170,361
JBrowse link
mammary gland branching involved in pregnancy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csmd1 CUB and Sushi multiple domains 1 acts_upstream_of_or_within ISO MGI:5473214 (MGI:6369467|PMID:31604923) RGD PMID:31604923 MGI:6369467 NCBI chr16:77,152,823...78,850,222
Ensembl chr16:78,539,489...78,850,222
JBrowse link
G Esr1 estrogen receptor 1 acts_upstream_of_or_within
involved_in
IEA
ISO
GO_REF:0000107
MGI:2150897 (MGI:1926565|PMID:10919287)
Ensembl
RGD
PMID:10919287 GO_REF:0000107 MGI:1926565 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Med1 mediator complex subunit 1 acts_upstream_of_or_within ISO MGI:3511276 (MGI:3576991|PMID:15647257) RGD PMID:15647257 MGI:3576991 NCBI chr10:86,101,560...86,145,271
Ensembl chr10:86,103,600...86,144,880
JBrowse link
G Vdr vitamin D receptor acts_upstream_of_or_within
involved_in
IEA
ISO
GO_REF:0000107
MGI:2183404 (MGI:3051725|PMID:15178742)
Ensembl
RGD
PMID:15178742 GO_REF:0000107 MGI:3051725 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link
mammary gland branching involved in thelarche term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Areg amphiregulin acts_upstream_of_or_within ISO MGI:2176531 (MGI:1336843|PMID:10331984), (MGI:3703920|PMID:17369357) RGD PMID:10331984 PMID:17369357 MGI:1336843 MGI:3703920 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Med1 mediator complex subunit 1 acts_upstream_of_or_within ISO MGI:3511276 (MGI:3576991|PMID:15647257) RGD PMID:15647257 MGI:3576991 NCBI chr10:86,101,560...86,145,271
Ensembl chr10:86,103,600...86,144,880
JBrowse link
G Ncoa3 nuclear receptor coactivator 3 acts_upstream_of_or_within ISO MGI:1931860 (MGI:1859522|PMID:11015591) RGD PMID:11015591 MGI:1859522 NCBI chr 3:162,692,176...162,788,582
Ensembl chr 3:162,692,185...162,787,548
JBrowse link
G Phb2 prohibitin 2 acts_upstream_of_or_within ISO MGI:3574361 (MGI:3695669|PMID:17065319) RGD PMID:17065319 MGI:3695669 NCBI chr 4:157,230,769...157,235,375
Ensembl chr 4:157,230,769...157,235,367
JBrowse link
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of_or_within ISO MGI:1857258 (MGI:3814777|PMID:18614704) RGD PMID:18614704 MGI:3814777 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within
involved_in
IEA
ISO
GO_REF:0000107
(MGI:3761053|PMID:17898001)
Ensembl
RGD
PMID:17898001 GO_REF:0000107 MGI:3761053 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
mammary gland bud elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pthlh parathyroid hormone-like hormone acts_upstream_of_or_within ISO MGI:2154515 (MGI:1203302|PMID:9477327) RGD PMID:9477327 MGI:1203302 NCBI chr 4:181,663,425...181,674,181 JBrowse link
mammary gland bud formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:1859647 (MGI:2155478|PMID:11782400) RGD PMID:11782400 MGI:2155478 NCBI chr 2:51,673,480...51,747,533
Ensembl chr 2:51,672,722...51,750,369
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO MGI:2153811 (MGI:2155478|PMID:11782400) RGD PMID:11782400 MGI:2155478 NCBI chr 1:200,590,951...200,696,946
Ensembl chr 1:200,590,953...200,696,928
JBrowse link
mammary gland bud morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sostdc1 sclerostin domain containing 1 acts_upstream_of_or_within ISO MGI:3604658 (MGI:5319554|PMID:22509524) RGD PMID:22509524 MGI:5319554 NCBI chr 6:55,812,820...55,816,994
Ensembl chr 6:55,812,747...55,817,066
JBrowse link
regulation of branching involved in mammary gland duct morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 acts_upstream_of_or_within ISO MGI:2180558 (MGI:3830397|PMID:19164602) RGD PMID:19164602 MGI:3830397 NCBI chr 4:144,382,945...144,398,919
Ensembl chr 4:144,382,945...144,398,917
JBrowse link
G Etv5 ETS variant transcription factor 5 acts_upstream_of_or_within ISO (MGI:2667785|PMID:12871699) RGD PMID:12871699 MGI:2667785 NCBI chr11:82,194,657...82,252,145
Ensembl chr11:82,194,657...82,252,139
JBrowse link
G Phb2 prohibitin 2 acts_upstream_of_or_within ISO MGI:3574361 (MGI:3695669|PMID:17065319) RGD PMID:17065319 MGI:3695669 NCBI chr 4:157,230,769...157,235,375
Ensembl chr 4:157,230,769...157,235,367
JBrowse link
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of_or_within ISO MGI:98958 (MGI:3761053|PMID:17898001) RGD PMID:17898001 MGI:3761053 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within
involved_in
IEA
ISO
GO_REF:0000107
MGI:96079|MGI:98725 (MGI:3761053|PMID:17898001)
Ensembl
RGD
PMID:17898001 GO_REF:0000107 MGI:3761053 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
tertiary branching involved in mammary gland duct morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor acts_upstream_of_or_within
involved_in
IEA
ISO
GO_REF:0000107
MGI:2687199 (MGI:2683859|PMID:14676301)
Ensembl
RGD
PMID:14676301 GO_REF:0000107 MGI:2683859 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Pgr progesterone receptor acts_upstream_of_or_within
involved_in
IEA
ISO
GO_REF:0000107
MGI:1857933 (MGI:1354852|PMID:10733525)
Ensembl
RGD
PMID:10733525 GO_REF:0000107 MGI:1354852 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Wnt4 Wnt family member 4 acts_upstream_of_or_within
involved_in
IEA
ISO
GO_REF:0000107
MGI:1857453 (MGI:1354852|PMID:10733525)
Ensembl
RGD
PMID:10733525 GO_REF:0000107 MGI:1354852 NCBI chr 5:155,649,238...155,668,065
Ensembl chr 5:155,649,217...155,672,579
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20082
    developmental process 6853
      anatomical structure morphogenesis 2896
        tube morphogenesis 942
          epithelial tube morphogenesis 404
            mammary gland duct morphogenesis 44
              branching involved in mammary gland duct morphogenesis + 32
              mammary duct terminal end bud growth 7
              mammary gland bud morphogenesis + 4
              mammary gland cord morphogenesis + 0
              mammary gland duct cavitation 0
              mammary gland duct regression in males 0
Path 2
Term Annotations click to browse term
  biological_process 20082
    developmental process 6853
      anatomical structure development 6313
        multicellular organism development 5789
          system development 5317
            animal organ development 4068
              animal organ morphogenesis 1158
                gland morphogenesis 168
                  mammary gland morphogenesis 67
                    mammary gland duct morphogenesis 44
                      branching involved in mammary gland duct morphogenesis + 32
                      mammary duct terminal end bud growth 7
                      mammary gland bud morphogenesis + 4
                      mammary gland cord morphogenesis + 0
                      mammary gland duct cavitation 0
                      mammary gland duct regression in males 0
paths to the root