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ONTOLOGY REPORT - ANNOTATIONS


Term:lung cell differentiation
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Accession:GO:0060479 term browser browse the term
Definition:The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate.
Synonyms:exact_synonym: pulmonary cell differentiation


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lung cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTNNB1 catenin beta 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:19805295) Ensembl
MGI
PMID:19805295 GO_REF:0000107 NCBI chr22:2,679,488...2,725,034
Ensembl chr22:2,684,022...2,723,949
JBrowse link
club cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GATA6 GATA binding protein 6 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:17164424) MGI
Ensembl
PMID:17164424 GO_REF:0000107 NCBI chr18:58,312,328...58,345,472
Ensembl chr18:58,311,482...58,343,746
JBrowse link
G LOC103219433 nuclear factor 1 B-type involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:65,043,819...65,487,832
Ensembl chr12:65,256,407...65,481,485
JBrowse link
G NKX2-1 NK2 homeobox 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:17164424) MGI
Ensembl
PMID:17164424 GO_REF:0000107 NCBI chr24:13,274,118...13,317,533
Ensembl chr24:13,310,846...13,317,056
JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region acts_upstream_of_or_within ISO (PMID:22797898) MGI PMID:22797898 NCBI chr27:23,911,084...24,023,856 JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region involved_in IEA Ensembl GO_REF:0000107 Ensembl chr27:23,910,533...23,921,725 JBrowse link
lung ciliated cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC103219433 nuclear factor 1 B-type involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:65,043,819...65,487,832
Ensembl chr12:65,256,407...65,481,485
JBrowse link
lung epithelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL6A1 collagen type VI alpha 1 chain acts_upstream_of_or_within ISO (PMID:31837950) MGI PMID:31837950 NCBI chr 2:89,608,525...89,649,823 JBrowse link
G CTNNB1 catenin beta 1 involved_in
acts_upstream_of
IEA
ISO
(PMID:16040629) Ensembl
MGI
PMID:16040629 GO_REF:0000107 NCBI chr22:2,679,488...2,725,034
Ensembl chr22:2,684,022...2,723,949
JBrowse link
G DHCR7 7-dehydrocholesterol reductase acts_upstream_of_or_within ISO (PMID:15005800) MGI PMID:15005800 NCBI chr 1:3,243,263...3,257,332
Ensembl chr 1:3,243,313...3,257,487
JBrowse link
G FOXA1 forkhead box A1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15668254) Ensembl
MGI
PMID:15668254 GO_REF:0000107 NCBI chr24:14,397,759...14,403,078
Ensembl chr24:14,396,702...14,403,094
JBrowse link
G FOXA2 forkhead box A2 acts_upstream_of_or_within ISO (PMID:15668254) MGI PMID:15668254 NCBI chr 2:51,577,127...51,585,168
Ensembl chr 2:51,577,833...51,580,297
JBrowse link
G GRHL2 grainyhead like transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:96,340,459...96,526,366
Ensembl chr 8:96,342,189...96,526,363
JBrowse link
G PPP3R1 protein phosphatase 3 regulatory subunit B, alpha acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:16998587) MGI
Ensembl
PMID:16998587 GO_REF:0000107 NCBI chr14:38,832,976...38,907,425
Ensembl chr14:38,832,809...38,905,321
JBrowse link
G PTHLH parathyroid hormone like hormone acts_upstream_of_or_within ISO (PMID:15162506) MGI PMID:15162506 NCBI chr11:27,682,300...27,694,808
Ensembl chr11:27,682,338...27,694,898
JBrowse link
G SAV1 salvador family WW domain containing protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:18369314) Ensembl
MGI
PMID:18369314 GO_REF:0000107 NCBI chr24:27,710,256...27,747,638
Ensembl chr24:27,711,970...27,747,647
JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:24191021) Ensembl
MGI
PMID:24191021 GO_REF:0000107 NCBI chr16:49,519,749...49,523,967
Ensembl chr16:49,518,185...49,523,898
JBrowse link
G TMEM38B transmembrane protein 38B involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:19515693) Ensembl
MGI
PMID:19515693 GO_REF:0000107 NCBI chr12:33,759,311...33,840,357
Ensembl chr12:33,759,157...33,840,009
JBrowse link
G YAP1 Yes1 associated transcriptional regulator acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:25043473) MGI
Ensembl
PMID:25043473 GO_REF:0000107 NCBI chr 1:93,479,478...93,605,340
Ensembl chr 1:93,479,135...93,606,808
JBrowse link
lung goblet cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGR2 anterior gradient 2, protein disulphide isomerase family member involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22675208) Ensembl
MGI
PMID:22675208 GO_REF:0000107 NCBI chr21:41,311,250...41,324,806
Ensembl chr21:41,312,415...41,326,663
JBrowse link
G HOXA5 homeobox A5 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:17003488) MGI
Ensembl
PMID:17003488 GO_REF:0000107 NCBI chr21:31,224,017...31,227,819
Ensembl chr21:31,224,977...31,227,994
JBrowse link
G SPDEF SAM pointed domain containing ETS transcription factor involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17347682) Ensembl
MGI
PMID:17347682 GO_REF:0000107 NCBI chr17:37,555,797...37,562,522
Ensembl chr17:37,555,820...37,562,036
JBrowse link
lung neuroendocrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCL1 achaete-scute family bHLH transcription factor 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:9126746) MGI
Ensembl
PMID:9126746 GO_REF:0000107 NCBI chr11:98,182,213...98,185,057
Ensembl chr11:98,182,787...98,183,506
JBrowse link
lung secretory cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP1 forkhead box P1 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chr22:31,907,941...32,538,294
Ensembl chr22:31,912,460...32,154,502
JBrowse link
G FOXP4 forkhead box P4 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chr17:30,554,702...30,608,845
Ensembl chr17:30,554,055...30,589,849
JBrowse link
negative regulation of lung goblet cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP1 forkhead box P1 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chr22:31,907,941...32,538,294
Ensembl chr22:31,912,460...32,154,502
JBrowse link
G FOXP4 forkhead box P4 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chr17:30,554,702...30,608,845
Ensembl chr17:30,554,055...30,589,849
JBrowse link
positive regulation of lung ciliated cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXJ1 forkhead box J1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:45,536,973...45,544,331
Ensembl chr16:45,539,510...45,544,299
JBrowse link
G TP73 tumor protein p73 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:127,958,002...128,035,792
Ensembl chr20:127,958,809...128,013,691
JBrowse link
regulation of lung goblet cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP1 forkhead box P1 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chr22:31,907,941...32,538,294
Ensembl chr22:31,912,460...32,154,502
JBrowse link
G FOXP4 forkhead box P4 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chr17:30,554,702...30,608,845
Ensembl chr17:30,554,055...30,589,849
JBrowse link
type I pneumocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CREB1 cAMP responsive element binding protein 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:21408140) MGI
Ensembl
PMID:21408140 GO_REF:0000107 NCBI chr10:93,316,774...93,395,187
Ensembl chr10:93,316,840...93,388,832
JBrowse link
G IGF1 insulin like growth factor 1 acts_upstream_of_or_within ISO (PMID:16691571) MGI PMID:16691571 NCBI chr11:97,624,498...97,708,730
Ensembl chr11:97,631,189...97,707,308
JBrowse link
G KLF2 KLF transcription factor 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22001906) Ensembl
MGI
PMID:22001906 GO_REF:0000107 NCBI chr 6:14,832,013...14,834,744
Ensembl chr 6:14,832,029...14,837,462
JBrowse link
G KRAS KRAS proto-oncogene, GTPase involved_in
acts_upstream_of
IEA
ISO
(PMID:24058167) Ensembl
MGI
PMID:24058167 GO_REF:0000107 NCBI chr11:24,963,396...25,010,747
Ensembl chr11:24,973,619...25,005,191
JBrowse link
G LOC103219433 nuclear factor 1 B-type involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:65,043,819...65,487,832
Ensembl chr12:65,256,407...65,481,485
JBrowse link
G LTA4H leukotriene A4 hydrolase ISO RGD PMID:15805137 RGD:2316585 NCBI chr11:91,371,383...91,413,396
Ensembl chr11:91,371,383...91,406,542
JBrowse link
G NCOR2 nuclear receptor corepressor 2 acts_upstream_of_or_within ISO (PMID:22001906) MGI PMID:22001906 NCBI chr11:119,675,363...119,917,059
Ensembl chr11:119,676,345...119,917,000
JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in
acts_upstream_of
IEA
ISO
(PMID:24058167) Ensembl
MGI
PMID:24058167 GO_REF:0000107 NCBI chr16:49,519,749...49,523,967
Ensembl chr16:49,518,185...49,523,898
JBrowse link
G THRA thyroid hormone receptor alpha acts_upstream_of_or_within ISO (PMID:22001906) MGI PMID:22001906 NCBI chr16:66,087,071...66,118,137 JBrowse link
G THRA thyroid hormone receptor alpha involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:66,085,067...66,118,079 JBrowse link
G THRB thyroid hormone receptor beta involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22001906) Ensembl
MGI
PMID:22001906 GO_REF:0000107 NCBI chr15:68,797,410...69,161,256
Ensembl chr15:68,802,078...68,902,292
JBrowse link
type II pneumocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIMP2 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:12819782) MGI
Ensembl
PMID:12819782 GO_REF:0000107 NCBI chr28:15,210,016...15,224,874
Ensembl chr28:15,209,983...15,226,265
JBrowse link
G FGF10 fibroblast growth factor 10 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15531758) Ensembl
MGI
PMID:15531758 GO_REF:0000107 NCBI chr 4:43,080,387...43,163,355
Ensembl chr 4:43,081,831...43,163,432
JBrowse link
G FNDC3B fibronectin type III domain containing 3B acts_upstream_of_or_within ISO (PMID:21704616) MGI PMID:21704616 NCBI chr15:17,060,117...17,428,340
Ensembl chr15:17,059,959...17,428,339
JBrowse link
G GATA6 GATA binding protein 6 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:17164424) MGI
Ensembl
PMID:17164424 GO_REF:0000107 NCBI chr18:58,312,328...58,345,472
Ensembl chr18:58,311,482...58,343,746
JBrowse link
G IGF1 insulin like growth factor 1 acts_upstream_of_or_within ISO (PMID:16691571) MGI PMID:16691571 NCBI chr11:97,624,498...97,708,730
Ensembl chr11:97,631,189...97,707,308
JBrowse link
G LOC103219433 nuclear factor 1 B-type involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:65,043,819...65,487,832
Ensembl chr12:65,256,407...65,481,485
JBrowse link
G NKX2-1 NK2 homeobox 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:17164424) MGI
Ensembl
PMID:17164424 GO_REF:0000107 NCBI chr24:13,274,118...13,317,533
Ensembl chr24:13,310,846...13,317,056
JBrowse link
G RBBP9 RB binding protein 9, serine hydrolase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:32484881) Ensembl
MGI
PMID:32484881 GO_REF:0000107 NCBI chr 2:47,549,090...47,559,459
Ensembl chr 2:47,552,024...47,559,365
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19803
    cellular process 19325
      cellular developmental process 4577
        cell differentiation 4576
          lung cell differentiation 38
            lung basal cell differentiation 0
            lung epithelial cell differentiation + 38
Path 2
Term Annotations click to browse term
  biological_process 19803
    developmental process 6826
      anatomical structure development 6405
        multicellular organism development 5154
          system development 4465
            respiratory system development 317
              lung development 277
                lung cell differentiation 38
                  lung basal cell differentiation 0
                  lung epithelial cell differentiation + 38
paths to the root