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ONTOLOGY REPORT - ANNOTATIONS

Term:mesenchymal to epithelial transition
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Accession:GO:0060231 term browser browse the term
Definition:A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell.
Synonyms:exact_synonym: epithelial cell differentiation from mesenchymal cell;   mesenchymal-epithelial transition

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mesenchymal to epithelial transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dspp dentin sialophosphoprotein acts_upstream_of_or_within ISO (PMID:16937369) MGI PMID:16937369 NCBI chrNW_004955474:2,254,842...2,259,303 JBrowse link
G Fzd7 frizzled class receptor 7 involved_in ISO (PMID:17016432) BHF-UCL PMID:17016432 NCBI chrNW_004955457:12,729,277...12,733,057
Ensembl chrNW_004955457:12,731,279...12,732,979 		JBrowse link
G Gata3 GATA binding protein 3 involved_in ISO (PMID:20189993) UniProt PMID:20189993 NCBI chrNW_004955421:24,448,446...24,477,885
Ensembl chrNW_004955421:24,457,496...24,478,744 		JBrowse link
G Pax2 paired box 2 acts_upstream_of_or_within ISO (PMID:8575306) MGI PMID:8575306 NCBI chrNW_004955485:9,351,913...9,430,607
Ensembl chrNW_004955485:9,350,087...9,430,607 		JBrowse link
G Pelo pelota mRNA surveillance and ribosome rescue factor acts_upstream_of_or_within ISO (PMID:24835669) MGI PMID:24835669 NCBI chrNW_004955446:14,564,366...14,566,178
Ensembl chrNW_004955446:14,564,366...14,566,178 		JBrowse link
G Smo smoothened, frizzled class receptor ISO RGD PMID:22994359 RGD:150521663 NCBI chrNW_004955479:9,963,377...9,991,670
Ensembl chrNW_004955479:9,964,170...9,993,165 		JBrowse link
G Tcf15 transcription factor 15 acts_upstream_of_or_within ISO (PMID:24038871) MGI PMID:24038871 NCBI chrNW_004955597:446,489...452,003
Ensembl chrNW_004955597:446,855...451,949 		JBrowse link
G Wnt4 Wnt family member 4 acts_upstream_of_or_within ISO (PMID:7990960)
(PMID:21295565)		 MGI PMID:7990960 PMID:21295565 NCBI chrNW_004955452:2,319,446...2,344,740
Ensembl chrNW_004955452:2,319,446...2,344,989 		JBrowse link
G Wt1 WT1 transcription factor involved_in ISO (MGI:1330701|PMID:9927198), (MGI:62488|PMID:8395349) UniProt PMID:8395349 PMID:9927198 MGI:1330701 MGI:62488 NCBI chrNW_004955476:10,464,688...10,504,473
Ensembl chrNW_004955476:10,464,616...10,504,473 		JBrowse link
mesenchymal to epithelial transition involved in metanephric renal vesicle formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smo smoothened, frizzled class receptor involved_in ISO (MGI:3611729|PMID:16396903) UniProt PMID:16396903 MGI:3611729 NCBI chrNW_004955479:9,963,377...9,991,670
Ensembl chrNW_004955479:9,964,170...9,993,165 		JBrowse link
mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gdnf glial cell derived neurotrophic factor involved_in ISO PMID:17522159
(MGI:1335967|PMID:10322633)		 UniProt PMID:10322633 PMID:17522159 MGI:1335967 RGD:8656002 NCBI chrNW_004955426:22,386,613...22,412,324
Ensembl chrNW_004955426:22,386,450...22,412,324 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (MGI:3714585|PMID:17522159) UniProt PMID:17522159 MGI:3714585 NCBI chrNW_004955416:1,812,725...1,825,528
Ensembl chrNW_004955416:1,812,676...1,826,271 		JBrowse link
G Pax2 paired box 2 involved_in ISO (MGI:1335967|PMID:10322633) UniProt PMID:10322633 MGI:1335967 NCBI chrNW_004955485:9,351,913...9,430,607
Ensembl chrNW_004955485:9,350,087...9,430,607 		JBrowse link
G Pax8 paired box 8 involved_in ISO (PMID:8861958) UniProt PMID:8861958 NCBI chrNW_004955470:1,016,226...1,072,643
Ensembl chrNW_004955470:1,016,289...1,073,796 		JBrowse link
G Sall1 spalt like transcription factor 1 involved_in
acts_upstream_of		 ISO (PMID:11511981)
(PMID:24550112)
(MGI:2149437|PMID:11688560)		 UniProt
MGI		 PMID:11511981 PMID:11688560 PMID:24550112 MGI:2149437 NCBI chrNW_004955433:9,146,074...9,161,171
Ensembl chrNW_004955433:9,144,748...9,161,171 		JBrowse link
G Six2 SIX homeobox 2 involved_in ISO (MGI:1335967|PMID:10322633) UniProt PMID:10322633 MGI:1335967 NCBI chrNW_004955441:12,029,530...12,033,214
Ensembl chrNW_004955441:12,029,480...12,033,214 		JBrowse link
negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cited1 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 involved_in ISO PMID:15843474 UniProt PMID:15843474 RGD:8554075 NCBI chrNW_004955475:11,722,514...11,725,067 JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of_or_within ISO (PMID:17537789) MGI PMID:17537789 NCBI chrNW_004955420:29,030,716...29,047,447
Ensembl chrNW_004955420:29,030,716...29,047,449 		JBrowse link
G Sall1 spalt like transcription factor 1 acts_upstream_of_or_within ISO (PMID:24550112) MGI PMID:24550112 NCBI chrNW_004955433:9,146,074...9,161,171
Ensembl chrNW_004955433:9,144,748...9,161,171 		JBrowse link
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gdnf glial cell derived neurotrophic factor involved_in ISO (MGI:81286|PMID:8657306) UniProt PMID:8657306 MGI:81286 NCBI chrNW_004955426:22,386,613...22,412,324
Ensembl chrNW_004955426:22,386,450...22,412,324 		JBrowse link
G Lif LIF interleukin 6 family cytokine involved_in ISO (PMID:20624457) BHF-UCL PMID:20624457 NCBI chrNW_004955455:4,489,515...4,505,439
Ensembl chrNW_004955455:4,489,421...4,497,940 		JBrowse link
G Pax2 paired box 2 involved_in ISO (MGI:2445273|PMID:12435636) UniProt PMID:12435636 MGI:2445273 NCBI chrNW_004955485:9,351,913...9,430,607
Ensembl chrNW_004955485:9,350,087...9,430,607 		JBrowse link
G Pax8 paired box 8 involved_in ISO (MGI:2445273|PMID:12435636) UniProt PMID:12435636 MGI:2445273 NCBI chrNW_004955470:1,016,226...1,072,643
Ensembl chrNW_004955470:1,016,289...1,073,796 		JBrowse link
regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt9b Wnt family member 9B acts_upstream_of_or_within ISO (PMID:16054034) MGI PMID:16054034 NCBI chrNW_004955478:10,816,405...10,841,416
Ensembl chrNW_004955478:10,816,405...10,841,416 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12346
    cellular process 11480
      cellular developmental process 3877
        cell differentiation 3876
          epithelial cell differentiation 693
            mesenchymal to epithelial transition 18
              mesenchymal to epithelial transition involved in mesonephros morphogenesis + 0
              mesenchymal to epithelial transition involved in metanephros morphogenesis + 11
              mesenchymal to epithelial transition involved in renal vesicle formation + 1
Path 2
Term Annotations click to browse term
  biological_process 12346
    developmental process 5853
      anatomical structure development 5540
        tissue development 1975
          epithelium development 1234
            epithelial cell differentiation 693
              mesenchymal to epithelial transition 18
                mesenchymal to epithelial transition involved in mesonephros morphogenesis + 0
                mesenchymal to epithelial transition involved in metanephros morphogenesis + 11
                mesenchymal to epithelial transition involved in renal vesicle formation + 1
paths to the root