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ONTOLOGY REPORT - ANNOTATIONS


Term:definitive hemopoiesis
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Accession:GO:0060216 term browser browse the term
Definition:A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem cells that continuously provide erythroid, myeloid and lymphoid lineages throughout adulthood.
Synonyms:exact_synonym: definitive haemopoiesis;   definitive hematopoiesis
 related_synonym: definitive haematopoiesis



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definitive hemopoiesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adar adenosine deaminase, RNA-specific involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3029789 (PMID:14615479)
Ensembl
RGD
PMID:14615479 GO_REF:0000107 NCBI chr 2:175,138,391...175,178,280
Ensembl chr 2:175,138,403...175,178,282
JBrowse link
G Bcr BCR activator of RhoGEF and GTPase acts_upstream_of_or_within ISO MGI:2154396 (PMID:7889565) RGD PMID:7889565 NCBI chr20:13,469,325...13,596,942
Ensembl chr20:13,471,668...13,597,016
JBrowse link
G Cbfb core-binding factor subunit beta acts_upstream_of_or_within ISO MGI:1933624 (PMID:9159135) RGD PMID:9159135 NCBI chr19:33,049,162...33,092,752
Ensembl chr19:33,049,172...33,092,751
JBrowse link
G Gata2 GATA binding protein 2 acts_upstream_of_or_within ISO MGI:1857743 (PMID:8078582), (PMID:9822612) RGD PMID:8078582 PMID:9822612 NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761
JBrowse link
G Hoxa9 homeobox A9 acts_upstream_of_or_within ISO MGI:96184|MGI:96185 (PMID:17761289) RGD PMID:17761289 NCBI chr 4:81,323,235...81,329,344
Ensembl chr 4:81,323,382...81,326,358
JBrowse link
G Hoxb3 homeo box B3 acts_upstream_of_or_within ISO MGI:96180|MGI:96185 (PMID:17761289) RGD PMID:17761289 NCBI chr10:81,258,739...81,314,134
Ensembl chr10:81,299,357...81,313,107
JBrowse link
G Hoxb4 homeo box B4 acts_upstream_of_or_within ISO MGI:96180|MGI:96184 (PMID:17761289) RGD PMID:17761289 NCBI chr10:81,284,552...81,287,134
Ensembl chr10:81,284,552...81,287,128
JBrowse link
G Kmt2a lysine methyltransferase 2A involved_in ISO (PMID:15556871) RGD PMID:15556871 NCBI chr 8:45,116,763...45,193,320
Ensembl chr 8:45,118,814...45,193,181
JBrowse link
G Lyl1 LYL1, basic helix-loop-helix family member involved_in ISS
ISO
GO_REF:0000024
(PMID:16514064)
UniProt
RGD
PMID:16514064 GO_REF:0000024 NCBI chr19:23,452,140...23,455,007
Ensembl chr19:23,452,140...23,455,007
JBrowse link
G Meis1 Meis homeobox 1 acts_upstream_of_or_within ISO MGI:3578637 (PMID:15882575) RGD PMID:15882575 NCBI chr14:93,155,426...93,294,373
Ensembl chr14:93,155,419...93,294,265
JBrowse link
G Mfap5 microfibril associated protein 5 involved_in ISO (PMID:23963447) RGD PMID:23963447 NCBI chr 4:155,727,925...155,750,458
Ensembl chr 4:155,727,925...155,750,458
JBrowse link
G Mpl MPL proto-oncogene, thrombopoietin receptor acts_upstream_of_or_within ISO MGI:2686901 (PMID:20711984) RGD PMID:20711984 NCBI chr 5:131,973,895...131,987,472
Ensembl chr 5:131,973,895...131,986,797
JBrowse link
G Runx1 RUNX family transcription factor 1 acts_upstream_of_or_within ISO MGI:1857580 (PMID:10207104) RGD PMID:10207104 NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542
JBrowse link
G Sp1 Sp1 transcription factor acts_upstream_of_or_within ISO MGI:1277166 (PMID:17584888) RGD PMID:17584888 NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961
JBrowse link
G Sp3 Sp3 transcription factor acts_upstream_of_or_within ISO MGI:98372 (PMID:17584888) RGD PMID:17584888 NCBI chr 3:57,811,855...57,857,150
Ensembl chr 3:57,812,075...57,860,342
JBrowse link
G Tal1 TAL bHLH transcription factor 1, erythroid differentiation factor acts_upstream_of_or_within ISO MGI:1857566|MGI:3808120 (PMID:18550854), (PMID:8861941) RGD PMID:8861941 PMID:18550854 NCBI chr 5:128,586,776...128,600,976
Ensembl chr 5:128,587,701...128,600,976
JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 involved_in ISO (PMID:12773577) RGD PMID:12773577 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341
JBrowse link
G Zfp36l2 zinc finger protein 36, C3H type-like 2 involved_in ISO (PMID:19633199) RGD PMID:19633199 NCBI chr 6:10,490,032...10,494,073
Ensembl chr 6:10,490,032...10,494,064
JBrowse link
definitive erythrocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:30635284)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:30635284 GO_REF:0000024 GO_REF:0000107 NCBI chr10:81,894,393...81,903,581
Ensembl chr10:81,894,393...81,903,590
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 acts_upstream_of_or_within ISO MGI:2677822 (PMID:11030619) RGD PMID:11030619 NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032
JBrowse link
G Smarca4 SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4 acts_upstream_of_or_within ISO MGI:3611933 (PMID:16287714) RGD PMID:16287714 NCBI chr 8:20,167,717...20,258,975
Ensembl chr 8:20,167,717...20,258,975
JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 involved_in ISO (PMID:12773577) RGD PMID:12773577 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341
JBrowse link
G Zfpm1 zinc finger protein, multitype 1 acts_upstream_of_or_within ISO MGI:1857554 (PMID:9553047) RGD PMID:9553047 NCBI chr19:50,334,352...50,391,029
Ensembl chr19:50,334,682...50,390,591
JBrowse link
regulation of definitive erythrocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata1 GATA binding protein 1 involved_in ISO (PMID:12200364), (PMID:15920471) RGD PMID:12200364 PMID:15920471 NCBI chr  X:14,529,706...14,537,530
Ensembl chr  X:14,529,702...14,537,530
JBrowse link
G Rbfox2 RNA binding fox-1 homolog 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:17715393)
Ensembl
RGD
PMID:17715393 GO_REF:0000107 NCBI chr 7:108,810,627...109,054,420
Ensembl chr 7:108,810,628...109,054,691
JBrowse link
G Senp1 SUMO specific peptidase 1 acts_upstream_of_or_within ISO MGI:3818522 (PMID:17981124) RGD PMID:17981124 NCBI chr 7:129,163,173...129,226,766
Ensembl chr 7:129,165,774...129,221,598
JBrowse link
G Zfpm1 zinc finger protein, multitype 1 involved_in ISO (PMID:15920471), (PMID:17207461) RGD PMID:15920471 PMID:17207461 NCBI chr19:50,334,352...50,391,029
Ensembl chr19:50,334,682...50,390,591
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20536
    developmental process 7109
      anatomical structure development 6611
        cell development 3339
          hemopoiesis 1079
            definitive hemopoiesis 25
              definitive erythrocyte differentiation + 8
Path 2
Term Annotations click to browse term
  biological_process 20536
    developmental process 7109
      cellular developmental process 4812
        cell differentiation 4811
          cell development 3339
            hemopoiesis 1079
              definitive hemopoiesis 25
                definitive erythrocyte differentiation + 8
paths to the root