ONTOLOGY REPORT - ANNOTATIONS
Term: definitive hemopoiesis
Accession: GO:0060216
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Definition: A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem cells that continuously provide erythroid, myeloid and lymphoid lineages throughout adulthood.
Synonyms: exact_synonym: definitive haemopoiesis; definitive hematopoiesis
related_synonym: definitive haematopoiesis
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Adar
adenosine deaminase, RNA-specific
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:3029789 (PMID:14615479)
Ensembl RGD
PMID:14615479
GO_REF:0000107
NCBI chr 2:175,138,391...175,178,280
Ensembl chr 2:175,138,403...175,178,282
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Bcr
BCR activator of RhoGEF and GTPase
acts_upstream_of_or_within
ISO
MGI:2154396 (PMID:7889565)
RGD
PMID:7889565
NCBI chr20:13,469,325...13,596,942
Ensembl chr20:13,471,668...13,597,016
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Cbfb
core-binding factor subunit beta
acts_upstream_of_or_within
ISO
MGI:1933624 (PMID:9159135)
RGD
PMID:9159135
NCBI chr19:33,049,162...33,092,752
Ensembl chr19:33,049,172...33,092,751
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Gata2
GATA binding protein 2
acts_upstream_of_or_within
ISO
MGI:1857743 (PMID:8078582), (PMID:9822612)
RGD
PMID:8078582 PMID:9822612
NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761
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Hoxa9
homeobox A9
acts_upstream_of_or_within
ISO
MGI:96184|MGI:96185 (PMID:17761289)
RGD
PMID:17761289
NCBI chr 4:81,323,235...81,329,344
Ensembl chr 4:81,323,382...81,326,358
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Hoxb3
homeo box B3
acts_upstream_of_or_within
ISO
MGI:96180|MGI:96185 (PMID:17761289)
RGD
PMID:17761289
NCBI chr10:81,258,739...81,314,134
Ensembl chr10:81,299,357...81,313,107
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Hoxb4
homeo box B4
acts_upstream_of_or_within
ISO
MGI:96180|MGI:96184 (PMID:17761289)
RGD
PMID:17761289
NCBI chr10:81,284,552...81,287,134
Ensembl chr10:81,284,552...81,287,128
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Kmt2a
lysine methyltransferase 2A
involved_in
ISO
(PMID:15556871)
RGD
PMID:15556871
NCBI chr 8:45,116,763...45,193,320
Ensembl chr 8:45,118,814...45,193,181
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Lyl1
LYL1, basic helix-loop-helix family member
involved_in
ISS ISO
GO_REF:0000024 (PMID:16514064)
UniProt RGD
PMID:16514064
GO_REF:0000024
NCBI chr19:23,452,140...23,455,007
Ensembl chr19:23,452,140...23,455,007
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Meis1
Meis homeobox 1
acts_upstream_of_or_within
ISO
MGI:3578637 (PMID:15882575)
RGD
PMID:15882575
NCBI chr14:93,155,426...93,294,373
Ensembl chr14:93,155,419...93,294,265
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Mfap5
microfibril associated protein 5
involved_in
ISO
(PMID:23963447)
RGD
PMID:23963447
NCBI chr 4:155,727,925...155,750,458
Ensembl chr 4:155,727,925...155,750,458
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Mpl
MPL proto-oncogene, thrombopoietin receptor
acts_upstream_of_or_within
ISO
MGI:2686901 (PMID:20711984)
RGD
PMID:20711984
NCBI chr 5:131,973,895...131,987,472
Ensembl chr 5:131,973,895...131,986,797
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Runx1
RUNX family transcription factor 1
acts_upstream_of_or_within
ISO
MGI:1857580 (PMID:10207104)
RGD
PMID:10207104
NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542
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Sp1
Sp1 transcription factor
acts_upstream_of_or_within
ISO
MGI:1277166 (PMID:17584888)
RGD
PMID:17584888
NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961
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Sp3
Sp3 transcription factor
acts_upstream_of_or_within
ISO
MGI:98372 (PMID:17584888)
RGD
PMID:17584888
NCBI chr 3:57,811,855...57,857,150
Ensembl chr 3:57,812,075...57,860,342
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Tal1
TAL bHLH transcription factor 1, erythroid differentiation factor
acts_upstream_of_or_within
ISO
MGI:1857566|MGI:3808120 (PMID:18550854), (PMID:8861941)
RGD
PMID:8861941 PMID:18550854
NCBI chr 5:128,586,776...128,600,976
Ensembl chr 5:128,587,701...128,600,976
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Tgfbr3
transforming growth factor beta receptor 3
involved_in
ISO
(PMID:12773577)
RGD
PMID:12773577
NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341
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Zfp36l2
zinc finger protein 36, C3H type-like 2
involved_in
ISO
(PMID:19633199)
RGD
PMID:19633199
NCBI chr 6:10,490,032...10,494,073
Ensembl chr 6:10,490,032...10,494,064
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Cdk5rap3
CDK5 regulatory subunit associated protein 3
involved_in
ISS ISO IEA
GO_REF:0000024 (PMID:30635284) GO_REF:0000107
UniProt RGD Ensembl
PMID:30635284
GO_REF:0000024 GO_REF:0000107
NCBI chr10:81,894,393...81,903,581
Ensembl chr10:81,894,393...81,903,590
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Ncor1
nuclear receptor co-repressor 1
acts_upstream_of_or_within
ISO
MGI:2677822 (PMID:11030619)
RGD
PMID:11030619
NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032
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Smarca4
SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4
acts_upstream_of_or_within
ISO
MGI:3611933 (PMID:16287714)
RGD
PMID:16287714
NCBI chr 8:20,167,717...20,258,975
Ensembl chr 8:20,167,717...20,258,975
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Tgfbr3
transforming growth factor beta receptor 3
involved_in
ISO
(PMID:12773577)
RGD
PMID:12773577
NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341
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Zfpm1
zinc finger protein, multitype 1
acts_upstream_of_or_within
ISO
MGI:1857554 (PMID:9553047)
RGD
PMID:9553047
NCBI chr19:50,334,352...50,391,029
Ensembl chr19:50,334,682...50,390,591
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Gata1
GATA binding protein 1
involved_in
ISO
(PMID:12200364), (PMID:15920471)
RGD
PMID:12200364 PMID:15920471
NCBI chr X:14,529,706...14,537,530
Ensembl chr X:14,529,702...14,537,530
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Rbfox2
RNA binding fox-1 homolog 2
involved_in
IEA ISO
GO_REF:0000107 (PMID:17715393)
Ensembl RGD
PMID:17715393
GO_REF:0000107
NCBI chr 7:108,810,627...109,054,420
Ensembl chr 7:108,810,628...109,054,691
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Senp1
SUMO specific peptidase 1
acts_upstream_of_or_within
ISO
MGI:3818522 (PMID:17981124)
RGD
PMID:17981124
NCBI chr 7:129,163,173...129,226,766
Ensembl chr 7:129,165,774...129,221,598
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Zfpm1
zinc finger protein, multitype 1
involved_in
ISO
(PMID:15920471), (PMID:17207461)
RGD
PMID:15920471 PMID:17207461
NCBI chr19:50,334,352...50,391,029
Ensembl chr19:50,334,682...50,390,591
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