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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of ryanodine-sensitive calcium-release channel activity
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Accession:GO:0060316 term browser browse the term
Definition:Any process that increases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.


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positive regulation of ryanodine-sensitive calcium-release channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap6 A-kinase anchoring protein 6 ISO PMID:12709444 BHF-UCL PMID:12709444 RGD:8554839 NCBI chrNW_004936494:6,744,923...7,228,670 JBrowse link
G Calm2 calmodulin 2 ISO (PMID:20226167) BHF-UCL PMID:20226167 NCBI chrNW_004936508:5,207,909...5,223,780 JBrowse link
G Calm3 calmodulin 3 ISO (PMID:20226167) BHF-UCL PMID:20226167 NCBI chrNW_004936664:471,446...480,858 JBrowse link
G Gsto1 glutathione S-transferase omega 1 ISO (PMID:11035031) BHF-UCL PMID:11035031 NCBI chrNW_004936600:1,932,152...1,943,342 JBrowse link
G LOC101967074 calmodulin ISO (PMID:20226167) BHF-UCL PMID:20226167 NCBI chrNW_004936488:17,580,425...17,588,480 JBrowse link
G Trdn triadin ISO (PMID:15041652), (PMID:15731460) BHF-UCL PMID:15041652, PMID:15731460 NCBI chrNW_004936802:389,653...637,372 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12001
    cellular process 11174
      positive regulation of cellular process 5032
        positive regulation of calcium ion transport into cytosol 63
          positive regulation of release of sequestered calcium ion into cytosol 41
            positive regulation of ryanodine-sensitive calcium-release channel activity 6
Path 2
Term Annotations click to browse term
  biological_process 12001
    biological regulation 8793
      regulation of biological quality 3394
        homeostatic process 1727
          chemical homeostasis 1063
            ion homeostasis 692
              cellular ion homeostasis 548
                cellular cation homeostasis 536
                  cellular metal ion homeostasis 488
                    cellular calcium ion homeostasis 399
                      regulation of cytosolic calcium ion concentration 307
                        positive regulation of cytosolic calcium ion concentration 270
                          calcium ion transport into cytosol 156
                            calcium ion transmembrane import into cytosol 133
                              release of sequestered calcium ion into cytosol 108
                                regulation of release of sequestered calcium ion into cytosol 80
                                  positive regulation of release of sequestered calcium ion into cytosol 41
                                    positive regulation of ryanodine-sensitive calcium-release channel activity 6
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.