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ONTOLOGY REPORT - ANNOTATIONS

Term:type I pneumocyte differentiation
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Accession:GO:0060509 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a type I pneumocyte. A type I pneumocyte is a flattened cell with greatly attenuated cytoplasm and a paucity of organelles.
Synonyms:exact_synonym: membranous pneumocyte differentiation
 related_synonym: small alveolar cell differentiation;   squamous alveolar cell differentiation


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type I pneumocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Creb1 cAMP responsive element binding protein 1 acts_upstream_of_or_within ISO MGI:4999627 (MGI:4950818|PMID:21408140) RGD PMID:21408140 MGI:4950818 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Igf1 insulin-like growth factor 1 acts_upstream_of_or_within ISO MGI:1926485 (MGI:3640953|PMID:16691571) RGD PMID:16691571 MGI:3640953 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Klf2 KLF transcription factor 2 acts_upstream_of_or_within ISO (MGI:5297307|PMID:22001906) RGD PMID:22001906 MGI:5297307 NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944 		JBrowse link
G Kras KRAS proto-oncogene, GTPase acts_upstream_of ISO (MGI:5523405|PMID:24058167) RGD PMID:24058167 MGI:5523405 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Lta4h leukotriene A4 hydrolase IEP RGD PMID:15805137 RGD:2316585 NCBI chr 7:27,969,796...28,001,600
Ensembl chr 7:27,969,789...28,001,600 		JBrowse link
G Ncor2 nuclear receptor co-repressor 2 acts_upstream_of_or_within ISO MGI:3829987|MGI:98742|MGI:98743 (MGI:5297307|PMID:22001906) RGD PMID:22001906 MGI:5297307 NCBI chr12:31,466,418...31,628,319
Ensembl chr12:31,466,412...31,628,319 		JBrowse link
G Nfib nuclear factor I/B involved_in ISS
ISO		 GO_REF:0000024
(MGI:5049839|PMID:21513708)		 UniProt
RGD		 PMID:21513708 GO_REF:0000024 MGI:5049839 NCBI chr 5:96,759,208...96,974,001
Ensembl chr 5:96,764,653...96,975,479 		JBrowse link
G Sox9 SRY-box transcription factor 9 acts_upstream_of ISO MGI:2385468 (MGI:5523405|PMID:24058167) RGD PMID:24058167 MGI:5523405 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Thra thyroid hormone receptor alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1337080|MGI:98743 (MGI:5297307|PMID:22001906)		 Ensembl
RGD		 PMID:22001906 GO_REF:0000107 MGI:5297307 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936 		JBrowse link
G Thrb thyroid hormone receptor beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1337080|MGI:98742 (MGI:5297307|PMID:22001906)		 Ensembl
RGD		 PMID:22001906 GO_REF:0000107 MGI:5297307 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19553
    cellular process 18233
      cellular developmental process 4642
        cell differentiation 4641
          lung cell differentiation 41
            lung epithelial cell differentiation 41
              type I pneumocyte differentiation 10
Path 2
Term Annotations click to browse term
  biological_process 19553
    developmental process 6909
      anatomical structure development 6435
        multicellular organism development 5184
          system development 4463
            respiratory system development 317
              lung development 281
                lung epithelium development 61
                  lung epithelial cell differentiation 41
                    type I pneumocyte differentiation 10
paths to the root