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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of type I interferon-mediated signaling pathway
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Accession:GO:0060339 term browser browse the term
Definition:Any process that decreases the rate, frequency or extent of a type I interferon-mediated signaling pathway.
Synonyms:exact_synonym: negative regulation of type I interferon-mediated signalling pathway


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negative regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adar adenosine deaminase, RNA-specific involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3828307 (PMID:19060901)		 Ensembl
RGD		 PMID:19060901 GO_REF:0000107 NCBI chr 2:175,138,391...175,178,280
Ensembl chr 2:175,138,403...175,178,282 		JBrowse link
G Cactin cactin, spliceosome C complex subunit involved_in ISO (PMID:20829348) RGD PMID:20829348 NCBI chr 7:8,391,396...8,397,219
Ensembl chr 7:8,391,397...8,396,829 		JBrowse link
G Cnot7 CCR4-NOT transcription complex, subunit 7 involved_in ISO (PMID:23386060) RGD PMID:23386060 NCBI chr16:51,775,416...51,794,581
Ensembl chr16:51,775,412...51,794,576 		JBrowse link
G Dcst1 DC-STAMP domain containing 1 involved_in ISO (PMID:27782195) RGD PMID:27782195 NCBI chr 2:174,765,203...174,784,023
Ensembl chr 2:174,765,350...174,781,806 		JBrowse link
G Eif4e2 eukaryotic translation initiation factor 4E family member 2 involved_in ISO (PMID:35878012) RGD PMID:35878012 NCBI chr 9:87,886,126...87,914,470
Ensembl chr 9:87,878,085...87,914,482 		JBrowse link
G Gigyf2 GRB10 interacting GYF protein 2 involved_in ISO (PMID:35878012) RGD PMID:35878012 NCBI chr 9:88,001,212...88,127,040
Ensembl chr 9:88,001,301...88,125,715 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier involved_in ISO (PMID:28724761) RGD PMID:28724761 NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435 		JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISO (PMID:37656786) RGD PMID:37656786 NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094 		JBrowse link
G Mettl3 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit involved_in ISO (PMID:30559377) RGD PMID:30559377 NCBI chr15:25,002,505...25,014,097
Ensembl chr15:25,003,172...25,014,041 		JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:23633945) RGD PMID:23633945 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mmp12 matrix metallopeptidase 12 involved_in IEA
ISO		 GO_REF:0000107
(PMID:24784232)		 Ensembl
RGD		 PMID:24784232 GO_REF:0000107 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611 		JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO (PMID:23399697) RGD PMID:23399697 NCBI chr 5:150,652,812...150,661,863
Ensembl chr 5:150,652,812...150,661,863 		JBrowse link
G Nlrc5 NLR family, CARD domain containing 5 involved_in ISO
IBA		 (PMID:20434986)
GO_REF:0000033		 RGD
GO_Central		 PMID:20434986 GO_REF:0000033 NCBI chr19:10,477,638...10,581,023
Ensembl chr19:10,477,628...10,562,121 		JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A involved_in ISO (PMID:30078389) RGD PMID:30078389 NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517 		JBrowse link
G Oas3 2'-5'-oligoadenylate synthetase 3 involved_in ISO
IEA		 (PMID:30078389)
GO_REF:0000107		 RGD
Ensembl		 PMID:30078389 GO_REF:0000107 NCBI chr12:35,779,028...35,802,781
Ensembl chr12:35,779,022...35,802,781 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISO
ISS
IEA		 (PMID:11909529)
GO_REF:0000024
GO_REF:0000107
(PMID:11909529), (PMID:12138178)		 RGD
UniProt
Ensembl		 PMID:11909529 PMID:12138178 GO_REF:0000024 GO_REF:0000107 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 involved_in ISO (PMID:29670289)
(PMID:23972988)		 RGD PMID:23972988 PMID:29670289 NCBI chr 3:145,761,549...145,794,420
Ensembl chr 3:145,761,558...145,794,386 		JBrowse link
G Smim30 small integral membrane protein 30 involved_in ISO (PMID:37656786) RGD PMID:37656786 NCBI chr  X:34,443,180...34,443,365 JBrowse link
G Stat2 signal transducer and activator of transcription 2 involved_in ISO (PMID:28165510) RGD PMID:28165510 NCBI chr 7:702,565...718,349
Ensembl chr 7:702,495...718,967 		JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO MGI:3052754 (PMID:18724932) RGD PMID:18724932 NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796 		JBrowse link
G Ttll12 tubulin tyrosine ligase like 12 involved_in ISO (PMID:28011935) RGD PMID:28011935 NCBI chr 7:114,731,890...114,751,237
Ensembl chr 7:114,731,892...114,751,356 		JBrowse link
G Usp18 ubiquitin specific peptidase 18 involved_in ISO (PMID:28165510) RGD PMID:28165510 NCBI chr 4:154,471,634...154,499,154
Ensembl chr 4:154,471,592...154,499,144 		JBrowse link
G Ythdf2 YTH N6-methyladenosine RNA binding protein F2 involved_in ISO (PMID:30559377) RGD PMID:30559377 NCBI chr 5:144,381,426...144,407,126
Ensembl chr 5:144,381,431...144,408,144 		JBrowse link
G Ythdf3 YTH N6-methyladenosine RNA binding protein F3 involved_in ISO (PMID:30591559) RGD PMID:30591559 NCBI chr 2:98,350,304...98,384,608
Ensembl chr 2:98,350,588...98,384,606 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20536
    cellular process 19526
      signal transduction 7250
        negative regulation of signal transduction 1501
          negative regulation of cytokine-mediated signaling pathway 95
            negative regulation of type I interferon-mediated signaling pathway 24
Path 2
Term Annotations click to browse term
  biological_process 20536
    response to stimulus 11005
      response to biotic stimulus 1923
        response to external biotic stimulus 1875
          response to other organism 1871
            defense response to other organism 1325
              defense response to symbiont 1098
                innate immune response 1011
                  response to type I interferon 93
                    cellular response to type I interferon 87
                      type I interferon-mediated signaling pathway 85
                        regulation of type I interferon-mediated signaling pathway 42
                          negative regulation of type I interferon-mediated signaling pathway 24
paths to the root