Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap)  (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer) Overgo Probe Designer
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:multicellular organismal-level iron ion homeostasis
go back to main search page
Accession:GO:0060586 term browser browse the term
Definition:A chemical homeostatic process involved in the maintenance of a steady state level of iron within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell.
Synonyms:exact_synonym: multicellular organismal iron ion homeostasis


show annotations for term's descendants           Sort by:
multicellular organismal-level iron ion homeostasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank1 ankyrin 1 acts_upstream_of_or_within ISO MGI:5502651 (MGI:5502531|PMID:23390527) RGD PMID:23390527 MGI:5502531 NCBI chr16:68,876,294...69,054,812
Ensembl chr16:68,877,504...69,054,759 		JBrowse link
G B2m beta-2 microglobulin acts_upstream_of_or_within ISO (MGI:1931896|PMID:11113132) RGD PMID:11113132 MGI:1931896 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766 		JBrowse link
G Bmp6 bone morphogenetic protein 6 involved_in ISO
ISS		 (MGI:4352622|PMID:19252488)
(PMID:26582087), (PMID:28335084), (PMID:32464486)
GO_REF:0000024		 RGD
UniProt		 PMID:19252488 PMID:26582087 PMID:28335084 PMID:32464486 GO_REF:0000024 MGI:4352622 NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Btbd9 BTB domain containing 9 acts_upstream_of_or_within ISO MGI:4127237 (MGI:5436392|PMID:22678064) RGD PMID:22678064 MGI:5436392 NCBI chr20:8,286,337...8,645,567
Ensembl chr20:8,288,711...8,643,960 		JBrowse link
G Cybrd1 cytochrome b reductase 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:30272000)		 UniProt
RGD		 PMID:30272000 GO_REF:0000024 NCBI chr 3:55,934,874...55,962,132
Ensembl chr 3:55,934,874...55,962,108 		JBrowse link
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:2679454 (MGI:3763756|PMID:17932563)
GO_REF:0000107		 RGD
Ensembl		 PMID:17932563 GO_REF:0000107 MGI:3763756 NCBI chr12:10,710,771...10,744,597
Ensembl chr12:10,705,874...10,744,573 		JBrowse link
G Epas1 endothelial PAS domain protein 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:109169 (MGI:5314161|PMID:22128145)
GO_REF:0000107		 RGD
Ensembl		 PMID:22128145 GO_REF:0000107 MGI:5314161 NCBI chr 6:7,790,236...7,871,246
Ensembl chr 6:7,790,647...7,871,228 		JBrowse link
G Epb42 erythrocyte membrane protein band 4.2 acts_upstream_of_or_within ISO MGI:2182816 (MGI:1930623|PMID:10359562) RGD PMID:10359562 MGI:1930623 NCBI chr 3:107,979,709...107,997,932
Ensembl chr 3:107,979,713...107,997,932 		JBrowse link
G Fbxl5 F-box and leucine-rich repeat protein 5 acts_upstream_of_or_within ISO MGI:1928268|MGI:5295288 (MGI:5292406|PMID:21907140) RGD PMID:21907140 MGI:5292406 NCBI chr14:67,305,109...67,347,383
Ensembl chr14:67,267,801...67,347,383 		JBrowse link
G Fech ferrochelatase acts_upstream_of_or_within ISO MGI:1858114 (MGI:3818407|PMID:17003376) RGD PMID:17003376 MGI:3818407 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348 		JBrowse link
G Hamp hepcidin antimicrobial peptide involved_in
acts_upstream_of_or_within		 ISO (PMID:12469120)
MGI:3701082|MGI:4351741 (MGI:3700987|PMID:16574947), (MGI:4820950|PMID:20113314), (MGI:4829573|PMID:20530874), (MGI:4950359|PMID:20811044), (MGI:5314161|PMID:22128145), (MGI:5508856|PMID:23637785), (MGI:5564843|PMID:24357728), (MGI:5575845|PMID:24646470), (MGI:5581387|PMID:24561287)		 RGD PMID:12469120 PMID:16574947 PMID:20113314 PMID:20530874 PMID:20811044 More... MGI:3700987 MGI:4820950 MGI:4829573 MGI:4950359 MGI:5314161 MGI:5508856 MGI:5564843 MGI:5575845 MGI:5581387 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891 		JBrowse link
G Hfe homeostatic iron regulator involved_in
acts_upstream_of_or_within		 IEP
ISO
IEA		 (PMID:21173098)
MGI:1934013|MGI:2181388|MGI:2385353|MGI:3775648 (MGI:1332955|PMID:10077651), (MGI:3043987|PMID:15131800), (MGI:3700581|PMID:15914561), (MGI:4888467|PMID:21059897), (MGI:5467909|PMID:22960056)
GO_REF:0000107		 RGD
Ensembl		 PMID:10077651 PMID:15131800 PMID:15914561 PMID:21059897 PMID:21173098 More... GO_REF:0000107 MGI:1332955 MGI:3043987 MGI:3700581 MGI:4888467 MGI:5467909, RGD:1582699 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502 		JBrowse link
G Hjv hemojuvelin BMP co-receptor acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:3587746|MGI:3587747 (MGI:3587447|PMID:16075058), (MGI:5314735|PMID:19751239), (MGI:5467909|PMID:22960056), (MGI:5578296|PMID:24409331)
UniProtKB:Q92859 (PMID:16075058)
GO_REF:0000107		 RGD
Ensembl		 PMID:16075058 PMID:19751239 PMID:22960056 PMID:24409331 GO_REF:0000107 MGI:3587447 MGI:5314735 MGI:5467909 MGI:5578296 NCBI chr 2:184,065,970...184,069,851
Ensembl chr 2:184,065,970...184,069,850 		JBrowse link
G Hmox1 heme oxygenase 1 involved_in ISO (PMID:9884342) RGD PMID:9884342 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Htt huntingtin acts_upstream_of_or_within ISO MGI:1857180 (MGI:3619161|PMID:11092755) RGD PMID:11092755 MGI:3619161 NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070 		JBrowse link
G Hyal2 hyaluronidase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3836764 (MGI:3836537|PMID:18772348)		 Ensembl
RGD		 PMID:18772348 GO_REF:0000107 MGI:3836537 NCBI chr 8:108,241,895...108,246,853
Ensembl chr 8:108,243,133...108,246,850 		JBrowse link
G Ireb2 iron responsive element binding protein 2 acts_upstream_of_or_within ISO MGI:2152883 (MGI:5292406|PMID:21907140) RGD PMID:21907140 MGI:5292406 NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611 		JBrowse link
G Mir122 microRNA 122 acts_upstream_of_or_within ISO MGI:2676805 (MGI:5002780|PMID:21364282) RGD PMID:21364282 MGI:5002780 NCBI chr18:58,758,703...58,758,787 JBrowse link
G Mir17 microRNA 17 acts_upstream_of_or_within ISO (MGI:5002780|PMID:21364282) RGD PMID:21364282 MGI:5002780 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712 		JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within ISO MGI:1934018 (MGI:6285478|PMID:29624734) RGD PMID:29624734 MGI:6285478 NCBI chr10:86,001,545...86,009,049
Ensembl chr10:86,001,566...86,008,972 		JBrowse link
G Neo1 neogenin 1 acts_upstream_of_or_within ISO UniProtKB:Q6ZVN8 (PMID:16075058) RGD PMID:16075058 NCBI chr 8:59,273,860...59,426,486
Ensembl chr 8:59,275,569...59,430,348 		JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:22952941)
GO_REF:0000024		 Ensembl
RGD
Alzheimers_University_of_Toronto		 PMID:22952941 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:144,056,415...144,138,045
Ensembl chr 1:144,056,721...144,137,557 		JBrowse link
G Rhag Rh-associated glycoprotein involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:5318589 (MGI:5314734|PMID:19807729)		 Ensembl
RGD		 PMID:19807729 GO_REF:0000107 MGI:5314734 NCBI chr 9:20,069,800...20,097,836
Ensembl chr 9:20,069,807...20,097,836 		JBrowse link
G Rhd Rh blood group, D antigen acts_upstream_of_or_within ISO MGI:5318588 (MGI:5314734|PMID:19807729) RGD PMID:19807729 MGI:5314734 NCBI chr 5:147,087,479...147,121,716
Ensembl chr 5:147,087,518...147,121,715 		JBrowse link
G Slc11a1 solute carrier family 11 member 1 acts_upstream_of_or_within ISO MGI:1857755|MGI:2446573 (MGI:1309584|PMID:9824471), (MGI:3841492|PMID:19321419) RGD PMID:9824471 PMID:19321419 MGI:1309584 MGI:3841492 NCBI chr 9:75,957,193...75,968,115
Ensembl chr 9:75,957,316...75,968,101 		JBrowse link
G Slc11a2 solute carrier family 11 member 2 involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 GO_REF:0000107
PMID:21873635
MGI:1856400 (MGI:3793885|PMID:18076961), (MGI:53771|PMID:5070129)
(PMID:15459009)		 Ensembl
RGD		 PMID:5070129 PMID:15459009 PMID:18076961 PMID:21873635 GO_REF:0000107 MGI:3793885 MGI:53771, RGD:13792537 NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145 		JBrowse link
G Slc40a1 solute carrier family 40 member 1 involved_in
acts_upstream_of_or_within		 ISO (MGI:3039043|PMID:15084469)
MGI:1889622 (MGI:3578034|PMID:15342464), (MGI:4430176|PMID:19596281)		 RGD PMID:15084469 PMID:15342464 PMID:19596281 MGI:3039043 MGI:3578034 MGI:4430176 NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481 		JBrowse link
G Sod2 superoxide dismutase 2 acts_upstream_of_or_within ISO MGI:1857344 (MGI:3505659|PMID:15205258) RGD PMID:15205258 MGI:3505659 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Tfr2 transferrin receptor 2 acts_upstream_of_or_within
involved_in		 ISO MGI:2384726 (MGI:5467909|PMID:22960056)
(PMID:21173098)		 RGD PMID:21173098 PMID:22960056 MGI:5467909 NCBI chr12:19,107,673...19,124,622
Ensembl chr12:19,107,673...19,124,591 		JBrowse link
G Tmprss6 transmembrane serine protease 6 acts_upstream_of_or_within
involved_in		 ISO MGI:3776631 (MGI:5314735|PMID:19751239)
(PMID:18408718)		 RGD PMID:18408718 PMID:19751239 MGI:5314735 NCBI chr 7:109,991,008...110,021,626
Ensembl chr 7:109,985,931...110,021,624 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19748
    multicellular organismal process 9185
      multicellular organismal-level homeostasis 910
        multicellular organismal-level chemical homeostasis 81
          multicellular organismal-level iron ion homeostasis 30
Path 2
Term Annotations click to browse term
  biological_process 19748
    homeostatic process 1915
      chemical homeostasis 1172
        monoatomic ion homeostasis 656
          monoatomic cation homeostasis 644
            multicellular organismal-level iron ion homeostasis 30
paths to the root