Any process that decreases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.
Synonyms:
exact_synonym:
negative regulation of Rad51-mediated strand invasion
related_synonym:
negative regulation of D-loop biosynthesis; negative regulation of D-loop formation