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ONTOLOGY REPORT - ANNOTATIONS

Term:cell fate commitment involved in pattern specification
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Accession:GO:0060581 term browser browse the term
Definition:The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type.


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smoothened signaling pathway involved in ventral spinal cord interneuron specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:95729 (PMID:15215207) RGD PMID:15215207 NCBI chr13:29,946,882...30,163,589
Ensembl chr13:29,946,809...30,163,574 		JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO MGI:95728 (PMID:15215207) RGD PMID:15215207 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712 		JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling acts_upstream_of_or_within ISO MGI:4840420 (PMID:19684112) RGD PMID:19684112 NCBI chr 1:245,257,725...245,355,576
Ensembl chr 1:245,257,768...245,355,577 		JBrowse link
ventral spinal cord interneuron fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl1 achaete-scute family bHLH transcription factor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:16020526)		 UniProt
RGD		 PMID:16020526 GO_REF:0000024 NCBI chr 7:21,903,136...21,906,003
Ensembl chr 7:21,903,126...21,905,993 		JBrowse link
G Dll4 delta like canonical Notch ligand 4 involved_in ISO
IEA		 UniProtKB:Q8K3Q3 (PMID:17728344)
GO_REF:0000107		 RGD
Ensembl		 PMID:17728344 GO_REF:0000107 NCBI chr 3:106,317,114...106,327,004
Ensembl chr 3:106,316,986...106,326,931 		JBrowse link
G Foxn4 forkhead box N4 involved_in ISO (PMID:16020526), (PMID:17728344) RGD PMID:16020526 PMID:17728344 NCBI chr12:42,336,706...42,359,932
Ensembl chr12:42,340,323...42,359,921 		JBrowse link
ventral spinal cord interneuron fate determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx2-2 NK2 homeobox 2 acts_upstream_of_or_within ISO MGI:1932100 (PMID:10217145) RGD PMID:10217145 NCBI chr 3:134,619,701...134,630,282
Ensembl chr 3:134,620,039...134,622,411 		JBrowse link
ventral spinal cord interneuron specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbx1 developing brain homeobox 1 acts_upstream_of_or_within ISO MGI:2182329 (PMID:11239429) RGD PMID:11239429 NCBI chr 1:99,348,638...99,354,173
Ensembl chr 1:99,349,608...99,354,038 		JBrowse link
G Dmrt3 doublesex and mab-3 related transcription factor 3 acts_upstream_of_or_within ISO MGI:4420993 (PMID:22932389) RGD PMID:22932389 NCBI chr 1:223,244,340...223,264,254
Ensembl chr 1:223,248,747...223,262,530 		JBrowse link
G Lhx3 LIM homeobox 3 acts_upstream_of_or_within ISO (PMID:19666821) RGD PMID:19666821 NCBI chr 3:9,026,432...9,035,122
Ensembl chr 3:9,027,425...9,034,480 		JBrowse link
G Shh sonic hedgehog signaling molecule acts_upstream_of_or_within IDA PMID:9230312 MGI PMID:9230312 RGD:8553789 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Sox1 SRY-box transcription factor 1 acts_upstream_of_or_within ISO MGI:3653406 (PMID:20844123) RGD PMID:20844123 NCBI chr16:77,135,577...77,139,592
Ensembl chr16:77,137,584...77,138,762 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20069
    multicellular organismal process 8906
      pattern specification process 500
        cell fate commitment involved in pattern specification 12
          cell fate determination involved in pattern specification + 1
          cell fate specification involved in pattern specification + 8
          dorsal vessel aortic cell fate commitment 0
          dorsal vessel heart proper cell fate commitment 0
          eye field cell fate commitment involved in camera-type eye formation 0
          ventral spinal cord interneuron fate commitment + 12
Path 2
Term Annotations click to browse term
  biological_process 20069
    cellular process 19150
      cellular developmental process 4781
        cell differentiation 4780
          cell fate commitment 296
            cell fate commitment involved in pattern specification 12
              cell fate determination involved in pattern specification + 1
              cell fate specification involved in pattern specification + 8
              dorsal vessel aortic cell fate commitment 0
              dorsal vessel heart proper cell fate commitment 0
              eye field cell fate commitment involved in camera-type eye formation 0
              ventral spinal cord interneuron fate commitment + 12
paths to the root