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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of type I interferon-mediated signaling pathway
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Accession:GO:0060339 term browser browse the term
Definition:Any process that decreases the rate, frequency or extent of a type I interferon-mediated signaling pathway.
Synonyms:exact_synonym: negative regulation of type I interferon-mediated signalling pathway



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negative regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAR adenosine deaminase RNA specific acts_upstream_of_or_within ISO (MGI:3821394|PMID:19060901) MGI PMID:19060901 MGI:3821394 NCBI chr 1:129,937,993...129,983,747 JBrowse link
G CACTIN cactin, spliceosome C complex subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:2,636,129...2,652,332
Ensembl chr19:3,586,983...3,601,990
JBrowse link
G CNOT7 CCR4-NOT transcription complex subunit 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:16,439,014...16,459,636
Ensembl chr 8:13,387,288...13,404,445
JBrowse link
G DCST1 DC-STAMP domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:130,381,851...130,398,975
Ensembl chr 1:133,991,485...134,008,614
JBrowse link
G EIF4E2 eukaryotic translation initiation factor 4E family member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:119,782,057...119,814,992
Ensembl chr2B:238,700,790...238,733,654
JBrowse link
G GIGYF2 GRB10 interacting GYF protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:119,929,004...120,090,367
Ensembl chr2B:238,847,674...239,007,549
JBrowse link
G ISG15 ISG15 ubiquitin like modifier involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 1:927,418...928,491 JBrowse link
G MAVS mitochondrial antiviral signaling protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:3,885,044...3,903,554
Ensembl chr20:3,659,559...3,701,089
JBrowse link
G METTL3 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:2,315,868...2,329,460
Ensembl chr14:20,392,665...20,405,906
JBrowse link
G MMP12 matrix metallopeptidase 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:97,809,644...97,822,063
Ensembl chr11:101,294,475...101,306,762
JBrowse link
G MUL1 mitochondrial E3 ubiquitin protein ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:19,454,792...19,463,527
Ensembl chr 1:20,496,356...20,505,281
JBrowse link
G NLRC5 NLR family CARD domain containing 5 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr16:37,267,541...37,361,369
Ensembl chr16:56,433,204...56,494,027
JBrowse link
G OAS1 2'-5'-oligoadenylate synthetase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:110,511,984...110,525,343
Ensembl chr12:113,896,760...113,921,814
JBrowse link
G OAS3 2'-5'-oligoadenylate synthetase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:110,543,522...110,578,463
Ensembl chr12:113,928,202...113,959,654
Ensembl chr12:113,928,202...113,959,654
JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:1,440,837...1,538,501
Ensembl chr18:16,562,052...16,659,570
JBrowse link
G SAMHD1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:33,224,200...33,282,018
Ensembl chr20:34,341,367...34,398,314
JBrowse link
G SMIM30 small integral membrane protein 30 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:105,082,321...105,084,258
Ensembl chr 7:117,784,030...117,784,209
JBrowse link
G STAT2 signal transducer and activator of transcription 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:32,555,523...32,574,137
Ensembl chr12:32,808,586...32,827,732
JBrowse link
G TREX1 three prime repair exonuclease 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3834787|PMID:18724932) MGI
Ensembl
PMID:18724932 GO_REF:0000107 MGI:3834787 NCBI chr 3:48,387,762...48,389,693
Ensembl chr 3:49,470,222...49,471,331
JBrowse link
G TTLL12 tubulin tyrosine ligase like 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:24,038,128...24,070,135
Ensembl chr22:42,249,660...42,271,318
JBrowse link
G USP18 ubiquitin specific peptidase 18 involved_in ISO (PMID:28165510) UniProt PMID:28165510
G YTHDF2 YTH N6-methyladenosine RNA binding protein F2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:28,007,592...28,041,179
Ensembl chr 1:29,038,831...29,070,533
JBrowse link
G YTHDF3 YTH N6-methyladenosine RNA binding protein F3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:59,701,341...59,742,865
Ensembl chr 8:61,375,832...61,413,911
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16309
    cellular process 15385
      signal transduction 5405
        negative regulation of signal transduction 1353
          negative regulation of cytokine-mediated signaling pathway 79
            negative regulation of type I interferon-mediated signaling pathway 23
Path 2
Term Annotations click to browse term
  biological_process 16309
    response to stimulus 8465
      response to biotic stimulus 1610
        response to external biotic stimulus 1568
          response to other organism 1565
            defense response to other organism 1112
              defense response to symbiont 998
                innate immune response 797
                  response to type I interferon 68
                    cellular response to type I interferon 62
                      type I interferon-mediated signaling pathway 59
                        regulation of type I interferon-mediated signaling pathway 41
                          negative regulation of type I interferon-mediated signaling pathway 23
paths to the root