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ONTOLOGY REPORT - ANNOTATIONS


Term:lung cell differentiation
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Accession:GO:0060479 term browser browse the term
Definition:The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate.
Synonyms:exact_synonym: pulmonary cell differentiation


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lung cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:19805295) Ensembl
MGI
PMID:19805295 GO_REF:0000107 NCBI chrNW_004936473:29,999,542...30,034,610
Ensembl chrNW_004936473:29,999,562...30,038,293
JBrowse link
club cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata6 GATA binding protein 6 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17164424) Ensembl
MGI
PMID:17164424 GO_REF:0000107 NCBI chrNW_004936550:1,814,336...1,844,399
Ensembl chrNW_004936550:1,814,336...1,844,399
JBrowse link
G Nfib nuclear factor I B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936539:7,763,036...8,185,001
Ensembl chrNW_004936539:7,769,413...7,985,316
JBrowse link
G Nkx2-1 NK2 homeobox 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17164424) Ensembl
MGI
PMID:17164424 GO_REF:0000107 NCBI chrNW_004936494:10,517,488...10,520,567
Ensembl chrNW_004936494:10,517,488...10,520,566
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22797898) Ensembl
MGI
PMID:22797898 GO_REF:0000107 NCBI chrNW_004936477:3,354,336...3,445,248
Ensembl chrNW_004936477:3,349,627...3,461,797
JBrowse link
lung ciliated cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfib nuclear factor I B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936539:7,763,036...8,185,001
Ensembl chrNW_004936539:7,769,413...7,985,316
JBrowse link
lung epithelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col6a1 collagen type VI alpha 1 chain acts_upstream_of_or_within ISO (PMID:31837950) MGI PMID:31837950 NCBI chrNW_004936778:515,600...530,828 JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of
involved_in
ISO
IEA
(PMID:16040629) MGI
Ensembl
PMID:16040629 GO_REF:0000107 NCBI chrNW_004936473:29,999,542...30,034,610
Ensembl chrNW_004936473:29,999,562...30,038,293
JBrowse link
G Foxa1 forkhead box A1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15668254) Ensembl
MGI
PMID:15668254 GO_REF:0000107 NCBI chrNW_004936494:11,529,546...11,535,224
Ensembl chrNW_004936494:11,529,546...11,535,224
JBrowse link
G Foxa2 forkhead box A2 acts_upstream_of_or_within ISO (PMID:15668254) MGI PMID:15668254 NCBI chrNW_004936620:2,966,341...2,969,349
Ensembl chrNW_004936620:2,966,341...2,969,349
JBrowse link
G Grhl2 grainyhead like transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936470:41,856,683...41,961,666
Ensembl chrNW_004936470:41,859,035...42,002,844
JBrowse link
G LOC101971285 7-dehydrocholesterol reductase acts_upstream_of_or_within ISO (PMID:15005800) MGI PMID:15005800 NCBI chrNW_004936794:1,432,379...1,468,966 JBrowse link
G Ppp3r1 protein phosphatase 3 regulatory subunit B, alpha involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16998587) Ensembl
MGI
PMID:16998587 GO_REF:0000107 NCBI chrNW_004936491:12,623,931...12,654,463
Ensembl chrNW_004936491:12,623,349...12,654,502
Ensembl chrNW_004936491:12,623,349...12,654,502
JBrowse link
G Pthlh parathyroid hormone like hormone acts_upstream_of_or_within ISO (PMID:15162506) MGI PMID:15162506 NCBI chrNW_004936760:197,525...209,212
Ensembl chrNW_004936760:197,525...209,518
JBrowse link
G Sav1 salvador family WW domain containing protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:18369314) Ensembl
MGI
PMID:18369314 GO_REF:0000107 NCBI chrNW_004936495:14,955,234...14,977,720
Ensembl chrNW_004936495:14,954,542...14,976,580
JBrowse link
G Sox9 SRY-box transcription factor 9 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:24191021) MGI
Ensembl
PMID:24191021 GO_REF:0000107 NCBI chrNW_004936655:1,849,044...1,852,648
Ensembl chrNW_004936655:1,847,272...1,852,705
JBrowse link
G Tmem38b transmembrane protein 38B involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:19515693) Ensembl
MGI
PMID:19515693 GO_REF:0000107 NCBI chrNW_004936559:6,501,890...6,553,446
Ensembl chrNW_004936559:6,500,190...6,553,513
JBrowse link
G Yap1 Yes1 associated transcriptional regulator acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:25043473) MGI
Ensembl
PMID:25043473 GO_REF:0000107 NCBI chrNW_004936551:5,638,383...5,740,523
Ensembl chrNW_004936551:5,634,751...5,740,567
JBrowse link
lung goblet cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agr2 anterior gradient 2, protein disulphide isomerase family member involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22675208) Ensembl
MGI
PMID:22675208 GO_REF:0000107 NCBI chrNW_004936546:3,316,622...3,328,317
Ensembl chrNW_004936546:3,315,543...3,328,369
JBrowse link
G Hoxa5 homeobox A5 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17003488) Ensembl
MGI
PMID:17003488 GO_REF:0000107 NCBI chrNW_004936478:3,768,757...3,771,850
Ensembl chrNW_004936478:3,769,258...3,771,840
JBrowse link
G Spdef SAM pointed domain containing ETS transcription factor involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17347682) Ensembl
MGI
PMID:17347682 GO_REF:0000107 NCBI chrNW_004936476:24,563,591...24,571,739
Ensembl chrNW_004936476:24,563,591...24,570,692
JBrowse link
lung neuroendocrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl1 achaete-scute family bHLH transcription factor 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:9126746) MGI
Ensembl
PMID:9126746 GO_REF:0000107 NCBI chrNW_004936492:11,315,929...11,317,166
Ensembl chrNW_004936492:11,316,417...11,317,166
JBrowse link
lung secretory cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp1 forkhead box P1 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chrNW_004936603:2,631,781...3,146,104
Ensembl chrNW_004936603:2,632,274...2,830,324
JBrowse link
G Foxp4 forkhead box P4 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chrNW_004936476:18,314,108...18,346,149
Ensembl chrNW_004936476:18,313,951...18,346,199
JBrowse link
negative regulation of lung goblet cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp1 forkhead box P1 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chrNW_004936603:2,631,781...3,146,104
Ensembl chrNW_004936603:2,632,274...2,830,324
JBrowse link
G Foxp4 forkhead box P4 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chrNW_004936476:18,314,108...18,346,149
Ensembl chrNW_004936476:18,313,951...18,346,199
JBrowse link
positive regulation of lung ciliated cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxj1 forkhead box J1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936594:1,284,799...1,288,898
Ensembl chrNW_004936594:1,284,781...1,289,361
JBrowse link
G Tp73 tumor protein p73 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936737:171,894...211,464
Ensembl chrNW_004936737:172,467...211,464
JBrowse link
regulation of lung goblet cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp1 forkhead box P1 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chrNW_004936603:2,631,781...3,146,104
Ensembl chrNW_004936603:2,632,274...2,830,324
JBrowse link
G Foxp4 forkhead box P4 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chrNW_004936476:18,314,108...18,346,149
Ensembl chrNW_004936476:18,313,951...18,346,199
JBrowse link
type I pneumocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Creb1 cAMP responsive element binding protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21408140) Ensembl
MGI
PMID:21408140 GO_REF:0000107 NCBI chrNW_004936631:3,721,307...3,785,346
Ensembl chrNW_004936631:3,721,313...3,780,892
JBrowse link
G Igf1 insulin like growth factor 1 acts_upstream_of_or_within ISO (PMID:16691571) MGI PMID:16691571 NCBI chrNW_004936492:11,709,623...11,784,028
Ensembl chrNW_004936492:11,709,222...11,778,351
JBrowse link
G Kras KRAS proto-oncogene, GTPase involved_in
acts_upstream_of
IEA
ISO
(PMID:24058167) Ensembl
MGI
PMID:24058167 GO_REF:0000107 NCBI chrNW_004936548:2,078,568...2,113,877
Ensembl chrNW_004936548:2,079,036...2,110,523
JBrowse link
G Lta4h leukotriene A4 hydrolase ISO RGD PMID:15805137 RGD:2316585 NCBI chrNW_004936507:12,082,373...12,120,078
Ensembl chrNW_004936507:12,082,068...12,120,091
JBrowse link
G Ncor2 nuclear receptor corepressor 2 acts_upstream_of_or_within ISO (PMID:22001906) MGI PMID:22001906 NCBI chrNW_004936558:658,723...775,263
Ensembl chrNW_004936558:677,610...775,288
JBrowse link
G Nfib nuclear factor I B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936539:7,763,036...8,185,001
Ensembl chrNW_004936539:7,769,413...7,985,316
JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in
acts_upstream_of
IEA
ISO
(PMID:24058167) Ensembl
MGI
PMID:24058167 GO_REF:0000107 NCBI chrNW_004936655:1,849,044...1,852,648
Ensembl chrNW_004936655:1,847,272...1,852,705
JBrowse link
G Thra thyroid hormone receptor alpha involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22001906) Ensembl
MGI
PMID:22001906 GO_REF:0000107 NCBI chrNW_004936490:15,188,341...15,206,032
Ensembl chrNW_004936490:15,193,150...15,206,784
JBrowse link
G Thrb thyroid hormone receptor beta involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22001906) Ensembl
MGI
PMID:22001906 GO_REF:0000107 NCBI chrNW_004936473:15,766,214...15,986,389
Ensembl chrNW_004936473:15,770,146...15,986,561
JBrowse link
type II pneumocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aimp2 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 acts_upstream_of_or_within ISO (PMID:12819782) MGI PMID:12819782 NCBI chrNW_004936750:430,780...439,247 JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:15531758) MGI
Ensembl
PMID:15531758 GO_REF:0000107 NCBI chrNW_004936480:18,114,231...18,195,884
Ensembl chrNW_004936480:18,114,204...18,195,898
JBrowse link
G Fndc3b fibronectin type III domain containing 3B acts_upstream_of_or_within ISO (PMID:21704616) MGI PMID:21704616 NCBI chrNW_004936593:311,245...638,625
Ensembl chrNW_004936593:311,245...566,800
JBrowse link
G Gata6 GATA binding protein 6 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17164424) Ensembl
MGI
PMID:17164424 GO_REF:0000107 NCBI chrNW_004936550:1,814,336...1,844,399
Ensembl chrNW_004936550:1,814,336...1,844,399
JBrowse link
G Igf1 insulin like growth factor 1 acts_upstream_of_or_within ISO (PMID:16691571) MGI PMID:16691571 NCBI chrNW_004936492:11,709,623...11,784,028
Ensembl chrNW_004936492:11,709,222...11,778,351
JBrowse link
G Nfib nuclear factor I B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936539:7,763,036...8,185,001
Ensembl chrNW_004936539:7,769,413...7,985,316
JBrowse link
G Nkx2-1 NK2 homeobox 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17164424) Ensembl
MGI
PMID:17164424 GO_REF:0000107 NCBI chrNW_004936494:10,517,488...10,520,567
Ensembl chrNW_004936494:10,517,488...10,520,566
JBrowse link
G Rbbp9 RB binding protein 9, serine hydrolase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:32484881) Ensembl
MGI
PMID:32484881 GO_REF:0000107 NCBI chrNW_004936485:1,787,048...1,796,233
Ensembl chrNW_004936485:1,787,028...1,798,277
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17407
    cellular process 17010
      cellular developmental process 4339
        cell differentiation 4338
          lung cell differentiation 35
            lung basal cell differentiation 0
            lung epithelial cell differentiation + 35
Path 2
Term Annotations click to browse term
  biological_process 17407
    developmental process 6423
      anatomical structure development 6038
        multicellular organism development 4887
          system development 4253
            respiratory system development 300
              lung development 264
                lung cell differentiation 35
                  lung basal cell differentiation 0
                  lung epithelial cell differentiation + 35
paths to the root