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ONTOLOGY REPORT - ANNOTATIONS


Term:cell fate commitment involved in pattern specification
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Accession:GO:0060581 term browser browse the term
Definition:The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type.


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smoothened signaling pathway involved in ventral spinal cord interneuron specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI family zinc finger 2 ISO MGI:95729 (MGI:3051712|PMID:15215207) RGD PMID:15215207 MGI:3051712 NCBI chr13:34,829,021...35,049,172
Ensembl chr13:34,829,139...35,048,444
JBrowse link
G Gli3 GLI family zinc finger 3 ISO MGI:95728 (MGI:3051712|PMID:15215207) RGD PMID:15215207 MGI:3051712 NCBI chr17:52,294,942...52,569,036
Ensembl chr17:52,294,942...52,569,036
JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling ISO MGI:4840420 (MGI:4355593|PMID:19684112) RGD PMID:19684112 MGI:4355593 NCBI chr 1:266,143,766...266,241,742
Ensembl chr 1:266,143,818...266,239,016
JBrowse link
ventral spinal cord interneuron fate commitment term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl1 achaete-scute family bHLH transcription factor 1 ISS
ISO
GO_REF:0000024
(MGI:3587461|PMID:16020526)
UniProt
RGD
PMID:16020526 GO_REF:0000024, MGI:3587461 NCBI chr 7:28,038,662...28,040,504
Ensembl chr 7:28,038,662...28,040,510
JBrowse link
G Dll4 delta like canonical Notch ligand 4 ISO UniProtKB:Q8K3Q3 (PMID:17728344) RGD PMID:17728344 NCBI chr 3:111,135,011...111,146,746
Ensembl chr 3:111,135,021...111,145,986
JBrowse link
G Foxn4 forkhead box N4 ISO (MGI:3587461|PMID:16020526), (MGI:3765356|PMID:17728344) RGD PMID:16020526, PMID:17728344 MGI:3587461, MGI:3765356 NCBI chr12:48,101,012...48,121,281
Ensembl chr12:48,101,673...48,121,270
JBrowse link
ventral spinal cord interneuron fate determination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx2-2 NK2 homeobox 2 ISO MGI:1932100 (MGI:1334824|PMID:10217145) RGD PMID:10217145 MGI:1334824 NCBI chr 3:141,408,460...141,419,083
Ensembl chr 3:141,408,798...141,411,170
JBrowse link
ventral spinal cord interneuron specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbx1 developing brain homeobox 1 ISO MGI:2182329 (MGI:2136554|PMID:11239429) RGD PMID:11239429 MGI:2136554 NCBI chr 1:104,969,218...104,973,648
Ensembl chr 1:104,969,218...104,973,648
JBrowse link
G Dmrt3 doublesex and mab-3 related transcription factor 3 ISO MGI:4420993 (MGI:5435948|PMID:22932389) RGD PMID:22932389 MGI:5435948 NCBI chr 1:243,589,607...243,602,926
Ensembl chr 1:243,589,607...243,602,926
JBrowse link
G Lhx3 LIM homeobox 3 ISO (MGI:4356383|PMID:19666821) RGD PMID:19666821 MGI:4356383 NCBI chr 3:3,653,861...3,662,509
Ensembl chr 3:3,654,755...3,661,810
JBrowse link
G Shh sonic hedgehog signaling molecule IDA PMID:9230312 MGI PMID:9230312 RGD:8553789 NCBI chr 4:718,538...727,691
Ensembl chr 4:718,538...727,691
JBrowse link
G Sox1 SRY-box transcription factor 1 ISO MGI:3653406 (MGI:4834949|PMID:20844123) RGD PMID:20844123 MGI:4834949

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    multicellular organismal process 9047
      pattern specification process 493
        cell fate commitment involved in pattern specification 12
          cell fate determination involved in pattern specification + 1
          cell fate specification involved in pattern specification + 8
          dorsal vessel aortic cell fate commitment 0
          dorsal vessel heart proper cell fate commitment 0
          eye field cell fate commitment involved in camera-type eye formation 0
          ventral spinal cord interneuron fate commitment + 12
Path 2
Term Annotations click to browse term
  biological_process 20020
    cellular process 18792
      cellular developmental process 4457
        cell differentiation 4362
          cell fate commitment 282
            cell fate commitment involved in pattern specification 12
              cell fate determination involved in pattern specification + 1
              cell fate specification involved in pattern specification + 8
              dorsal vessel aortic cell fate commitment 0
              dorsal vessel heart proper cell fate commitment 0
              eye field cell fate commitment involved in camera-type eye formation 0
              ventral spinal cord interneuron fate commitment + 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.