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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of calcidiol 1-monooxygenase activity
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Accession:GO:0060558 term browser browse the term
Definition:Any process that modulates the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O.


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regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vdr vitamin D receptor involved_in IEA
ISO		 GO_REF:0000107
(MGI:1097206|PMID:9295274)		 Ensembl
RGD		 PMID:9295274 GO_REF:0000107 MGI:1097206 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677 		JBrowse link
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 involved_in ISO
IEA		 (PMID:16549446)
GO_REF:0000107		 RGD
Ensembl		 PMID:16549446 GO_REF:0000107 NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241 		JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor involved_in ISO (PMID:15947108) RGD PMID:15947108 NCBI chr14:2,040,576...2,056,874
Ensembl chr14:2,042,434...2,051,814 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 involved_in ISO (PMID:15243130) RGD PMID:15243130 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
positive regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma involved_in ISO (PMID:9282826) RGD PMID:9282826 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO (PMID:16720713), (PMID:17023519) RGD PMID:16720713 PMID:17023519 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:1690216) RGD PMID:1690216 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19898
    biological regulation 13573
      regulation of molecular function 2736
        regulation of catalytic activity 1903
          regulation of oxidoreductase activity 114
            regulation of monooxygenase activity 57
              regulation of calcidiol 1-monooxygenase activity 7
                negative regulation of calcidiol 1-monooxygenase activity 3
                positive regulation of calcidiol 1-monooxygenase activity 3
paths to the root