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ONTOLOGY REPORT - ANNOTATIONS
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Term:
elastin catabolic process
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Accession:
GO:0060309
browse the term
Definition:
The chemical reactions and pathways resulting in the breakdown of elastin. Elastin is a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue.
Synonyms:
exact_synonym:
elastin breakdown; elastin catabolism; elastin degradation
show annotations for term's descendants Sort by:
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object name
position
reference
evidence
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Rat (4)
Mouse (4)
Human (6)
Chinchilla (3)
Bonobo (4)
Dog (6)
Squirrel (3)
Pig (5)
Green Monkey (4)
Naked Mole-rat (2)
All
Genes (4)
elastin catabolic process
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Cela1
chymotrypsin like elastase 1
acts_upstream_of_or_within
ISO
(MGI:5641427|PMID:24793170)
RGD
PMID:24793170
MGI:5641427
NCBI chr 7:131,773,161...131,786,300
Ensembl chr 7:131,742,002...131,786,285
G
Ctsl
cathepsin L
involved_in
ISS
ISO
GO_REF:0000024
(MGI:6259330|PMID:12417635)
UniProt
RGD
PMID:12417635
GO_REF:0000024
MGI:6259330
NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
G
Mmp12
matrix metallopeptidase 12
involved_in
ISO
IEA
(PMID:29101312)
GO_REF:0000107
RGD
Ensembl
PMID:29101312
GO_REF:0000107
NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
negative regulation of elastin catabolic process
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Cst3
cystatin C
involved_in
ISO
(PMID:10545518)
RGD
PMID:10545518
NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822
Term paths to the root
one shortest
all shortest
one longest
all longest
one shortest and longest
all
Path 1
Term
Annotations
biological_process
20325
metabolic process
11737
primary metabolic process
10282
protein metabolic process
4706
glycoprotein metabolic process
387
glycoprotein catabolic process
29
elastin catabolic process
4
negative regulation of elastin catabolic process
1
positive regulation of elastin catabolic process
0
regulation of elastin catabolic process
+
1
Path 2
Term
Annotations
biological_process
20325
metabolic process
11737
organic substance metabolic process
11231
macromolecule metabolic process
9483
protein metabolic process
4706
glycoprotein metabolic process
387
glycoprotein catabolic process
29
elastin catabolic process
4
negative regulation of elastin catabolic process
1
positive regulation of elastin catabolic process
0
regulation of elastin catabolic process
+
1