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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of digestive system process
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Accession:GO:0060457 term browser browse the term
Definition:Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.


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negative regulation of defecation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crhr2 corticotropin releasing hormone receptor 2 IMP RGD PMID:21277852 RGD:5491003 NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904 		JBrowse link
G Npsr1 neuropeptide S receptor 1 IMP RGD PMID:21708257 RGD:9831204 NCBI chr 8:22,606,946...22,831,558
Ensembl chr 8:22,606,946...22,831,558 		JBrowse link
negative regulation of gastric acid secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpr39 G protein-coupled receptor 39 acts_upstream_of_or_within ISO MGI:3723512 (PMID:17030183) RGD PMID:17030183 NCBI chr13:37,115,258...37,327,312
Ensembl chr13:37,115,102...37,328,267 		JBrowse link
G Nmu neuromedin U involved_in IDA PMID:12584108 UniProt PMID:12584108 RGD:1642125 NCBI chr14:31,844,564...31,872,196
Ensembl chr14:31,844,728...31,872,192 		JBrowse link
G Ptger3 prostaglandin E receptor 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434 		JBrowse link
G Tff2 trefoil factor 2 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:2179101 (PMID:11805131)		 GO_Central
RGD		 PMID:11805131 GO_REF:0000033 NCBI chr20:9,215,750...9,219,619
Ensembl chr20:9,215,761...9,219,619 		JBrowse link
negative regulation of gastric emptying term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nmu neuromedin U involved_in IDA PMID:12584108 UniProt PMID:12584108 RGD:1642125 NCBI chr14:31,844,564...31,872,196
Ensembl chr14:31,844,728...31,872,192 		JBrowse link
negative regulation of gastrin-induced gastric acid secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:15961884 RGD:10043339 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434 		JBrowse link
G Sct secretin involved_in IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:11123201 GO_REF:0000033, RGD:9590235 NCBI chr 1:196,382,857...196,383,668
Ensembl chr 1:196,382,856...196,383,658 		JBrowse link
negative regulation of intestinal absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 IMP RGD PMID:23333829 RGD:11099975 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Hamp hepcidin antimicrobial peptide involved_in ISO
IEA		 (PMID:12469120)
GO_REF:0000107		 RGD
Ensembl		 PMID:12469120 GO_REF:0000107 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891 		JBrowse link
G Isx intestine-specific homeobox acts_upstream_of_or_within ISO MGI:3703167 (PMID:25701869) RGD PMID:25701869 NCBI chr19:13,217,637...13,239,754
Ensembl chr19:13,218,552...13,239,760 		JBrowse link
negative regulation of intestinal cholesterol absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg5 ATP binding cassette subfamily G member 5 involved_in ISO (PMID:11099417) RGD PMID:11099417 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563 		JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 involved_in ISO (PMID:11099417) RGD PMID:11099417 NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912 		JBrowse link
negative regulation of intestinal phytosterol absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg5 ATP binding cassette subfamily G member 5 involved_in ISO (PMID:11099417) RGD PMID:11099417 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563 		JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 involved_in ISO (PMID:11099417) RGD PMID:11099417 NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912 		JBrowse link
negative regulation of pancreatic juice secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 involved_in ISO (MGI:3822255|PMID:18806227) RGD PMID:18806227 MGI:3822255 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722 		JBrowse link
G Stk39 serine threonine kinase 39 involved_in ISO (MGI:5002793|PMID:21317537) RGD PMID:21317537 MGI:5002793 NCBI chr 3:52,913,583...53,179,060
Ensembl chr 3:52,913,585...53,179,060 		JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:21317537)		 Ensembl
RGD		 PMID:21317537 GO_REF:0000107 NCBI chr 4:153,128,334...153,253,905
Ensembl chr 4:153,128,334...153,253,905 		JBrowse link
G Wnk3 WNK lysine deficient protein kinase 3 involved_in ISO (MGI:5002793|PMID:21317537) RGD PMID:21317537 MGI:5002793 NCBI chr  X:20,156,260...20,299,252
Ensembl chr  X:20,157,041...20,296,821 		JBrowse link
G Wnk4 WNK lysine deficient protein kinase 4 acts_upstream_of_or_within ISO (PMID:21317537) RGD PMID:21317537 NCBI chr10:86,202,552...86,219,655
Ensembl chr10:86,188,812...86,231,829 		JBrowse link
negative regulation of saliva secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neurog1 neurogenin 1 involved_in ISO UniProtKB:Q6ZNK6|UniProtKB:Q8TF63 (PMID:23419067) RGD PMID:23419067 NCBI chr17:8,362,878...8,364,397
Ensembl chr17:8,362,821...8,364,571 		JBrowse link
G Tifab TIFA inhibitor involved_in ISO UniProtKB:Q8TF63|UniProtKB:Q92886 (PMID:23419067) RGD PMID:23419067 NCBI chr17:8,433,406...8,436,541
Ensembl chr17:8,431,635...8,436,592 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20115
    multicellular organismal process 8852
      negative regulation of multicellular organismal process 1334
        negative regulation of digestive system process 19
          negative regulation of defecation + 2
          negative regulation of gastric acid secretion + 5
          negative regulation of gastric emptying 1
          negative regulation of hindgut contraction 0
          negative regulation of intestinal absorption + 5
          negative regulation of pancreatic juice secretion 5
          negative regulation of saliva secretion 2
          negative regulation of small intestinal transit 0
Path 2
Term Annotations click to browse term
  biological_process 20115
    biological regulation 13552
      regulation of biological process 13126
        regulation of multicellular organismal process 3333
          regulation of system process 679
            regulation of digestive system process 52
              negative regulation of digestive system process 19
                negative regulation of defecation + 2
                negative regulation of gastric acid secretion + 5
                negative regulation of gastric emptying 1
                negative regulation of hindgut contraction 0
                negative regulation of intestinal absorption + 5
                negative regulation of pancreatic juice secretion 5
                negative regulation of saliva secretion 2
                negative regulation of small intestinal transit 0
paths to the root