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ONTOLOGY REPORT - ANNOTATIONS

Term:type II pneumocyte differentiation
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Accession:GO:0060510 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a type II pneumocyte. A type II pneumocyte is a surfactant secreting cell that contains abundant cytoplasm containing numerous lipid-rich multilamellar bodies.
Synonyms:exact_synonym: great alveolar cell differentiation
 related_synonym: granular pneumocyte differentiation;   large alveolar cell differentiation


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type II pneumocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aimp2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3497919 (PMID:12819782) 		Ensembl
RGD		 PMID:12819782 GO_REF:0000107 NCBI chr12:15,814,854...15,824,432
Ensembl chr12:15,814,878...15,824,431 		JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:15531758) 		Ensembl
RGD		 PMID:15531758 GO_REF:0000107 NCBI chr 2:52,533,939...52,610,980
Ensembl chr 2:52,533,939...52,610,980 		JBrowse link
G Fndc3b fibronectin type III domain containing 3B acts_upstream_of_or_within ISO MGI:4822558 (PMID:21704616) RGD PMID:21704616 NCBI chr 2:112,240,108...112,546,113
Ensembl chr 2:112,243,202...112,546,306 		JBrowse link
G Gata6 GATA binding protein 6 acts_upstream_of_or_within ISO MGI:108067 (PMID:17164424) RGD PMID:17164424 NCBI chr18:2,460,909...2,492,322
Ensembl chr18:2,458,253...2,492,322 		JBrowse link
G Igf1 insulin-like growth factor 1 acts_upstream_of_or_within ISO MGI:1926485 (PMID:16691571) RGD PMID:16691571 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764 		JBrowse link
G Nfib nuclear factor I/B involved_in ISO (PMID:21513708) RGD PMID:21513708 NCBI chr 5:101,805,168...102,020,618
Ensembl chr 5:101,805,168...102,019,945 		JBrowse link
G Nkx2-1 NK2 homeobox 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:107516 (PMID:17164424) 		Ensembl
RGD		 PMID:17164424 GO_REF:0000107 NCBI chr 6:79,731,677...79,735,952
Ensembl chr 6:79,731,677...79,736,441 		JBrowse link
G Rbbp9 RB binding protein 9, serine hydrolase acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:32484881) 		Ensembl
RGD		 PMID:32484881 GO_REF:0000107 NCBI chr 3:152,378,426...152,392,370
Ensembl chr 3:152,378,699...152,385,489 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19315
    cellular process 18484
      cellular developmental process 4933
        cell differentiation 4932
          lung cell differentiation 35
            lung epithelial cell differentiation 35
              lung secretory cell differentiation 15
                type II pneumocyte differentiation 8
Path 2
Term Annotations click to browse term
  biological_process 19315
    developmental process 7255
      anatomical structure development 6748
        multicellular organism development 5415
          system development 4702
            respiratory system development 320
              lung development 283
                lung epithelium development 55
                  lung epithelial cell differentiation 35
                    lung secretory cell differentiation 15
                      type II pneumocyte differentiation 8
paths to the root