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ONTOLOGY REPORT - ANNOTATIONS


Term:mesenchymal to epithelial transition
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Accession:GO:0060231 term browser browse the term
Definition:A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell.
Synonyms:exact_synonym: epithelial cell differentiation from mesenchymal cell;   mesenchymal-epithelial transition


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mesenchymal to epithelial transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dspp dentin sialophosphoprotein acts_upstream_of_or_within ISO MGI:2653208 (MGI:3686561|PMID:16937369) RGD PMID:16937369 MGI:3686561 NCBI chr14:6,926,972...6,933,079
Ensembl chr14:6,926,976...6,933,070
JBrowse link
G Fzd7 frizzled class receptor 7 involved_in ISO (PMID:17016432) RGD PMID:17016432 NCBI chr 9:66,305,731...66,308,550
Ensembl chr 9:66,305,731...66,308,550
JBrowse link
G Gata3 GATA binding protein 3 involved_in ISO
ISS
(PMID:20189993)
GO_REF:0000024
RGD
UniProt
PMID:20189993 GO_REF:0000024 NCBI chr17:72,419,752...72,452,043
Ensembl chr17:72,429,618...72,450,681
JBrowse link
G H19 H19, imprinted maternally expressed transcript (non-protein coding) IEP RGD PMID:10862152 RGD:1581114 NCBI chr 1:215,744,404...215,747,080 JBrowse link
G Pax2 paired box 2 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:1857673 (MGI:77855|PMID:8575306)
UniProt
RGD
PMID:8575306 GO_REF:0000024 MGI:77855 NCBI chr 1:264,493,579...264,585,073
Ensembl chr 1:264,504,591...264,583,329
JBrowse link
G Pelo pelota mRNA surveillance and ribosome rescue factor acts_upstream_of_or_within ISO MGI:2450933 (MGI:5705244|PMID:24835669) RGD PMID:24835669 MGI:5705244 NCBI chr 2:47,266,758...47,268,526
Ensembl chr 2:47,266,738...47,268,625
JBrowse link
G Tcf15 transcription factor 15 acts_upstream_of_or_within ISO MGI:1929775 (MGI:5522599|PMID:24038871) RGD PMID:24038871 MGI:5522599 NCBI chr 3:147,643,250...147,649,511
Ensembl chr 3:147,643,250...147,649,504
JBrowse link
G Wnt4 Wnt family member 4 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857435|MGI:1857453 (MGI:4949991|PMID:21295565), (MGI:69785|PMID:7990960)
Ensembl
RGD
PMID:7990960 PMID:21295565 GO_REF:0000107 MGI:4949991 MGI:69785 NCBI chr 5:155,649,238...155,668,065
Ensembl chr 5:155,649,217...155,672,579
JBrowse link
G Wt1 WT1 transcription factor involved_in ISS
ISO
GO_REF:0000024
(MGI:1330701|PMID:9927198), (MGI:62488|PMID:8395349)
UniProt
RGD
PMID:8395349 PMID:9927198 GO_REF:0000024 MGI:1330701 MGI:62488 NCBI chr 3:95,133,221...95,180,574
Ensembl chr 3:95,133,713...95,180,564
JBrowse link
mesenchymal to epithelial transition involved in metanephric renal vesicle formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smo smoothened, frizzled class receptor involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:3611729|PMID:16396903)
Ensembl
UniProt
RGD
PMID:16396903 GO_REF:0000024 GO_REF:0000107 MGI:3611729 NCBI chr 4:57,019,941...57,041,779
Ensembl chr 4:57,019,941...57,042,770
JBrowse link
mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:10706139)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:10706139 GO_REF:0000024 GO_REF:0000107 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Gdnf glial cell derived neurotrophic factor involved_in
acts_upstream_of_or_within
IEA
ISO
IDA
GO_REF:0000107
(PMID:10322633)
PMID:17522159
Ensembl
RGD
PMID:10322633, PMID:17522159 GO_REF:0000107, RGD:8656002 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (MGI:3714585|PMID:17522159) RGD PMID:17522159 MGI:3714585 NCBI chr 3:105,203,309...105,214,989
Ensembl chr 3:105,203,309...105,214,989
JBrowse link
G Pax2 paired box 2 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(PMID:10322633)
UniProt
RGD
PMID:10322633 GO_REF:0000024 NCBI chr 1:264,493,579...264,585,073
Ensembl chr 1:264,504,591...264,583,329
JBrowse link
G Pax8 paired box 8 involved_in ISO (PMID:8861958) RGD PMID:8861958 NCBI chr 3:1,527,316...1,586,019
Ensembl chr 3:1,527,279...1,584,946
JBrowse link
G Sall1 spalt-like transcription factor 1 involved_in ISO (PMID:11511981)
(MGI:2149437|PMID:11688560)
RGD PMID:11511981 PMID:11688560 MGI:2149437 NCBI chr19:23,387,737...23,405,025
Ensembl chr19:23,389,375...23,405,039
JBrowse link
G Six2 SIX homeobox 2 acts_upstream_of_or_within ISO (PMID:10322633) RGD PMID:10322633 NCBI chr 6:8,952,572...8,955,893
Ensembl chr 6:8,952,572...8,956,276
JBrowse link
negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 involved_in IMP PMID:15843474 UniProt PMID:15843474 RGD:8554075 NCBI chr  X:72,128,996...72,133,692
Ensembl chr  X:72,128,994...72,133,692
JBrowse link
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3714576|PMID:17537789)
Ensembl
RGD
PMID:17537789 GO_REF:0000107 MGI:3714576 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Sall1 spalt-like transcription factor 1 acts_upstream_of_or_within ISO MGI:3603818 (MGI:5563280|PMID:24550112) RGD PMID:24550112 MGI:5563280 NCBI chr19:23,387,737...23,405,025
Ensembl chr19:23,389,375...23,405,039
JBrowse link
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gdnf glial cell derived neurotrophic factor involved_in IEA
ISO
GO_REF:0000107
(MGI:81286|PMID:8657306)
Ensembl
RGD
PMID:8657306 GO_REF:0000107 MGI:81286 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238
JBrowse link
G Lif LIF, interleukin 6 family cytokine involved_in ISO
IEA
(PMID:20624457)
GO_REF:0000107
RGD
Ensembl
PMID:20624457 GO_REF:0000107 NCBI chr14:84,482,652...84,500,574
Ensembl chr14:84,482,674...84,500,642
JBrowse link
G Pax2 paired box 2 involved_in ISS
ISO
GO_REF:0000024
UniProtKB:Q00288 (MGI:2445273|PMID:12435636)
UniProt
RGD
PMID:12435636 GO_REF:0000024 MGI:2445273 NCBI chr 1:264,493,579...264,585,073
Ensembl chr 1:264,504,591...264,583,329
JBrowse link
G Pax8 paired box 8 involved_in ISS
ISO
GO_REF:0000024
(MGI:2445273|PMID:12435636)
UniProt
RGD
PMID:12435636 GO_REF:0000024 MGI:2445273 NCBI chr 3:1,527,316...1,586,019
Ensembl chr 3:1,527,279...1,584,946
JBrowse link
regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt9b Wnt family member 9B acts_upstream_of_or_within ISO MGI:3526437 (MGI:3588895|PMID:16054034) RGD PMID:16054034 MGI:3588895 NCBI chr10:91,785,892...91,808,061
Ensembl chr10:91,785,893...91,807,937
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19612
    cellular process 18457
      cellular developmental process 4461
        cell differentiation 4365
          epithelial cell differentiation 712
            mesenchymal to epithelial transition 20
              mesenchymal to epithelial transition involved in mesonephros morphogenesis + 0
              mesenchymal to epithelial transition involved in metanephros morphogenesis + 12
              mesenchymal to epithelial transition involved in renal vesicle formation + 1
Path 2
Term Annotations click to browse term
  biological_process 19612
    developmental process 6792
      anatomical structure development 6265
        tissue development 2070
          epithelium development 1273
            epithelial cell differentiation 712
              mesenchymal to epithelial transition 20
                mesenchymal to epithelial transition involved in mesonephros morphogenesis + 0
                mesenchymal to epithelial transition involved in metanephros morphogenesis + 12
                mesenchymal to epithelial transition involved in renal vesicle formation + 1
paths to the root