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ONTOLOGY REPORT - ANNOTATIONS

Term:cortical granule exocytosis
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Accession:GO:0060471 term browser browse the term
Definition:The process of secretion by a cell that results in the release of intracellular molecules contained within a cortical granule by fusion of the vesicle with the plasma membrane of a cell. A cortical granule is a specialized secretory vesicle that is released during egg activation that changes the surface of the egg to prevent polyspermy.
Synonyms:related_synonym: cortical granule release;   cortical reaction


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cortical granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYH9 myosin heavy chain 9 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:28,063,626...28,122,953
Ensembl chr10:28,063,624...28,122,953 		JBrowse link
G NLRP5 NLR family pyrin domain containing 5 involved_in ISO (MGI:6323780|PMID:31118423) UniProt PMID:31118423 MGI:6323780 NCBI chr 1:101,813,449...101,842,643
Ensembl chr 1:101,813,449...101,842,633 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17917
    negative regulation of biological process 5778
      negative regulation of reproductive process 91
        negative regulation of fertilization 7
          prevention of polyspermy 7
            cortical granule exocytosis 2
              positive regulation of cortical granule exocytosis by positive regulation of cytosolic calcium ion concentration 0
Path 2
Term Annotations click to browse term
  biological_process 17917
    localization 5609
      establishment of localization 4902
        transport 4575
          export from cell 1086
            secretion by cell 999
              exocytosis 394
                regulated exocytosis 268
                  calcium-ion regulated exocytosis 78
                    cortical granule exocytosis 2
                      positive regulation of cortical granule exocytosis by positive regulation of cytosolic calcium ion concentration 0
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