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ONTOLOGY REPORT - ANNOTATIONS

Term:prevention of polyspermy
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Accession:GO:0060468 term browser browse the term
Definition:The negative regulation of fertilization process that takes place as part of egg activation, ensuring that only a single sperm fertilizes the egg.
Synonyms:exact_synonym: negative regulation of fertilization involved in egg activation;   polyspermy block


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prevention of polyspermy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam24 ADAM metallopeptidase domain 24 acts_upstream_of_or_within IMP (PMID:19670298) MGI PMID:19670298 NCBI chr 8:41,128,118...41,135,238
Ensembl chr 8:41,128,118...41,135,238 		JBrowse link
G Astl astacin like metalloendopeptidase involved_in IDA (MGI:5427546|PMID:22472438) UniProt PMID:22472438 MGI:5427546 NCBI chr 2:127,180,559...127,199,575
Ensembl chr 2:127,180,559...127,199,571 		JBrowse link
G Plat plasminogen activator, tissue involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860 		JBrowse link
G Tpst2 protein-tyrosine sulfotransferase 2 acts_upstream_of_or_within IMP (PMID:21339297) MGI PMID:21339297 NCBI chr 5:112,424,548...112,463,222
Ensembl chr 5:112,424,557...112,463,227 		JBrowse link
G Zp1 zona pellucida glycoprotein 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr19:10,891,660...10,897,965
Ensembl chr19:10,891,651...10,897,996 		JBrowse link
G Zp2 zona pellucida glycoprotein 2 involved_in IDA
IBA		 (MGI:5427546|PMID:22472438) UniProt
GO_Central		 PMID:22472438 GO_REF:0000033 MGI:5427546 NCBI chr 7:119,725,985...119,744,514
Ensembl chr 7:119,725,995...119,744,514 		JBrowse link
cortical granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myh9 myosin, heavy polypeptide 9, non-muscle involved_in IMP (MGI:6323780|PMID:31118423) UniProt PMID:31118423 MGI:6323780 NCBI chr15:77,644,788...77,726,315
Ensembl chr15:77,644,787...77,726,375 		JBrowse link
G Nlrp5 NLR family, pyrin domain containing 5 involved_in IMP (MGI:6323780|PMID:31118423) UniProt PMID:31118423 MGI:6323780 NCBI chr 7:23,085,314...23,141,348
Ensembl chr 7:23,085,314...23,141,347 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28573
    negative regulation of biological process 5939
      negative regulation of reproductive process 96
        negative regulation of fertilization 8
          prevention of polyspermy 8
            cortical granule exocytosis + 2
Path 2
Term Annotations click to browse term
  biological_process 28573
    reproductive process 1994
      sexual reproduction 1288
        fertilization 230
          single fertilization 181
            egg activation 14
              prevention of polyspermy 8
                cortical granule exocytosis + 2
paths to the root