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ONTOLOGY REPORT - ANNOTATIONS

Term:cortical granule exocytosis
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Accession:GO:0060471 term browser browse the term
Definition:The process of secretion by a cell that results in the release of intracellular molecules contained within a cortical granule by fusion of the vesicle with the plasma membrane of a cell. A cortical granule is a specialized secretory vesicle that is released during egg activation that changes the surface of the egg to prevent polyspermy.
Synonyms:related_synonym: cortical granule release;   cortical reaction

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cortical granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYH9 myosin heavy chain 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:18,985,709...19,093,304
Ensembl chr19:18,986,598...19,052,671 		JBrowse link
G NLRP5 NLR family pyrin domain containing 5 involved_in ISO (PMID:31118423) UniProt PMID:31118423 NCBI chr 6:48,589,792...48,653,181
Ensembl chr 6:48,600,935...48,652,860 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17043
    negative regulation of biological process 5657
      negative regulation of reproductive process 93
        negative regulation of fertilization 8
          prevention of polyspermy 8
            cortical granule exocytosis 2
              positive regulation of cortical granule exocytosis by positive regulation of cytosolic calcium ion concentration 0
Path 2
Term Annotations click to browse term
  biological_process 17043
    localization 5425
      establishment of localization 4707
        transport 4401
          export from cell 1080
            secretion by cell 1008
              exocytosis 386
                regulated exocytosis 270
                  calcium-ion regulated exocytosis 77
                    cortical granule exocytosis 2
                      positive regulation of cortical granule exocytosis by positive regulation of cytosolic calcium ion concentration 0
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