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ONTOLOGY REPORT - ANNOTATIONS

Term:type II pneumocyte differentiation
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Accession:GO:0060510 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a type II pneumocyte. A type II pneumocyte is a surfactant secreting cell that contains abundant cytoplasm containing numerous lipid-rich multilamellar bodies.
Synonyms:exact_synonym: great alveolar cell differentiation
 related_synonym: granular pneumocyte differentiation;   large alveolar cell differentiation


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type II pneumocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aimp2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:3497919 (MGI:2665161|PMID:12819782)
GO_REF:0000107		 RGD
Ensembl		 PMID:12819782 GO_REF:0000107 MGI:2665161 NCBI chr12:10,701,194...10,710,772
Ensembl chr12:10,701,194...10,710,769 		JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO (MGI:3577664|PMID:15531758) RGD PMID:15531758 MGI:3577664 NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Fndc3b fibronectin type III domain containing 3B acts_upstream_of_or_within ISO MGI:4822558 (MGI:5298325|PMID:21704616) RGD PMID:21704616 MGI:5298325 NCBI chr 2:110,311,439...110,617,504
Ensembl chr 2:110,312,694...110,547,830 		JBrowse link
G Gata6 GATA binding protein 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:108067 (MGI:3695537|PMID:17164424)		 Ensembl
RGD		 PMID:17164424 GO_REF:0000107 MGI:3695537 NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532 		JBrowse link
G Igf1 insulin-like growth factor 1 acts_upstream_of_or_within ISO MGI:1926485 (MGI:3640953|PMID:16691571) RGD PMID:16691571 MGI:3640953 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Nfib nuclear factor I/B involved_in ISS
ISO		 GO_REF:0000024
(MGI:5049839|PMID:21513708)		 UniProt
RGD		 PMID:21513708 GO_REF:0000024 MGI:5049839 NCBI chr 5:96,759,208...96,974,001
Ensembl chr 5:96,764,653...96,975,479 		JBrowse link
G Nkx2-1 NK2 homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:107516 (MGI:3695537|PMID:17164424)		 Ensembl
RGD		 PMID:17164424 GO_REF:0000107 MGI:3695537 NCBI chr 6:73,996,601...74,001,483
Ensembl chr 6:73,996,601...73,999,791 		JBrowse link
G Rbbp9 RB binding protein 9, serine hydrolase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:6501918|PMID:32484881)
GO_REF:0000107		 RGD
Ensembl		 PMID:32484881 GO_REF:0000107 MGI:6501918 NCBI chr 3:131,925,095...131,939,042
Ensembl chr 3:131,925,341...131,932,156 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19553
    cellular process 18233
      cellular developmental process 4642
        cell differentiation 4641
          lung cell differentiation 41
            lung epithelial cell differentiation 41
              lung secretory cell differentiation 14
                type II pneumocyte differentiation 8
Path 2
Term Annotations click to browse term
  biological_process 19553
    developmental process 6909
      anatomical structure development 6435
        multicellular organism development 5184
          system development 4463
            respiratory system development 317
              lung development 281
                lung epithelium development 61
                  lung epithelial cell differentiation 41
                    lung secretory cell differentiation 14
                      type II pneumocyte differentiation 8
paths to the root