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ONTOLOGY REPORT - ANNOTATIONS

Term:elastin catabolic process
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Accession:GO:0060309 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of elastin. Elastin is a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue.
Synonyms:exact_synonym: elastin breakdown;   elastin catabolism;   elastin degradation


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elastin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cela1 chymotrypsin-like elastase family, member 1 acts_upstream_of_or_within IMP (PMID:24793170) MGI PMID:24793170 NCBI chr15:100,572,303...100,585,801
Ensembl chr15:100,572,302...100,585,802 		JBrowse link
G Ctsl cathepsin L involved_in IMP (MGI:6259330|PMID:12417635) UniProt PMID:12417635 MGI:6259330 NCBI chr13:64,509,704...64,518,586
Ensembl chr13:64,507,151...64,518,704 		JBrowse link
G Mmp12 matrix metallopeptidase 12 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:7,344,397...7,360,461
Ensembl chr 9:7,344,381...7,369,499 		JBrowse link
negative regulation of elastin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cst3 cystatin C involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:148,713,642...148,717,432
Ensembl chr 2:148,713,642...148,717,612 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28573
    metabolic process 10995
      primary metabolic process 9507
        protein metabolic process 4150
          glycoprotein metabolic process 363
            glycoprotein catabolic process 29
              elastin catabolic process 4
                negative regulation of elastin catabolic process 1
                positive regulation of elastin catabolic process 0
                regulation of elastin catabolic process + 1
Path 2
Term Annotations click to browse term
  biological_process 28573
    metabolic process 10995
      organic substance metabolic process 10563
        macromolecule metabolic process 8847
          protein metabolic process 4150
            glycoprotein metabolic process 363
              glycoprotein catabolic process 29
                elastin catabolic process 4
                  negative regulation of elastin catabolic process 1
                  positive regulation of elastin catabolic process 0
                  regulation of elastin catabolic process + 1
paths to the root