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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of digestive system process
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Accession:GO:0060457 term browser browse the term
Definition:Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.

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negative regulation of gastric acid secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpr39 G protein-coupled receptor 39 acts_upstream_of_or_within ISO MGI:3723512 (MGI:3722947|PMID:17030183) RGD PMID:17030183 MGI:3722947 NCBI chr13:42,008,642...42,220,737
Ensembl chr13:42,008,842...42,009,738 		JBrowse link
G Nmu neuromedin U involved_in IDA PMID:12584108 UniProt PMID:12584108, PMID:12584108 RGD:1642125, RGD:1642125 NCBI chr14:34,353,683...34,381,968
Ensembl chr14:34,354,503...34,381,828 		JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide IDA RGD PMID:11764003 RGD:2304192 NCBI chr 3:123,106,694...123,107,534
Ensembl chr 3:123,106,694...123,107,534 		JBrowse link
G Oxtr oxytocin receptor IMP RGD PMID:11764003 RGD:2304192 NCBI chr 4:144,399,326...144,417,598
Ensembl chr 4:144,403,358...144,416,116 		JBrowse link
G Ptger3 prostaglandin E receptor 3 involved_in IMP
IBA		 PMID:21873635 RGD
GO_Central		 PMID:15961884, PMID:21873635, PMID:21873635 RGD:10043339, RGD:13792537, RGD:13792537 NCBI chr 2:263,895,093...263,979,682
Ensembl chr 2:263,895,241...263,979,698 		JBrowse link
G Tff2 trefoil factor 2 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:2179101 (MGI:2158108|PMID:11805131)
PMID:21873635		 RGD PMID:11805131, PMID:21873635, PMID:21873635 MGI:2158108, RGD:13792537, RGD:13792537 NCBI chr20:9,872,669...9,876,008
Ensembl chr20:9,872,680...9,876,008 		JBrowse link
G Ucn urocortin IDA RGD PMID:21540451 RGD:5490560 NCBI chr 6:26,602,144...26,602,974
Ensembl chr 6:26,602,144...26,602,974 		JBrowse link
negative regulation of gastric emptying term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nmu neuromedin U involved_in IDA PMID:12584108 UniProt PMID:12584108, PMID:12584108 RGD:1642125, RGD:1642125 NCBI chr14:34,353,683...34,381,968
Ensembl chr14:34,354,503...34,381,828 		JBrowse link
G Ptger1 prostaglandin E receptor 1 IMP RGD PMID:10807413 RGD:10043357 NCBI chr19:24,799,422...24,803,373
Ensembl chr19:24,800,072...24,803,373 		JBrowse link
negative regulation of gastrin-induced gastric acid secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:15961884 RGD:10043339 NCBI chr 2:263,895,093...263,979,682
Ensembl chr 2:263,895,241...263,979,698 		JBrowse link
G Sct secretin involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:11123201, PMID:21873635, PMID:21873635 RGD:9590235, RGD:13792537, RGD:13792537 NCBI chr 1:214,264,865...214,277,437
Ensembl chr 1:214,264,754...214,265,668 		JBrowse link
negative regulation of intestinal absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 IMP RGD PMID:23333829 RGD:11099975 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621 		JBrowse link
G Hamp hepcidin antimicrobial peptide involved_in ISO (PMID:12469120) RGD PMID:12469120 NCBI chr 1:89,368,021...89,369,960
Ensembl chr 1:89,368,021...89,369,960 		JBrowse link
G Isx intestine-specific homeobox acts_upstream_of_or_within ISO MGI:3703167 (MGI:5638293|PMID:25701869) RGD PMID:25701869 MGI:5638293 NCBI chr19:14,198,899...14,219,269
Ensembl chr19:14,198,899...14,218,531 		JBrowse link
negative regulation of intestinal cholesterol absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg5 ATP binding cassette subfamily G member 5 involved_in ISO (PMID:11099417) RGD PMID:11099417 NCBI chr 6:7,935,771...7,961,207
Ensembl chr 6:7,935,771...7,961,207 		JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 involved_in ISO (PMID:11099417) RGD PMID:11099417 NCBI chr 6:7,961,413...7,980,708
Ensembl chr 6:7,961,413...7,980,708 		JBrowse link
negative regulation of intestinal phytosterol absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg5 ATP binding cassette subfamily G member 5 involved_in ISO (PMID:11099417) RGD PMID:11099417 NCBI chr 6:7,935,771...7,961,207
Ensembl chr 6:7,935,771...7,961,207 		JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 involved_in ISO (PMID:11099417) RGD PMID:11099417 NCBI chr 6:7,961,413...7,980,708
Ensembl chr 6:7,961,413...7,980,708 		JBrowse link
negative regulation of pancreatic juice secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 involved_in ISO
IEA		 (MGI:3822255|PMID:18806227)
GO_REF:0000107		 RGD
Ensembl		 PMID:18806227 GO_REF:0000107 MGI:3822255 NCBI chr 3:80,004,130...80,014,197
Ensembl chr 3:80,004,130...80,012,750 		JBrowse link
G Stk39 serine threonine kinase 39 involved_in ISO (MGI:5002793|PMID:21317537) RGD PMID:21317537 MGI:5002793 NCBI chr 3:54,359,449...54,625,702
Ensembl chr 3:54,359,451...54,625,414 		JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 acts_upstream_of_or_within ISO (MGI:5002793|PMID:21317537) RGD PMID:21317537 MGI:5002793 NCBI chr 4:152,452,211...152,578,469
Ensembl chr 4:152,452,848...152,578,446 		JBrowse link
G Wnk3 WNK lysine deficient protein kinase 3 involved_in ISO (MGI:5002793|PMID:21317537) RGD PMID:21317537 MGI:5002793 NCBI chr  X:20,316,081...20,459,245
Ensembl chr  X:20,316,893...20,454,357 		JBrowse link
G Wnk4 WNK lysine deficient protein kinase 4 acts_upstream_of_or_within ISO (MGI:5002793|PMID:21317537) RGD PMID:21317537 MGI:5002793 NCBI chr10:89,181,139...89,198,213
Ensembl chr10:89,181,165...89,198,213 		JBrowse link
negative regulation of saliva secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neurog1 neurogenin 1 involved_in ISO UniProtKB:Q6ZNK6|UniProtKB:Q8TF63 (PMID:23419067) RGD PMID:23419067 NCBI chr17:9,154,656...9,156,175
Ensembl chr17:9,154,656...9,156,175 		JBrowse link
G Tifab TIFA inhibitor involved_in ISO UniProtKB:Q8TF63|UniProtKB:Q92886 (PMID:23419067) RGD PMID:23419067 NCBI chr17:9,234,948...9,239,266
Ensembl chr17:9,236,249...9,239,265 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20082
    multicellular organismal process 9081
      negative regulation of multicellular organismal process 1133
        negative regulation of digestive system process 21
          negative regulation of gastric acid secretion + 8
          negative regulation of gastric emptying 2
          negative regulation of hindgut contraction 0
          negative regulation of intestinal absorption + 5
          negative regulation of pancreatic juice secretion 5
          negative regulation of saliva secretion 2
          negative regulation of small intestinal transit 0
Path 2
Term Annotations click to browse term
  biological_process 20082
    biological regulation 13906
      regulation of biological process 13141
        regulation of multicellular organismal process 2932
          regulation of system process 660
            regulation of digestive system process 53
              negative regulation of digestive system process 21
                negative regulation of gastric acid secretion + 8
                negative regulation of gastric emptying 2
                negative regulation of hindgut contraction 0
                negative regulation of intestinal absorption + 5
                negative regulation of pancreatic juice secretion 5
                negative regulation of saliva secretion 2
                negative regulation of small intestinal transit 0
paths to the root