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ONTOLOGY REPORT - ANNOTATIONS


Term:mammary gland duct morphogenesis
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Accession:GO:0060603 term browser browse the term
Definition:The process in which anatomical structures of the mammary ducts are generated and organized. Mammary ducts are epithelial tubes that transport milk.



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mammary gland duct morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csmd1 CUB and Sushi multiple domains 1 acts_upstream_of_or_within ISO (PMID:33530646) RGD PMID:33530646 NCBI chr16:72,218,189...73,818,380
Ensembl chr16:72,218,503...73,817,614
JBrowse link
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:1857509 (PMID:11783999) RGD PMID:11783999 NCBI chr13:29,946,882...30,163,589
Ensembl chr13:29,946,809...30,163,574
JBrowse link
G Lrp5 LDL receptor related protein 5 acts_upstream_of_or_within ISO MGI:1298218 (PMID:19503830) RGD PMID:19503830 NCBI chr 1:200,814,247...200,917,581
Ensembl chr 1:200,814,250...200,917,581
JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:1278315 (PMID:19503830) RGD PMID:19503830 NCBI chr 4:167,269,856...167,400,364
Ensembl chr 4:167,270,353...167,400,497
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857745 (PMID:12198239)
Ensembl
RGD
PMID:12198239 GO_REF:0000107 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Ntn1 netrin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1315205 (PMID:16439476)
Ensembl
RGD
PMID:16439476 GO_REF:0000107 NCBI chr10:52,899,933...53,098,591
Ensembl chr10:52,899,934...53,085,326
JBrowse link
G Perp p53 apoptosis effector related to PMP22 involved_in ISO (PMID:22515648) RGD PMID:22515648 NCBI chr 1:13,542,067...13,554,514
Ensembl chr 1:13,542,067...13,554,511
JBrowse link
G Ptch1 patched 1 acts_upstream_of_or_within ISO MGI:1857447 (PMID:10529434) RGD PMID:10529434 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333
JBrowse link
G Scrib scribble planar cell polarity protein involved_in ISO (PMID:19041750) RGD PMID:19041750 NCBI chr 7:107,759,343...107,782,364
Ensembl chr 7:107,759,343...107,782,331
JBrowse link
G Slit2 slit guidance ligand 2 acts_upstream_of_or_within ISO MGI:105088|MGI:2179460 (PMID:16439476) RGD PMID:16439476 NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948
JBrowse link
branch elongation involved in mammary gland duct branching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of_or_within ISO MGI:1857258 (PMID:18614704) RGD PMID:18614704 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
branching involved in mammary gland duct morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btrc beta-transducin repeat containing E3 ubiquitin protein ligase acts_upstream_of_or_within ISO MGI:3055737 (PMID:15340078) RGD PMID:15340078 NCBI chr 1:244,210,299...244,380,126
Ensembl chr 1:244,210,314...244,376,721
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 acts_upstream_of_or_within ISO MGI:2384435 (PMID:10804170) RGD PMID:10804170 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
JBrowse link
G Csf1 colony stimulating factor 1 acts_upstream_of_or_within ISO MGI:1856333 (PMID:10804170) RGD PMID:10804170 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:2388024 (PMID:11283268)
GO_REF:0000107
RGD
Ensembl
PMID:11283268 GO_REF:0000107 NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468
JBrowse link
G Epha2 Eph receptor A2 involved_in ISO (PMID:19321667) RGD PMID:19321667 NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117
JBrowse link
G Etv4 ETS variant transcription factor 4 acts_upstream_of_or_within ISO MGI:2445834 (PMID:12871699), (PMID:18977342) RGD PMID:12871699 PMID:18977342 NCBI chr10:86,706,749...86,721,974
Ensembl chr10:86,706,749...86,721,974
JBrowse link
G Kdm5b lysine demethylase 5B acts_upstream_of_or_within ISO MGI:4329395 (PMID:24802759) RGD PMID:24802759 NCBI chr13:46,001,589...46,073,868
Ensembl chr13:46,002,542...46,073,872
JBrowse link
G Lrp5 LDL receptor related protein 5 acts_upstream_of_or_within ISO MGI:3663738 (PMID:16973609) RGD PMID:16973609 NCBI chr 1:200,814,247...200,917,581
Ensembl chr 1:200,814,250...200,917,581
JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:2156191 (PMID:19503830) RGD PMID:19503830 NCBI chr 4:167,269,856...167,400,364
Ensembl chr 4:167,270,353...167,400,497
JBrowse link
G Msx2 msh homeobox 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1926381 (PMID:10742104)
Ensembl
RGD
PMID:10742104 GO_REF:0000107 NCBI chr17:11,097,214...11,102,879
Ensembl chr17:11,097,103...11,102,879
JBrowse link
G Pml PML nuclear body scaffold acts_upstream_of_or_within ISO MGI:2429949 (PMID:19261859) RGD PMID:19261859 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
JBrowse link
G Slc12a2 solute carrier family 12 member 2 acts_upstream_of_or_within ISO MGI:1935144 (PMID:8864124) RGD PMID:8864124 NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:1857247 (PMID:16007215) RGD PMID:16007215 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Tbx3 T-box transcription factor 3 acts_upstream_of_or_within ISO MGI:2655214 (PMID:16222716) RGD PMID:16222716 NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708
JBrowse link
dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Areg amphiregulin acts_upstream_of_or_within ISO MGI:2176531 (PMID:17369357) RGD PMID:17369357 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
JBrowse link
G Tfap2c transcription factor AP-2 gamma acts_upstream_of_or_within ISO MGI:3040993 (PMID:20131354) RGD PMID:20131354 NCBI chr 3:161,315,114...161,322,998
Ensembl chr 3:161,315,031...161,322,995
JBrowse link
epithelial cell proliferation involved in mammary gland duct elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Areg amphiregulin acts_upstream_of_or_within ISO MGI:2176531 (PMID:17369357) RGD PMID:17369357 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
JBrowse link
G Esr1 estrogen receptor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2150897 (PMID:12021201)
Ensembl
RGD
PMID:12021201 GO_REF:0000107 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Med1 mediator complex subunit 1 acts_upstream_of_or_within ISO MGI:3511276 (PMID:15647257) RGD PMID:15647257 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299
JBrowse link
G Tfap2c transcription factor AP-2 gamma acts_upstream_of_or_within ISO MGI:3040993 (PMID:20131354) RGD PMID:20131354 NCBI chr 3:161,315,114...161,322,998
Ensembl chr 3:161,315,031...161,322,995
JBrowse link
G Wnt5a Wnt family member 5A involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:17898001)
Ensembl
RGD
PMID:17898001 GO_REF:0000107 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234
JBrowse link
lateral sprouting involved in mammary gland duct morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2687199 (PMID:14676301)
Ensembl
RGD
PMID:14676301 GO_REF:0000107 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Wnt5a Wnt family member 5A involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:17898001)
Ensembl
RGD
PMID:17898001 GO_REF:0000107 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234
JBrowse link
mammary duct terminal end bud growth term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor IDA RGD PMID:26372666 RGD:407419879 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 acts_upstream_of_or_within ISO MGI:2384435 (PMID:10804170) RGD PMID:10804170 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
JBrowse link
G Csf1 colony stimulating factor 1 acts_upstream_of_or_within ISO MGI:1856333 (PMID:10804170) RGD PMID:10804170 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
JBrowse link
G Kdm5b lysine demethylase 5B acts_upstream_of_or_within ISO MGI:4329395 (PMID:24802759) RGD PMID:24802759 NCBI chr13:46,001,589...46,073,868
Ensembl chr13:46,002,542...46,073,872
JBrowse link
G Mst1 macrophage stimulating 1 acts_upstream_of_or_within ISO MGI:2445230 (PMID:25049204) RGD PMID:25049204 NCBI chr 8:108,767,886...108,773,425
Ensembl chr 8:108,768,839...108,773,416
JBrowse link
G Robo1 roundabout guidance receptor 1 acts_upstream_of_or_within ISO MGI:3043142 (PMID:16439476) RGD PMID:16439476 NCBI chr11:10,580,863...11,621,675
Ensembl chr11:10,580,908...11,620,203
JBrowse link
G Slc12a2 solute carrier family 12 member 2 acts_upstream_of_or_within ISO MGI:1935144 (PMID:12040017) RGD PMID:12040017 NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440
JBrowse link
G Slit2 slit guidance ligand 2 acts_upstream_of_or_within ISO MGI:2179460 (PMID:16439476) RGD PMID:16439476 NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948
JBrowse link
mammary gland branching involved in pregnancy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csmd1 CUB and Sushi multiple domains 1 acts_upstream_of_or_within ISO MGI:5473214 (PMID:31604923) RGD PMID:31604923 NCBI chr16:72,218,189...73,818,380
Ensembl chr16:72,218,503...73,817,614
JBrowse link
G Esr1 estrogen receptor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2150897 (PMID:10919287)
Ensembl
RGD
PMID:10919287 GO_REF:0000107 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Med1 mediator complex subunit 1 acts_upstream_of_or_within ISO MGI:3511276 (PMID:15647257) RGD PMID:15647257 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299
JBrowse link
G Vdr vitamin D receptor involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2183404 (PMID:15178742)
Ensembl
RGD
PMID:15178742 GO_REF:0000107 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
JBrowse link
mammary gland branching involved in thelarche term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Areg amphiregulin acts_upstream_of_or_within ISO MGI:2176531 (PMID:10331984), (PMID:17369357) RGD PMID:10331984 PMID:17369357 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
JBrowse link
G Med1 mediator complex subunit 1 acts_upstream_of_or_within ISO MGI:3511276 (PMID:15647257) RGD PMID:15647257 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299
JBrowse link
G Ncoa3 nuclear receptor coactivator 3 acts_upstream_of_or_within ISO MGI:1931860 (PMID:11015591) RGD PMID:11015591 NCBI chr 3:154,738,566...154,821,395
Ensembl chr 3:154,738,581...154,818,594
JBrowse link
G Phb2 prohibitin 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3574361 (PMID:17065319)
Ensembl
RGD
PMID:17065319 GO_REF:0000107 NCBI chr 4:157,517,662...157,522,268
Ensembl chr 4:157,517,577...157,522,272
JBrowse link
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of_or_within ISO MGI:1857258 (PMID:18614704) RGD PMID:18614704 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Wnt5a Wnt family member 5A involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:17898001)
Ensembl
RGD
PMID:17898001 GO_REF:0000107 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234
JBrowse link
mammary gland bud elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pthlh parathyroid hormone-like hormone acts_upstream_of_or_within ISO MGI:2154515 (PMID:9477327) RGD PMID:9477327 NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847
JBrowse link
mammary gland bud formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:1859647 (PMID:11782400) RGD PMID:11782400 NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO MGI:2153811 (PMID:11782400) RGD PMID:11782400 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
JBrowse link
mammary gland bud morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sostdc1 sclerostin domain containing 1 acts_upstream_of_or_within ISO MGI:3604658 (PMID:22509524) RGD PMID:22509524 NCBI chr 6:53,051,336...53,055,510
Ensembl chr 6:53,051,354...53,055,579
JBrowse link
regulation of branching involved in mammary gland duct morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 acts_upstream_of_or_within ISO MGI:2180558 (PMID:19164602) RGD PMID:19164602 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137
JBrowse link
G Etv5 ETS variant transcription factor 5 acts_upstream_of_or_within ISO (PMID:12871699) RGD PMID:12871699 NCBI chr11:78,608,618...78,666,221
Ensembl chr11:78,608,710...78,666,215
JBrowse link
G Phb2 prohibitin 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3574361 (PMID:17065319)
Ensembl
RGD
PMID:17065319 GO_REF:0000107 NCBI chr 4:157,517,662...157,522,268
Ensembl chr 4:157,517,577...157,522,272
JBrowse link
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of_or_within ISO MGI:98958 (PMID:17898001) RGD PMID:17898001 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Wnt5a Wnt family member 5A involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:96079|MGI:98725 (PMID:17898001)
Ensembl
RGD
PMID:17898001 GO_REF:0000107 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234
JBrowse link
tertiary branching involved in mammary gland duct morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2687199 (PMID:14676301)
Ensembl
RGD
PMID:14676301 GO_REF:0000107 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Pgr progesterone receptor involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857933 (PMID:10733525)
Ensembl
RGD
PMID:10733525 GO_REF:0000107 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Wnt4 Wnt family member 4 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:1857453 (PMID:10733525)
GO_REF:0000107
RGD
Ensembl
PMID:10733525 GO_REF:0000107 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20537
    developmental process 7105
      anatomical structure morphogenesis 3005
        tube morphogenesis 1042
          epithelial tube morphogenesis 404
            mammary gland duct morphogenesis 43
              branching involved in mammary gland duct morphogenesis + 29
              mammary duct terminal end bud growth 8
              mammary gland bud morphogenesis + 4
              mammary gland cord morphogenesis + 0
              mammary gland duct cavitation 0
              mammary gland duct regression in males 0
Path 2
Term Annotations click to browse term
  biological_process 20537
    developmental process 7105
      anatomical structure development 6607
        anatomical structure morphogenesis 3005
          animal organ morphogenesis 1170
            gland morphogenesis 170
              mammary gland morphogenesis 68
                mammary gland duct morphogenesis 43
                  branching involved in mammary gland duct morphogenesis + 29
                  mammary duct terminal end bud growth 8
                  mammary gland bud morphogenesis + 4
                  mammary gland cord morphogenesis + 0
                  mammary gland duct cavitation 0
                  mammary gland duct regression in males 0
paths to the root