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ONTOLOGY REPORT - ANNOTATIONS

Term:cortical granule exocytosis
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Accession:GO:0060471 term browser browse the term
Definition:The process of secretion by a cell that results in the release of intracellular molecules contained within a cortical granule by fusion of the vesicle with the plasma membrane of a cell. A cortical granule is a specialized secretory vesicle that is released during egg activation that changes the surface of the egg to prevent polyspermy.
Synonyms:related_synonym: cortical granule release;   cortical reaction

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cortical granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myh9 myosin heavy chain 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936492:4,384,215...4,466,229
Ensembl chrNW_004936492:4,384,215...4,466,262 		JBrowse link
G Nlrp5 NLR family pyrin domain containing 5 involved_in ISO (MGI:6323780|PMID:31118423) UniProt PMID:31118423 MGI:6323780 NCBI chrNW_004936562:1,069,745...1,092,383 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15871
    negative regulation of biological process 5108
      negative regulation of reproductive process 85
        negative regulation of fertilization 7
          prevention of polyspermy 7
            cortical granule exocytosis 2
              positive regulation of cortical granule exocytosis by positive regulation of cytosolic calcium ion concentration 0
Path 2
Term Annotations click to browse term
  biological_process 15871
    localization 5129
      establishment of localization 4439
        transport 4141
          export from cell 1003
            secretion by cell 938
              exocytosis 373
                regulated exocytosis 254
                  calcium-ion regulated exocytosis 79
                    cortical granule exocytosis 2
                      positive regulation of cortical granule exocytosis by positive regulation of cytosolic calcium ion concentration 0
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