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ONTOLOGY REPORT - ANNOTATIONS


Term:lung cell differentiation
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Accession:GO:0060479 term browser browse the term
Definition:The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate.
Synonyms:exact_synonym: pulmonary cell differentiation



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lung cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTNNB1 catenin beta 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:19805295) Ensembl
MGI
PMID:19805295 GO_REF:0000107 NCBI chr 3:41,104,940...41,145,934
Ensembl chr 3:41,373,726...41,414,030
JBrowse link
club cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GATA6 GATA binding protein 6 acts_upstream_of_or_within ISO (PMID:17164424) MGI PMID:17164424 NCBI chr18:15,411,764...15,444,402 JBrowse link
G NFIB nuclear factor I B involved_in ISO (PMID:21513708) UniProt PMID:21513708 NCBI chr 9:13,923,516...14,376,264 JBrowse link
G NKX2-1 NK2 homeobox 1 acts_upstream_of_or_within ISO (PMID:17164424) MGI PMID:17164424
G RBPJ recombination signal binding protein for immunoglobulin kappa J region acts_upstream_of_or_within ISO (PMID:22797898) MGI PMID:22797898 NCBI chr 4:20,719,548...20,835,439
Ensembl chr 4:25,995,263...26,107,683
JBrowse link
lung ciliated cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NFIB nuclear factor I B involved_in ISO (PMID:21513708) UniProt PMID:21513708 NCBI chr 9:13,923,516...14,376,264 JBrowse link
lung epithelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL6A1 collagen type VI alpha 1 chain involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:31837950) Ensembl
MGI
PMID:31837950 GO_REF:0000107 NCBI chr21:32,322,185...32,346,850
Ensembl chr21:45,584,096...45,607,240
JBrowse link
G CTNNB1 catenin beta 1 involved_in
acts_upstream_of
IEA
ISO
(PMID:16040629) Ensembl
MGI
PMID:16040629 GO_REF:0000107 NCBI chr 3:41,104,940...41,145,934
Ensembl chr 3:41,373,726...41,414,030
JBrowse link
G DHCR7 7-dehydrocholesterol reductase acts_upstream_of_or_within ISO (PMID:15005800) MGI PMID:15005800 NCBI chr11:66,450,230...66,464,214
Ensembl chr11:69,721,741...69,735,715
JBrowse link
G FOXA1 forkhead box A1 acts_upstream_of_or_within ISO (PMID:15668254) MGI PMID:15668254 NCBI chr14:18,347,284...18,352,705 JBrowse link
G FOXA2 forkhead box A2 acts_upstream_of_or_within ISO (PMID:15668254) MGI PMID:15668254 NCBI chr20:22,519,942...22,524,262 JBrowse link
G GRHL2 grainyhead like transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:98,129,147...98,308,120
Ensembl chr 8:100,308,575...100,471,830
JBrowse link
G PPP3R1 protein phosphatase 3 regulatory subunit B, alpha acts_upstream_of_or_within ISO (PMID:16998587) MGI PMID:16998587 NCBI chr2A:68,227,282...68,300,482 JBrowse link
G PTHLH parathyroid hormone like hormone acts_upstream_of_or_within ISO (PMID:15162506) MGI PMID:15162506 NCBI chr12:58,341,361...58,355,804
Ensembl chr12:60,960,071...60,973,750
JBrowse link
G SAV1 salvador family WW domain containing protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:18369314) Ensembl
MGI
PMID:18369314 GO_REF:0000107 NCBI chr14:31,223,140...31,257,871
Ensembl chr14:49,525,687...49,560,347
JBrowse link
G SOX9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO (PMID:24191021) MGI PMID:24191021 NCBI chr17:66,028,737...66,034,122 JBrowse link
G TMEM38B transmembrane protein 38B involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:19515693) Ensembl
MGI
PMID:19515693 GO_REF:0000107 NCBI chr 9:76,854,177...76,938,334
Ensembl chr 9:104,980,935...105,128,988
JBrowse link
G YAP1 Yes1 associated transcriptional regulator involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:25043473) Ensembl
MGI
PMID:25043473 GO_REF:0000107 NCBI chr11:97,061,367...97,186,961
Ensembl chr11:100,552,424...100,681,301
JBrowse link
lung goblet cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGR2 anterior gradient 2, protein disulphide isomerase family member involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22675208) Ensembl
MGI
PMID:22675208 GO_REF:0000107 NCBI chr 7:17,446,275...17,489,802
Ensembl chr 7:16,773,281...16,785,879
JBrowse link
G HOXA5 homeobox A5 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17003488) Ensembl
MGI
PMID:17003488 GO_REF:0000107 NCBI chr 7:27,786,040...27,789,339
Ensembl chr 7:27,385,175...27,388,990
JBrowse link
G SPDEF SAM pointed domain containing ETS transcription factor involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17347682) Ensembl
MGI
PMID:17347682 GO_REF:0000107 Ensembl chr 6:35,202,983...35,209,639 JBrowse link
lung neuroendocrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCL1 achaete-scute family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:9126746) Ensembl
MGI
PMID:9126746 GO_REF:0000107 NCBI chr12:100,536,895...100,539,737
Ensembl chr12:103,932,302...103,932,999
JBrowse link
lung secretory cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP1 forkhead box P1 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chr 3:70,893,933...71,523,892
Ensembl chr 3:72,258,456...72,498,173
JBrowse link
G FOXP4 forkhead box P4 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chr 6:41,133,751...41,189,709
Ensembl chr 6:42,459,420...42,496,205
JBrowse link
negative regulation of lung goblet cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP1 forkhead box P1 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chr 3:70,893,933...71,523,892
Ensembl chr 3:72,258,456...72,498,173
JBrowse link
G FOXP4 forkhead box P4 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chr 6:41,133,751...41,189,709
Ensembl chr 6:42,459,420...42,496,205
JBrowse link
positive regulation of lung ciliated cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXJ1 forkhead box J1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:70,084,920...70,089,865
Ensembl chr17:75,638,634...75,641,666
JBrowse link
G TP73 tumor protein p73 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:2,323,399...2,405,295
Ensembl chr 1:3,476,064...3,529,206
JBrowse link
regulation of lung goblet cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP1 forkhead box P1 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chr 3:70,893,933...71,523,892
Ensembl chr 3:72,258,456...72,498,173
JBrowse link
G FOXP4 forkhead box P4 acts_upstream_of_or_within ISO (PMID:22675208) MGI PMID:22675208 NCBI chr 6:41,133,751...41,189,709
Ensembl chr 6:42,459,420...42,496,205
JBrowse link
type I pneumocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CREB1 cAMP responsive element binding protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21408140) Ensembl
MGI
PMID:21408140 GO_REF:0000107 NCBI chr2B:94,762,796...94,836,304
Ensembl chr2B:212,891,261...212,958,130
JBrowse link
G IGF1 insulin like growth factor 1 acts_upstream_of_or_within ISO (PMID:16691571) MGI PMID:16691571 NCBI chr12:99,986,887...100,066,773
Ensembl chr12:103,385,911...103,462,177
JBrowse link
G KLF2 KLF transcription factor 2 acts_upstream_of_or_within ISO (PMID:22001906) MGI PMID:22001906 NCBI chr19:15,812,506...15,815,244 JBrowse link
G KRAS KRAS proto-oncogene, GTPase involved_in
acts_upstream_of
IEA
ISO
(PMID:24058167) Ensembl
MGI
PMID:24058167 GO_REF:0000107 NCBI chr12:61,062,689...61,108,524
Ensembl chr12:63,679,293...63,724,335
JBrowse link
G LTA4H leukotriene A4 hydrolase ISO RGD PMID:15805137 RGD:2316585 NCBI chr12:93,589,758...93,624,529
Ensembl chr12:96,978,203...97,012,427
JBrowse link
G NCOR2 nuclear receptor corepressor 2 acts_upstream_of_or_within ISO (PMID:22001906) MGI PMID:22001906 NCBI chr12:121,913,368...122,155,031
Ensembl chr12:126,201,779...126,372,745
JBrowse link
G NFIB nuclear factor I B involved_in ISO (PMID:21513708) UniProt PMID:21513708 NCBI chr 9:13,923,516...14,376,264 JBrowse link
G SOX9 SRY-box transcription factor 9 acts_upstream_of ISO (PMID:24058167) MGI PMID:24058167 NCBI chr17:66,028,737...66,034,122 JBrowse link
G THRA thyroid hormone receptor alpha acts_upstream_of_or_within ISO (PMID:22001906) MGI PMID:22001906 NCBI chr17:17,196,459...17,226,263 JBrowse link
G THRB thyroid hormone receptor beta involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22001906) Ensembl
MGI
PMID:22001906 GO_REF:0000107 NCBI chr 3:24,024,025...24,401,024
Ensembl chr 3:24,346,824...24,564,960
JBrowse link
type II pneumocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIMP2 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:12819782) Ensembl
MGI
PMID:12819782 GO_REF:0000107 NCBI chr 7:7,418,406...7,433,020
Ensembl chr 7:6,203,329...6,221,202
JBrowse link
G FGF10 fibroblast growth factor 10 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15531758) Ensembl
MGI
PMID:15531758 GO_REF:0000107 NCBI chr 5:65,979,443...66,069,314
Ensembl chr 5:71,028,187...71,111,706
JBrowse link
G FNDC3B fibronectin type III domain containing 3B acts_upstream_of_or_within ISO (PMID:21704616) MGI PMID:21704616 NCBI chr 3:169,047,205...169,408,664
Ensembl chr 3:177,301,873...177,590,367
JBrowse link
G GATA6 GATA binding protein 6 acts_upstream_of_or_within ISO (PMID:17164424) MGI PMID:17164424 NCBI chr18:15,411,764...15,444,402 JBrowse link
G IGF1 insulin like growth factor 1 acts_upstream_of_or_within ISO (PMID:16691571) MGI PMID:16691571 NCBI chr12:99,986,887...100,066,773
Ensembl chr12:103,385,911...103,462,177
JBrowse link
G NFIB nuclear factor I B involved_in ISO (PMID:21513708) UniProt PMID:21513708 NCBI chr 9:13,923,516...14,376,264 JBrowse link
G NKX2-1 NK2 homeobox 1 acts_upstream_of_or_within ISO (PMID:17164424) MGI PMID:17164424
G RBBP9 RB binding protein 9, serine hydrolase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:32484881) Ensembl
MGI
PMID:32484881 GO_REF:0000107 NCBI chr20:18,451,015...18,459,231
Ensembl chr20:18,422,652...18,430,170
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19380
    cellular process 18938
      cellular developmental process 4474
        cell differentiation 4473
          lung cell differentiation 36
            lung basal cell differentiation 0
            lung epithelial cell differentiation + 36
Path 2
Term Annotations click to browse term
  biological_process 19380
    developmental process 6649
      anatomical structure development 6235
        multicellular organism development 5009
          system development 4352
            respiratory system development 305
              lung development 270
                lung cell differentiation 36
                  lung basal cell differentiation 0
                  lung epithelial cell differentiation + 36
paths to the root