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ONTOLOGY REPORT - ANNOTATIONS


Term:lung cell differentiation
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Accession:GO:0060479 term browser browse the term
Definition:The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate.
Synonyms:exact_synonym: pulmonary cell differentiation



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lung cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin beta 1 acts_upstream_of_or_within IMP (PMID:19805295) MGI PMID:19805295 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
JBrowse link
club cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata6 GATA binding protein 6 acts_upstream_of_or_within IGI (PMID:17164424) MGI PMID:17164424 NCBI chr18:11,052,510...11,085,636
Ensembl chr18:11,052,064...11,085,635
JBrowse link
G Nfib nuclear factor I/B involved_in IMP (PMID:21513708) UniProt PMID:21513708 NCBI chr 4:82,208,410...82,424,988
Ensembl chr 4:82,208,410...82,623,987
JBrowse link
G Nkx2-1 NK2 homeobox 1 acts_upstream_of_or_within IGI (PMID:17164424) MGI PMID:17164424 NCBI chr12:56,578,741...56,583,570
Ensembl chr12:56,578,743...56,583,693
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region acts_upstream_of_or_within IMP (PMID:22797898) MGI PMID:22797898 NCBI chr 5:53,713,121...53,814,787
Ensembl chr 5:53,623,494...53,814,704
JBrowse link
lung ciliated cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfib nuclear factor I/B involved_in IMP (PMID:21513708) UniProt PMID:21513708 NCBI chr 4:82,208,410...82,424,988
Ensembl chr 4:82,208,410...82,623,987
JBrowse link
lung epithelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col6a1 collagen, type VI, alpha 1 acts_upstream_of_or_within IMP (PMID:31837950) MGI PMID:31837950 NCBI chr10:76,544,626...76,561,869
Ensembl chr10:76,544,626...76,562,002
JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of IMP (PMID:16040629) MGI PMID:16040629 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase acts_upstream_of_or_within IMP (PMID:15005800) MGI PMID:15005800 NCBI chr 7:143,376,827...143,402,147
Ensembl chr 7:143,376,882...143,402,147
JBrowse link
G Foxa1 forkhead box A1 acts_upstream_of_or_within IGI (PMID:15668254) MGI PMID:15668254 NCBI chr12:57,585,750...57,594,815
Ensembl chr12:57,587,414...57,593,702
JBrowse link
G Foxa2 forkhead box A2 acts_upstream_of_or_within IGI (PMID:15668254) MGI PMID:15668254 NCBI chr 2:147,884,797...147,888,889
Ensembl chr 2:147,884,797...147,888,889
JBrowse link
G Grhl2 grainyhead like transcription factor 2 involved_in IMP (PMID:22955271) UniProt PMID:22955271 NCBI chr15:37,233,065...37,363,813
Ensembl chr15:37,233,280...37,363,813
JBrowse link
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I) acts_upstream_of_or_within IMP (PMID:16998587) MGI PMID:16998587 NCBI chr11:17,109,298...17,150,380
Ensembl chr11:17,109,263...17,150,375
JBrowse link
G Pthlh parathyroid hormone-like peptide acts_upstream_of_or_within IMP (PMID:15162506) MGI PMID:15162506 NCBI chr 6:147,153,607...147,165,511
Ensembl chr 6:147,153,599...147,165,681
JBrowse link
G Sav1 salvador family WW domain containing 1 acts_upstream_of_or_within IMP (PMID:18369314) MGI PMID:18369314 NCBI chr12:70,011,786...70,033,864
Ensembl chr12:70,011,786...70,033,776
JBrowse link
G Sox9 SRY (sex determining region Y)-box 9 acts_upstream_of_or_within IMP (PMID:24191021) MGI PMID:24191021 NCBI chr11:112,673,036...112,678,583
Ensembl chr11:112,673,050...112,678,586
JBrowse link
G Tmem38b transmembrane protein 38B acts_upstream_of_or_within IMP (PMID:19515693) MGI PMID:19515693 NCBI chr 4:53,825,988...53,862,019
Ensembl chr 4:53,826,045...53,862,019
JBrowse link
G Yap1 yes-associated protein 1 acts_upstream_of_or_within IMP (PMID:25043473) MGI PMID:25043473 NCBI chr 9:7,932,000...8,004,890
Ensembl chr 9:7,932,000...8,004,597
JBrowse link
lung goblet cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agr2 anterior gradient 2 acts_upstream_of_or_within IDA (PMID:22675208) MGI PMID:22675208 NCBI chr12:36,042,924...36,054,080
Ensembl chr12:36,042,906...36,054,086
JBrowse link
G Hoxa5 homeobox A5 acts_upstream_of_or_within IMP (PMID:17003488) MGI PMID:17003488 NCBI chr 6:52,178,768...52,181,437
Ensembl chr 6:52,178,734...52,181,567
JBrowse link
G Spdef SAM pointed domain containing ets transcription factor acts_upstream_of_or_within IDA (PMID:17347682) MGI PMID:17347682 NCBI chr17:27,933,416...27,949,977
Ensembl chr17:27,933,326...27,947,929
JBrowse link
lung neuroendocrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl1 achaete-scute family bHLH transcription factor 1 acts_upstream_of_or_within IMP (PMID:9126746) MGI PMID:9126746 NCBI chr10:87,326,681...87,329,522
Ensembl chr10:87,326,681...87,329,522
JBrowse link
lung secretory cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp1 forkhead box P1 acts_upstream_of_or_within IGI (PMID:22675208) MGI PMID:22675208 NCBI chr 6:98,902,303...99,510,587
Ensembl chr 6:98,902,299...99,499,682
JBrowse link
G Foxp4 forkhead box P4 acts_upstream_of_or_within IGI (PMID:22675208) MGI PMID:22675208 NCBI chr17:48,178,058...48,235,401
Ensembl chr17:48,178,058...48,235,570
JBrowse link
negative regulation of lung goblet cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp1 forkhead box P1 acts_upstream_of_or_within IGI (PMID:22675208) MGI PMID:22675208 NCBI chr 6:98,902,303...99,510,587
Ensembl chr 6:98,902,299...99,499,682
JBrowse link
G Foxp4 forkhead box P4 acts_upstream_of_or_within IGI (PMID:22675208) MGI PMID:22675208 NCBI chr17:48,178,058...48,235,401
Ensembl chr17:48,178,058...48,235,570
JBrowse link
positive regulation of lung ciliated cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxj1 forkhead box J1 involved_in IEA
ISO
Ensembl
GO_Central
GO_REF:0000107 GO_REF:0000119 NCBI chr11:116,221,530...116,226,331
Ensembl chr11:116,221,530...116,226,225
JBrowse link
G Trp73 transformation related protein 73 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 4:154,140,706...154,224,332
Ensembl chr 4:154,140,706...154,224,665
JBrowse link
regulation of lung goblet cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp1 forkhead box P1 acts_upstream_of_or_within IGI (PMID:22675208) MGI PMID:22675208 NCBI chr 6:98,902,303...99,510,587
Ensembl chr 6:98,902,299...99,499,682
JBrowse link
G Foxp4 forkhead box P4 acts_upstream_of_or_within IGI (PMID:22675208) MGI PMID:22675208 NCBI chr17:48,178,058...48,235,401
Ensembl chr17:48,178,058...48,235,570
JBrowse link
type I pneumocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Creb1 cAMP responsive element binding protein 1 acts_upstream_of_or_within IMP (PMID:21408140) MGI PMID:21408140 NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707
JBrowse link
G Igf1 insulin-like growth factor 1 acts_upstream_of_or_within IMP (PMID:16691571) MGI PMID:16691571 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904
JBrowse link
G Klf2 Kruppel-like transcription factor 2 (lung) acts_upstream_of_or_within IMP (PMID:22001906) MGI PMID:22001906 NCBI chr 8:73,072,906...73,075,498
Ensembl chr 8:73,072,877...73,075,500
JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog acts_upstream_of IDA (PMID:24058167) MGI PMID:24058167 NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965
JBrowse link
G Lta4h leukotriene A4 hydrolase involved_in ISO
IEA
RGD
Ensembl
PMID:15805137 GO_REF:0000107 RGD:2316585 NCBI chr10:93,289,258...93,320,758
Ensembl chr10:93,289,273...93,320,737
JBrowse link
G Ncor2 nuclear receptor co-repressor 2 acts_upstream_of_or_within IMP
IGI
(PMID:22001906) MGI PMID:22001906 NCBI chr 5:125,094,217...125,256,302
Ensembl chr 5:125,094,217...125,256,283
JBrowse link
G Nfib nuclear factor I/B involved_in IMP (PMID:21513708) UniProt PMID:21513708 NCBI chr 4:82,208,410...82,424,988
Ensembl chr 4:82,208,410...82,623,987
JBrowse link
G Sox9 SRY (sex determining region Y)-box 9 acts_upstream_of IMP (PMID:24058167) MGI PMID:24058167 NCBI chr11:112,673,036...112,678,583
Ensembl chr11:112,673,050...112,678,586
JBrowse link
G Thra thyroid hormone receptor alpha acts_upstream_of_or_within IGI (PMID:22001906) MGI PMID:22001906 NCBI chr11:98,631,539...98,659,832
Ensembl chr11:98,631,464...98,659,832
JBrowse link
G Thrb thyroid hormone receptor beta acts_upstream_of_or_within IGI (PMID:22001906) MGI PMID:22001906 NCBI chr14:4,429,599...4,810,538
Ensembl chr14:4,431,611...4,809,435
JBrowse link
type II pneumocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aimp2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 acts_upstream_of_or_within IMP (PMID:12819782) MGI PMID:12819782 NCBI chr 5:143,839,522...143,846,657
Ensembl chr 5:143,839,522...143,846,665
JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within IDA (PMID:15531758) MGI PMID:15531758 NCBI chr13:118,851,199...118,928,651
Ensembl chr13:118,806,327...118,928,651
JBrowse link
G Fndc3b fibronectin type III domain containing 3B acts_upstream_of_or_within IMP (PMID:21704616) MGI PMID:21704616 NCBI chr 3:27,470,284...27,765,469
Ensembl chr 3:27,470,311...27,765,456
JBrowse link
G Gata6 GATA binding protein 6 acts_upstream_of_or_within IGI (PMID:17164424) MGI PMID:17164424 NCBI chr18:11,052,510...11,085,636
Ensembl chr18:11,052,064...11,085,635
JBrowse link
G Igf1 insulin-like growth factor 1 acts_upstream_of_or_within IMP (PMID:16691571) MGI PMID:16691571 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904
JBrowse link
G Nfib nuclear factor I/B involved_in IMP (PMID:21513708) UniProt PMID:21513708 NCBI chr 4:82,208,410...82,424,988
Ensembl chr 4:82,208,410...82,623,987
JBrowse link
G Nkx2-1 NK2 homeobox 1 acts_upstream_of_or_within IGI (PMID:17164424) MGI PMID:17164424 NCBI chr12:56,578,741...56,583,570
Ensembl chr12:56,578,743...56,583,693
JBrowse link
G Rbbp9 retinoblastoma binding protein 9, serine hydrolase acts_upstream_of_or_within IDA (PMID:32484881) MGI PMID:32484881 NCBI chr 2:144,384,185...144,392,779
Ensembl chr 2:144,384,185...144,392,789
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28633
    cellular process 18391
      cellular developmental process 5152
        cell differentiation 5151
          lung cell differentiation 36
            lung basal cell differentiation 0
            lung epithelial cell differentiation + 36
Path 2
Term Annotations click to browse term
  biological_process 28633
    developmental process 7498
      anatomical structure development 6968
        multicellular organism development 5545
          system development 4769
            respiratory system development 321
              lung development 285
                lung cell differentiation 36
                  lung basal cell differentiation 0
                  lung epithelial cell differentiation + 36
paths to the root