muscle tissue development - Ontology Report

GO_REF:0000107

NCBI chr 3:116,591,271...116,617,382
Ensembl chr 3:123,503,899...123,529,919

SRPK3

SRSF protein kinase 3

involved_in

GO_REF:0000107

NCBI chr X:143,331,213...143,336,426
Ensembl chr X:153,216,794...153,222,273

aorta smooth muscle tissue morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

COL3A1

collagen type III alpha 1 chain

involved_in

(MGI:5307011|PMID:21071432)

PMID:21071432

MGI:5307011

NCBI chr2B:76,285,115...76,322,703
Ensembl chr2B:194,204,613...194,242,956

EFEMP2

EGF containing fibulin extracellular matrix protein 2

involved_in

(MGI:5660411|PMID:26178373), (MGI:6158865|PMID:26711913)

PMID:26178373 PMID:26711913

MGI:5660411 MGI:6158865

NCBI chr11:61,226,755...61,233,181
Ensembl chr11:64,555,877...64,561,950

MYLK

myosin light chain kinase

involved_in

GO_REF:0000107

NCBI chr 3:120,711,705...120,983,432
Ensembl chr 3:127,614,173...127,793,261

PROX1

prospero homeobox 1

involved_in

GO_REF:0000107

NCBI chr 1:189,556,124...189,609,297
Ensembl chr 1:194,412,980...194,460,763

atrial cardiac muscle cell development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

FHL2

four and a half LIM domains 2

acts_upstream_of_or_within
involved_in

(PMID:15509787)

PMID:15509787

GO_REF:0000107

NCBI chr2A:96,391,513...96,469,267
Ensembl chr2A:106,446,368...106,484,895

NKX2-6

NK2 homeobox 6

acts_upstream_of_or_within
involved_in

(PMID:9621431)

PMID:9621431

GO_REF:0000107

NCBI chr 8:22,949,843...22,955,391
Ensembl chr 8:19,884,480...19,888,643

atrial cardiac muscle tissue development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

EDNRA

endothelin receptor type A

involved_in

GO_REF:0000107

NCBI chr 4:139,815,336...139,879,600
Ensembl chr 4:151,476,356...151,536,497

NK2 homeobox 5

involved_in

GO_REF:0000107

NCBI chr 5:168,584,197...168,589,406
Ensembl chr 5:175,492,288...175,495,514

TREX1

three prime repair exonuclease 1

acts_upstream_of_or_within
involved_in

(MGI:3052278|PMID:15254239)

PMID:15254239

GO_REF:0000107 MGI:3052278

NCBI chr 3:48,387,762...48,389,693
Ensembl chr 3:49,470,222...49,471,331

ZIC3

Zic family member 3

involved_in

GO_REF:0000107

NCBI chr X:126,691,534...126,705,788
Ensembl chr X:136,954,024...136,967,819

atrial cardiac muscle tissue morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BMP10

bone morphogenetic protein 10

acts_upstream_of_or_within
involved_in

(PMID:10072785)

PMID:10072785

GO_REF:0000107

NCBI chr2A:68,901,944...68,912,559
Ensembl chr2A:70,023,655...70,034,420

ENG

endoglin

involved_in

GO_REF:0000107

NCBI chr 9:98,934,080...98,973,862
Ensembl chr 9:127,605,608...127,644,641

MYH6

myosin heavy chain 6

involved_in

GO_REF:0000107

NCBI chr14:4,200,616...4,226,193
Ensembl chr14:22,294,965...22,321,331

NOG

noggin

involved_in

GO_REF:0000107

NCBI chr17:50,669,186...50,671,081
Ensembl chr17:55,532,394...55,533,092

paired like homeodomain 2

acts_upstream_of_or_within

(MGI:2135655|PMID:11493526)

PMID:11493526

MGI:2135655

NCBI chr 4:103,112,624...103,137,356

PROX1

prospero homeobox 1

involved_in

GO_REF:0000107

NCBI chr 1:189,556,124...189,609,297
Ensembl chr 1:194,412,980...194,460,763

TNNT2

troponin T2, cardiac type

acts_upstream_of_or_within

(MGI:1342889|PMID:10449439)

PMID:10449439

MGI:1342889

NCBI chr 1:176,957,298...176,976,033

WNT2

Wnt family member 2

acts_upstream_of_or_within
involved_in

(MGI:4439199|PMID:20159597)

PMID:20159597

GO_REF:0000107 MGI:4439199

NCBI chr 7:109,244,772...109,291,472
Ensembl chr 7:121,936,031...121,985,862

atrioventricular bundle cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

IRX3

iroquois homeobox 3

involved_in

GO_REF:0000107

NCBI chr16:34,514,107...34,517,576
Ensembl chr16:53,622,409...53,624,653

T-box transcription factor 3

acts_upstream_of_or_within
involved_in

(MGI:3847383|PMID:18467625)

PMID:18467625

GO_REF:0000107 MGI:3847383

NCBI chr12:112,240,050...112,254,299
Ensembl chr12:115,620,002...115,631,316

T-box transcription factor 5

involved_in

GO_REF:0000107

NCBI chr12:111,954,222...112,009,261
Ensembl chr12:115,333,609...115,389,739

atrioventricular node cell development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

bone morphogenetic protein receptor type 1A

involved_in

GO_REF:0000107

NCBI chr10:83,185,040...83,353,239
Ensembl chr10:86,837,469...86,912,912

MAML1

mastermind like transcriptional coactivator 1

involved_in

GO_REF:0000107

NCBI chr 5:174,886,694...174,931,153
Ensembl chr 5:182,230,351...182,242,296

NK2 homeobox 5

acts_upstream_of_or_within
involved_in

(MGI:4355491|PMID:19546853)

PMID:19546853

GO_REF:0000107 MGI:4355491

NCBI chr 5:168,584,197...168,589,406
Ensembl chr 5:175,492,288...175,495,514

T-box transcription factor 5

involved_in

GO_REF:0000107

NCBI chr12:111,954,222...112,009,261
Ensembl chr12:115,333,609...115,389,739

atrioventricular node cell fate commitment

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

NK2 homeobox 5

acts_upstream_of_or_within
involved_in

(MGI:3040116|PMID:15109497)

PMID:15109497

GO_REF:0000107 MGI:3040116

NCBI chr 5:168,584,197...168,589,406
Ensembl chr 5:175,492,288...175,495,514

T-box transcription factor 5

involved_in

GO_REF:0000107

NCBI chr12:111,954,222...112,009,261
Ensembl chr12:115,333,609...115,389,739

atrioventricular node development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

NK2 homeobox 5

involved_in

GO_REF:0000107

NCBI chr 5:168,584,197...168,589,406
Ensembl chr 5:175,492,288...175,495,514

notch receptor 1

involved_in

GO_REF:0000107

NCBI chr 9:107,568,670...107,621,032
Ensembl chr 9:136,544,639...136,598,740

branchiomeric skeletal muscle development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

MSC

musculin

involved_in

(MGI:3653784|PMID:12493912)

PMID:12493912

MGI:3653784

NCBI chr 8:68,365,708...68,368,628

PITX1

paired like homeodomain 1

acts_upstream_of_or_within
involved_in

(MGI:3706272|PMID:17384148)

PMID:17384148

GO_REF:0000107 MGI:3706272

NCBI chr 5:130,422,920...130,429,828
Ensembl chr 5:136,565,285...136,570,350

TCF21

transcription factor 21

involved_in

GO_REF:0000107

NCBI chr 6:131,656,582...131,662,983
Ensembl chr 6:135,754,896...135,761,294

bundle of His development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ID2

inhibitor of DNA binding 2

acts_upstream_of_or_within

(MGI:3716040|PMID:17604724)

PMID:17604724

MGI:3716040

NCBI chr2A:8,681,592...8,684,014
Ensembl chr2A:8,847,776...8,850,720

NK2 homeobox 5

acts_upstream_of_or_within
involved_in

(MGI:3716040|PMID:17604724)

PMID:17604724

GO_REF:0000107 MGI:3716040

NCBI chr 5:168,584,197...168,589,406
Ensembl chr 5:175,492,288...175,495,514

T-box transcription factor 5

acts_upstream_of_or_within
involved_in

(MGI:3716040|PMID:17604724)

PMID:17604724

GO_REF:0000107 MGI:3716040

NCBI chr12:111,954,222...112,009,261
Ensembl chr12:115,333,609...115,389,739

canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Wnt family member 3A

involved_in

GO_REF:0000107

NCBI chr 1:203,409,294...203,463,214
Ensembl chr 1:208,628,706...208,674,469

WNT8A

Wnt family member 8A

involved_in

(PMID:20559569)

PMID:20559569

NCBI chr 5:133,419,324...133,471,094
Ensembl chr 5:139,598,229...139,605,926

cardiac conduction system development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

bone morphogenetic protein receptor type 1A

involved_in

GO_REF:0000107

NCBI chr10:83,185,040...83,353,239
Ensembl chr10:86,837,469...86,912,912

CDC42

cell division cycle 42

acts_upstream_of_or_within

(MGI:5052204|PMID:21690310)

PMID:21690310

MGI:5052204

NCBI chr 1:21,245,970...21,286,210

GJA5

gap junction protein alpha 5

acts_upstream_of_or_within

(MGI:5304955|PMID:22203979)
(MGI:4412358|PMID:18599871)

PMID:18599871 PMID:22203979

MGI:4412358 MGI:5304955

NCBI chr 1:123,200,111...123,224,626
Ensembl chr 1:112,328,337...112,329,413

NK2 homeobox 5

acts_upstream_of_or_within
involved_in

(MGI:5052204|PMID:21690310)
(PMID:15109497)

PMID:15109497 PMID:21690310

GO_REF:0000107 MGI:5052204

NCBI chr 5:168,584,197...168,589,406
Ensembl chr 5:175,492,288...175,495,514

neuregulin 1

acts_upstream_of_or_within
involved_in

(MGI:2384269|PMID:12149465)

PMID:12149465

GO_REF:0000107 MGI:2384269

NCBI chr 8:30,954,852...32,084,411
Ensembl chr 8:29,050,222...29,263,977

cardiac muscle cell development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACTN2

actinin alpha 2

involved_in

GO_REF:0000107

NCBI chr 1:212,245,742...212,323,387
Ensembl chr 1:217,272,597...217,321,103

ALPK2

alpha kinase 2

involved_in

(PMID:29888752)

PMID:29888752

NCBI chr18:51,872,394...52,020,137

ALPK3

alpha kinase 3

acts_upstream_of_or_within

(MGI:5644402|PMID:21441111)

PMID:21441111

MGI:5644402

NCBI chr15:63,484,027...63,541,021

ASB2

ankyrin repeat and SOCS box containing 2

involved_in

GO_REF:0000107

NCBI chr14:74,566,607...74,608,905
Ensembl chr14:93,900,914...93,930,527

ATG7

autophagy related 7

acts_upstream_of_or_within

(MGI:3711608|PMID:17450150)

PMID:17450150

MGI:3711608

NCBI chr 3:11,208,600...11,488,757
Ensembl chr 3:11,554,100...11,833,398

CAV3

caveolin 3

acts_upstream_of_or_within
involved_in

(MGI:3849772|PMID:19535499)

PMID:19535499

GO_REF:0000107 MGI:3849772

NCBI chr 3:8,684,829...8,697,731
Ensembl chr 3:8,928,069...8,940,942

CXADR

CXADR Ig-like cell adhesion molecule

acts_upstream_of_or_within
involved_in

(MGI:3587448|PMID:16079292)

PMID:16079292

GO_REF:0000107 MGI:3587448

NCBI chr21:4,246,779...4,367,369
Ensembl chr21:17,636,952...17,693,324

DICER1

dicer 1, ribonuclease III

acts_upstream_of_or_within

(MGI:3774881|PMID:18256189)

PMID:18256189

MGI:3774881

NCBI chr14:75,709,029...75,780,779
Ensembl chr14:95,036,385...95,107,940

HDAC2

histone deacetylase 2

acts_upstream_of_or_within

(MGI:3711360|PMID:17322895)

PMID:17322895

MGI:3711360

NCBI chr 6:111,731,139...111,761,826
Ensembl chr 6:115,802,367...115,833,004

HNRNPU

heterogeneous nuclear ribonucleoprotein U

involved_in
acts_upstream_of_or_within

(MGI:5648096|PMID:26039991)

PMID:26039991

GO_REF:0000107 MGI:5648096

NCBI chr 1:220,450,218...220,461,412
Ensembl chr 1:225,817,899...225,842,031

LRRC10

leucine rich repeat containing 10

acts_upstream_of_or_within
involved_in

(MGI:5484795|PMID:23236519)

PMID:23236519

GO_REF:0000107 MGI:5484795

NCBI chr12:67,135,114...67,137,929
Ensembl chr12:69,907,049...69,907,882

MET

MET proto-oncogene, receptor tyrosine kinase

acts_upstream_of_or_within

(MGI:5529574|PMID:23994610)

PMID:23994610

MGI:5529574

NCBI chr 7:108,646,278...108,772,238
Ensembl chr 7:121,365,438...121,468,159

MTOR

mechanistic target of rapamycin kinase

acts_upstream_of_or_within
involved_in

(MGI:5632243|PMID:25139234)

PMID:25139234

GO_REF:0000107 MGI:5632243

NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841

MYH11

myosin heavy chain 11

involved_in

GO_REF:0000107

Ensembl chr16:16,007,168...16,091,058

MYH6

myosin heavy chain 6

acts_upstream_of_or_within
involved_in

(MGI:3526615|PMID:15001446)
(MGI:1327483|PMID:9884344), (MGI:1333559|PMID:10066683)
(MGI:83539|PMID:8878443)

PMID:8878443 PMID:9884344 PMID:10066683 PMID:15001446

GO_REF:0000107 MGI:1327483 MGI:1333559 MGI:3526615 MGI:83539

NCBI chr14:4,200,616...4,226,193
Ensembl chr14:22,294,965...22,321,331

MYO18B

myosin XVIIIB

acts_upstream_of_or_within
involved_in

(MGI:3821523|PMID:18761673)

PMID:18761673

GO_REF:0000107 MGI:3821523

NCBI chr22:6,802,390...7,118,996
Ensembl chr22:24,529,348...24,816,779

NK2 homeobox 5

involved_in

GO_REF:0000107

NCBI chr 5:168,584,197...168,589,406
Ensembl chr 5:175,492,288...175,495,514

PLEC

plectin

involved_in

GO_REF:0000107

NCBI chr 8:140,681,252...140,742,753
Ensembl chr 8:143,674,696...143,712,433

SGCB

sarcoglycan beta

acts_upstream_of_or_within
involved_in

(MGI:1352919|PMID:10678176)

PMID:10678176

GO_REF:0000107 MGI:1352919

NCBI chr 4:71,924,051...71,942,642
Ensembl chr 4:78,476,969...78,491,156

SGCD

sarcoglycan delta

acts_upstream_of_or_within

(MGI:5790783|PMID:23695275)

PMID:23695275

MGI:5790783

NCBI chr 5:151,131,909...152,164,077
Ensembl chr 5:157,719,540...158,139,633

SLC8A1

solute carrier family 8 member A1

involved_in
acts_upstream_of_or_within

PMID:10967099 PMID:21302256

(MGI:1927695|PMID:10967099)
(MGI:4867054|PMID:21302256)

BHF-UCL
MGI

MGI:1927695 MGI:4867054

NCBI chr2A:40,169,339...40,586,546
Ensembl chr2A:40,939,900...41,363,038

SPEG

striated muscle enriched protein kinase

acts_upstream_of_or_within

(MGI:4830240|PMID:19118250)

PMID:19118250

MGI:4830240

NCBI chr2B:106,692,222...106,750,922
Ensembl chr2B:225,282,676...225,339,910

TCAP

titin-cap

involved_in

GO_REF:0000107

NCBI chr17:17,622,318...17,625,252
Ensembl chr17:17,839,139...17,842,727

TTN

titin

involved_in

(PMID:9817758)

PMID:9817758

NCBI chr2B:65,783,512...66,064,618

VEGFA

vascular endothelial growth factor A

acts_upstream_of_or_within

(MGI:1339868|PMID:10229225)

PMID:10229225

MGI:1339868

NCBI chr 6:43,361,053...43,377,366
Ensembl chr 6:44,650,365...44,666,353

XIRP1

xin actin binding repeat containing 1

acts_upstream_of_or_within

(MGI:3775114|PMID:17766470)

PMID:17766470

MGI:3775114

NCBI chr 3:39,079,712...39,089,098

ZMPSTE24

zinc metallopeptidase STE24

acts_upstream_of_or_within
involved_in

(MGI:2178865|PMID:11923874)

PMID:11923874

GO_REF:0000107 MGI:2178865

NCBI chr 1:39,545,264...39,589,721
Ensembl chr 1:40,869,076...40,912,747

cardiac muscle cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACADM

acyl-CoA dehydrogenase medium chain

acts_upstream_of_or_within
involved_in

(MGI:3692159|PMID:16121256)

PMID:16121256

GO_REF:0000107 MGI:3692159

NCBI chr 1:74,939,477...74,978,815
Ensembl chr 1:76,911,763...76,950,840

AKAP13

A-kinase anchoring protein 13

involved_in

(MGI:5308772|PMID:20139090)

PMID:20139090

MGI:5308772

NCBI chr15:64,076,422...64,438,109
Ensembl chr15:83,387,667...83,651,362

ALPK3

alpha kinase 3

involved_in

(MGI:2150538|PMID:11418590)

PMID:11418590

MGI:2150538

NCBI chr15:63,484,027...63,541,021

ARID1A

AT-rich interaction domain 1A

acts_upstream_of_or_within

(MGI:5578697|PMID:24335282)

PMID:24335282

MGI:5578697

NCBI chr 1:25,960,868...26,047,057
Ensembl chr 1:27,018,616...27,103,239

ASB2

ankyrin repeat and SOCS box containing 2

involved_in

GO_REF:0000107

NCBI chr14:74,566,607...74,608,905
Ensembl chr14:93,900,914...93,930,527

BMP2

bone morphogenetic protein 2

involved_in

GO_REF:0000107

NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610

BMP4

bone morphogenetic protein 4

involved_in

GO_REF:0000107

NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752

CACYBP

calcyclin binding protein

mRNA:increased expression:heart

RGD

PMID:16440310

RGD:2326117

NCBI chr 1:150,511,021...150,522,369
Ensembl chr 1:154,210,001...154,220,583

calreticulin

NCBI chr19:12,501,013...12,506,909
Ensembl chr19:13,242,900...13,249,416

CBY1

chibby family member 1, beta catenin antagonist

involved_in

(MGI:3768203|PMID:17261658)

PMID:17261658

MGI:3768203

NCBI chr22:19,571,658...19,588,872
Ensembl chr22:37,389,948...37,406,879

FOXP1

forkhead box P1

acts_upstream_of_or_within

(MGI:4829405|PMID:20713518)
(MGI:3056209|PMID:15342473)

PMID:15342473 PMID:20713518

MGI:3056209 MGI:4829405

NCBI chr 3:70,893,933...71,523,892
Ensembl chr 3:72,258,456...72,498,173

GATA binding protein 4

acts_upstream_of_or_within

PMID:16137232 PMID:18400219 PMID:20486789 PMID:20691899

(MGI:3790568|PMID:18400219)
(PMID:16137232)
(MGI:4881377|PMID:20691899)

RGD
MGI
BHF-UCL

MGI:3790568 MGI:4881377 RGD:5131636

NCBI chr 8:7,442,921...7,526,731

GATA binding protein 6

acts_upstream_of_or_within
involved_in

PMID:16137232 PMID:18400219

(PMID:16137232)
(MGI:3790568|PMID:18400219)

BHF-UCL
Ensembl
MGI

GO_REF:0000107 MGI:3790568

NCBI chr18:15,411,764...15,444,402

GREM1

gremlin 1, DAN family BMP antagonist

involved_in

(MGI:5315691|PMID:18545679)

PMID:18545679

MGI:5315691

NCBI chr15:11,213,870...11,230,619

IFT20

intraflagellar transport 20

acts_upstream_of_or_within
involved_in

(MGI:4361064|PMID:19654211)

PMID:19654211

GO_REF:0000107 MGI:4361064

NCBI chr17:28,438,960...28,446,113
Ensembl chr17:28,941,303...28,948,129

IFT88

intraflagellar transport 88

acts_upstream_of_or_within

(MGI:4361064|PMID:19654211)

PMID:19654211

MGI:4361064

NCBI chr13:1,893,102...2,017,771
Ensembl chr13:20,206,471...20,331,204

ITGB1

integrin subunit beta 1

acts_upstream_of_or_within

(MGI:84974|PMID:9004034)

PMID:9004034

MGI:84974

NCBI chr10:33,023,573...33,081,384
Ensembl chr10:33,608,978...33,644,031

KDM6B

lysine demethylase 6B

involved_in

GO_REF:0000107

NCBI chr17:7,878,783...7,889,372
Ensembl chr17:7,866,973...7,874,937

myocyte enhancer factor 2C

acts_upstream_of_or_within

(MGI:3820390|PMID:19035347)
(MGI:4881377|PMID:20691899)

PMID:19035347 PMID:20691899

MGI:3820390 MGI:4881377

NCBI chr 5:26,480,489...26,650,813
Ensembl chr 5:26,681,700...26,786,426

MESP1

mesoderm posterior bHLH transcription factor 1

involved_in

GO_REF:0000107

NCBI chr15:68,440,626...68,441,935
Ensembl chr15:87,645,768...87,647,210

MYOCD

myocardin

involved_in
acts_upstream_of_or_within

(MGI:2682181|PMID:14645532)

PMID:14645532

GO_REF:0000107 MGI:2682181

NCBI chr17:38,880,120...38,983,246
Ensembl chr17:43,584,259...43,681,659

NK2 homeobox 5

involved_in
acts_upstream_of_or_within

PMID:10021345 PMID:17234970 PMID:19035347 PMID:20486789

(MGI:3783941|PMID:17234970)
(MGI:3820390|PMID:19035347)
(MGI:1329801|PMID:10021345)

RGD
Ensembl
MGI

GO_REF:0000107 MGI:1329801 MGI:3783941 MGI:3820390 RGD:5131636

NCBI chr 5:168,584,197...168,589,406
Ensembl chr 5:175,492,288...175,495,514

NOX4

NADPH oxidase 4

acts_upstream_of_or_within

(MGI:3689176|PMID:16775014)

PMID:16775014

MGI:3689176

NCBI chr11:84,330,362...84,496,755

neuregulin 1

involved_in

(MGI:3701380|PMID:17336907)

NCBI chr 8:30,954,852...32,084,411
Ensembl chr 8:29,050,222...29,263,977

paired like homeodomain 2

acts_upstream_of_or_within

(MGI:3783941|PMID:17234970)
(MGI:2389284|PMID:12397115)

PMID:12397115 PMID:17234970

MGI:2389284 MGI:3783941

NCBI chr 4:103,112,624...103,137,356

SIK1

salt inducible kinase 1

involved_in

GO_REF:0000107

NCBI chr21:29,675,040...29,689,408

SIRT6

sirtuin 6

involved_in

(MGI:6284084|PMID:29555651)

PMID:29555651

MGI:6284084

NCBI chr19:3,196,092...3,204,602
Ensembl chr19:4,146,057...4,154,126

SLC9A1

solute carrier family 9 member A1

acts_upstream_of_or_within

(MGI:3837281|PMID:19011045)

PMID:19011045

MGI:3837281

NCBI chr 1:26,359,818...26,418,910
Ensembl chr 1:27,414,937...27,475,089

SOX6

SRY-box transcription factor 6

acts_upstream_of_or_within

(MGI:2678961|PMID:14530442)

PMID:14530442

MGI:2678961

NCBI chr11:16,053,730...16,488,566
Ensembl chr11:15,747,495...16,175,246

SYNE1

spectrin repeat containing nuclear envelope protein 1

NCBI chr 6:149,936,306...150,454,822
Ensembl chr 6:154,627,904...155,144,076

T-box transcription factor 3

acts_upstream_of_or_within
involved_in

(MGI:3783941|PMID:17234970)

PMID:17234970

GO_REF:0000107 MGI:3783941

NCBI chr12:112,240,050...112,254,299
Ensembl chr12:115,620,002...115,631,316

T-box transcription factor 5

involved_in
acts_upstream_of_or_within

(MGI:4881377|PMID:20691899)

PMID:20691899

GO_REF:0000107 MGI:4881377

NCBI chr12:111,954,222...112,009,261
Ensembl chr12:115,333,609...115,389,739

TDGF1

teratocarcinoma-derived growth factor 1

acts_upstream_of_or_within

(MGI:1321047|PMID:9876177)

PMID:9876177

MGI:1321047

NCBI chr 3:46,473,282...46,478,454
Ensembl chr 3:47,577,949...47,583,126

TIMM44

translocase of inner mitochondrial membrane 44

NCBI chr19:7,227,965...7,245,045
Ensembl chr19:8,081,069...8,100,479

TSC1

TSC complex subunit 1

acts_upstream_of_or_within
involved_in

(MGI:2137425|PMID:11438694)

PMID:11438694

GO_REF:0000107 MGI:2137425

NCBI chr 9:104,007,708...104,060,938
Ensembl chr 9:132,638,003...132,675,759

cardiac muscle cell fate commitment

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACVR1

activin A receptor type 1

involved_in

GO_REF:0000107

NCBI chr2B:44,994,175...45,133,490
Ensembl chr2B:162,234,823...162,297,805

T-box transcription factor 3

acts_upstream_of_or_within
involved_in

(MGI:3847383|PMID:18467625)

PMID:18467625

GO_REF:0000107 MGI:3847383

NCBI chr12:112,240,050...112,254,299
Ensembl chr12:115,620,002...115,631,316

Wnt family member 3A

acts_upstream_of_or_within
involved_in

(MGI:5295932|PMID:21554246)

PMID:21554246

GO_REF:0000107 MGI:5295932

NCBI chr 1:203,409,294...203,463,214
Ensembl chr 1:208,628,706...208,674,469

WT1

WT1 transcription factor

involved_in

(MGI:5285454|PMID:21654746)

PMID:21654746

MGI:5285454

NCBI chr11:32,349,807...32,398,494
Ensembl chr11:32,238,720...32,287,249

cardiac muscle cell proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABL1

ABL proto-oncogene 1, non-receptor tyrosine kinase

NCBI chr 9:101,834,189...102,005,811
Ensembl chr 9:130,484,333...130,652,941

ARID2

AT-rich interaction domain 2

acts_upstream_of_or_within
involved_in

(MGI:5649178|PMID:25299188)

PMID:25299188

GO_REF:0000107 MGI:5649178

NCBI chr12:42,823,236...43,004,465
Ensembl chr12:43,692,914...43,871,564

BMP10

bone morphogenetic protein 10

involved_in

GO_REF:0000107

NCBI chr2A:68,901,944...68,912,559
Ensembl chr2A:70,023,655...70,034,420

CSF1R

colony stimulating factor 1 receptor

NCBI chr 5:145,478,725...145,537,858
Ensembl chr 5:151,483,572...151,517,415

CXADR

CXADR Ig-like cell adhesion molecule

acts_upstream_of
involved_in

(MGI:3709954|PMID:16543498)

PMID:16543498

GO_REF:0000107 MGI:3709954

NCBI chr21:4,246,779...4,367,369
Ensembl chr21:17,636,952...17,693,324

DIPK2A

divergent protein kinase domain 2A

involved_in

GO_REF:0000107

NCBI chr 3:140,999,699...141,019,908
Ensembl chr 3:148,590,378...148,607,520

FES

FES proto-oncogene, tyrosine kinase

NCBI chr15:69,576,936...69,588,834
Ensembl chr15:88,774,965...88,786,965

FGF9

fibroblast growth factor 9

acts_upstream_of
involved_in

(MGI:3527351|PMID:15621532)
(MGI:3629544|PMID:16778080)

GO_REF:0000107 MGI:3527351 MGI:3629544

NCBI chr13:2,967,713...3,000,554
Ensembl chr13:21,273,333...21,307,198

FGFR1

fibroblast growth factor receptor 1

acts_upstream_of

(MGI:3629544|PMID:16778080)
(MGI:3527351|PMID:15621532)

MGI:3527351 MGI:3629544

NCBI chr 8:37,713,133...37,773,098
Ensembl chr 8:34,890,147...34,948,904

FGFR2

fibroblast growth factor receptor 2

acts_upstream_of

(MGI:3527351|PMID:15621532)
(MGI:3629544|PMID:16778080)

MGI:3527351 MGI:3629544

NCBI chr10:118,055,854...118,175,440
Ensembl chr10:121,469,735...121,588,815

FOXC1

forkhead box C1

acts_upstream_of_or_within

(MGI:3701735|PMID:16839542)

PMID:16839542

MGI:3701735

NCBI chr 6:1,429,051...1,433,180

FOXC2

forkhead box C2

acts_upstream_of_or_within

(MGI:3701735|PMID:16839542)

PMID:16839542

MGI:3701735

NCBI chr16:67,237,476...67,239,545

GATA binding protein 4

acts_upstream_of

(MGI:3833786|PMID:19084512)

MGI:3833786

NCBI chr 8:7,442,921...7,526,731

GATA binding protein 6

acts_upstream_of
involved_in

(MGI:3833786|PMID:19084512)

GO_REF:0000107 MGI:3833786

NCBI chr18:15,411,764...15,444,402

HDAC2

histone deacetylase 2

acts_upstream_of

(MGI:3711360|PMID:17322895)

PMID:17322895

MGI:3711360

NCBI chr 6:111,731,139...111,761,826
Ensembl chr 6:115,802,367...115,833,004

HEY2

hes related family bHLH transcription factor with YRPW motif 2

acts_upstream_of
involved_in

(MGI:3784153|PMID:17332425)

PMID:17332425

GO_REF:0000107 MGI:3784153

NCBI chr 6:123,527,180...123,538,794
Ensembl chr 6:127,647,547...127,659,056

JARID2

jumonji and AT-rich interaction domain containing 2

acts_upstream_of
involved_in

(MGI:3589998|PMID:15870077)

PMID:15870077

GO_REF:0000107 MGI:3589998

NCBI chr 6:15,100,415...15,376,505
Ensembl chr 6:15,466,050...15,739,170

KRAS

KRAS proto-oncogene, GTPase

NCBI chr12:61,062,689...61,108,524
Ensembl chr12:63,679,293...63,724,335

MAPK11

mitogen-activated protein kinase 11

acts_upstream_of
involved_in

(MGI:5288131|PMID:21768366)

GO_REF:0000107 MGI:5288131

NCBI chr22:30,492,664...30,499,456
Ensembl chr22:49,492,693...49,495,732

MYH10

myosin heavy chain 10

acts_upstream_of_or_within

(MGI:3052228|PMID:12893741)

PMID:12893741

MGI:3052228

NCBI chr17:43,023,922...43,180,159
Ensembl chr17:47,761,322...47,911,192

NK2 homeobox 5

acts_upstream_of_or_within
involved_in

(MGI:5429684|PMID:17350578)

PMID:17350578

GO_REF:0000107 MGI:5429684

NCBI chr 5:168,584,197...168,589,406
Ensembl chr 5:175,492,288...175,495,514

notch receptor 1

involved_in

GO_REF:0000107

NCBI chr 9:107,568,670...107,621,032
Ensembl chr 9:136,544,639...136,598,740

PRKAR1A

protein kinase cAMP-dependent type I regulatory subunit alpha

involved_in
acts_upstream_of_or_within

(MGI:3821563|PMID:18316483)

PMID:18316483

GO_REF:0000107 MGI:3821563

NCBI chr17:62,448,718...62,488,493
Ensembl chr17:67,838,484...67,877,943

RXRA

retinoid X receptor alpha

acts_upstream_of_or_within

(MGI:1101382|PMID:9428411)

PMID:9428411

MGI:1101382

NCBI chr 9:105,424,046...105,539,241
Ensembl chr 9:134,082,865...134,144,704

RXRB

retinoid X receptor beta

acts_upstream_of_or_within

(MGI:1101382|PMID:9428411)

PMID:9428411

MGI:1101382

NCBI chr 6:32,765,818...32,772,876
Ensembl chr 6:33,880,758...33,887,820

SAV1

salvador family WW domain containing protein 1

acts_upstream_of
involved_in

(MGI:4948149|PMID:21512031)

PMID:21512031

GO_REF:0000107 MGI:4948149

NCBI chr14:31,223,140...31,257,871
Ensembl chr14:49,525,687...49,560,347

SKI proto-oncogene

NCBI chr 1:944,428...1,029,695
Ensembl chr 1:2,091,620...2,174,080

SMAD1

SMAD family member 1

acts_upstream_of_or_within
involved_in

(MGI:5429684|PMID:17350578)

PMID:17350578

GO_REF:0000107 MGI:5429684

NCBI chr 4:137,822,269...137,899,700
Ensembl chr 4:149,481,836...149,558,135

T-box transcription factor 5

acts_upstream_of
involved_in

(MGI:3833786|PMID:19084512)

GO_REF:0000107 MGI:3833786

NCBI chr12:111,954,222...112,009,261
Ensembl chr12:115,333,609...115,389,739

TENM4

teneurin transmembrane protein 4

acts_upstream_of_or_within
involved_in

(MGI:5429684|PMID:17350578)

PMID:17350578

GO_REF:0000107 MGI:5429684

NCBI chr11:73,712,808...75,001,831
Ensembl chr11:77,338,422...77,743,909

TGFB2

transforming growth factor beta 2

involved_in

GO_REF:0000107

NCBI chr 1:193,907,398...194,005,800
Ensembl chr 1:198,758,751...198,859,041

TGFBR3

transforming growth factor beta receptor 3

involved_in

(MGI:2663364|PMID:12773577)

PMID:12773577

MGI:2663364

NCBI chr 1:94,337,275...94,539,229
Ensembl chr 1:93,080,452...93,285,587

WNT2

Wnt family member 2

acts_upstream_of
involved_in

(MGI:4439199|PMID:20159597)

PMID:20159597

GO_REF:0000107 MGI:4439199

NCBI chr 7:109,244,772...109,291,472
Ensembl chr 7:121,936,031...121,985,862

cardiac muscle thin filament assembly

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

NEBL

nebulette

involved_in

GO_REF:0000107

NCBI chr10:20,941,514...21,336,931
Ensembl chr10:21,244,693...21,632,236

cardiac muscle tissue development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ALDH1A2

aldehyde dehydrogenase 1 family member A2

acts_upstream_of_or_within
involved_in

(MGI:1328715|PMID:9892670)

PMID:9892670

GO_REF:0000107 MGI:1328715

NCBI chr15:36,925,443...37,038,288
Ensembl chr15:55,237,101...55,557,168

BMP5

bone morphogenetic protein 5

involved_in

(MGI:1332253|PMID:10079236)

PMID:10079236

MGI:1332253

NCBI chr 6:55,302,721...55,425,248
Ensembl chr 6:56,936,850...57,059,519

BMP7

bone morphogenetic protein 7

involved_in

GO_REF:0000107

NCBI chr20:53,509,484...53,606,889
Ensembl chr20:54,788,974...54,885,021

BMPR2

bone morphogenetic protein receptor type 2

NOT|involved_in

(MGI:3851675|PMID:19409885)

PMID:19409885

MGI:3851675

NCBI chr2B:89,631,622...89,823,438
Ensembl chr2B:207,780,741...207,961,072

CSRP3

cysteine and glycine rich protein 3

acts_upstream_of_or_within
involved_in

(MGI:1347184|PMID:10555147)

PMID:10555147

GO_REF:0000107 MGI:1347184

NCBI chr11:19,208,025...19,228,000
Ensembl chr11:19,121,234...19,140,820

GATA binding protein 4

acts_upstream_of_or_within

(MGI:5002493|PMID:20705924)

PMID:20705924

MGI:5002493

NCBI chr 8:7,442,921...7,526,731

GATA binding protein 6

acts_upstream_of_or_within
involved_in

(MGI:5002493|PMID:20705924)

PMID:20705924

GO_REF:0000107 MGI:5002493

NCBI chr18:15,411,764...15,444,402

GJC1

gap junction protein gamma 1

involved_in
acts_upstream_of_or_within

(MGI:3608436|PMID:14681043)

PMID:14681043

GO_REF:0000107 MGI:3608436

NCBI chr17:12,492,285...12,524,615
Ensembl chr17:12,689,251...12,690,441

HSPG2

heparan sulfate proteoglycan 2

acts_upstream_of_or_within

(MGI:1349497|PMID:10579729)

PMID:10579729

MGI:1349497

NCBI chr 1:21,014,951...21,129,937
Ensembl chr 1:21,979,504...22,053,400

ITGB1

integrin subunit beta 1

acts_upstream_of_or_within

(MGI:1203253|PMID:9553049)

PMID:9553049

MGI:1203253

NCBI chr10:33,023,573...33,081,384
Ensembl chr10:33,608,978...33,644,031

MRTFB

myocardin related transcription factor B

acts_upstream_of_or_within

(MGI:3695837|PMID:17183527)

PMID:17183527

MGI:3695837

NCBI chr16:12,999,165...13,195,012
Ensembl chr16:14,493,351...14,613,860

MTOR

mechanistic target of rapamycin kinase

acts_upstream_of_or_within
involved_in

(MGI:5632243|PMID:25139234)

PMID:25139234

GO_REF:0000107 MGI:5632243

NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841

NDUFV2

NADH:ubiquinone oxidoreductase core subunit V2

involved_in

(PMID:12754703)

PMID:12754703

NCBI chr18:5,154,158...5,186,088
Ensembl chr18:7,433,167...7,464,884

NK2 homeobox 5

acts_upstream_of_or_within
involved_in

(MGI:74918|PMID:7628699)

PMID:7628699

GO_REF:0000107 MGI:74918

NCBI chr 5:168,584,197...168,589,406
Ensembl chr 5:175,492,288...175,495,514

NPRL3

NPR3 like, GATOR1 complex subunit

acts_upstream_of_or_within
involved_in

(MGI:5319707|PMID:22538705)

PMID:22538705

GO_REF:0000107 MGI:5319707

Ensembl chr16:75,187...129,220

neuregulin 1

acts_upstream_of_or_within
involved_in

(MGI:5571433|PMID:24364879)

PMID:24364879

GO_REF:0000107 MGI:5571433

NCBI chr 8:30,954,852...32,084,411
Ensembl chr 8:29,050,222...29,263,977

paired like homeodomain 2

acts_upstream_of_or_within

(MGI:3701739|PMID:16836994)

PMID:16836994

MGI:3701739

NCBI chr 4:103,112,624...103,137,356

PLN

phospholamban

acts_upstream_of_or_within
involved_in

(MGI:1347184|PMID:10555147)

PMID:10555147

GO_REF:0000107 MGI:1347184

NCBI chr 6:116,357,335...116,370,382
Ensembl chr 6:120,509,510...120,509,668

PRMT1

protein arginine methyltransferase 1

involved_in

(MGI:6267004|PMID:30321814)

PMID:30321814

MGI:6267004

NCBI chr19:46,691,795...46,705,179
Ensembl chr19:55,610,938...55,623,135

PTEN

phosphatase and tensin homolog

acts_upstream_of_or_within

(MGI:3588627|PMID:16107612)

PMID:16107612

MGI:3588627

NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605

RBP4

retinol binding protein 4

involved_in

(MGI:2655947|PMID:12663486)

PMID:12663486

MGI:2655947

NCBI chr10:90,337,879...90,347,530
Ensembl chr10:93,848,166...93,857,887

SIN3B

SIN3 transcription regulator family member B

involved_in

(MGI:3687784|PMID:10620510)

PMID:10620510

MGI:3687784

NCBI chr19:16,317,329...16,367,320
Ensembl chr19:17,296,161...17,345,533

TAFAZZIN

tafazzin, phospholipid-lysophospholipid transacylase

involved_in

GO_REF:0000107

NCBI chr X:143,853,054...143,863,491
Ensembl chr X:153,725,294...153,734,046

TBX2

T-box transcription factor 2

acts_upstream_of_or_within
involved_in

(MGI:3487212|PMID:15459098)

PMID:15459098

GO_REF:0000107 MGI:3487212

NCBI chr17:55,501,932...55,511,537
Ensembl chr17:60,622,098...60,630,189

ZFPM2

zinc finger protein, FOG family member 2

acts_upstream_of_or_within
involved_in

(MGI:3586963|PMID:16103912)

PMID:16103912

GO_REF:0000107 MGI:3586963

NCBI chr 8:101,872,850...102,430,622
Ensembl chr 8:104,023,062...104,576,688

cardiac muscle tissue growth

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CCM2L

CCM2 like scaffold protein

acts_upstream_of_or_within

(MGI:5437815|PMID:22898778)

PMID:22898778

MGI:5437815

NCBI chr20:28,303,996...28,327,319

HEG1

heart development protein with EGF like domains 1

acts_upstream_of_or_within
involved_in

(MGI:5437815|PMID:22898778)

PMID:22898778

GO_REF:0000107 MGI:5437815

NCBI chr 3:122,091,832...122,204,436
Ensembl chr 3:128,969,817...129,028,317

cardiac muscle tissue growth involved in heart morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

S1PR1

sphingosine-1-phosphate receptor 1

involved_in

GO_REF:0000107

NCBI chr 1:103,893,199...103,898,381
Ensembl chr 1:102,608,839...102,609,987

cardiac muscle tissue morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ANKRD1

ankyrin repeat domain 1

involved_in

GO_REF:0000107

NCBI chr10:87,652,254...87,661,173
Ensembl chr10:91,180,034...91,188,165

BMP2

bone morphogenetic protein 2

acts_upstream_of_or_within
involved_in

(MGI:3611958|PMID:16314491)

PMID:16314491

GO_REF:0000107 MGI:3611958

NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610

EGLN1

egl-9 family hypoxia inducible factor 1

acts_upstream_of_or_within

(MGI:3689683|PMID:16966370)

PMID:16966370

MGI:3689683

NCBI chr 1:206,915,541...206,976,656

LOC100987752

actin alpha cardiac muscle 1

acts_upstream_of_or_within

(MGI:3606389|PMID:14605248)

PMID:14605248

MGI:3606389

NCBI chr15:13,707,475...13,712,905
Ensembl chr15:31,966,278...31,971,782

MYLK2

myosin light chain kinase 2

involved_in

GO_REF:0000107

NCBI chr20:28,113,024...28,128,142
Ensembl chr20:29,243,391...29,258,508

NK2 homeobox 5

involved_in

GO_REF:0000107

NCBI chr 5:168,584,197...168,589,406
Ensembl chr 5:175,492,288...175,495,514

notch receptor 1

involved_in

GO_REF:0000107

NCBI chr 9:107,568,670...107,621,032
Ensembl chr 9:136,544,639...136,598,740

TBX20

T-box transcription factor 20

involved_in

(MGI:3604925|PMID:15843409)

PMID:15843409

MGI:3604925

NCBI chr 7:35,855,969...35,878,533

TCAP

titin-cap

involved_in

GO_REF:0000107

NCBI chr17:17,622,318...17,625,252
Ensembl chr17:17,839,139...17,842,727

TTN

titin

involved_in
acts_upstream_of_or_within

PMID:9817758 PMID:17360664

(PMID:9817758)
(MGI:3760201|PMID:17360664)

BHF-UCL
MGI

MGI:3760201

NCBI chr2B:65,783,512...66,064,618

XIRP2

xin actin binding repeat containing 2

acts_upstream_of_or_within
involved_in

(MGI:4438861|PMID:20360251)

PMID:20360251

GO_REF:0000107 MGI:4438861

NCBI chr2B:54,445,543...54,516,773
Ensembl chr2B:171,642,482...171,989,732

ZFPM1

zinc finger protein, FOG family member 1

involved_in

(MGI:3583527|PMID:14614148)

PMID:14614148

MGI:3583527

NCBI chr16:69,164,299...69,246,136

cardiac myofibril assembly

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CSRP3

cysteine and glycine rich protein 3

involved_in

GO_REF:0000107

NCBI chr11:19,208,025...19,228,000
Ensembl chr11:19,121,234...19,140,820

FHOD3

formin homology 2 domain containing 3

acts_upstream_of_or_within
involved_in

(MGI:5436289|PMID:23213483)

PMID:23213483

GO_REF:0000107 MGI:5436289

NCBI chr18:29,550,049...30,033,130
Ensembl chr18:33,165,819...33,590,154

LOC100987752

actin alpha cardiac muscle 1

acts_upstream_of_or_within

(MGI:87509|PMID:9114002)

PMID:9114002

MGI:87509

NCBI chr15:13,707,475...13,712,905
Ensembl chr15:31,966,278...31,971,782

MYH10

myosin heavy chain 10

acts_upstream_of_or_within

(MGI:1099556|PMID:9356462)

PMID:9356462

MGI:1099556

NCBI chr17:43,023,922...43,180,159
Ensembl chr17:47,761,322...47,911,192

MYL2

myosin light chain 2

acts_upstream_of_or_within

(MGI:1194431|PMID:9422794)

PMID:9422794

MGI:1194431

NCBI chr12:108,479,941...108,489,739
Ensembl chr12:111,873,270...111,883,047

MYLK3

myosin light chain kinase 3

involved_in

PMID:17885681

NCBI chr16:26,966,653...27,029,413
Ensembl chr16:45,863,863...45,905,082

PDGFRA

platelet derived growth factor receptor alpha

involved_in

GO_REF:0000107

NCBI chr 4:69,639,081...69,709,870
Ensembl chr 4:76,199,382...76,271,097

PDGFRB

platelet derived growth factor receptor beta

involved_in

(MGI:1931346|PMID:11239463)

PMID:11239463

MGI:1931346

NCBI chr 5:145,538,330...145,580,312
Ensembl chr 5:151,543,891...151,585,530

SRF

serum response factor

acts_upstream_of_or_within
involved_in

(MGI:3513738|PMID:15569937)

PMID:15569937

GO_REF:0000107 MGI:3513738

NCBI chr 6:42,763,099...42,773,332
Ensembl chr 6:44,057,192...44,066,768

TCAP

titin-cap

involved_in

GO_REF:0000107

NCBI chr17:17,622,318...17,625,252
Ensembl chr17:17,839,139...17,842,727

TTN

titin

involved_in
acts_upstream_of_or_within

PMID:9817758 PMID:11846417 PMID:16702235

(PMID:11846417), (PMID:9817758)
(MGI:3653555|PMID:16702235)

BHF-UCL
MGI

MGI:3653555

NCBI chr2B:65,783,512...66,064,618

cardiac pacemaker cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

short stature homeobox 2

involved_in

GO_REF:0000107

NCBI chr 3:155,138,969...155,149,619
Ensembl chr 3:163,190,284...163,199,239

cell growth involved in cardiac muscle cell development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADRA1A

adrenoceptor alpha 1A

acts_upstream_of_or_within
involved_in

(MGI:2664013|PMID:12782680)

PMID:12782680

GO_REF:0000107 MGI:2664013

NCBI chr 8:25,947,996...26,138,022
Ensembl chr 8:22,853,677...23,044,388

ADRA1B

adrenoceptor alpha 1B

acts_upstream_of_or_within

(MGI:2664013|PMID:12782680)

PMID:12782680

MGI:2664013

NCBI chr 5:155,307,148...155,363,785
Ensembl chr 5:161,923,895...161,979,461

angiotensinogen

NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044

AGTR2

angiotensin II receptor type 2

NCBI chr X:105,252,903...105,257,171
Ensembl chr X:115,671,594...115,672,685

AKAP13

A-kinase anchoring protein 13

NCBI chr15:64,076,422...64,438,109
Ensembl chr15:83,387,667...83,651,362

CAMK2D

calcium/calmodulin dependent protein kinase II delta

NCBI chr 4:105,957,773...106,271,887
Ensembl chr 4:116,523,850...116,835,387

GATA binding protein 4

NCBI chr 8:7,442,921...7,526,731

GSK3B

glycogen synthase kinase 3 beta

NCBI chr 3:116,943,205...117,215,001
Ensembl chr 3:123,861,379...124,126,771

MAP2K4

mitogen-activated protein kinase kinase 4

NCBI chr17:39,497,105...39,622,331
Ensembl chr17:44,248,857...44,359,909

myosin light chain 2

NCBI chr12:108,479,941...108,489,739
Ensembl chr12:111,873,270...111,883,047

myocardin

NCBI chr17:38,880,120...38,983,246
Ensembl chr17:43,584,259...43,681,659

NPPA

natriuretic peptide A

NCBI chr 1:10,608,025...10,610,287
Ensembl chr 1:11,825,072...11,827,373

NPPB

natriuretic peptide B

NCBI chr 1:10,621,416...10,622,960
Ensembl chr 1:11,838,518...11,839,995

PDLIM5

PDZ and LIM domain 5

involved_in

PMID:24743145

NCBI chr 4:86,814,136...87,030,605
Ensembl chr 4:97,486,566...97,702,060

PRKG1

protein kinase cGMP-dependent 1

NCBI chr10:47,642,312...48,935,188
Ensembl chr10:49,779,211...51,064,882

SORBS2

sorbin and SH3 domain containing 2

involved_in

PMID:24743145

NCBI chr 4:177,751,089...178,125,937
Ensembl chr 4:189,965,729...190,070,543

extraocular skeletal muscle development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CACNA1S

calcium voltage-gated channel subunit alpha1 S

acts_upstream_of_or_within
involved_in

(MGI:3613415|PMID:14618389)

PMID:14618389

GO_REF:0000107 MGI:3613415

NCBI chr 1:176,639,189...176,712,171
Ensembl chr 1:180,941,836...181,014,823

FOXL2

forkhead box L2

involved_in

(PMID:12630957)

PMID:12630957

NCBI chr 3:135,968,040...135,980,063

MYH15

myosin heavy chain 15

NCBI chr 3:105,498,196...105,635,979
Ensembl chr 3:112,432,417...112,586,559

myomesin 1

NCBI chr18:11,057,733...11,215,998
Ensembl chr18:13,368,052...13,523,834

myomesin 2

NCBI chr 8:5,189,688...5,319,538
Ensembl chr 8:1,924,661...2,057,695

paired like homeodomain 2

acts_upstream_of_or_within

(MGI:4881620|PMID:21035439)
(MGI:3624183|PMID:16638982)

PMID:16638982 PMID:21035439

MGI:3624183 MGI:4881620

NCBI chr 4:103,112,624...103,137,356

His-Purkinje system cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

IRX3

iroquois homeobox 3

involved_in

GO_REF:0000107

NCBI chr16:34,514,107...34,517,576
Ensembl chr16:53,622,409...53,624,653

kidney smooth muscle cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

TSHZ3

teashirt zinc finger homeobox 3

involved_in

(MGI:3806378|PMID:18776146)

PMID:18776146

MGI:3806378

NCBI chr19:28,195,740...28,270,265
Ensembl chr19:36,946,685...37,021,531

left ventricular cardiac muscle tissue morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

EDNRA

endothelin receptor type A

involved_in

GO_REF:0000107

NCBI chr 4:139,815,336...139,879,600
Ensembl chr 4:151,476,356...151,536,497

RYR2

ryanodine receptor 2

acts_upstream_of_or_within

(MGI:3713015|PMID:17431507)

PMID:17431507

MGI:3713015

NCBI chr 1:212,600,198...213,387,312
Ensembl chr 1:217,815,676...218,383,509

SMAD4

SMAD family member 4

involved_in

GO_REF:0000107

NCBI chr18:44,402,112...44,456,779
Ensembl chr18:47,764,568...47,797,359

lung smooth muscle development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SOX9

SRY-box transcription factor 9

acts_upstream_of_or_within

(MGI:5524169|PMID:24218621)

PMID:24218621

MGI:5524169

NCBI chr17:66,028,737...66,034,122

SRF

serum response factor

acts_upstream_of_or_within
involved_in

(MGI:5524169|PMID:24218621)

PMID:24218621

GO_REF:0000107 MGI:5524169

NCBI chr 6:42,763,099...42,773,332
Ensembl chr 6:44,057,192...44,066,768

metanephric smooth muscle tissue development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

OSR1

odd-skipped related transcription factor 1

involved_in

GO_REF:0000107

NCBI chr2A:19,333,101...19,340,267
Ensembl chr2A:19,451,067...19,458,229

PKD2

polycystin 2, transient receptor potential cation channel

involved_in

GO_REF:0000107

NCBI chr 4:80,295,243...80,365,271
Ensembl chr 4:91,019,734...91,086,775

negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

DKK1

dickkopf WNT signaling pathway inhibitor 1

involved_in

GO_REF:0000107

NCBI chr10:48,950,704...48,953,815
Ensembl chr10:51,084,027...51,089,776

negative regulation of cardiac muscle cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BMP2

bone morphogenetic protein 2

involved_in

GO_REF:0000107

NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610

cyclin D2

NCBI chr12:4,385,957...4,417,602
Ensembl chr12:4,309,272...4,335,551

DKK1

dickkopf WNT signaling pathway inhibitor 1

involved_in

GO_REF:0000107

NCBI chr10:48,950,704...48,953,815
Ensembl chr10:51,084,027...51,089,776

DLL1

delta like canonical Notch ligand 1

involved_in

GO_REF:0000107

NCBI chr 6:168,440,192...168,449,071
Ensembl chr 6:173,534,292...173,544,759

FRS2

fibroblast growth factor receptor substrate 2

involved_in

GO_REF:0000107

NCBI chr12:66,992,207...67,107,313
Ensembl chr12:69,829,435...69,878,293

FZD7

frizzled class receptor 7

involved_in

GO_REF:0000107

NCBI chr2B:89,290,929...89,294,873
Ensembl chr2B:207,439,942...207,446,283

HDAC3

histone deacetylase 3

acts_upstream_of_or_within

(MGI:5571645|PMID:24565863)

PMID:24565863

MGI:5571645

NCBI chr 5:136,981,790...136,997,786
Ensembl chr 5:143,094,406...143,110,322

SOX6

SRY-box transcription factor 6

involved_in

GO_REF:0000107

NCBI chr11:16,053,730...16,488,566
Ensembl chr11:15,747,495...16,175,246

negative regulation of cardiac muscle cell proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

APC

APC regulator of WNT signaling pathway

involved_in

PMID:28948298

NCBI chr 5:108,070,697...108,208,273
Ensembl chr 5:113,904,352...114,009,709

CITED2

Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2

involved_in

PMID:26240138

NCBI chr 6:137,134,142...137,136,550

CXADR

CXADR Ig-like cell adhesion molecule

acts_upstream_of_or_within
involved_in

(MGI:3709954|PMID:16543498)

PMID:16543498

GO_REF:0000107 MGI:3709954

NCBI chr21:4,246,779...4,367,369
Ensembl chr21:17,636,952...17,693,324

GJA1

gap junction protein alpha 1

NCBI chr 6:119,213,513...119,227,617

HDAC2

histone deacetylase 2

acts_upstream_of_or_within

(MGI:3711360|PMID:17322895)

PMID:17322895

MGI:3711360

NCBI chr 6:111,731,139...111,761,826
Ensembl chr 6:115,802,367...115,833,004

JARID2

jumonji and AT-rich interaction domain containing 2

acts_upstream_of_or_within
involved_in

(MGI:3589998|PMID:15870077)

PMID:15870077

GO_REF:0000107 MGI:3589998

NCBI chr 6:15,100,415...15,376,505
Ensembl chr 6:15,466,050...15,739,170

KCNK2

potassium two pore domain channel subfamily K member 2

NCBI chr 1:190,576,180...190,807,367
Ensembl chr 1:195,430,994...195,662,840

MAPK11

mitogen-activated protein kinase 11

acts_upstream_of_or_within
involved_in

(MGI:5288131|PMID:21768366)

GO_REF:0000107 MGI:5288131

NCBI chr22:30,492,664...30,499,456
Ensembl chr22:49,492,693...49,495,732

NOG

noggin

involved_in

GO_REF:0000107

NCBI chr17:50,669,186...50,671,081
Ensembl chr17:55,532,394...55,533,092

PTEN

phosphatase and tensin homolog

involved_in

PMID:23575307 PMID:30783439

(MGI:5584062|PMID:23575307)

BHF-UCL
RGD

MGI:5584062 RGD:150527846

NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605

RBP4

retinol binding protein 4

involved_in

(MGI:2655947|PMID:12663486)

PMID:12663486

MGI:2655947

NCBI chr10:90,337,879...90,347,530
Ensembl chr10:93,848,166...93,857,887

SAV1

salvador family WW domain containing protein 1

involved_in
acts_upstream_of_or_within

(MGI:4948149|PMID:21512031)

PMID:21512031

GO_REF:0000107 MGI:4948149

NCBI chr14:31,223,140...31,257,871
Ensembl chr14:49,525,687...49,560,347

T-box transcription factor 5

involved_in

GO_REF:0000107

NCBI chr12:111,954,222...112,009,261
Ensembl chr12:115,333,609...115,389,739

TGFBR2

transforming growth factor beta receptor 2

NCBI chr 3:30,536,187...30,623,653
Ensembl chr 3:30,854,460...30,938,856

TP73

tumor protein p73

acts_upstream_of_or_within
involved_in

(PMID:18634800)

PMID:18634800

GO_REF:0000107

NCBI chr 1:2,323,399...2,405,295
Ensembl chr 1:3,476,064...3,529,206

VGLL4

vestigial like family member 4

involved_in

GO_REF:0000107

NCBI chr 3:11,489,805...11,654,507
Ensembl chr 3:11,834,746...11,981,877

negative regulation of cardiac muscle tissue development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

FGF3

fibroblast growth factor 3

involved_in

GO_REF:0000107

NCBI chr11:64,905,658...64,915,175
Ensembl chr11:68,197,962...68,207,042

FGF8

fibroblast growth factor 8

involved_in

GO_REF:0000107

NCBI chr10:98,372,251...98,378,811
Ensembl chr10:101,844,792...101,853,916

negative regulation of cardiac myofibril assembly

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SMAD4

SMAD family member 4

involved_in

GO_REF:0000107

NCBI chr18:44,402,112...44,456,779
Ensembl chr18:47,764,568...47,797,359

negative regulation of cell growth involved in cardiac muscle cell development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

caveolin 3

NCBI chr 3:8,684,829...8,697,731
Ensembl chr 3:8,928,069...8,940,942

CTDP1

CTD phosphatase subunit 1

NCBI chr18:73,279,510...73,357,718
Ensembl chr18:76,646,641...76,722,573

forkhead box P1

NCBI chr 3:70,893,933...71,523,892
Ensembl chr 3:72,258,456...72,498,173

G6PD

glucose-6-phosphate dehydrogenase

NCBI chr X:143,972,798...143,988,960
Ensembl chr X:153,843,092...153,860,674

GSK3A

glycogen synthase kinase 3 alpha

involved_in

GO_REF:0000107

NCBI chr19:39,118,330...39,130,768
Ensembl chr19:47,710,197...47,726,948

PAK1

p21 (RAC1) activated kinase 1

NCBI chr11:72,372,577...72,524,817
Ensembl chr11:76,015,998...76,104,197

PI16

peptidase inhibitor 16

acts_upstream_of_or_within
involved_in

(MGI:3810223|PMID:17909105)

PMID:17909105

GO_REF:0000107 MGI:3810223

NCBI chr 6:36,509,410...36,526,692
Ensembl chr 6:37,711,423...37,721,812

PPARA

peroxisome proliferator activated receptor alpha

Ensembl chr22:45,218,364...45,302,970

RBM10

RNA binding motif protein 10

NCBI chr X:39,582,480...39,623,749
Ensembl chr X:47,440,815...47,481,204

RGS2

regulator of G protein signaling 2

NCBI chr 1:168,273,112...168,276,348
Ensembl chr 1:172,566,701...172,569,955

RGS4

regulator of G protein signaling 4

NCBI chr 1:138,488,317...138,496,497
Ensembl chr 1:142,284,040...142,292,225

TOMM70

translocase of outer mitochondrial membrane 70

NCBI chr 3:97,459,180...97,497,175
Ensembl chr 3:104,139,473...104,178,074

YY1

YY1 transcription factor

NCBI chr14:80,859,491...80,903,651

ZNF416

zinc finger protein 416

acts_upstream_of_or_within

(MGI:5920524|PMID:29065170)

PMID:29065170

MGI:5920524

NCBI chr19:54,583,428...54,590,792
Ensembl chr19:63,412,869...63,420,231

negative regulation of kidney smooth muscle cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

sonic hedgehog signaling molecule

involved_in

GO_REF:0000107

NCBI chr 7:147,400,112...147,414,036
Ensembl chr 7:159,114,666...159,126,651

negative regulation of muscle tissue development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

FLCN

folliculin

involved_in

GO_REF:0000107

NCBI chr17:34,057,127...34,081,637
Ensembl chr17:38,988,518...39,013,160

IGFBP5

insulin like growth factor binding protein 5

involved_in

GO_REF:0000107

NCBI chr2B:103,932,983...103,956,475
Ensembl chr2B:222,534,967...222,558,432

negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

LRP6

LDL receptor related protein 6

acts_upstream_of_or_within

(MGI:4830282|PMID:19056682)

PMID:19056682

MGI:4830282

NCBI chr12:12,121,411...12,288,590
Ensembl chr12:12,508,108...12,657,973

negative regulation of satellite cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AKIRIN1

akirin 1

involved_in

GO_REF:0000107

NCBI chr 1:38,269,096...38,283,920
Ensembl chr 1:39,616,036...39,629,300

EPHB1

EPH receptor B1

involved_in

GO_REF:0000107

NCBI chr 3:131,841,459...132,309,082
Ensembl chr 3:139,313,387...139,776,802

MSTN

myostatin

involved_in

ISS

AgBase

GO_REF:0000024

NCBI chr2B:77,364,927...77,452,426
Ensembl chr2B:195,283,903...195,290,922

SIX4

SIX homeobox 4

involved_in

GO_REF:0000107

NCBI chr14:41,316,169...41,332,160
Ensembl chr14:59,580,587...59,594,014

negative regulation of skeletal muscle cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

LOC100984344

calpain-3

acts_upstream_of_or_within

(MGI:5476405|PMID:23300487)

PMID:23300487

MGI:5476405

NCBI chr15:21,227,371...21,372,406
Ensembl chr15:39,476,302...39,528,820

MYOCD

myocardin

involved_in

GO_REF:0000107

NCBI chr17:38,880,120...38,983,246
Ensembl chr17:43,584,259...43,681,659

S100B

S100 calcium binding protein B

NCBI chr21:33,063,845...33,070,073
Ensembl chr21:46,197,750...46,203,953

negative regulation of skeletal muscle tissue development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

NRAS

NRAS proto-oncogene, GTPase

acts_upstream_of_or_within

(MGI:4839883|PMID:20534588)

PMID:20534588

MGI:4839883

NCBI chr 1:87,837,146...87,850,013
Ensembl chr 1:122,890,505...122,903,585

QARS1

glutaminyl-tRNA synthetase 1

involved_in

GO_REF:0000107

NCBI chr 3:49,020,310...49,029,443
Ensembl chr 3:50,100,216...50,125,112

TGFB1

transforming growth factor beta 1

involved_in

(PMID:9770491)

PMID:9770491

NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973

TSC22D3

TSC22 domain family member 3

acts_upstream_of_or_within

(MGI:4838954|PMID:20124407)

PMID:20124407

MGI:4838954

NCBI chr X:96,806,179...96,870,020
Ensembl chr X:107,179,077...107,242,902

TWIST1

twist family bHLH transcription factor 1

acts_upstream_of_or_within

(MGI:69156|PMID:7958419), (MGI:76047|PMID:7664846)

PMID:7664846 PMID:7958419

MGI:69156 MGI:76047

NCBI chr 7:19,761,041...19,765,665

USP19

ubiquitin specific peptidase 19

involved_in

GO_REF:0000107

NCBI chr 3:49,032,373...49,045,238
Ensembl chr 3:50,100,216...50,125,112

USP2

ubiquitin specific peptidase 2

involved_in

PMID:10938131

NCBI chr11:114,196,725...114,223,411
Ensembl chr11:118,124,350...118,150,868

YBX3

Y-box binding protein 3

acts_upstream_of_or_within
involved_in

(MGI:3808638|PMID:18676817)

PMID:18676817

GO_REF:0000107 MGI:3808638

NCBI chr12:10,728,049...10,752,267
Ensembl chr12:10,996,380...11,018,172

negative regulation of skeletal muscle tissue growth

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

MSTN

myostatin

acts_upstream_of_or_within
involved_in

PMID:16575154 PMID:18286185

(MGI:3776975|PMID:18286185)

RGD
MGI
Ensembl

GO_REF:0000107 MGI:3776975 RGD:1601299

NCBI chr2B:77,364,927...77,452,426
Ensembl chr2B:195,283,903...195,290,922

TLL2

tolloid like 2

acts_upstream_of_or_within
involved_in

(MGI:3776975|PMID:18286185)

PMID:18286185

GO_REF:0000107 MGI:3776975

NCBI chr10:92,978,334...93,129,098
Ensembl chr10:96,483,401...96,633,281

negative regulation of striated muscle tissue development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BDNF

brain derived neurotrophic factor

NCBI chr11:27,618,322...27,687,661
Ensembl chr11:27,520,312...27,589,239

BMP4

bone morphogenetic protein 4

acts_upstream_of_or_within
involved_in

(PMID:14749725)

PMID:14749725

GO_REF:0000107

NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752

LEF1

lymphoid enhancer binding factor 1

acts_upstream_of_or_within
involved_in

(MGI:3656361|PMID:16936075)

PMID:16936075

GO_REF:0000107 MGI:3656361

NCBI chr 4:100,552,959...100,674,156
Ensembl chr 4:111,125,312...111,245,980

LUC7L

LUC7 like

acts_upstream_of_or_within

(MGI:3055693|PMID:15474286)

PMID:15474286

MGI:3055693

Ensembl chr16:177,857...217,519

SIRT2

sirtuin 2

involved_in

GO_REF:0000107

NCBI chr19:35,984,453...36,005,582
Ensembl chr19:44,533,965...44,554,799

SOX15

SRY-box transcription factor 15

acts_upstream_of_or_within
involved_in

(MGI:1858709|PMID:10821863)

PMID:10821863

GO_REF:0000107 MGI:1858709

NCBI chr17:7,619,804...7,621,791
Ensembl chr17:7,606,086...7,608,632

TWIST1

twist family bHLH transcription factor 1

involved_in

(MGI:1201268|PMID:9520323)

PMID:9520323

MGI:1201268

NCBI chr 7:19,761,041...19,765,665

negative regulation of ureter smooth muscle cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

sonic hedgehog signaling molecule

involved_in

GO_REF:0000107

NCBI chr 7:147,400,112...147,414,036
Ensembl chr 7:159,114,666...159,126,651

neuromuscular junction development, skeletal muscle fiber

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CNTNAP1

contactin associated protein 1

involved_in

GO_REF:0000107

NCBI chr17:14,618,294...14,635,193
Ensembl chr17:14,842,577...14,858,896

CNTNAP2

contactin associated protein 2

involved_in

(MGI:6269164|PMID:28370195)

PMID:28370195

MGI:6269164

NCBI chr 7:137,858,607...140,150,820
Ensembl chr 7:150,345,240...152,626,818

PMP22

peripheral myelin protein 22

acts_upstream_of_or_within

(MGI:5605930|PMID:25014022)

PMID:25014022

MGI:5605930

NCBI chr17:36,389,549...36,425,161
Ensembl chr17:41,038,302...41,073,872

planar cell polarity pathway involved in cardiac muscle tissue morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

LRP6

LDL receptor related protein 6

acts_upstream_of

(MGI:4830282|PMID:19056682)

PMID:19056682

MGI:4830282

NCBI chr12:12,121,411...12,288,590
Ensembl chr12:12,508,108...12,657,973

WNT5A

Wnt family member 5A

acts_upstream_of_or_within
involved_in

(MGI:4830282|PMID:19056682)

PMID:19056682

GO_REF:0000107 MGI:4830282

NCBI chr 3:55,396,279...55,418,579
Ensembl chr 3:56,621,380...56,638,051

positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

RBPJ

recombination signal binding protein for immunoglobulin kappa J region

acts_upstream_of_or_within

(MGI:5432296|PMID:22711842)

PMID:22711842

MGI:5432296

NCBI chr 4:20,719,548...20,835,439
Ensembl chr 4:25,995,263...26,107,683

positive regulation of cardiac muscle cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ARRB2

arrestin beta 2

involved_in

GO_REF:0000107

NCBI chr17:4,766,616...4,777,253
Ensembl chr17:4,757,048...4,767,517

EFNB2

ephrin B2

involved_in

(MGI:3701380|PMID:17336907)

NCBI chr13:87,629,831...87,675,652
Ensembl chr13:106,770,296...106,815,548

GSK3B

glycogen synthase kinase 3 beta

involved_in

(MGI:5784966|PMID:24974728)

PMID:24974728

MGI:5784966

NCBI chr 3:116,943,205...117,215,001
Ensembl chr 3:123,861,379...124,126,771

KAT2A

lysine acetyltransferase 2A

NCBI chr17:15,194,414...15,202,818
Ensembl chr17:15,416,075...15,424,197

myocyte enhancer factor 2C

involved_in

GO_REF:0000107

NCBI chr 5:26,480,489...26,650,813
Ensembl chr 5:26,681,700...26,786,426

MYOCD

myocardin

involved_in

InterPro
Ensembl

GO_REF:0000002 GO_REF:0000107

NCBI chr17:38,880,120...38,983,246
Ensembl chr17:43,584,259...43,681,659

neuregulin 1

involved_in

(MGI:3701380|PMID:17336907)

NCBI chr 8:30,954,852...32,084,411
Ensembl chr 8:29,050,222...29,263,977

TGFB1

transforming growth factor beta 1

involved_in

(PMID:25163461)

PMID:25163461

NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973

Wnt family member 3A

involved_in

GO_REF:0000107

NCBI chr 1:203,409,294...203,463,214
Ensembl chr 1:208,628,706...208,674,469

positive regulation of cardiac muscle cell proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BMP10

bone morphogenetic protein 10

involved_in

GO_REF:0000107

NCBI chr2A:68,901,944...68,912,559
Ensembl chr2A:70,023,655...70,034,420

bone morphogenetic protein receptor type 1A

involved_in

GO_REF:0000107

NCBI chr10:83,185,040...83,353,239
Ensembl chr10:86,837,469...86,912,912

cyclin B1

NCBI chr 5:44,826,103...44,836,832
Ensembl chr 5:46,394,362...46,405,332

cyclin D2

NCBI chr12:4,385,957...4,417,602
Ensembl chr12:4,309,272...4,335,551

CDK1

cyclin dependent kinase 1

NCBI chr10:57,314,692...57,331,261
Ensembl chr10:59,647,993...59,664,434

ERBB4

erb-b2 receptor tyrosine kinase 4

involved_in

GO_REF:0000107

NCBI chr2B:98,625,630...99,795,371
Ensembl chr2B:217,069,644...218,272,006

FGF2

fibroblast growth factor 2

involved_in

PMID:8603495 PMID:9553078

(PMID:9553078)

RGD
BHF-UCL

RGD:8655650

NCBI chr 4:115,005,136...115,076,369
Ensembl chr 4:126,149,813...126,214,942

FGF9

fibroblast growth factor 9

acts_upstream_of_or_within
involved_in

(MGI:3527351|PMID:15621532)
(MGI:3629544|PMID:16778080)

GO_REF:0000107 MGI:3527351 MGI:3629544

NCBI chr13:2,967,713...3,000,554
Ensembl chr13:21,273,333...21,307,198

FGFR1

fibroblast growth factor receptor 1

acts_upstream_of_or_within

PMID:15621532 PMID:16778080 PMID:18275970

(MGI:3629544|PMID:16778080)
(MGI:3527351|PMID:15621532)

RGD
MGI

MGI:3527351 MGI:3629544 RGD:10402047

NCBI chr 8:37,713,133...37,773,098
Ensembl chr 8:34,890,147...34,948,904

FGFR2

fibroblast growth factor receptor 2

acts_upstream_of_or_within

(MGI:3527351|PMID:15621532)
(MGI:3629544|PMID:16778080)

MGI:3527351 MGI:3629544

NCBI chr10:118,055,854...118,175,440
Ensembl chr10:121,469,735...121,588,815

GATA binding protein 4

acts_upstream_of_or_within

(MGI:3833786|PMID:19084512)

MGI:3833786

NCBI chr 8:7,442,921...7,526,731

GATA binding protein 6

acts_upstream_of_or_within
involved_in

(MGI:3833786|PMID:19084512)

GO_REF:0000107 MGI:3833786

NCBI chr18:15,411,764...15,444,402

GLI1

GLI family zinc finger 1

involved_in

GO_REF:0000107

NCBI chr12:31,453,759...31,466,194
Ensembl chr12:31,710,057...31,722,473

HEY2

hes related family bHLH transcription factor with YRPW motif 2

acts_upstream_of_or_within
involved_in

(MGI:3784153|PMID:17332425)

PMID:17332425

GO_REF:0000107 MGI:3784153

NCBI chr 6:123,527,180...123,538,794
Ensembl chr 6:127,647,547...127,659,056

MAPK1

mitogen-activated protein kinase 1

NCBI chr22:3,883,119...3,990,368
Ensembl chr22:20,365,487...20,450,335

MAPK14

mitogen-activated protein kinase 14

acts_upstream_of_or_within
involved_in

(MGI:5288131|PMID:21768366)

GO_REF:0000107 MGI:5288131

NCBI chr 6:35,586,847...35,683,041
Ensembl chr 6:36,788,233...36,871,114

myocyte enhancer factor 2C

involved_in

(MGI:3830899|PMID:16680724)

PMID:16680724

MGI:3830899

NCBI chr 5:26,480,489...26,650,813
Ensembl chr 5:26,681,700...26,786,426

NCAM1

neural cell adhesion molecule 1

NCBI chr11:107,845,507...108,160,441
Ensembl chr11:111,925,677...112,000,401

notch receptor 1

involved_in

GO_REF:0000107

NCBI chr 9:107,568,670...107,621,032
Ensembl chr 9:136,544,639...136,598,740

neuregulin 1

involved_in

(PMID:9553078)

PMID:9553078

NCBI chr 8:30,954,852...32,084,411
Ensembl chr 8:29,050,222...29,263,977

PIM1

Pim-1 proto-oncogene, serine/threonine kinase

involved_in

(PMID:21474815)

PMID:21474815

NCBI chr 6:36,730,669...36,735,954

RBPJ

recombination signal binding protein for immunoglobulin kappa J region

involved_in

(MGI:3701380|PMID:17336907)

NCBI chr 4:20,719,548...20,835,439
Ensembl chr 4:25,995,263...26,107,683

TBX2

T-box transcription factor 2

involved_in

GO_REF:0000107

NCBI chr17:55,501,932...55,511,537
Ensembl chr17:60,622,098...60,630,189

TBX20

T-box transcription factor 20

involved_in

(MGI:3579960|PMID:15901664)

PMID:15901664

MGI:3579960

NCBI chr 7:35,855,969...35,878,533

T-box transcription factor 5

involved_in
acts_upstream_of_or_within

(MGI:3833786|PMID:19084512)

GO_REF:0000107 MGI:3833786

NCBI chr12:111,954,222...112,009,261
Ensembl chr12:115,333,609...115,389,739

TGFBR3

transforming growth factor beta receptor 3

involved_in

(MGI:2663364|PMID:12773577)

PMID:12773577

MGI:2663364

NCBI chr 1:94,337,275...94,539,229
Ensembl chr 1:93,080,452...93,285,587

WNT2

Wnt family member 2

acts_upstream_of_or_within
involved_in

(MGI:4439199|PMID:20159597)

PMID:20159597

GO_REF:0000107 MGI:4439199

NCBI chr 7:109,244,772...109,291,472
Ensembl chr 7:121,936,031...121,985,862

YAP1

Yes1 associated transcriptional regulator

involved_in

GO_REF:0000107

NCBI chr11:97,061,367...97,186,961
Ensembl chr11:100,552,424...100,681,301

ZFPM2

zinc finger protein, FOG family member 2

involved_in

GO_REF:0000107

NCBI chr 8:101,872,850...102,430,622
Ensembl chr 8:104,023,062...104,576,688

positive regulation of cardiac muscle fiber development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BMP4

bone morphogenetic protein 4

involved_in

GO_REF:0000107

NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752

positive regulation of cardiac muscle tissue development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CREB1

cAMP responsive element binding protein 1

acts_upstream_of_or_within
involved_in

(MGI:5571433|PMID:24364879)

PMID:24364879

GO_REF:0000107 MGI:5571433

NCBI chr2B:94,762,796...94,836,304
Ensembl chr2B:212,891,261...212,958,130

ERBB3

erb-b2 receptor tyrosine kinase 3

acts_upstream_of_or_within
involved_in

(MGI:5571433|PMID:24364879)

PMID:24364879

GO_REF:0000107 MGI:5571433

NCBI chr12:32,811,533...32,834,958
Ensembl chr12:33,063,434...33,084,994

positive regulation of cell growth involved in cardiac muscle cell development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adrenoceptor beta 1

NCBI chr10:110,642,491...110,646,595

AKAP6

A-kinase anchoring protein 6

PMID:16306226 PMID:21550986

RGD

RGD:2312613 RGD:6902940

NCBI chr14:12,978,221...13,602,732
Ensembl chr14:31,395,026...31,792,166

CCN4

cellular communication network factor 4

NCBI chr 8:129,842,580...129,884,528
Ensembl chr 8:132,818,397...132,858,861

DDX39B

DExD-box helicase 39B

NCBI chr 6:31,191,333...31,203,246
Ensembl chr 6:32,081,210...32,092,569

EDN1

endothelin 1

involved_in

GO_REF:0000107

NCBI chr 6:12,076,312...12,142,861
Ensembl chr 6:12,462,718...12,503,545

EP300

E1A binding protein p300

NCBI chr22:21,986,467...22,076,921
Ensembl chr22:40,079,503...40,168,604

FDPS

farnesyl diphosphate synthase

NCBI chr 1:130,653,316...130,665,196
Ensembl chr 1:134,258,968...134,270,237

HAMP

hepcidin antimicrobial peptide

NCBI chr19:32,228,701...32,231,494
Ensembl chr19:40,964,445...40,968,861

IGF1

insulin like growth factor 1

involved_in

(PMID:24117217)

PMID:24117217

NCBI chr12:99,986,887...100,066,773
Ensembl chr12:103,385,911...103,462,177

MTOR

mechanistic target of rapamycin kinase

PMID:21318349 PMID:21933187

RGD

RGD:10040977 RGD:10040978

NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841

NR3C1

nuclear receptor subfamily 3 group C member 1

NCBI chr 5:138,634,278...139,089,171
Ensembl chr 5:144,741,452...144,865,269

PARP2

poly(ADP-ribose) polymerase 2

NCBI chr14:1,215,727...1,230,006
Ensembl chr14:19,269,046...19,282,853

PIN1

peptidylprolyl cis/trans isomerase, NIMA-interacting 1

NCBI chr19:9,389,829...9,404,099
Ensembl chr19:10,053,254...10,066,853

sirtuin 1

NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069

SLC25A4

solute carrier family 25 member 4

NCBI chr 4:177,310,982...177,315,016
Ensembl chr 4:189,531,914...189,534,549

TRIP10

thyroid hormone receptor interactor 10

NCBI chr19:5,772,225...5,784,078
Ensembl chr19:6,693,646...6,705,399

positive regulation of kidney smooth muscle cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

sonic hedgehog signaling molecule

involved_in

GO_REF:0000107

NCBI chr 7:147,400,112...147,414,036
Ensembl chr 7:159,114,666...159,126,651

positive regulation of muscle tissue development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

PPARGC1A

PPARG coactivator 1 alpha

involved_in

GO_REF:0000107

NCBI chr 4:18,196,431...18,876,889
Ensembl chr 4:23,483,377...23,581,212

positive regulation of skeletal muscle cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ARNTL

aryl hydrocarbon receptor nuclear translocator like

involved_in

(MGI:5553223|PMID:23525013)

PMID:23525013

MGI:5553223

NCBI chr11:13,436,580...13,547,135
Ensembl chr11:13,163,028...13,240,376

GPC1

glypican 1

acts_upstream_of_or_within
involved_in

(PMID:20100867)

UniProt
Ensembl

PMID:20100867

GO_REF:0000107

NCBI chr2B:127,684,839...127,717,294
Ensembl chr2B:246,511,082...246,523,569

myocyte enhancer factor 2C

involved_in

GO_REF:0000107

NCBI chr 5:26,480,489...26,650,813
Ensembl chr 5:26,681,700...26,786,426

positive regulation of skeletal muscle fiber development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACTN3

actinin alpha 3

involved_in

GO_REF:0000107

NCBI chr11:61,905,722...61,922,227
Ensembl chr11:65,228,713...65,245,429

BCL2

BCL2 apoptosis regulator

acts_upstream_of_or_within
involved_in

(MGI:1928555|PMID:11146504)

PMID:11146504

GO_REF:0000107 MGI:1928555

NCBI chr18:56,481,212...56,679,012
Ensembl chr18:59,802,443...59,992,100

LMOD3

leiomodin 3

involved_in

GO_REF:0000107

NCBI chr 3:69,042,870...69,058,704
Ensembl chr 3:70,410,288...70,424,702

MYOG

myogenin

involved_in

GO_REF:0000107

NCBI chr 1:178,684,933...178,687,971
Ensembl chr 1:182,979,700...182,982,611

short stature homeobox 2

involved_in

GO_REF:0000107

NCBI chr 3:155,138,969...155,149,619
Ensembl chr 3:163,190,284...163,199,239

positive regulation of skeletal muscle fiber differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

RBM24

RNA binding motif protein 24

involved_in

(MGI:6148527|PMID:25313962)

PMID:25313962

MGI:6148527

NCBI chr 6:17,140,450...17,153,035

positive regulation of skeletal muscle tissue development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CDON

cell adhesion associated, oncogene regulated

acts_upstream_of_or_within
involved_in

(MGI:3522534|PMID:15572127)

PMID:15572127

GO_REF:0000107 MGI:3522534

NCBI chr11:120,772,160...120,877,529
Ensembl chr11:124,685,084...124,786,091

CTNNB1

catenin beta 1

involved_in

GO_REF:0000107

NCBI chr 3:41,104,940...41,145,934
Ensembl chr 3:41,373,726...41,414,030

FLOT1

flotillin 1

involved_in

GO_REF:0000107

NCBI chr 6:30,472,839...30,487,809
Ensembl chr 6:31,342,033...31,357,559

HMGCR

3-hydroxy-3-methylglutaryl-CoA reductase

NCBI chr 5:39,936,630...39,961,519
Ensembl chr 5:40,548,919...40,573,785

myocyte enhancer factor 2C

involved_in

GO_REF:0000107

NCBI chr 5:26,480,489...26,650,813
Ensembl chr 5:26,681,700...26,786,426

PRKAA1

protein kinase AMP-activated catalytic subunit alpha 1

acts_upstream_of_or_within
involved_in

(MGI:5569711|PMID:23926128)

PMID:23926128

GO_REF:0000107 MGI:5569711

NCBI chr 5:69,581,748...69,620,721
Ensembl chr 5:74,627,830...74,666,505

sonic hedgehog signaling molecule

involved_in
acts_upstream_of_or_within

(MGI:1929969|PMID:11171399)

PMID:11171399

GO_REF:0000107 MGI:1929969

NCBI chr 7:147,400,112...147,414,036
Ensembl chr 7:159,114,666...159,126,651

USP2

ubiquitin specific peptidase 2

involved_in

PMID:10938131

NCBI chr11:114,196,725...114,223,411
Ensembl chr11:118,124,350...118,150,868

Wnt family member 3A

involved_in

GO_REF:0000107

NCBI chr 1:203,409,294...203,463,214
Ensembl chr 1:208,628,706...208,674,469

positive regulation of skeletal muscle tissue growth

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACTN3

actinin alpha 3

involved_in

GO_REF:0000107

NCBI chr11:61,905,722...61,922,227
Ensembl chr11:65,228,713...65,245,429

adrenoceptor beta 2

NCBI chr 5:144,259,756...144,398,421
Ensembl chr 5:150,267,554...150,315,892

DLL1

delta like canonical Notch ligand 1

involved_in

GO_REF:0000107

NCBI chr 6:168,440,192...168,449,071
Ensembl chr 6:173,534,292...173,544,759

IGF2

insulin like growth factor 2

involved_in

GO_REF:0000107

NCBI chr11:2,170,190...2,199,442
Ensembl chr11:2,202,743...2,228,890

MTM1

myotubularin 1

acts_upstream_of_or_within

(MGI:5510937|PMID:23695157)

PMID:23695157

MGI:5510937

NCBI chr X:140,218,742...140,323,495
Ensembl chr X:150,174,758...150,255,381

NACA

nascent polypeptide associated complex subunit alpha

involved_in

(MGI:4867362|PMID:21071677)

PMID:21071677

MGI:4867362

NCBI chr12:32,180,823...32,195,645
Ensembl chr12:32,434,366...32,447,510

RPS6KB1

ribosomal protein S6 kinase B1

NCBI chr17:53,958,807...54,014,752
Ensembl chr17:58,799,069...58,853,653

positive regulation of striated muscle tissue development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

GJA1

gap junction protein alpha 1

acts_upstream_of_or_within

(MGI:3513707|PMID:15601660)

PMID:15601660

MGI:3513707

NCBI chr 6:119,213,513...119,227,617

MRTFB

myocardin related transcription factor B

involved_in

GO_REF:0000107

NCBI chr16:12,999,165...13,195,012
Ensembl chr16:14,493,351...14,613,860

positive regulation of tongue muscle cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CYP26B1

cytochrome P450 family 26 subfamily B member 1

involved_in

GO_REF:0000107

NCBI chr2A:72,172,658...72,191,410
Ensembl chr2A:73,670,830...73,686,433

TBX1

T-box transcription factor 1

involved_in

(MGI:3809313|PMID:18816858)

PMID:18816858

MGI:3809313

NCBI chr22:2,521,080...2,541,267

positive regulation of ureter smooth muscle cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

sonic hedgehog signaling molecule

involved_in

GO_REF:0000107

NCBI chr 7:147,400,112...147,414,036
Ensembl chr 7:159,114,666...159,126,651

post-embryonic cardiac muscle cell growth involved in heart morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

sirtuin 6

NCBI chr19:3,196,092...3,204,602
Ensembl chr19:4,146,057...4,154,126

pulmonary myocardium development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

NK2 homeobox 5

acts_upstream_of_or_within
involved_in

(MGI:3818134|PMID:17823370)

PMID:17823370

GO_REF:0000107 MGI:3818134

NCBI chr 5:168,584,197...168,589,406
Ensembl chr 5:175,492,288...175,495,514

paired like homeodomain 2

acts_upstream_of_or_within

(MGI:3818134|PMID:17823370)

PMID:17823370

MGI:3818134

NCBI chr 4:103,112,624...103,137,356

SEMA3C

semaphorin 3C

acts_upstream_of_or_within
involved_in

(PMID:19666519)

PMID:19666519

GO_REF:0000107

NCBI chr 7:72,706,615...72,884,163
Ensembl chr 7:86,368,753...86,545,580

Purkinje myocyte development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

DSG2

desmoglein 2

involved_in

GO_REF:0000107

NCBI chr18:24,716,181...24,766,837
Ensembl chr18:28,313,223...28,363,786

IRX3

iroquois homeobox 3

involved_in

GO_REF:0000107

NCBI chr16:34,514,107...34,517,576
Ensembl chr16:53,622,409...53,624,653

Purkinje myocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

NK2 homeobox 5

acts_upstream_of_or_within
involved_in

(MGI:3785685|PMID:17250822)

PMID:17250822

GO_REF:0000107 MGI:3785685

NCBI chr 5:168,584,197...168,589,406
Ensembl chr 5:175,492,288...175,495,514

regulation of cardiac muscle cell proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

bone morphogenetic protein receptor type 1A

involved_in

GO_REF:0000107

NCBI chr10:83,185,040...83,353,239
Ensembl chr10:86,837,469...86,912,912

FGF20

fibroblast growth factor 20

acts_upstream_of_or_within
involved_in

(MGI:4829405|PMID:20713518)

PMID:20713518

GO_REF:0000107 MGI:4829405

NCBI chr 8:16,205,791...16,216,257
Ensembl chr 8:13,151,867...13,161,216

FOXP1

forkhead box P1

acts_upstream_of_or_within

(MGI:4829405|PMID:20713518)

PMID:20713518

MGI:4829405

NCBI chr 3:70,893,933...71,523,892
Ensembl chr 3:72,258,456...72,498,173

GATA binding protein 4

acts_upstream_of_or_within

(MGI:3581473|PMID:15902305)

PMID:15902305

MGI:3581473

NCBI chr 8:7,442,921...7,526,731

MAPK11

mitogen-activated protein kinase 11

acts_upstream_of_or_within
involved_in

(MGI:5288131|PMID:21768366)

GO_REF:0000107 MGI:5288131

NCBI chr22:30,492,664...30,499,456
Ensembl chr22:49,492,693...49,495,732

NK2 homeobox 5

acts_upstream_of_or_within
involved_in

(MGI:4829405|PMID:20713518)

PMID:20713518

GO_REF:0000107 MGI:4829405

NCBI chr 5:168,584,197...168,589,406
Ensembl chr 5:175,492,288...175,495,514

TGFBR1

transforming growth factor beta receptor 1

involved_in

GO_REF:0000107

NCBI chr 9:70,195,007...70,243,514
Ensembl chr 9:98,332,739...98,362,748

regulation of cardiac muscle tissue development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

JPH2

junctophilin 2

involved_in

(MGI:1861885|PMID:10949023)

PMID:10949023

MGI:1861885

NCBI chr20:40,439,975...40,517,438

regulation of cell growth involved in cardiac muscle cell development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

COL14A1

collagen type XIV alpha 1 chain

acts_upstream_of_or_within

(MGI:5444801|PMID:22906538)

PMID:22906538

MGI:5444801

NCBI chr 8:116,818,467...117,065,385
Ensembl chr 8:119,610,929...119,831,880

regulation of skeletal muscle cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

DDX17

DEAD-box helicase 17

involved_in

GO_REF:0000107

NCBI chr22:19,398,801...19,421,587
Ensembl chr22:37,218,884...37,241,425

DDX5

DEAD-box helicase 5

involved_in

(MGI:5315343|PMID:17011493)

PMID:17011493

MGI:5315343

NCBI chr17:58,594,956...58,603,570
Ensembl chr17:63,689,082...63,696,142

KLHL41

kelch like family member 41

acts_upstream_of_or_within
involved_in

(MGI:5424274|PMID:22562206)

PMID:22562206

GO_REF:0000107 MGI:5424274

NCBI chr2B:56,778,475...56,798,317
Ensembl chr2B:174,248,884...174,265,508

LOC100982351

ubiquinol-cytochrome-c reductase complex assembly factor 2

involved_in

GO_REF:0000107

NCBI chr 6:33,270,785...33,284,931
Ensembl chr 6:34,379,212...34,393,373

NR1D2

nuclear receptor subfamily 1 group D member 2

involved_in

GO_REF:0000107

NCBI chr 3:23,857,317...23,892,533
Ensembl chr 3:24,185,798...24,215,831

RBFOX1

RNA binding fox-1 homolog 1

acts_upstream_of_or_within
involved_in

(MGI:5485311|PMID:23349951)

PMID:23349951

GO_REF:0000107 MGI:5485311

NCBI chr16:4,162,659...6,640,962
Ensembl chr16:5,418,607...7,889,215

SIX1

SIX homeobox 1

involved_in

GO_REF:0000107

NCBI chr14:41,250,512...41,256,567
Ensembl chr14:59,515,324...59,527,494

regulation of skeletal muscle fiber development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

FBXO22

F-box protein 22

acts_upstream_of_or_within

(MGI:3840749|PMID:19319192)

PMID:19319192

MGI:3840749

NCBI chr15:54,817,076...54,849,271
Ensembl chr15:74,410,213...74,441,609

HDAC4

histone deacetylase 4

involved_in
acts_upstream_of_or_within

(MGI:3763703|PMID:17786239)

GO_REF:0000107 MGI:3763703

NCBI chr2B:126,287,745...126,649,815
Ensembl chr2B:245,123,061...245,427,054

HDAC5

histone deacetylase 5

acts_upstream_of_or_within

(MGI:3763703|PMID:17786239)

NCBI chr17:13,273,052...13,319,695
Ensembl chr17:13,446,836...13,479,140

HDAC9

histone deacetylase 9

acts_upstream_of_or_within

(MGI:3763703|PMID:17786239)

NCBI chr 7:18,740,580...19,653,615
Ensembl chr 7:18,138,761...18,970,717

NACA

nascent polypeptide associated complex subunit alpha

involved_in

(MGI:4867362|PMID:21071677)

PMID:21071677

MGI:4867362

NCBI chr12:32,180,823...32,195,645
Ensembl chr12:32,434,366...32,447,510

regulation of skeletal muscle fiber differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

HDAC4

histone deacetylase 4

acts_upstream_of_or_within
involved_in

(MGI:3763703|PMID:17786239)

GO_REF:0000107 MGI:3763703

NCBI chr2B:126,287,745...126,649,815
Ensembl chr2B:245,123,061...245,427,054

HDAC5

histone deacetylase 5

acts_upstream_of_or_within

(MGI:3763703|PMID:17786239)

NCBI chr17:13,273,052...13,319,695
Ensembl chr17:13,446,836...13,479,140

HDAC9

histone deacetylase 9

acts_upstream_of_or_within

(MGI:3763703|PMID:17786239)

NCBI chr 7:18,740,580...19,653,615
Ensembl chr 7:18,138,761...18,970,717

NLN

neurolysin

acts_upstream_of_or_within
involved_in

(MGI:5588076|PMID:24719333)

PMID:24719333

GO_REF:0000107 MGI:5588076

NCBI chr 5:48,180,768...48,283,281
Ensembl chr 5:49,840,482...49,938,192

regulation of skeletal muscle tissue development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACVR1

activin A receptor type 1

involved_in

PMID:12968668

NCBI chr2B:44,994,175...45,133,490
Ensembl chr2B:162,234,823...162,297,805

MEGF10

multiple EGF like domains 10

involved_in

GO_REF:0000107

NCBI chr 5:122,639,155...122,877,324
Ensembl chr 5:128,466,095...128,641,043

TCF7L2

transcription factor 7 like 2

acts_upstream_of_or_within

(MGI:4879035|PMID:21177349)

PMID:21177349

MGI:4879035

NCBI chr10:109,541,524...109,759,499
Ensembl chr10:112,978,167...113,192,281

WNT10B

Wnt family member 10B

acts_upstream_of_or_within
involved_in

(MGI:3581945|PMID:15673614)

PMID:15673614

GO_REF:0000107 MGI:3581945

NCBI chr12:39,771,163...39,785,411
Ensembl chr12:40,659,106...40,665,734

regulation of skeletal muscle tissue growth

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

DLL1

delta like canonical Notch ligand 1

involved_in

GO_REF:0000107

NCBI chr 6:168,440,192...168,449,071
Ensembl chr 6:173,534,292...173,544,759

regulation of smooth muscle tissue development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

TNN

tenascin N

involved_in

GO_REF:0000107

NCBI chr 1:150,580,248...150,661,687
Ensembl chr 1:154,278,714...154,357,823

regulation of striated muscle tissue development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CENPF

centromere protein F

acts_upstream_of_or_within
involved_in

(MGI:1339480|PMID:10373470)

PMID:10373470

GO_REF:0000107 MGI:1339480

NCBI chr 1:190,170,414...190,231,478
Ensembl chr 1:195,024,877...195,086,518

LOX

lysyl oxidase

acts_upstream_of_or_within
involved_in

(MGI:5634219|PMID:25715398)

PMID:25715398

GO_REF:0000107 MGI:5634219

NCBI chr 5:117,450,833...117,464,957
Ensembl chr 5:123,234,662...123,248,717

SMAD3

SMAD family member 3

acts_upstream_of_or_within
involved_in

(MGI:2153314|PMID:11711431)

PMID:11711431

GO_REF:0000107 MGI:2153314

NCBI chr15:46,013,764...46,143,126
Ensembl chr15:64,284,949...64,414,185

TGFB1

transforming growth factor beta 1

acts_upstream_of_or_within
involved_in

(MGI:2153314|PMID:11711431)

PMID:11711431

GO_REF:0000107 MGI:2153314

NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973

right ventricular cardiac muscle tissue morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

NK2 homeobox 5

involved_in

GO_REF:0000107

NCBI chr 5:168,584,197...168,589,406
Ensembl chr 5:175,492,288...175,495,514

ZFPM2

zinc finger protein, FOG family member 2

involved_in

GO_REF:0000107

NCBI chr 8:101,872,850...102,430,622
Ensembl chr 8:104,023,062...104,576,688

right ventricular compact myocardium morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CHD7

chromodomain helicase DNA binding protein 7

involved_in
acts_upstream_of_or_within

(MGI:5694290|PMID:26102480)

PMID:26102480

GO_REF:0000107 MGI:5694290

NCBI chr 8:57,091,002...57,282,471
Ensembl chr 8:58,816,840...58,945,186

sinoatrial node cell development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BVES

blood vessel epicardial substance

acts_upstream_of_or_within
involved_in

(MGI:5424322|PMID:22354168)

PMID:22354168

GO_REF:0000107 MGI:5424322

NCBI chr 6:102,915,148...102,951,141
Ensembl chr 6:106,787,615...106,822,050

ISL1

ISL LIM homeobox 1

involved_in

GO_REF:0000107

NCBI chr 5:62,635,095...62,650,141
Ensembl chr 5:64,252,715...64,264,674

POPDC2

popeye domain containing 2

acts_upstream_of_or_within

(MGI:5424322|PMID:22354168)

PMID:22354168

MGI:5424322

NCBI chr 3:116,761,474...116,780,369
Ensembl chr 3:123,673,815...123,692,684

short stature homeobox 2

involved_in

GO_REF:0000107

NCBI chr 3:155,138,969...155,149,619
Ensembl chr 3:163,190,284...163,199,239

TBX18

T-box transcription factor 18

involved_in

GO_REF:0000107

NCBI chr 6:82,621,987...82,654,137
Ensembl chr 6:85,862,810...85,938,799

T-box transcription factor 3

acts_upstream_of_or_within
involved_in

(MGI:4366226|PMID:19096026)

PMID:19096026

GO_REF:0000107 MGI:4366226

NCBI chr12:112,240,050...112,254,299
Ensembl chr12:115,620,002...115,631,316

sinoatrial node cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

MESP1

mesoderm posterior bHLH transcription factor 1

involved_in

GO_REF:0000107

NCBI chr15:68,440,626...68,441,935
Ensembl chr15:87,645,768...87,647,210

sinoatrial node cell fate commitment

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

TBX18

T-box transcription factor 18

involved_in

GO_REF:0000107

NCBI chr 6:82,621,987...82,654,137
Ensembl chr 6:85,862,810...85,938,799

sinoatrial node development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

GATA binding protein 6

involved_in

GO_REF:0000107

NCBI chr18:15,411,764...15,444,402

short stature homeobox 2

involved_in

GO_REF:0000107

NCBI chr 3:155,138,969...155,149,619
Ensembl chr 3:163,190,284...163,199,239

TBX18

T-box transcription factor 18

acts_upstream_of_or_within

(MGI:4366226|PMID:19096026)

PMID:19096026

MGI:4366226

NCBI chr 6:82,621,987...82,654,137
Ensembl chr 6:85,862,810...85,938,799

T-box transcription factor 5

involved_in

GO_REF:0000107

NCBI chr12:111,954,222...112,009,261
Ensembl chr12:115,333,609...115,389,739

skeletal muscle cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ANKRD1

ankyrin repeat domain 1

acts_upstream_of_or_within
involved_in

(MGI:5300631|PMID:22147266)

GO_REF:0000107 MGI:5300631

NCBI chr10:87,652,254...87,661,173
Ensembl chr10:91,180,034...91,188,165

ANKRD2

ankyrin repeat domain 2

acts_upstream_of_or_within

(MGI:5300631|PMID:22147266)

NCBI chr10:94,192,920...94,204,400
Ensembl chr10:97,686,121...97,697,238

ANKRD33

ankyrin repeat domain 33

acts_upstream_of_or_within

(MGI:5300631|PMID:22147266)

NCBI chr12:36,870,696...36,875,247

ASB2

ankyrin repeat and SOCS box containing 2

acts_upstream_of_or_within
involved_in

(MGI:5300631|PMID:22147266)

GO_REF:0000107 MGI:5300631

NCBI chr14:74,566,607...74,608,905
Ensembl chr14:93,900,914...93,930,527

ATF3

activating transcription factor 3

acts_upstream_of_or_within
involved_in

(MGI:5300631|PMID:22147266)

GO_REF:0000107 MGI:5300631

NCBI chr 1:188,176,728...188,188,842
Ensembl chr 1:193,036,793...193,049,150

BARX2

BARX homeobox 2

acts_upstream_of_or_within
involved_in

(MGI:2651740|PMID:12486129)

PMID:12486129

GO_REF:0000107 MGI:2651740

NCBI chr11:124,187,026...124,264,154
Ensembl chr11:128,086,409...128,162,833

BCL9

BCL9 transcription coactivator

involved_in
acts_upstream_of_or_within

(MGI:4368064|PMID:19699733)

PMID:19699733

GO_REF:0000107 MGI:4368064

NCBI chr 1:122,982,604...123,067,299
Ensembl chr 1:112,463,904...112,478,264

BCL9L

BCL9 like

acts_upstream_of_or_within
involved_in

(MGI:4368064|PMID:19699733)

PMID:19699733

GO_REF:0000107 MGI:4368064

NCBI chr11:113,735,852...113,765,811
Ensembl chr11:117,666,995...117,678,598

BTG2

BTG anti-proliferation factor 2

acts_upstream_of_or_within
involved_in

(MGI:5300631|PMID:22147266)

GO_REF:0000107 MGI:5300631

NCBI chr 1:178,907,317...178,911,410
Ensembl chr 1:183,201,297...183,205,404

CITED2

Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2

acts_upstream_of_or_within

(MGI:5300631|PMID:22147266)

NCBI chr 6:137,134,142...137,136,550

COPS2

COP9 signalosome subunit 2

acts_upstream_of_or_within
involved_in

(MGI:5300631|PMID:22147266)

GO_REF:0000107 MGI:5300631

NCBI chr15:28,073,237...28,103,615
Ensembl chr15:46,396,077...46,426,396

DMRTA2

DMRT like family A2

acts_upstream_of_or_within

(MGI:5300631|PMID:22147266)

NCBI chr 1:49,659,379...49,665,262

EEF2

eukaryotic translation elongation factor 2

NCBI chr19:3,000,608...3,009,918
Ensembl chr19:3,950,772...3,960,172

EGR1

early growth response 1

acts_upstream_of_or_within
involved_in

(MGI:5300631|PMID:22147266)

GO_REF:0000107 MGI:5300631

NCBI chr 5:133,845,305...133,849,291
Ensembl chr 5:139,975,635...139,979,260

EGR2

early growth response 2

acts_upstream_of_or_within
involved_in

(MGI:5300631|PMID:22147266)

GO_REF:0000107 MGI:5300631

NCBI chr10:59,320,073...59,326,869
Ensembl chr10:61,648,364...61,652,846

EMD

emerin

acts_upstream_of_or_within

(MGI:4366679|PMID:19720741)

PMID:19720741

MGI:4366679

NCBI chr X:143,792,178...143,794,530

EOMES

eomesodermin

acts_upstream_of_or_within

(MGI:5300631|PMID:22147266)

NCBI chr 3:27,601,829...27,608,701
Ensembl chr 3:27,925,086...27,930,274

FOS

Fos proto-oncogene, AP-1 transcription factor subunit

acts_upstream_of_or_within
involved_in

(MGI:5300631|PMID:22147266)

GO_REF:0000107 MGI:5300631

NCBI chr14:55,832,570...55,835,984
Ensembl chr14:74,676,316...74,679,766

FOXN2

forkhead box N2

acts_upstream_of_or_within
involved_in

(MGI:5300631|PMID:22147266)

GO_REF:0000107 MGI:5300631

NCBI chr2A:48,441,683...48,506,631
Ensembl chr2A:49,364,147...49,428,502

GTF3C5

general transcription factor IIIC subunit 5

acts_upstream_of_or_within
involved_in

(MGI:5300631|PMID:22147266)

GO_REF:0000107 MGI:5300631

NCBI chr 9:104,150,392...104,178,242
Ensembl chr 9:132,779,664...132,807,518

HEYL

hes related family bHLH transcription factor with YRPW motif like

acts_upstream_of_or_within
involved_in

(MGI:5300631|PMID:22147266)

GO_REF:0000107 MGI:5300631

NCBI chr 1:38,913,549...38,929,798
Ensembl chr 1:40,240,118...40,256,933

HIVEP3

HIVEP zinc finger 3

acts_upstream_of_or_within
involved_in

(MGI:5300631|PMID:22147266)

GO_REF:0000107 MGI:5300631

NCBI chr 1:40,805,355...41,335,290
Ensembl chr 1:42,120,741...42,203,313

HLF

HLF transcription factor, PAR bZIP family member

acts_upstream_of_or_within
involved_in

(MGI:5300631|PMID:22147266)

GO_REF:0000107 MGI:5300631

NCBI chr17:49,353,790...49,413,676
Ensembl chr17:54,218,399...54,278,044

HMG20B

high mobility group 20B

acts_upstream_of_or_within
involved_in

(MGI:5300631|PMID:22147266)

GO_REF:0000107 MGI:5300631

NCBI chr19:2,598,588...2,604,799
Ensembl chr19:3,548,451...3,554,725

KLF5

Kruppel like factor 5

acts_upstream_of_or_within
involved_in

(MGI:5300631|PMID:22147266)

GO_REF:0000107 MGI:5300631

NCBI chr13:54,287,578...54,310,216

KLHL41

kelch like family member 41

involved_in

Ensembl
InterPro

GO_REF:0000002 GO_REF:0000107

NCBI chr2B:56,778,475...56,798,317
Ensembl chr2B:174,248,884...174,265,508

KRAS

KRAS proto-oncogene, GTPase

acts_upstream_of_or_within
involved_in

(MGI:3511080|PMID:15542848)

PMID:15542848

GO_REF:0000107 MGI:3511080

NCBI chr12:61,062,689...61,108,524
Ensembl chr12:63,679,293...63,724,335

LEMD2

LEM domain nuclear envelope protein 2

acts_upstream_of_or_within

(MGI:4366679|PMID:19720741)
(PMID:19720741)

PMID:19720741

MGI:4366679

NCBI chr 6:33,344,372...33,363,143

LEMD3

LEM domain containing 3

acts_upstream_of_or_within

(MGI:4366679|PMID:19720741)

PMID:19720741

MGI:4366679

NCBI chr12:23,668,368...23,747,369
Ensembl chr12:24,172,749...24,252,314

MAFF

MAF bZIP transcription factor F

acts_upstream_of_or_within

(MGI:5300631|PMID:22147266)

NCBI chr22:19,114,929...19,129,901

MED20

mediator complex subunit 20

acts_upstream_of_or_within
involved_in

(MGI:5300631|PMID:22147266)

GO_REF:0000107 MGI:5300631

NCBI chr 6:41,489,079...41,504,572
Ensembl chr 6:42,790,975...42,806,538

myocyte enhancer factor 2C

acts_upstream_of_or_within

(MGI:5300631|PMID:22147266)

NCBI chr 5:26,480,489...26,650,813
Ensembl chr 5:26,681,700...26,786,426

MEF2D

myocyte enhancer factor 2D

acts_upstream_of_or_within
involved_in

(MGI:5300631|PMID:22147266)

GO_REF:0000107 MGI:5300631

NCBI chr 1:131,806,705...131,844,420
Ensembl chr 1:135,637,801...135,653,866

MYC

MYC proto-oncogene, bHLH transcription factor

acts_upstream_of_or_within

(MGI:5300631|PMID:22147266)

NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863

MYF5

myogenic factor 5

acts_upstream_of_or_within
involved_in

(MGI:5300631|PMID:22147266)

GO_REF:0000107 MGI:5300631

NCBI chr12:78,236,945...78,239,701
Ensembl chr12:81,347,324...81,350,389

MYF6

myogenic factor 6

acts_upstream_of_or_within
involved_in

(MGI:5300631|PMID:22147266)

GO_REF:0000107 MGI:5300631

NCBI chr12:78,226,562...78,229,470
Ensembl chr12:81,338,339...81,340,176

MYLK2

myosin light chain kinase 2

involved_in

GO_REF:0000107

NCBI chr20:28,113,024...28,128,142
Ensembl chr20:29,243,391...29,258,508

MYOD1

myogenic differentiation 1

acts_upstream_of_or_within
involved_in

(MGI:5300631|PMID:22147266)

GO_REF:0000107 MGI:5300631

NCBI chr11:17,772,317...17,774,884
Ensembl chr11:17,456,124...17,458,690

NGFR

nerve growth factor receptor

NCBI chr17:8,089,600...8,109,361
Ensembl chr17:8,075,316...8,094,966

notch receptor 1

acts_upstream_of_or_within
involved_in

(MGI:5300631|PMID:22147266)

GO_REF:0000107 MGI:5300631

NCBI chr 9:107,568,670...107,621,032
Ensembl chr 9:136,544,639...136,598,740

NR4A1

nuclear receptor subfamily 4 group A member 1

acts_upstream_of_or_within
involved_in

(MGI:5300631|PMID:22147266)

GO_REF:0000107 MGI:5300631

NCBI chr12:36,703,903...36,740,211
Ensembl chr12:37,480,300...37,501,188

NUPR1

nuclear protein 1, transcriptional regulator

acts_upstream_of_or_within

(MGI:4360820|PMID:19723804)

PMID:19723804

MGI:4360820

Ensembl chr16:29,015,155...29,016,987

PAX5

paired box 5

acts_upstream_of_or_within
involved_in

(MGI:5300631|PMID:22147266)

GO_REF:0000107 MGI:5300631

NCBI chr 9:36,677,369...36,876,678
Ensembl chr 9:37,474,267...37,673,684

PHOX2B

paired like homeobox 2B

acts_upstream_of_or_within
involved_in

(MGI:5300631|PMID:22147266)

GO_REF:0000107 MGI:5300631

NCBI chr 4:36,070,924...36,074,532
Ensembl chr 4:41,919,742...41,922,449

PLAGL1

PLAG1 like zinc finger 1

acts_upstream_of_or_within

(MGI:5300631|PMID:22147266)

NCBI chr 6:141,715,599...141,841,862
Ensembl chr 6:146,435,622...146,480,224

RB1

RB transcriptional corepressor 1

acts_upstream_of_or_within
involved_in

(MGI:5300631|PMID:22147266)
(MGI:3511080|PMID:15542848)

PMID:15542848 PMID:22147266

GO_REF:0000107 MGI:3511080 MGI:5300631

NCBI chr13:29,453,872...29,624,665
Ensembl chr13:48,155,795...48,324,575

SAP30

Sin3A associated protein 30

acts_upstream_of_or_within

(MGI:5300631|PMID:22147266)

NCBI chr 4:165,598,765...165,605,737

SCX

scleraxis bHLH transcription factor

acts_upstream_of_or_within

(MGI:5300631|PMID:22147266)

NCBI chr 8:141,027,765...141,031,194

SMYD1

SET and MYND domain containing 1

acts_upstream_of_or_within
involved_in

(MGI:5300631|PMID:22147266)

GO_REF:0000107 MGI:5300631

NCBI chr2A:87,201,207...87,246,416
Ensembl chr2A:89,108,642...89,155,797

SNW1

SNW domain containing 1

acts_upstream_of_or_within

(MGI:5300631|PMID:22147266)

NCBI chr14:58,271,830...58,315,773
Ensembl chr14:77,472,387...77,517,315

SOX11

SRY-box transcription factor 11

acts_upstream_of_or_within

(MGI:5297659|PMID:20847309)

PMID:20847309

MGI:5297659

NCBI chr2A:5,699,738...5,711,210

SOX8

SRY-box transcription factor 8

acts_upstream_of_or_within

(MGI:5300631|PMID:22147266)

ventral anterior homeobox 1

acts_upstream_of_or_within

(MGI:5300631|PMID:22147266)

NCBI chr10:113,710,934...113,720,671

Wnt family member 3A

acts_upstream_of_or_within
involved_in

(MGI:4368064|PMID:19699733)

PMID:19699733

GO_REF:0000107 MGI:4368064

NCBI chr 1:203,409,294...203,463,214
Ensembl chr 1:208,628,706...208,674,469

ZNF689

zinc finger protein 689

acts_upstream_of_or_within
involved_in

(MGI:5300631|PMID:22147266)

GO_REF:0000107 MGI:5300631

NCBI chr16:24,356,711...24,365,116
Ensembl chr16:30,973,859...30,981,882

skeletal muscle fiber development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACTA1

actin alpha 1, skeletal muscle

involved_in

GO_REF:0000107

NCBI chr 1:204,975,646...204,978,523
Ensembl chr 1:210,007,622...210,010,469

BCL2

BCL2 apoptosis regulator

acts_upstream_of
involved_in

(MGI:1928555|PMID:11146504)

PMID:11146504

GO_REF:0000107 MGI:1928555

NCBI chr18:56,481,212...56,679,012
Ensembl chr18:59,802,443...59,992,100

BIN3

bridging integrator 3

acts_upstream_of_or_within
involved_in

(MGI:5517720|PMID:23872330)

PMID:23872330

GO_REF:0000107 MGI:5517720

NCBI chr 8:21,870,784...21,919,077
Ensembl chr 8:18,809,582...18,858,912

CACNA1S

calcium voltage-gated channel subunit alpha1 S

acts_upstream_of_or_within
involved_in

(MGI:66718|PMID:8143864)
(MGI:3630139|PMID:289331), (MGI:53207|PMID:8462749)

PMID:289331 PMID:8143864 PMID:8462749

GO_REF:0000107 MGI:3630139 MGI:53207 MGI:66718

NCBI chr 1:176,639,189...176,712,171
Ensembl chr 1:180,941,836...181,014,823

CAV2

caveolin 2

acts_upstream_of_or_within
involved_in

(MGI:3695802|PMID:17200204)

PMID:17200204

GO_REF:0000107 MGI:3695802

NCBI chr 7:108,254,074...108,480,716
Ensembl chr 7:121,168,579...121,177,415

DNER

delta/notch like EGF repeat containing

acts_upstream_of_or_within
involved_in

(MGI:3583881|PMID:15965470)

PMID:15965470

GO_REF:0000107 MGI:3583881

NCBI chr2B:116,604,193...116,963,026
Ensembl chr2B:235,409,108...235,642,161

GPX1

glutathione peroxidase 1

acts_upstream_of_or_within

(MGI:3662804|PMID:16962942)

PMID:16962942

MGI:3662804

NCBI chr 3:49,280,038...49,281,455
Ensembl chr 3:50,360,947...50,361,826

HOMER1

homer scaffold protein 1

acts_upstream_of_or_within
involved_in

(MGI:3784629|PMID:18268005)

PMID:18268005

GO_REF:0000107 MGI:3784629

NCBI chr 5:35,794,627...35,936,111
Ensembl chr 5:36,064,665...36,205,928

KLHL40

kelch like family member 40

acts_upstream_of_or_within
involved_in

(MGI:5586592|PMID:24960163)

MGI
InterPro

PMID:24960163

GO_REF:0000002 MGI:5586592

NCBI chr 3:42,592,977...42,600,100
Ensembl chr 3:43,657,128...43,664,055

KLHL41

kelch like family member 41

involved_in

InterPro

GO_REF:0000002

NCBI chr2B:56,778,475...56,798,317
Ensembl chr2B:174,248,884...174,265,508

LMOD3

leiomodin 3

involved_in

GO_REF:0000107

NCBI chr 3:69,042,870...69,058,704
Ensembl chr 3:70,410,288...70,424,702

LOC100989368

Kell metallo-endopeptidase (Kell blood group)

acts_upstream_of_or_within
involved_in

(MGI:5550316|PMID:24405768)

PMID:24405768

GO_REF:0000107 MGI:5550316

NCBI chr 7:134,897,567...135,237,214
Ensembl chr 7:147,423,103...147,443,895
Ensembl chr 7:147,423,103...147,443,895

MYOD1

myogenic differentiation 1

acts_upstream_of_or_within
involved_in

(MGI:3840749|PMID:19319192)

PMID:19319192

GO_REF:0000107 MGI:3840749

NCBI chr11:17,772,317...17,774,884
Ensembl chr11:17,456,124...17,458,690

MYOG

myogenin

acts_upstream_of_or_within
involved_in

(MGI:62381|PMID:8393145)

PMID:8393145

GO_REF:0000107 MGI:62381

NCBI chr 1:178,684,933...178,687,971
Ensembl chr 1:182,979,700...182,982,611

MYORG

myogenesis regulating glycosidase (putative)

acts_upstream_of_or_within
involved_in

(MGI:4422154|PMID:19706595)

PMID:19706595

GO_REF:0000107 MGI:4422154

NCBI chr 9:34,205,177...34,213,351
Ensembl chr 9:35,015,847...35,017,991

NFATC3

nuclear factor of activated T cells 3

acts_upstream_of_or_within

(MGI:1933051|PMID:11254352)

PMID:11254352

MGI:1933051

NCBI chr16:48,456,144...48,603,306
Ensembl chr16:67,888,806...67,996,274

P2RX2

purinergic receptor P2X 2

acts_upstream_of_or_within

(MGI:3766888|PMID:17706883)

PMID:17706883

MGI:3766888

NCBI chr12:129,969,793...129,974,399

PLEC

plectin

involved_in

GO_REF:0000107

NCBI chr 8:140,681,252...140,742,753
Ensembl chr 8:143,674,696...143,712,433

PPP3CA

protein phosphatase 3 catalytic subunit alpha

acts_upstream_of_or_within
involved_in

(MGI:3586394|PMID:16024798)

PMID:16024798

GO_REF:0000107 MGI:3586394

NCBI chr 4:93,447,095...93,770,339
Ensembl chr 4:104,113,520...104,435,394

PPP3CB

protein phosphatase 3 catalytic subunit beta

involved_in

GO_REF:0000107

NCBI chr10:69,984,241...70,043,352
Ensembl chr10:72,443,051...72,501,752

RCAN1

regulator of calcineurin 1

acts_upstream_of_or_within
involved_in

(MGI:3586394|PMID:16024798)

PMID:16024798

GO_REF:0000107 MGI:3586394

NCBI chr21:20,889,123...20,987,964
Ensembl chr21:34,258,355...34,267,025

RIPOR2

RHO family interacting cell polarization regulator 2

involved_in

InterPro

GO_REF:0000002

NCBI chr 6:24,642,239...24,768,074
Ensembl chr 6:24,973,412...25,204,745

RYR1

ryanodine receptor 1

involved_in

(MGI:3764002|PMID:18003898)

PMID:18003898

MGI:3764002

NCBI chr19:35,527,466...35,685,446
Ensembl chr19:44,106,036...44,256,327

SELENON

selenoprotein N

acts_upstream_of_or_within
involved_in

(MGI:5494499|PMID:23325319)

PMID:23325319

GO_REF:0000107 MGI:5494499

NCBI chr 1:25,058,907...25,076,817
Ensembl chr 1:26,127,125...26,141,745

SKI

SKI proto-oncogene

acts_upstream_of_or_within

(MGI:1095997|PMID:9284043)

PMID:9284043

MGI:1095997

NCBI chr 1:944,428...1,029,695
Ensembl chr 1:2,091,620...2,174,080

SMO

smoothened, frizzled class receptor

acts_upstream_of_or_within

(MGI:5438143|PMID:22987639)

PMID:22987639

MGI:5438143

NCBI chr 7:121,143,968...121,168,873
Ensembl chr 7:133,668,304...133,693,048

SPG11

SPG11 vesicle trafficking associated, spatacsin

acts_upstream_of_or_within
involved_in

(MGI:6141536|PMID:28237315)

PMID:28237315

GO_REF:0000107 MGI:6141536

NCBI chr15:23,519,311...23,620,532
Ensembl chr15:41,688,081...41,788,616

STAC3

SH3 and cysteine rich domain 3

acts_upstream_of_or_within
involved_in

(MGI:5508972|PMID:23626854)

PMID:23626854

GO_REF:0000107 MGI:5508972

NCBI chr12:31,674,537...31,683,917
Ensembl chr12:31,928,955...31,936,251

WNT10B

Wnt family member 10B

acts_upstream_of_or_within
involved_in

(MGI:3581945|PMID:15673614)

PMID:15673614

GO_REF:0000107 MGI:3581945

NCBI chr12:39,771,163...39,785,411
Ensembl chr12:40,659,106...40,665,734

X-linked Kx blood group

acts_upstream_of_or_within

(MGI:5550316|PMID:24405768)

PMID:24405768

MGI:5550316

NCBI chr X:30,136,046...30,182,541
Ensembl chr X:37,846,539...37,892,348

skeletal muscle fiber differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

KLHL40

kelch like family member 40

involved_in
acts_upstream_of_or_within

PMID:24361185 PMID:25940086

(MGI:5700633|PMID:25940086)
(MGI:5565628|PMID:24361185)

UniProt
MGI

MGI:5565628 MGI:5700633

NCBI chr 3:42,592,977...42,600,100
Ensembl chr 3:43,657,128...43,664,055

sonic hedgehog signaling molecule

acts_upstream_of_or_within
involved_in

(MGI:3621570|PMID:15238161)

PMID:15238161

GO_REF:0000107 MGI:3621570

NCBI chr 7:147,400,112...147,414,036
Ensembl chr 7:159,114,666...159,126,651

SIX4

SIX homeobox 4

involved_in

GO_REF:0000107

NCBI chr14:41,316,169...41,332,160
Ensembl chr14:59,580,587...59,594,014

skeletal muscle satellite cell commitment

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

PAX7

paired box 7

acts_upstream_of_or_within

(MGI:1889987|PMID:11030621)

PMID:11030621

MGI:1889987

NCBI chr 1:17,589,513...17,707,442
Ensembl chr 1:18,639,641...18,756,952

skeletal muscle satellite cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CDON

cell adhesion associated, oncogene regulated

acts_upstream_of_or_within
involved_in

(MGI:3522534|PMID:15572127)

PMID:15572127

GO_REF:0000107 MGI:3522534

NCBI chr11:120,772,160...120,877,529
Ensembl chr11:124,685,084...124,786,091

KLF5

Kruppel like factor 5

involved_in
acts_upstream_of_or_within

(MGI:5823533|PMID:27743478)

PMID:27743478

GO_REF:0000107 MGI:5823533

NCBI chr13:54,287,578...54,310,216

MEGF10

multiple EGF like domains 10

involved_in

GO_REF:0000107

NCBI chr 5:122,639,155...122,877,324
Ensembl chr 5:128,466,095...128,641,043

MYLK2

myosin light chain kinase 2

involved_in

GO_REF:0000107

NCBI chr20:28,113,024...28,128,142
Ensembl chr20:29,243,391...29,258,508

SELENON

selenoprotein N

acts_upstream_of_or_within
involved_in

(MGI:4936779|PMID:21131290)

PMID:21131290

GO_REF:0000107 MGI:4936779

NCBI chr 1:25,058,907...25,076,817
Ensembl chr 1:26,127,125...26,141,745

skeletal muscle tissue development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BVES

blood vessel epicardial substance

involved_in

GO_REF:0000107

NCBI chr 6:102,915,148...102,951,141
Ensembl chr 6:106,787,615...106,822,050

CACNA1S

calcium voltage-gated channel subunit alpha1 S

acts_upstream_of_or_within
involved_in

(MGI:52955|PMID:14300095), (MGI:56113|PMID:6500174), (MGI:63119|PMID:14300096), (MGI:76166|PMID:7635187)

PMID:6500174 PMID:7635187 PMID:14300095 PMID:14300096

GO_REF:0000107 MGI:52955 MGI:56113 MGI:63119 MGI:76166

NCBI chr 1:176,639,189...176,712,171
Ensembl chr 1:180,941,836...181,014,823

calsequestrin 1

NCBI chr 1:135,544,249...135,555,545
Ensembl chr 1:139,465,605...139,476,969

CAV1

caveolin 1

acts_upstream_of_or_within
involved_in

(MGI:3695802|PMID:17200204)

PMID:17200204

GO_REF:0000107 MGI:3695802

NCBI chr 7:108,497,125...108,533,090
Ensembl chr 7:121,193,424...121,229,655

CCNT2

cyclin T2

involved_in

GO_REF:0000107

NCBI chr2B:24,903,389...24,943,122
Ensembl chr2B:138,994,868...139,035,301

CDK5

cyclin dependent kinase 5

involved_in
acts_upstream_of_or_within

PMID:9191048 PMID:15208659

(MGI:892714|PMID:9191048)

RGD
Ensembl
MGI

GO_REF:0000107 MGI:892714 RGD:1598429

NCBI chr 7:142,640,630...142,644,785
Ensembl chr 7:154,793,344...154,797,499

CDON

cell adhesion associated, oncogene regulated

acts_upstream_of
involved_in

(MGI:3522534|PMID:15572127)

PMID:15572127

GO_REF:0000107 MGI:3522534

NCBI chr11:120,772,160...120,877,529
Ensembl chr11:124,685,084...124,786,091

CFL2

cofilin 2

involved_in

GO_REF:0000107

NCBI chr14:15,468,532...15,473,094
Ensembl chr14:33,655,744...33,659,473

CFLAR

CASP8 and FADD like apoptosis regulator

involved_in