Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:mast cell differentiation
go back to main search page
Accession:GO:0060374 term browser browse the term
Definition:The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.



show annotations for term's descendants           Sort by:
 
mast cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata3 GATA binding protein 3 acts_upstream_of_or_within ISO (MGI:3718278|PMID:17603486) RGD PMID:17603486 MGI:3718278 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase involved_in ISO (MGI:3040777|PMID:15067126), (MGI:3604820|PMID:16127161) RGD PMID:15067126 PMID:16127161 MGI:3040777 MGI:3604820 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
negative regulation of mast cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zfpm1 zinc finger protein, multitype 1 involved_in ISO (MGI:3773481|PMID:18063754) RGD PMID:18063754 MGI:3773481 NCBI chr19:50,334,352...50,391,029
Ensembl chr19:50,334,682...50,390,591
JBrowse link
positive regulation of mast cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itgam integrin subunit alpha M involved_in ISO (MGI:1328479|PMID:9862668) RGD PMID:9862668 MGI:1328479 NCBI chr 1:182,659,047...182,709,495
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Pla2g3 phospholipase A2, group III involved_in ISO (MGI:5492190|PMID:23624557) RGD PMID:23624557 MGI:5492190 NCBI chr14:78,367,625...78,373,913
Ensembl chr14:78,368,105...78,373,913
JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO MGI:1857249 (MGI:3605581|PMID:15947484) RGD PMID:15947484 MGI:3605581 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866
JBrowse link
regulation of mast cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tal1 TAL bHLH transcription factor 1, erythroid differentiation factor acts_upstream_of_or_within ISO MGI:1858004|MGI:2450743 (MGI:3847630|PMID:17644741) RGD PMID:17644741 MGI:3847630 NCBI chr 5:128,586,776...128,600,976
Ensembl chr 5:128,587,701...128,600,976
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19541
    developmental process 6920
      cellular developmental process 4576
        cell differentiation 4481
          leukocyte differentiation 618
            myeloid leukocyte differentiation 239
              mast cell differentiation 7
                negative regulation of mast cell differentiation 1
                positive regulation of mast cell differentiation 3
                regulation of mast cell differentiation + 5
Path 2
Term Annotations click to browse term
  biological_process 19541
    developmental process 6920
      anatomical structure development 6337
        multicellular organism development 5765
          system development 5408
            immune system development 1108
              hematopoietic or lymphoid organ development 1041
                hemopoiesis 989
                  myeloid cell differentiation 444
                    myeloid leukocyte differentiation 239
                      mast cell differentiation 7
                        negative regulation of mast cell differentiation 1
                        positive regulation of mast cell differentiation 3
                        regulation of mast cell differentiation + 5
paths to the root