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ONTOLOGY REPORT - ANNOTATIONS


Term:cortical granule exocytosis
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Accession:GO:0060471 term browser browse the term
Definition:The process of secretion by a cell that results in the release of intracellular molecules contained within a cortical granule by fusion of the vesicle with the plasma membrane of a cell. A cortical granule is a specialized secretory vesicle that is released during egg activation that changes the surface of the egg to prevent polyspermy.
Synonyms:related_synonym: cortical granule release;   cortical reaction



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cortical granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myh9 myosin, heavy polypeptide 9, non-muscle involved_in IMP (MGI:6323780|PMID:31118423) UniProt PMID:31118423 MGI:6323780 NCBI chr15:77,644,788...77,726,315
Ensembl chr15:77,644,787...77,726,375
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G Nlrp5 NLR family, pyrin domain containing 5 involved_in IMP (MGI:6323780|PMID:31118423) UniProt PMID:31118423 MGI:6323780 NCBI chr 7:23,085,314...23,141,348
Ensembl chr 7:23,085,314...23,141,347
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28558
    negative regulation of biological process 5931
      negative regulation of reproductive process 96
        negative regulation of fertilization 8
          prevention of polyspermy 8
            cortical granule exocytosis 2
              positive regulation of cortical granule exocytosis by positive regulation of cytosolic calcium ion concentration 0
Path 2
Term Annotations click to browse term
  biological_process 28558
    localization 5517
      establishment of localization 4808
        transport 4491
          secretion 1214
            secretion by cell 1019
              exocytosis 410
                regulated exocytosis 276
                  calcium-ion regulated exocytosis 77
                    cortical granule exocytosis 2
                      positive regulation of cortical granule exocytosis by positive regulation of cytosolic calcium ion concentration 0
paths to the root