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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of syncytium formation by plasma membrane fusion
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Accession:GO:0060142 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.


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negative regulation of macrophage fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Stat1 signal transducer and activator of transcription 1 acts_upstream_of_or_within ISO (MGI:5462143|PMID:22865856) MGI PMID:22865856 MGI:5462143 NCBI chrNW_004955403:8,156,660...8,192,018
Ensembl chrNW_004955403:8,156,660...8,194,762
JBrowse link
negative regulation of myoblast fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cflar CASP8 and FADD like apoptosis regulator involved_in ISO (MGI:5707584|PMID:21364645) BHF-UCL PMID:21364645 MGI:5707584 NCBI chrNW_004955403:415,092...442,214
Ensembl chrNW_004955403:412,632...434,741
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 acts_upstream_of_or_within ISO (MGI:5532227|PMID:23844157) MGI PMID:23844157 MGI:5532227 NCBI chrNW_004955433:748,392...750,890
Ensembl chrNW_004955433:748,284...750,927
JBrowse link
G Tmem182 transmembrane protein 182 involved_in ISO (MGI:6810807|PMID:34427057) UniProt PMID:34427057 MGI:6810807 NCBI chrNW_004955470:8,173,845...8,218,325
Ensembl chrNW_004955470:8,173,829...8,218,494
JBrowse link
negative regulation of syncytium formation by plasma membrane fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfe2 nuclear factor, erythroid 2 acts_upstream_of_or_within ISO (MGI:5049808|PMID:21558372) MGI PMID:21558372 MGI:5049808 NCBI chrNW_004955458:1,541,765...1,552,323 JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor 3 involved_in ISO (PMID:23867755) UniProt PMID:23867755 NCBI chrNW_004955500:6,655,056...6,674,311
Ensembl chrNW_004955500:6,655,056...6,674,311
JBrowse link
positive regulation of macrophage fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam9 ADAM metallopeptidase domain 9 involved_in ISO (PMID:11831872) BHF-UCL PMID:11831872 NCBI chrNW_004955463:14,545,425...14,646,498
Ensembl chrNW_004955463:14,545,589...14,645,419
JBrowse link
G Dcstamp dendrocyte expressed seven transmembrane protein involved_in
acts_upstream_of_or_within
ISO (MGI:5426135|PMID:16937266)
(MGI:3588832|PMID:16061724)
(MGI:5462143|PMID:22865856)
UniProt
MGI
PMID:16061724 PMID:16937266 PMID:22865856 MGI:3588832 MGI:5426135 MGI:5462143 NCBI chrNW_004955417:28,156,046...28,169,481
Ensembl chrNW_004955417:28,155,842...28,168,049
JBrowse link
G Ocstamp osteoclast stimulatory transmembrane protein acts_upstream_of_or_within ISO (MGI:5462143|PMID:22865856) MGI PMID:22865856 MGI:5462143 NCBI chrNW_004955445:10,836,404...10,842,811
Ensembl chrNW_004955445:10,836,545...10,842,410
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6142486|PMID:18957693) UniProt PMID:18957693 MGI:6142486 NCBI chrNW_004955437:7,780,886...7,785,597
Ensembl chrNW_004955437:7,780,679...7,785,697
JBrowse link
G Tyrobp transmembrane immune signaling adaptor TYROBP involved_in ISO (PMID:18957693)
(MGI:6142486|PMID:18957693)
UniProt PMID:18957693 MGI:6142486 NCBI chrNW_004955468:2,673,657...2,677,633
Ensembl chrNW_004955468:2,673,980...2,677,321
JBrowse link
positive regulation of myoblast fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrb1 adhesion G protein-coupled receptor B1 involved_in ISO (MGI:5498642|PMID:23615608) UniProt PMID:23615608 MGI:5498642 NCBI chrNW_004955454:1,250,261...1,313,547
Ensembl chrNW_004955454:1,237,363...1,314,127
JBrowse link
G Capn2 calpain 2 ISO RGD PMID:7657725 RGD:13792659 NCBI chrNW_004955520:1,287,829...1,315,318
Ensembl chrNW_004955520:1,286,356...1,315,328
JBrowse link
G Cd53 CD53 molecule involved_in ISO (MGI:5526919|PMID:22847234) UniProt PMID:22847234 MGI:5526919 NCBI chrNW_004955435:14,388,925...14,410,543
Ensembl chrNW_004955435:14,388,726...14,413,249
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 acts_upstream_of_or_within ISO (MGI:5532227|PMID:23844157) MGI PMID:23844157 MGI:5532227 NCBI chrNW_004955546:1,929,269...1,941,690
Ensembl chrNW_004955546:1,929,269...1,941,690
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 acts_upstream_of_or_within ISO (MGI:5532227|PMID:23844157) MGI PMID:23844157 MGI:5532227 NCBI chrNW_004955433:724,566...731,945
Ensembl chrNW_004955433:724,515...732,192
JBrowse link
G Ehd1 EH domain containing 1 involved_in ISO (MGI:5487527|PMID:21177873) UniProt PMID:21177873 MGI:5487527 NCBI chrNW_004955422:20,302,409...20,324,591
Ensembl chrNW_004955422:20,302,655...20,324,591
JBrowse link
G Ehd2 EH domain containing 2 involved_in ISO (MGI:5487527|PMID:21177873) UniProt PMID:21177873 MGI:5487527 NCBI chrNW_004955574:1,490,877...1,503,651
Ensembl chrNW_004955574:1,490,877...1,503,943
JBrowse link
G Flot1 flotillin 1 involved_in ISO (PMID:24046456)
(MGI:5634880|PMID:24046456)
UniProt PMID:24046456 MGI:5634880 NCBI chrNW_004955583:717,246...729,924
Ensembl chrNW_004955583:713,560...729,924
JBrowse link
G Flt3lg fms related receptor tyrosine kinase 3 ligand acts_upstream_of_or_within ISO (MGI:5532227|PMID:23844157) MGI PMID:23844157 MGI:5532227 NCBI chrNW_004955559:1,364,056...1,371,245
Ensembl chrNW_004955559:1,365,938...1,370,002
JBrowse link
G Gdf15 growth differentiation factor 15 acts_upstream_of_or_within ISO (MGI:5532227|PMID:23844157) MGI PMID:23844157 MGI:5532227 NCBI chrNW_004955524:3,123,513...3,125,642
Ensembl chrNW_004955524:3,123,760...3,125,621
JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (MGI:3621675|PMID:12757709) MGI PMID:12757709 MGI:3621675 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
G Il4r interleukin 4 receptor acts_upstream_of_or_within ISO (MGI:3621675|PMID:12757709) MGI PMID:12757709 MGI:3621675 NCBI chrNW_004955493:5,546,340...5,580,745
Ensembl chrNW_004955493:5,545,944...5,582,422
JBrowse link
G Mapk14 mitogen-activated protein kinase 14 involved_in ISO (MGI:5526919|PMID:22847234) UniProt PMID:22847234 MGI:5526919 NCBI chrNW_004955437:3,836,331...3,884,083
Ensembl chrNW_004955437:3,838,232...3,884,083
JBrowse link
G Myod1 myogenic differentiation 1 involved_in ISO (PMID:10672515) BHF-UCL PMID:10672515 NCBI chrNW_004955414:32,523,959...32,526,575
Ensembl chrNW_004955414:32,523,924...32,526,674
JBrowse link
G Nfatc2 nuclear factor of activated T cells 2 acts_upstream_of_or_within ISO (MGI:3621675|PMID:12757709) MGI PMID:12757709 MGI:3621675 NCBI chrNW_004955445:7,035,876...7,153,199
Ensembl chrNW_004955445:7,035,876...7,153,237
JBrowse link
G Ripor2 RHO family interacting cell polarization regulator 2 involved_in ISO (PMID:17150207) UniProt PMID:17150207 NCBI chrNW_004955483:2,048,236...2,257,078
Ensembl chrNW_004955483:2,048,324...2,256,589
JBrowse link
G Scgb3a1 secretoglobin family 3A member 1 acts_upstream_of_or_within ISO (MGI:5532227|PMID:23844157) MGI PMID:23844157 MGI:5532227 NCBI chrNW_004955408:147,777...149,227
Ensembl chrNW_004955408:147,777...149,227
JBrowse link
G Tnfsf14 TNF superfamily member 14 acts_upstream_of_or_within ISO (MGI:5532227|PMID:23844157) MGI PMID:23844157 MGI:5532227 NCBI chrNW_004955495:2,829,314...2,834,826
Ensembl chrNW_004955495:2,829,402...2,835,335
JBrowse link
positive regulation of syncytium formation by plasma membrane fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk1 calcium/calmodulin dependent protein kinase I involved_in ISO (PMID:23867755) UniProt PMID:23867755 NCBI chrNW_004955561:1,282,970...1,292,710
Ensembl chrNW_004955561:1,282,970...1,294,972
JBrowse link
G Gcm1 glial cells missing transcription factor 1 acts_upstream_of_or_within ISO (MGI:5049808|PMID:21558372) MGI PMID:21558372 MGI:5049808 NCBI chrNW_004955411:2,872,758...2,917,154
Ensembl chrNW_004955411:2,898,693...2,917,168
JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor 3 involved_in ISO (PMID:23867755) UniProt PMID:23867755 NCBI chrNW_004955500:6,655,056...6,674,311
Ensembl chrNW_004955500:6,655,056...6,674,311
JBrowse link
regulation of myoblast fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myog myogenin involved_in ISO (MGI:5508727|PMID:21465538) UniProt PMID:21465538 MGI:5508727 NCBI chrNW_004955406:39,099,044...39,102,479
Ensembl chrNW_004955406:39,099,716...39,102,501
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12101
    developmental process 5740
      regulation of developmental process 2383
        regulation of syncytium formation by plasma membrane fusion 32
          modulation by virus of syncytium formation via plasma membrane fusion + 0
          negative regulation of syncytium formation by plasma membrane fusion + 6
          positive regulation of syncytium formation by plasma membrane fusion + 26
          regulation of macrophage fusion + 6
          regulation of myoblast fusion + 22
Path 2
Term Annotations click to browse term
  biological_process 12101
    developmental process 5740
      anatomical structure development 5365
        anatomical structure morphogenesis 2542
          anatomical structure formation involved in morphogenesis 1112
            syncytium formation 61
              syncytium formation by plasma membrane fusion 59
                regulation of syncytium formation by plasma membrane fusion 32
                  modulation by virus of syncytium formation via plasma membrane fusion + 0
                  negative regulation of syncytium formation by plasma membrane fusion + 6
                  positive regulation of syncytium formation by plasma membrane fusion + 26
                  regulation of macrophage fusion + 6
                  regulation of myoblast fusion + 22
paths to the root