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ONTOLOGY REPORT - ANNOTATIONS


Term:SMAD protein signal transduction
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Accession:GO:0060395 term browser browse the term
Definition:The cascade of processes by which a signal interacts with a receptor, causing a change in the activity of a SMAD protein, and ultimately effecting a change in the functioning of the cell.



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SMAD protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afp alpha-fetoprotein involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:1195384|PMID:9420335)
Ensembl
RGD
PMID:9420335 GO_REF:0000107 MGI:1195384 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
JBrowse link
G Apela apelin receptor early endogenous ligand acts_upstream_of_or_within ISO (MGI:5486383|PMID:23390484) RGD PMID:23390484 MGI:5486383 NCBI chr16:24,694,231...24,703,466 JBrowse link
G Atoh8 atonal bHLH transcription factor 8 involved_in ISO (PMID:24236640) RGD PMID:24236640 NCBI chr 4:104,259,992...104,292,168
Ensembl chr 4:104,259,992...104,292,168
JBrowse link
G Bmp10 bone morphogenetic protein 10 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:119,872,066...119,877,694
Ensembl chr 4:119,872,045...119,878,627
JBrowse link
G Bmp15 bone morphogenetic protein 15 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:16,169,123...16,174,187
Ensembl chr  X:16,169,123...16,174,187
JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:17244894)
UniProt
RGD
PMID:17244894 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G Bmp3 bone morphogenetic protein 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:10,712,489...10,737,153
Ensembl chr14:10,712,489...10,737,153
JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
ISS
GO_REF:0000107
(MGI:1195384|PMID:9420335)
PMID:21873635
(PMID:17244894)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:9420335 PMID:17244894 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:1195384, RGD:13792537 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:76,517,164...76,639,925
Ensembl chr 8:76,517,164...76,639,925
JBrowse link
G Bmp6 bone morphogenetic protein 6 involved_in IBA
ISO
ISS
PMID:21873635
(MGI:4352622|PMID:19252488)
GO_REF:0000024
(PMID:17244894)
RGD
UniProt
PMID:17244894 PMID:19252488 PMID:21873635 GO_REF:0000024 MGI:4352622, RGD:13792537 NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365
JBrowse link
G Bmp7 bone morphogenetic protein 7 involved_in IBA
ISO
PMID:21873635
(PMID:17244894)
RGD PMID:17244894 PMID:21873635 RGD:13792537 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
JBrowse link
G Bmp8a bone morphogenetic protein 8a involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:135,589,839...135,617,785
Ensembl chr 5:135,591,716...135,617,785
JBrowse link
G Bmp8b bone morphogenetic protein 8b involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:135,386,058...135,411,337
Ensembl chr 5:135,386,311...135,405,197
JBrowse link
G Btbd11 BTB domain containing 11 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:5486383|PMID:23390484)
RGD PMID:23390484 PMID:21873635 MGI:5486383, RGD:13792537 NCBI chr 7:18,035,151...18,310,718
Ensembl chr 7:18,036,083...18,310,834
JBrowse link
G Cers1 ceramide synthase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:19,097,309...19,112,519
Ensembl chr16:19,104,466...19,112,519
JBrowse link
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 involved_in ISO (PMID:9707553) RGD PMID:9707553 NCBI chr  X:67,350,376...67,355,072
Ensembl chr  X:67,350,373...67,355,162
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit involved_in ISO (PMID:9732876) RGD PMID:9732876 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Gata4 GATA binding protein 4 acts_upstream_of_or_within ISO (MGI:1195384|PMID:9420335) RGD PMID:9420335 MGI:1195384 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636
JBrowse link
G Gdf1 growth differentiation factor 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:19,097,309...19,112,519
Ensembl chr16:19,097,314...19,112,519
JBrowse link
G Gdf10 growth differentiation factor 10 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:9,237,182...9,250,537
Ensembl chr16:9,237,261...9,249,343
JBrowse link
G Gdf11 growth differentiation factor 11 involved_in ISS
ISO
IBA
GO_REF:0000024
(MGI:3695190|PMID:16845371)
PMID:21873635
(PMID:28257634)
UniProt
RGD
PMID:16845371 PMID:28257634 PMID:21873635 GO_REF:0000024 MGI:3695190, RGD:13792537 NCBI chr 7:1,311,732...1,325,211
Ensembl chr 7:1,311,732...1,320,725
JBrowse link
G Gdf15 growth differentiation factor 15 involved_in ISO
IBA
ISS
IEA
(PMID:25893289)
PMID:21873635
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:25893289 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gdf2 growth differentiation factor 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:9,255,430...9,261,429
Ensembl chr16:9,255,430...9,261,429
JBrowse link
G Gdf3 growth differentiation factor 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:155,831,572...155,835,953
Ensembl chr 4:155,830,909...155,835,937
JBrowse link
G Gdf5 growth differentiation factor 5 involved_in IBA
ISO
PMID:21873635
(PMID:21976273), (PMID:25092592)
RGD PMID:21976273 PMID:25092592 PMID:21873635 RGD:13792537 NCBI chr 3:144,454,306...144,458,757
Ensembl chr 3:144,454,338...144,458,612
JBrowse link
G Gdf6 growth differentiation factor 6 involved_in ISS
ISO
IBA
GO_REF:0000024
(MGI:5751611|PMID:26774823)
PMID:21873635
(PMID:26643732)
UniProt
RGD
PMID:26643732 PMID:26774823 PMID:21873635 GO_REF:0000024 MGI:5751611, RGD:13792537 NCBI chr 5:22,996,246...23,012,567
Ensembl chr 5:22,996,246...23,012,567
JBrowse link
G Gdf7 growth differentiation factor 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:31,171,495...31,182,447
Ensembl chr 6:31,178,119...31,182,447
JBrowse link
G Gdf9 growth differentiation factor 9 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:37,589,200...37,599,970
Ensembl chr10:37,595,679...37,599,672
JBrowse link
G Hexa hexosaminidase subunit alpha acts_upstream_of_or_within ISO (MGI:5486383|PMID:23390484) RGD PMID:23390484 MGI:5486383 NCBI chr 8:59,936,526...59,961,654
Ensembl chr 8:59,936,660...59,962,013
JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 involved_in ISO (PMID:12874272) RGD PMID:12874272 NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223
JBrowse link
G Hnf1a HNF1 homeobox A acts_upstream_of_or_within ISO (MGI:1195384|PMID:9420335) RGD PMID:9420335 MGI:1195384 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:1195384|PMID:9420335)
Ensembl
RGD
PMID:9420335 GO_REF:0000107 MGI:1195384 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
JBrowse link
G Inha inhibin subunit alpha involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:76,994,465...76,997,366
Ensembl chr 9:76,993,589...76,997,248
JBrowse link
G Inhba inhibin subunit beta A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
JBrowse link
G Inhbb inhibin subunit beta B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:30,530,860...30,536,566
Ensembl chr13:30,530,860...30,537,832
JBrowse link
G Inhbc inhibin subunit beta C involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:63,184,141...63,197,630
Ensembl chr 7:63,184,142...63,197,630
JBrowse link
G Inhbe inhibin subunit beta E involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:63,177,558...63,178,983
Ensembl chr 7:63,176,219...63,179,172
JBrowse link
G Itgb6 integrin subunit beta 6 acts_upstream_of_or_within ISO (MGI:6454091|PMID:30467097) RGD PMID:30467097 MGI:6454091 NCBI chr 3:45,046,295...45,170,532
Ensembl chr 3:45,048,044...45,121,671
JBrowse link
G Jade2 jade family PHD finger 2 acts_upstream_of_or_within ISO (MGI:5486383|PMID:23390484) RGD PMID:23390484 MGI:5486383 NCBI chr10:36,076,483...36,124,210
Ensembl chr10:36,078,917...36,116,984
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit involved_in ISO (PMID:9732876) RGD PMID:9732876 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Lefty1 left right determination factor 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:92,649,226...92,659,722
Ensembl chr13:92,656,323...92,659,720
JBrowse link
G Lefty2 Left-right determination factor 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:92,610,185...92,620,918
Ensembl chr13:92,615,360...92,619,880
JBrowse link
G Lnpep leucyl and cystinyl aminopeptidase acts_upstream_of_or_within ISO (MGI:5486383|PMID:23390484) RGD PMID:23390484 MGI:5486383 NCBI chr 1:58,258,642...58,355,532
Ensembl chr 1:58,258,642...58,354,544
JBrowse link
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:1353670|PMID:10681527)
UniProt
RGD
PMID:10681527 GO_REF:0000024 MGI:1353670 NCBI chr 4:14,388,322...15,870,036
Ensembl chr 4:14,386,399...15,870,240
JBrowse link
G Mir130a microRNA 130a acts_upstream_of_or_within ISO (MGI:5486383|PMID:23390484) RGD PMID:23390484 MGI:5486383 NCBI chr 3:69,822,542...69,822,629
Ensembl chr 3:69,822,542...69,822,629
JBrowse link
G Mir181c microRNA 181c acts_upstream_of_or_within ISO (MGI:5486383|PMID:23390484) RGD PMID:23390484 MGI:5486383 NCBI chr19:23,983,523...23,983,628
Ensembl chr19:23,983,523...23,983,628
JBrowse link
G Mir181d microRNA 181d acts_upstream_of_or_within ISO (MGI:5486383|PMID:23390484) RGD PMID:23390484 MGI:5486383 NCBI chr19:23,983,706...23,983,788
Ensembl chr19:23,983,706...23,983,788
JBrowse link
G Mir185 microRNA 185 acts_upstream_of_or_within ISO (MGI:5486383|PMID:23390484) RGD PMID:23390484 MGI:5486383 NCBI chr11:82,664,716...82,664,795
Ensembl chr11:82,664,716...82,664,795
JBrowse link
G Mir25 microRNA 25 acts_upstream_of_or_within ISO (MGI:5486383|PMID:23390484) RGD PMID:23390484 MGI:5486383 NCBI chr12:17,042,932...17,043,015
Ensembl chr12:17,042,932...17,043,015
JBrowse link
G Mir7-1 microRNA 7-1 acts_upstream_of_or_within ISO (MGI:5486383|PMID:23390484) RGD PMID:23390484 MGI:5486383 NCBI chr17:6,273,264...6,273,360
Ensembl chr17:6,273,264...6,273,360
JBrowse link
G Mstn myostatin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:48,453,982...48,458,809
Ensembl chr 9:48,452,533...48,458,933
JBrowse link
G Nceh1 neutral cholesterol ester hydrolase 1 acts_upstream_of_or_within ISO (MGI:5486383|PMID:23390484) RGD PMID:23390484 MGI:5486383 NCBI chr 2:110,074,985...110,135,592
Ensembl chr 2:110,074,957...110,135,588
JBrowse link
G Nodal nodal growth differentiation factor involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:1195384|PMID:9420335)
RGD PMID:9420335 PMID:21873635 MGI:1195384, RGD:13792537 NCBI chr20:29,368,436...29,376,837
Ensembl chr20:29,368,436...29,376,837
JBrowse link
G Nup93 nucleoporin 93 involved_in ISO
ISS
(PMID:26878725)
(MGI:5787706|PMID:26878725)
GO_REF:0000024
RGD
UniProt
PMID:26878725 GO_REF:0000024 MGI:5787706 NCBI chr19:10,684,214...10,788,009
Ensembl chr19:10,682,075...10,788,026
JBrowse link
G Pias2 protein inhibitor of activated STAT, 2 NOT|involved_in ISO (PMID:16777850) RGD PMID:16777850 NCBI chr18:70,608,034...70,714,295
Ensembl chr18:70,607,665...70,710,033
JBrowse link
G Rbm14 RNA binding motif protein 14 acts_upstream_of_or_within ISO (MGI:5486383|PMID:23390484) RGD PMID:23390484 MGI:5486383 NCBI chr 1:202,076,940...202,105,688
Ensembl chr 1:202,078,287...202,105,665
JBrowse link
G Ror2 receptor tyrosine kinase-like orphan receptor 2 acts_upstream_of_or_within ISO MGI:2386954|MGI:3793279 (MGI:4822496|PMID:20660756) RGD PMID:20660756 MGI:4822496 NCBI chr17:11,972,830...12,148,152
Ensembl chr17:11,972,830...12,148,152
JBrowse link
G Ski SKI proto-oncogene involved_in ISO (PMID:12874272) RGD PMID:12874272 NCBI chr 5:165,713,525...165,782,134
Ensembl chr 5:165,714,093...165,782,733
JBrowse link
G Slc33a1 solute carrier family 33 member 1 involved_in ISO (PMID:25402622) RGD PMID:25402622 NCBI chr 2:148,415,660...148,438,182
Ensembl chr 2:148,415,666...148,437,758
JBrowse link
G Smad1 SMAD family member 1 involved_in IEA
ISO
IBA
GO_REF:0000107
UniProtKB:P20722 (MGI:4352622|PMID:19252488)
PMID:21873635
Ensembl
RGD
PMID:19252488 PMID:21873635 GO_REF:0000107 MGI:4352622, RGD:13792537 NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651
JBrowse link
G Smad2 SMAD family member 2 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1201674 (MGI:5486383|PMID:23390484)
RGD PMID:23390484 PMID:21873635 MGI:5486383, RGD:13792537 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
JBrowse link
G Smad3 SMAD family member 3 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:108051 (MGI:5486383|PMID:23390484)
RGD PMID:23390484 PMID:21873635 MGI:5486383, RGD:13792537 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Smad4 SMAD family member 4 involved_in IBA
IEA
ISO
PMID:21873635
GO_REF:0000107
(PMID:9707553), (PMID:9732876)
Ensembl
RGD
PMID:9707553 PMID:9732876 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
G Smad5 SMAD family member 5 involved_in IBA
ISO
PMID:21873635
UniProtKB:P20722 (MGI:4352622|PMID:19252488)
RGD PMID:19252488 PMID:21873635 MGI:4352622, RGD:13792537 NCBI chr17:7,862,332...7,891,678
Ensembl chr17:7,864,720...7,891,634
JBrowse link
G Smad6 SMAD family member 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:64,450,114...64,519,673
Ensembl chr 8:64,450,114...64,519,763
JBrowse link
G Smad7 SMAD family member 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
JBrowse link
G Smad9 SMAD family member 9 involved_in IBA
ISO
PMID:21873635
UniProtKB:P20722 (MGI:4352622|PMID:19252488)
RGD PMID:19252488 PMID:21873635 MGI:4352622, RGD:13792537 NCBI chr 2:138,956,326...139,006,315
Ensembl chr 2:138,986,471...139,006,307
JBrowse link
G Stoml1 stomatin like 1 acts_upstream_of_or_within ISO (MGI:5486383|PMID:23390484) RGD PMID:23390484 MGI:5486383 NCBI chr 8:58,661,980...58,669,860
Ensembl chr 8:58,661,992...58,669,860
JBrowse link
G Sub1 SUB1 regulator of transcription acts_upstream_of_or_within ISO (MGI:5486383|PMID:23390484) RGD PMID:23390484 MGI:5486383 NCBI chr 2:61,005,646...61,020,486
Ensembl chr 2:61,005,666...61,020,436
Ensembl chr 2:61,005,666...61,020,436
JBrowse link
G Tbxt T-box transcription factor T acts_upstream_of_or_within ISO (MGI:1195384|PMID:9420335) RGD PMID:9420335 MGI:1195384 NCBI chr 1:52,298,099...52,309,813
Ensembl chr 1:52,298,099...52,305,864
JBrowse link
G Tf transferrin acts_upstream_of_or_within ISO (MGI:1195384|PMID:9420335) RGD PMID:9420335 MGI:1195384 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:17192487)
AgBase
RGD
PMID:17192487 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Tgfb3 transforming growth factor, beta 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564
JBrowse link
G Vim vimentin involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5486383|PMID:23390484)
Ensembl
RGD
PMID:23390484 GO_REF:0000107 MGI:5486383 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Zmiz1 zinc finger, MIZ-type containing 1 involved_in ISO (PMID:16777850) RGD PMID:16777850 NCBI chr16:1,027,083...1,232,616
Ensembl chr16:1,027,325...1,232,597
JBrowse link
G Zmiz2 zinc finger, MIZ-type containing 2 NOT|involved_in ISO (PMID:16777850) RGD PMID:16777850 NCBI chr14:81,251,391...81,267,936
Ensembl chr14:81,251,417...81,267,936
JBrowse link
negative regulation of SMAD protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccn3 cellular communication network factor 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:5504324|PMID:23653360)
UniProt
RGD
PMID:23653360 GO_REF:0000024 MGI:5504324 NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019
JBrowse link
G Cilp cartilage intermediate layer protein involved_in ISO UniProtKB:P01137 (PMID:29167509) RGD PMID:29167509 NCBI chr 8:65,777,281...65,792,251
Ensembl chr 8:65,777,281...65,792,251
JBrowse link
G Fam89b family with sequence similarity 89, member B involved_in IBA
ISO
PMID:21873635
(MGI:5486566|PMID:12646588)
RGD PMID:12646588 PMID:21873635 MGI:5486566, RGD:13792537 NCBI chr 1:203,015,772...203,017,890
Ensembl chr 1:203,015,773...203,017,367
JBrowse link
G Lrp1 LDL receptor related protein 1 involved_in ISO (MGI:6434720|PMID:31023188) RGD PMID:31023188 MGI:6434720 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910
JBrowse link
G Pbld1 phenazine biosynthesis-like protein domain containing 1 involved_in ISO UniProtKB:Q9Y3F4 (PMID:23687415) RGD PMID:23687415 NCBI chr20:25,551,274...25,566,543
Ensembl chr20:25,551,275...25,565,614
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO UniProtKB:P01137 (PMID:28467929), (PMID:31023188) RGD PMID:28467929 PMID:31023188 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Slc2a10 solute carrier family 2 member 10 acts_upstream_of_or_within ISO (PMID:16550171) RGD PMID:16550171 NCBI chr 3:154,240,395...154,252,690
Ensembl chr 3:154,240,391...154,252,690
JBrowse link
G Ucma upper zone of growth plate and cartilage matrix associated involved_in ISO MGI:5314628 (MGI:6163471|PMID:29563538) RGD PMID:29563538 MGI:6163471 NCBI chr17:73,293,977...73,303,728
Ensembl chr17:73,293,978...73,303,611
JBrowse link
G Veph1 ventricular zone expressed PH domain-containing 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:26039994)
UniProt
Ensembl
RGD
PMID:26039994 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:150,291,379...150,537,491
Ensembl chr 2:150,296,573...150,537,266
JBrowse link
positive regulation of SMAD protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:18382765)
GO_REF:0000107
(MGI:3795340|PMID:18382765)
RGD
Ensembl
PMID:18382765 GO_REF:0000107 MGI:3795340 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:9389648)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:9389648 GO_REF:0000024 GO_REF:0000107 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Bmp6 bone morphogenetic protein 6 involved_in ISO (MGI:4352622|PMID:19252488) RGD PMID:19252488 MGI:4352622 NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365
JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (PMID:9389648) RGD PMID:9389648 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 acts_upstream_of_or_within
involved_in
ISO
IEA
UniProtKB:P12643 (PMID:18382765)
GO_REF:0000107
RGD
Ensembl
PMID:18382765 GO_REF:0000107 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809
JBrowse link
G Dab2 DAB adaptor protein 2 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476
JBrowse link
G Jak2 Janus kinase 2 acts_upstream_of_or_within ISO UniProtKB:Q5VV43 (PMID:28334068) RGD PMID:28334068 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Nodal nodal growth differentiation factor involved_in ISO (PMID:21741376) RGD PMID:21741376 NCBI chr20:29,368,436...29,376,837
Ensembl chr20:29,368,436...29,376,837
JBrowse link
G Nup93 nucleoporin 93 involved_in ISO
ISS
(PMID:26878725)
(MGI:5787706|PMID:26878725)
GO_REF:0000024
RGD
UniProt
PMID:26878725 GO_REF:0000024 MGI:5787706 NCBI chr19:10,684,214...10,788,009
Ensembl chr19:10,682,075...10,788,026
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 involved_in IMP PMID:22073128 BHF-UCL PMID:22073128 RGD:8554355 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pou5f1 POU class 5 homeobox 1 involved_in ISO (PMID:19736317) RGD PMID:19736317 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO UniProtKB:P01137 (PMID:31023188)
UniProtKB:Q91ZX7 (MGI:6434720|PMID:31023188)
RGD PMID:31023188 MGI:6434720 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Rbpms RNA binding protein, mRNA processing factor involved_in ISO (PMID:17099224) RGD PMID:17099224 NCBI chr16:58,239,370...58,395,424
Ensembl chr16:58,239,474...58,395,426
JBrowse link
G RGD1307443 similar to mKIAA0319 protein acts_upstream_of_or_within ISO UniProtKB:O60674|UniProtKB:Q9NRF2 (PMID:28334068) RGD PMID:28334068 NCBI chr17:40,162,512...40,226,666
Ensembl chr17:40,165,084...40,225,653
JBrowse link
G Sh2b1 SH2B adaptor protein 1 acts_upstream_of_or_within ISO UniProtKB:Q5VV43 (PMID:28334068) RGD PMID:28334068 NCBI chr 1:181,048,622...181,057,036
Ensembl chr 1:181,048,623...181,056,579
JBrowse link
G Smad4 SMAD family member 4 involved_in IEA
ISO
GO_REF:0000107
(MGI:2683382|PMID:14691138)
Ensembl
RGD
PMID:14691138 GO_REF:0000107 MGI:2683382 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:19366691), (PMID:28467929), (PMID:29167509), (PMID:31023188), (PMID:9389648)
AgBase
RGD
PMID:9389648 PMID:19366691 PMID:28467929 PMID:29167509 PMID:31023188 GO_REF:0000024 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfb3 transforming growth factor, beta 3 involved_in ISO (MGI:2683382|PMID:14691138) RGD PMID:14691138 MGI:2683382 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISO
IEA
(PMID:9389648)
GO_REF:0000107
RGD
Ensembl
PMID:9389648 GO_REF:0000107 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
regulation of SMAD protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gdf5 growth differentiation factor 5 involved_in ISO (PMID:21976273) RGD PMID:21976273 NCBI chr 3:144,454,306...144,458,757
Ensembl chr 3:144,454,338...144,458,612
JBrowse link
G Ovol2 ovo-like zinc finger 2 involved_in ISO (MGI:6284898|PMID:28455959) RGD PMID:28455959 MGI:6284898 NCBI chr 3:131,677,388...131,707,844
Ensembl chr 3:131,677,391...131,708,359
JBrowse link
G Sptbn1 spectrin, beta, non-erythrocytic 1 acts_upstream_of_or_within ISO (MGI:2449899|PMID:12543979) RGD PMID:12543979 MGI:2449899 NCBI chr14:103,842,684...104,008,507
Ensembl chr14:103,842,684...104,008,507
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:25893292)
UniProt
RGD
PMID:25893292 GO_REF:0000024 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tob1 transducer of ErbB-2.1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:1928565|PMID:11163184)
Ensembl
RGD
PMID:11163184 GO_REF:0000107 MGI:1928565 NCBI chr10:79,163,093...79,165,131
Ensembl chr10:79,160,154...79,165,215
JBrowse link
G Wwtr1 WW domain containing transcription regulator 1 involved_in ISO (PMID:18568018) RGD PMID:18568018 NCBI chr 2:141,651,159...141,766,919
Ensembl chr 2:141,648,108...141,766,968
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    signaling 7490
      signal transduction 6908
        SMAD protein signal transduction 100
          negative regulation of SMAD protein signal transduction 9
          positive regulation of SMAD protein signal transduction 19
          regulation of SMAD protein signal transduction + 32
Path 2
Term Annotations click to browse term
  biological_process 19497
    biological regulation 13606
      regulation of biological process 12866
        regulation of cellular process 12336
          signal transduction 6908
            cell surface receptor signaling pathway 2801
              enzyme linked receptor protein signaling pathway 985
                transmembrane receptor protein serine/threonine kinase signaling pathway 395
                  SMAD protein signal transduction 100
                    negative regulation of SMAD protein signal transduction 9
                    positive regulation of SMAD protein signal transduction 19
                    regulation of SMAD protein signal transduction + 32
paths to the root