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ONTOLOGY REPORT - ANNOTATIONS

Term:cartilage development involved in endochondral bone morphogenesis
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Accession:GO:0060351 term browser browse the term
Definition:The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones.


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cartilage development involved in endochondral bone morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta synthase acts_upstream_of_or_within ISO MGI:1857139 (MGI:3656462|PMID:15622513) RGD PMID:15622513 MGI:3656462 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764 		JBrowse link
G Col1a1 collagen type I alpha 1 chain acts_upstream_of_or_within ISO MGI:3769585 (MGI:3769669|PMID:18248096) RGD PMID:18248096 MGI:3769669 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col2a1 collagen type II alpha 1 chain acts_upstream_of_or_within IEP
ISO		 mandibular condylar cartilage
MGI:1857275|MGI:2152978 (MGI:3697977|PMID:11680679), (MGI:84914|PMID:8989518), (MGI:85592|PMID:9022054)		 RGD PMID:8989518 PMID:9022054 PMID:11680679 PMID:12924823 MGI:3697977 MGI:84914 MGI:85592, RGD:8661659 NCBI chr 7:129,098,489...129,127,620
Ensembl chr 7:129,098,786...129,127,546 		JBrowse link
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within ISO (MGI:4946896|PMID:21185280), (MGI:5528913|PMID:23958822) RGD PMID:21185280 PMID:23958822 MGI:4946896 MGI:5528913 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357 		JBrowse link
G Ghr growth hormone receptor IEP RGD PMID:15749813 RGD:2307373 NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735 		JBrowse link
G Hoxa11 homeobox A11 acts_upstream_of_or_within ISO MGI:96203 (MGI:3043491|PMID:14668414) RGD PMID:14668414 MGI:3043491 NCBI chr 4:81,342,527...81,346,189
Ensembl chr 4:81,342,528...81,346,232 		JBrowse link
G Hoxd11 homeobox D11 acts_upstream_of_or_within ISO MGI:96172 (MGI:3043491|PMID:14668414) RGD PMID:14668414 MGI:3043491 NCBI chr 3:59,584,840...59,587,257
Ensembl chr 3:59,585,039...59,586,783 		JBrowse link
G Hspg2 heparan sulfate proteoglycan 2 acts_upstream_of_or_within ISO MGI:1934891 (MGI:1930356|PMID:10545953) RGD PMID:10545953 MGI:1930356 NCBI chr 5:149,677,437...149,778,594
Ensembl chr 5:149,677,476...149,778,594 		JBrowse link
G Shox2 short stature homeobox 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:3628798 (MGI:3621617|PMID:16537395)
GO_REF:0000107		 RGD
Ensembl		 PMID:16537395 GO_REF:0000107 MGI:3621617 NCBI chr 2:151,217,049...151,227,180
Ensembl chr 2:151,217,552...151,227,143 		JBrowse link
G Sik3 SIK family kinase 3 acts_upstream_of_or_within ISO MGI:5317918 (MGI:5316542|PMID:22318228) RGD PMID:22318228 MGI:5316542 NCBI chr 8:46,312,253...46,522,444
Ensembl chr 8:46,311,989...46,522,444 		JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 involved_in ISO (PMID:26249260) RGD PMID:26249260 NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517 		JBrowse link
chondrocyte development involved in endochondral bone morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Serpinh1 serpin family H member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2176070|MGI:5505265 (MGI:5494537|PMID:22492985)		 Ensembl
RGD		 PMID:22492985 GO_REF:0000107 MGI:5494537 NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1856877 (MGI:5293259|PMID:21788370)		 Ensembl
RGD		 PMID:21788370 GO_REF:0000107 MGI:5293259 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749 		JBrowse link
chondrocyte differentiation involved in endochondral bone morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Axin2 axin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3579503 (MGI:4818263|PMID:19623616)		 Ensembl
RGD		 PMID:19623616 GO_REF:0000107 MGI:4818263 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
G Ihh Indian hedgehog signaling molecule acts_upstream_of_or_within ISO (MGI:5698232|PMID:25639508) RGD PMID:25639508 MGI:5698232 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532 		JBrowse link
G Scube2 signal peptide, CUB domain and EGF like domain containing 2 acts_upstream_of_or_within ISO MGI:5698367 (MGI:5698232|PMID:25639508) RGD PMID:25639508 MGI:5698232 NCBI chr 1:163,831,876...163,899,925
Ensembl chr 1:163,832,015...163,899,393 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISO
ISS		 (PMID:20676705)
GO_REF:0000024		 RGD
UniProt		 PMID:20676705 GO_REF:0000024 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Trip11 thyroid hormone receptor interactor 11 acts_upstream_of_or_within ISO MGI:4829605 (MGI:4822550|PMID:20089971) RGD PMID:20089971 MGI:4822550 NCBI chr 6:120,995,242...121,067,693
Ensembl chr 6:120,998,733...121,067,781 		JBrowse link
growth plate cartilage axis specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Stc1 stanniocalcin 1 involved_in ISO (PMID:16377640) RGD PMID:16377640 NCBI chr15:44,299,591...44,311,695
Ensembl chr15:44,299,621...44,310,264 		JBrowse link
growth plate cartilage chondrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col27a1 collagen type XXVII alpha 1 chain acts_upstream_of_or_within ISO MGI:5315593 (MGI:5315238|PMID:22206015) RGD PMID:22206015 MGI:5315238 NCBI chr 5:76,647,302...76,765,987
Ensembl chr 5:76,647,429...76,765,174 		JBrowse link
G Poc1a POC1 centriolar protein A acts_upstream_of_or_within ISO MGI:2135614 (MGI:5700251|PMID:26496357) RGD PMID:26496357 MGI:5700251 NCBI chr 8:106,922,058...106,991,678
Ensembl chr 8:106,922,978...106,991,089 		JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:152,660,259...152,671,682
Ensembl chr 1:152,656,693...152,672,588 		JBrowse link
growth plate cartilage chondrocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa6 annexin A6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:39,101,395...39,156,483
Ensembl chr10:39,097,109...39,156,433 		JBrowse link
G Atf2 activating transcription factor 2 involved_in ISO MGI:1857283 (MGI:3807134|PMID:18638549) RGD PMID:18638549 MGI:3807134 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236 		JBrowse link
G Ift80 intraflagellar transport 80 acts_upstream_of_or_within ISO MGI:3665440|MGI:5818514 (MGI:5817320|PMID:26098911) RGD PMID:26098911 MGI:5817320 NCBI chr 2:153,144,707...153,240,024
Ensembl chr 2:153,145,795...153,240,024 		JBrowse link
G Nppc natriuretic peptide C involved_in ISS
ISO		 GO_REF:0000024
(MGI:2177134|PMID:11259675)		 UniProt
RGD		 PMID:11259675 GO_REF:0000024 MGI:2177134 NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251 		JBrowse link
growth plate cartilage chondrocyte growth term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cst5 cystatin D involved_in ISO MGI:3629665 (MGI:3629269|PMID:16680148) RGD PMID:16680148 MGI:3629269 NCBI chr 3:137,573,194...137,577,754
Ensembl chr 3:137,573,194...137,577,754 		JBrowse link
G Rarg retinoic acid receptor, gamma involved_in ISO (MGI:3848572|PMID:19389355) RGD PMID:19389355 MGI:3848572 NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5317468|PMID:22421045)		 UniProt
RGD		 PMID:22421045 GO_REF:0000024 MGI:5317468 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 acts_upstream_of_or_within ISO MGI:2384513 (MGI:4949016|PMID:21420963) RGD PMID:21420963 MGI:4949016 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
growth plate cartilage chondrocyte morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Matn1 matrilin 1 acts_upstream_of_or_within ISO MGI:2153042|MGI:3663272 (MGI:3655339|PMID:16877353) RGD PMID:16877353 MGI:3655339 NCBI chr 5:143,117,198...143,127,140
Ensembl chr 5:143,117,504...143,127,059 		JBrowse link
growth plate cartilage chondrocyte proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf2 activating transcription factor 2 involved_in ISO MGI:1857283 (MGI:3807134|PMID:18638549) RGD PMID:18638549 MGI:3807134 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236 		JBrowse link
G Cer1 cerberus 1, DAN family BMP antagonist involved_in ISO (MGI:5315688|PMID:19113921) RGD PMID:19113921 MGI:5315688 NCBI chr 5:97,306,427...97,309,783
Ensembl chr 5:97,306,431...97,309,783 		JBrowse link
G Nppc natriuretic peptide C involved_in ISS
ISO		 GO_REF:0000024
(MGI:2177134|PMID:11259675)		 UniProt
RGD		 PMID:11259675 GO_REF:0000024 MGI:2177134 NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251 		JBrowse link
growth plate cartilage development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col2a1 collagen type II alpha 1 chain IEP spheno-occipital synchondrosis RGD PMID:20591638 RGD:8661256 NCBI chr 7:129,098,489...129,127,620
Ensembl chr 7:129,098,786...129,127,546 		JBrowse link
G Col9a1 collagen type IX alpha 1 chain acts_upstream_of_or_within ISO MGI:2152964|MGI:88469|MGI:98737|MGI:98739 (MGI:3795666|PMID:18467703), (MGI:3807836|PMID:18191556) RGD PMID:18191556 PMID:18467703 MGI:3795666 MGI:3807836 NCBI chr 9:26,585,034...26,668,222
Ensembl chr 9:26,585,034...26,668,213 		JBrowse link
G Comp cartilage oligomeric matrix protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2180787|MGI:3758741|MGI:88465|MGI:98737|MGI:98739 (MGI:3723532|PMID:17588960), (MGI:3795666|PMID:18467703), (MGI:3807836|PMID:18191556)		 Ensembl
RGD		 PMID:17588960 PMID:18191556 PMID:18467703 GO_REF:0000107 MGI:3723532 MGI:3795666 MGI:3807836 NCBI chr16:19,047,206...19,055,584
Ensembl chr16:19,047,207...19,055,845 		JBrowse link
G Ift80 intraflagellar transport 80 acts_upstream_of_or_within ISO MGI:3665440|MGI:5818514 (MGI:5817320|PMID:26098911) RGD PMID:26098911 MGI:5817320 NCBI chr 2:153,144,707...153,240,024
Ensembl chr 2:153,145,795...153,240,024 		JBrowse link
G Mmp13 matrix metallopeptidase 13 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:98729 (MGI:4949554|PMID:21444811)		 Ensembl
RGD		 PMID:21444811 GO_REF:0000107 MGI:4949554 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239 		JBrowse link
G Npr2 natriuretic peptide receptor 2 involved_in ISO MGI:3774275|MGI:4358115 (MGI:3770504|PMID:17728275), (MGI:5442436|PMID:23065701) RGD PMID:17728275 PMID:23065701 MGI:3770504 MGI:5442436 NCBI chr 5:57,883,171...57,901,590
Ensembl chr 5:57,883,171...57,901,580 		JBrowse link
G Rara retinoic acid receptor, alpha acts_upstream_of_or_within ISO MGI:97858 (MGI:3848572|PMID:19389355) RGD PMID:19389355 MGI:3848572 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142 		JBrowse link
G Rarb retinoic acid receptor, beta acts_upstream_of_or_within ISO MGI:97858 (MGI:3848572|PMID:19389355) RGD PMID:19389355 MGI:3848572 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288 		JBrowse link
G Rarg retinoic acid receptor, gamma acts_upstream_of_or_within ISO MGI:97856|MGI:97857 (MGI:3848572|PMID:19389355) RGD PMID:19389355 MGI:3848572 NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 acts_upstream_of_or_within ISO MGI:1340026 (MGI:4949016|PMID:21420963) RGD PMID:21420963 MGI:4949016 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
G Thbs1 thrombospondin 1 acts_upstream_of_or_within ISO MGI:2154534|MGI:88465|MGI:88469|MGI:98739 (MGI:3795666|PMID:18467703) RGD PMID:18467703 MGI:3795666 NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Thbs3 thrombospondin 3 acts_upstream_of_or_within ISO MGI:3581964|MGI:88465|MGI:88469|MGI:98737 (MGI:3795666|PMID:18467703) RGD PMID:18467703 MGI:3795666 NCBI chr 2:174,621,788...174,633,594
Ensembl chr 2:174,621,812...174,633,594 		JBrowse link
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO MGI:2180033 (MGI:2178865|PMID:11923874) RGD PMID:11923874 MGI:2178865 NCBI chr 5:134,627,218...134,660,360
Ensembl chr 5:134,627,229...134,660,110 		JBrowse link
negative regulation of growth plate cartilage chondrocyte proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dspp dentin sialophosphoprotein acts_upstream_of_or_within ISO MGI:2653208 (MGI:6187806|PMID:26972716) RGD PMID:26972716 MGI:6187806 NCBI chr14:5,565,562...5,571,669
Ensembl chr14:5,565,629...5,571,672 		JBrowse link
regulation of growth plate cartilage chondrocyte proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carm1 coactivator-associated arginine methyltransferase 1 acts_upstream_of_or_within ISO MGI:2663959 (MGI:4365886|PMID:19725955) RGD PMID:19725955 MGI:4365886 NCBI chr 8:20,097,262...20,141,950
Ensembl chr 8:20,097,254...20,147,689 		JBrowse link
G Por cytochrome p450 oxidoreductase IMP positive regulation RGD PMID:19264869 RGD:2316785 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19738
    developmental process 6867
      anatomical structure development 6387
        animal organ development 3643
          cartilage development 231
            cartilage development involved in endochondral bone morphogenesis 43
              chondrocyte differentiation involved in endochondral bone morphogenesis + 18
              growth plate cartilage development + 27
Path 2
Term Annotations click to browse term
  biological_process 19738
    developmental process 6867
      anatomical structure development 6387
        multicellular organism development 5151
          system development 4434
            skeletal system development 562
              bone development 258
                bone morphogenesis 118
                  endochondral bone morphogenesis 73
                    cartilage development involved in endochondral bone morphogenesis 43
                      chondrocyte differentiation involved in endochondral bone morphogenesis + 18
                      growth plate cartilage development + 27
paths to the root