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ONTOLOGY REPORT - ANNOTATIONS


Term:mesenchymal to epithelial transition
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Accession:GO:0060231 term browser browse the term
Definition:A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell.
Synonyms:exact_synonym: epithelial cell differentiation from mesenchymal cell;   mesenchymal-epithelial transition



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mesenchymal to epithelial transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dspp dentin sialophosphoprotein acts_upstream_of_or_within ISO MGI:2653208 (PMID:16937369) RGD PMID:16937369 NCBI chr14:5,565,562...5,571,669
Ensembl chr14:5,565,629...5,571,672
JBrowse link
G Fzd7 frizzled class receptor 7 involved_in ISO (PMID:17016432) RGD PMID:17016432 NCBI chr 9:60,931,433...60,934,252
Ensembl chr 9:60,930,875...60,935,781
JBrowse link
G Gata3 GATA binding protein 3 involved_in ISO (PMID:20189993) RGD PMID:20189993 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
JBrowse link
G H19 H19 imprinted maternally expressed transcript IEP RGD PMID:10862152 RGD:1581114 NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134
JBrowse link
G Pax2 paired box 2 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:1857673 (PMID:8575306)
UniProt
RGD
PMID:8575306 GO_REF:0000024 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321
JBrowse link
G Pelo pelota mRNA surveillance and ribosome rescue factor acts_upstream_of_or_within ISO MGI:2450933 (PMID:24835669) RGD PMID:24835669 NCBI chr 2:46,797,853...46,799,621
Ensembl chr 2:46,797,853...46,799,746
JBrowse link
G Smo smoothened, frizzled class receptor IMP RGD PMID:22994359 RGD:150521663 NCBI chr 4:58,343,626...58,373,823
Ensembl chr 4:58,343,529...58,373,829
JBrowse link
G Tcf15 transcription factor 15 acts_upstream_of_or_within ISO MGI:1929775 (PMID:24038871) RGD PMID:24038871 NCBI chr 3:140,638,984...140,644,766
Ensembl chr 3:140,638,984...140,644,766
JBrowse link
G Wnt4 Wnt family member 4 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:1857435|MGI:1857453 (PMID:21295565), (PMID:7990960)
GO_REF:0000107
RGD
Ensembl
PMID:7990960 PMID:21295565 GO_REF:0000107 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859
JBrowse link
G Wt1 WT1 transcription factor involved_in ISS
ISO
GO_REF:0000024
(PMID:8395349), (PMID:9927198)
UniProt
RGD
PMID:8395349 PMID:9927198 GO_REF:0000024 NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643
JBrowse link
mesenchymal to epithelial transition involved in metanephric renal vesicle formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smo smoothened, frizzled class receptor involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:16396903)
Ensembl
UniProt
RGD
PMID:16396903 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:58,343,626...58,373,823
Ensembl chr 4:58,343,529...58,373,829
JBrowse link
mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gdnf glial cell derived neurotrophic factor involved_in IEA
ISO
IDA
GO_REF:0000107
(PMID:10322633)
PMID:17522159
Ensembl
RGD
PMID:10322633 PMID:17522159 GO_REF:0000107, RGD:8656002 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:17522159) RGD PMID:17522159 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082
JBrowse link
G Pax2 paired box 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:10322633)
UniProt
RGD
PMID:10322633 GO_REF:0000024 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321
JBrowse link
G Pax8 paired box 8 involved_in ISO (PMID:8861958) RGD PMID:8861958 NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363
JBrowse link
G Sall1 spalt-like transcription factor 1 involved_in
acts_upstream_of
ISO (PMID:11511981)
(PMID:11688560)
MGI:3603818 (PMID:24550112)
RGD PMID:11511981 PMID:11688560 PMID:24550112 NCBI chr19:18,005,782...18,022,705
Ensembl chr19:18,007,503...18,022,705
JBrowse link
G Six2 SIX homeobox 2 involved_in ISO (PMID:10322633) RGD PMID:10322633 NCBI chr 6:8,974,859...8,981,345
Ensembl chr 6:8,967,157...8,981,193
JBrowse link
negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 involved_in IMP PMID:15843474 UniProt PMID:15843474 RGD:8554075 NCBI chr  X:67,350,376...67,355,072
Ensembl chr  X:67,350,373...67,355,162
JBrowse link
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:17537789)
Ensembl
RGD
PMID:17537789 GO_REF:0000107 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Sall1 spalt-like transcription factor 1 acts_upstream_of_or_within ISO MGI:3603818 (PMID:24550112) RGD PMID:24550112 NCBI chr19:18,005,782...18,022,705
Ensembl chr19:18,007,503...18,022,705
JBrowse link
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gdnf glial cell derived neurotrophic factor involved_in IEA
ISO
GO_REF:0000107
(PMID:8657306)
Ensembl
RGD
PMID:8657306 GO_REF:0000107 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Lif LIF, interleukin 6 family cytokine involved_in ISO
IEA
(PMID:20624457)
GO_REF:0000107
RGD
Ensembl
PMID:20624457 GO_REF:0000107 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
JBrowse link
G Pax2 paired box 2 involved_in ISS
ISO
GO_REF:0000024
UniProtKB:Q00288 (PMID:12435636)
UniProt
RGD
PMID:12435636 GO_REF:0000024 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321
JBrowse link
G Pax8 paired box 8 involved_in ISS
ISO
GO_REF:0000024
(PMID:12435636)
UniProt
RGD
PMID:12435636 GO_REF:0000024 NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363
JBrowse link
regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt9b Wnt family member 9B acts_upstream_of_or_within ISO MGI:3526437 (PMID:16054034) RGD PMID:16054034 NCBI chr10:88,635,330...88,657,035
Ensembl chr10:88,635,331...88,657,035
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      cellular developmental process 4782
        cell differentiation 4781
          epithelial cell differentiation 851
            mesenchymal to epithelial transition 19
              mesenchymal to epithelial transition involved in mesonephros morphogenesis + 0
              mesenchymal to epithelial transition involved in metanephros morphogenesis + 11
              mesenchymal to epithelial transition involved in renal vesicle formation + 1
Path 2
Term Annotations click to browse term
  biological_process 20076
    developmental process 7070
      anatomical structure development 6573
        tissue development 2303
          epithelium development 1440
            epithelial cell differentiation 851
              mesenchymal to epithelial transition 19
                mesenchymal to epithelial transition involved in mesonephros morphogenesis + 0
                mesenchymal to epithelial transition involved in metanephros morphogenesis + 11
                mesenchymal to epithelial transition involved in renal vesicle formation + 1
paths to the root