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ONTOLOGY REPORT - ANNOTATIONS


Term:lung cell differentiation
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Accession:GO:0060479 term browser browse the term
Definition:The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate.
Synonyms:exact_synonym: pulmonary cell differentiation



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lung cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTNNB1 catenin beta 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:19805295) Ensembl
MGI
PMID:19805295 GO_REF:0000107 NCBI chr23:10,559,722...10,572,933
Ensembl chr23:10,559,718...10,572,927
JBrowse link
club cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GATA6 GATA binding protein 6 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17164424) Ensembl
MGI
PMID:17164424 GO_REF:0000107 NCBI chr 7:65,932,114...65,962,574 JBrowse link
G NFIB nuclear factor I B involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:34,573,136...35,010,319
Ensembl chr11:34,579,431...34,901,322
JBrowse link
G NKX2-1 NK2 homeobox 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17164424) Ensembl
MGI
PMID:17164424 GO_REF:0000107
G RBPJ recombination signal binding protein for immunoglobulin kappa J region involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22797898) Ensembl
MGI
PMID:22797898 GO_REF:0000107 NCBI chr 3:84,060,417...84,286,008
Ensembl chr 3:84,064,440...84,286,360
JBrowse link
lung ciliated cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NFIB nuclear factor I B involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:34,573,136...35,010,319
Ensembl chr11:34,579,431...34,901,322
JBrowse link
lung epithelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL6A1 collagen type VI alpha 1 chain involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:31837950) Ensembl
MGI
PMID:31837950 GO_REF:0000107 NCBI chr31:39,301,718...39,319,895
Ensembl chr31:39,301,748...39,448,062
JBrowse link
G CTNNB1 catenin beta 1 involved_in
acts_upstream_of
IEA
ISO
(PMID:16040629) Ensembl
MGI
PMID:16040629 GO_REF:0000107 NCBI chr23:10,559,722...10,572,933
Ensembl chr23:10,559,718...10,572,927
JBrowse link
G DHCR7 7-dehydrocholesterol reductase acts_upstream_of_or_within ISO (PMID:15005800) MGI PMID:15005800 NCBI chr18:47,257,750...47,277,436
Ensembl chr18:47,261,730...47,274,236
JBrowse link
G FOXA1 forkhead box A1 acts_upstream_of_or_within ISO (PMID:15668254) MGI PMID:15668254 NCBI chr 8:16,072,629...16,083,105
Ensembl chr 8:16,079,140...16,083,807
JBrowse link
G FOXA2 forkhead box A2 acts_upstream_of_or_within ISO (PMID:15668254) MGI PMID:15668254 NCBI chr24:1,010,370...1,013,791
Ensembl chr24:1,010,651...1,013,072
JBrowse link
G GRHL2 grainyhead like transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:3,204,898...3,362,533
Ensembl chr13:3,204,925...3,362,096
JBrowse link
G PPP3R1 protein phosphatase 3 regulatory subunit B, alpha involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16998587) Ensembl
MGI
PMID:16998587 GO_REF:0000107 NCBI chr10:67,242,552...67,308,469
Ensembl chr10:67,244,329...67,275,487
JBrowse link
G PTHLH parathyroid hormone like hormone acts_upstream_of_or_within ISO (PMID:15162506) MGI PMID:15162506 NCBI chr27:19,781,557...19,795,078
Ensembl chr27:19,781,557...19,795,078
JBrowse link
G SAV1 salvador family WW domain containing protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:18369314) Ensembl
MGI
PMID:18369314 GO_REF:0000107 NCBI chr 8:27,034,606...27,061,926
Ensembl chr 8:27,022,628...27,062,611
JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:24191021) Ensembl
MGI
PMID:24191021 GO_REF:0000107 NCBI chr 9:8,275,049...8,278,172
Ensembl chr 9:8,275,049...8,278,172
JBrowse link
G TMEM38B transmembrane protein 38B involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:19515693) Ensembl
MGI
PMID:19515693 GO_REF:0000107 NCBI chr11:61,511,756...61,561,987
Ensembl chr11:61,511,750...61,560,556
JBrowse link
G YAP1 Yes1 associated transcriptional regulator involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:25043473) Ensembl
MGI
PMID:25043473 GO_REF:0000107 NCBI chr 5:29,394,760...29,495,977
Ensembl chr 5:29,394,541...29,496,251
JBrowse link
lung goblet cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGR2 anterior gradient 2, protein disulphide isomerase family member involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22675208) Ensembl
MGI
PMID:22675208 GO_REF:0000107 NCBI chr14:31,303,784...31,316,752
Ensembl chr14:31,305,567...31,316,686
JBrowse link
G HOXA5 homeobox A5 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17003488) Ensembl
MGI
PMID:17003488 GO_REF:0000107 NCBI chr14:40,315,409...40,319,001
Ensembl chr14:40,315,639...40,317,768
JBrowse link
G SPDEF SAM pointed domain containing ETS transcription factor involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17347682) Ensembl
MGI
PMID:17347682 GO_REF:0000107 NCBI chr12:3,814,806...3,831,724
Ensembl chr12:3,815,300...3,831,477
JBrowse link
lung neuroendocrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCL1 achaete-scute family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:9126746) Ensembl
MGI
PMID:9126746 GO_REF:0000107 NCBI chr15:41,694,021...41,696,933
Ensembl chr15:41,694,269...41,695,391
JBrowse link
lung secretory cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP1 forkhead box P1 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chr20:20,438,631...21,020,516
Ensembl chr20:20,788,433...21,016,397
JBrowse link
G FOXP4 forkhead box P4 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chr12:10,239,402...10,292,892
Ensembl chr12:10,258,166...10,291,125
JBrowse link
negative regulation of lung goblet cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP1 forkhead box P1 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chr20:20,438,631...21,020,516
Ensembl chr20:20,788,433...21,016,397
JBrowse link
G FOXP4 forkhead box P4 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chr12:10,239,402...10,292,892
Ensembl chr12:10,258,166...10,291,125
JBrowse link
positive regulation of lung ciliated cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXJ1 forkhead box J1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:4,512,898...4,517,764
Ensembl chr 9:4,513,628...4,517,756
JBrowse link
G TP73 tumor protein p73 involved_in ISO (PMID:34077761) UniProt PMID:34077761 NCBI chr 5:58,194,385...58,241,159
Ensembl chr 5:58,187,826...58,240,839
JBrowse link
regulation of lung goblet cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP1 forkhead box P1 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chr20:20,438,631...21,020,516
Ensembl chr20:20,788,433...21,016,397
JBrowse link
G FOXP4 forkhead box P4 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chr12:10,239,402...10,292,892
Ensembl chr12:10,258,166...10,291,125
JBrowse link
type I pneumocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CREB1 cAMP responsive element binding protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21408140) Ensembl
MGI
PMID:21408140 GO_REF:0000107 NCBI chr37:15,921,214...15,978,492
Ensembl chr37:15,939,138...15,977,556
JBrowse link
G IGF1 insulin like growth factor 1 acts_upstream_of_or_within ISO (PMID:16691571) MGI PMID:16691571 NCBI chr15:41,203,320...41,275,964
Ensembl chr15:41,202,518...41,275,794
JBrowse link
G KLF2 KLF transcription factor 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22001906) Ensembl
MGI
PMID:22001906 GO_REF:0000107 NCBI chr20:46,182,565...46,183,704 JBrowse link
G KRAS KRAS proto-oncogene, GTPase involved_in
acts_upstream_of
IEA
ISO
(PMID:24058167) Ensembl
MGI
PMID:24058167 GO_REF:0000107 NCBI chr27:22,261,753...22,296,704
Ensembl chr27:22,257,941...22,293,369
JBrowse link
G LTA4H leukotriene A4 hydrolase ISO RGD PMID:15805137 RGD:2316585 NCBI chr15:35,795,934...35,830,681
Ensembl chr15:35,795,979...35,830,844
JBrowse link
G NCOR2 nuclear receptor corepressor 2 acts_upstream_of_or_within ISO (PMID:22001906) MGI PMID:22001906 NCBI chr26:5,352,670...5,493,741
Ensembl chr26:5,331,459...5,493,830
JBrowse link
G NFIB nuclear factor I B involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:34,573,136...35,010,319
Ensembl chr11:34,579,431...34,901,322
JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in
acts_upstream_of
IEA
ISO
(PMID:24058167) Ensembl
MGI
PMID:24058167 GO_REF:0000107 NCBI chr 9:8,275,049...8,278,172
Ensembl chr 9:8,275,049...8,278,172
JBrowse link
G THRA thyroid hormone receptor alpha involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22001906) Ensembl
MGI
PMID:22001906 GO_REF:0000107 NCBI chr 9:22,469,466...22,493,445
Ensembl chr 9:22,468,594...22,493,445
JBrowse link
G THRB thyroid hormone receptor beta involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22001906) Ensembl
MGI
PMID:22001906 GO_REF:0000107 NCBI chr23:19,278,650...19,648,547
Ensembl chr23:19,277,493...19,660,283
JBrowse link
type II pneumocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIMP2 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:12819782) Ensembl
MGI
PMID:12819782 GO_REF:0000107 NCBI chr 6:11,438,768...11,446,307
Ensembl chr 6:11,438,803...11,446,308
JBrowse link
G FGF10 fibroblast growth factor 10 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15531758) Ensembl
MGI
PMID:15531758 GO_REF:0000107 NCBI chr 4:65,851,130...65,930,944
Ensembl chr 4:65,851,069...65,928,192
JBrowse link
G FNDC3B fibronectin type III domain containing 3B acts_upstream_of_or_within ISO (PMID:21704616) MGI PMID:21704616 NCBI chr34:36,373,966...36,640,851
Ensembl chr34:36,302,386...36,637,583
JBrowse link
G GATA6 GATA binding protein 6 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17164424) Ensembl
MGI
PMID:17164424 GO_REF:0000107 NCBI chr 7:65,932,114...65,962,574 JBrowse link
G IGF1 insulin like growth factor 1 acts_upstream_of_or_within ISO (PMID:16691571) MGI PMID:16691571 NCBI chr15:41,203,320...41,275,964
Ensembl chr15:41,202,518...41,275,794
JBrowse link
G NFIB nuclear factor I B involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:34,573,136...35,010,319
Ensembl chr11:34,579,431...34,901,322
JBrowse link
G NKX2-1 NK2 homeobox 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17164424) Ensembl
MGI
PMID:17164424 GO_REF:0000107
G RBBP9 RB binding protein 9, serine hydrolase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:32484881) Ensembl
MGI
PMID:32484881 GO_REF:0000107 NCBI chr24:4,704,957...4,712,644
Ensembl chr24:4,704,362...4,710,798
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22100
    cellular process 21630
      cellular developmental process 4648
        cell differentiation 4647
          lung cell differentiation 36
            lung basal cell differentiation 0
            lung epithelial cell differentiation + 36
Path 2
Term Annotations click to browse term
  biological_process 22100
    developmental process 6892
      anatomical structure development 6454
        multicellular organism development 5226
          system development 4549
            respiratory system development 318
              lung development 282
                lung cell differentiation 36
                  lung basal cell differentiation 0
                  lung epithelial cell differentiation + 36
paths to the root