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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of syncytium formation by plasma membrane fusion
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Accession:GO:0060142 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.


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negative regulation of macrophage fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Stat1 signal transducer and activator of transcription 1 acts_upstream_of_or_within ISO MGI:1861949 (MGI:5462143|PMID:22865856) RGD PMID:22865856 MGI:5462143 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
negative regulation of myoblast fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cflar CASP8 and FADD-like apoptosis regulator involved_in ISO (MGI:5707584|PMID:21364645) RGD PMID:21364645 MGI:5707584 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 acts_upstream_of_or_within ISO (MGI:5532227|PMID:23844157) RGD PMID:23844157 MGI:5532227 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Il36g interleukin 36, gamma acts_upstream_of_or_within ISO (MGI:5532227|PMID:23844157) RGD PMID:23844157 MGI:5532227 NCBI chr 3:6,948,323...6,954,485
Ensembl chr 3:6,948,297...6,954,480 		JBrowse link
G Tmem182 transmembrane protein 182 involved_in ISO (MGI:6810807|PMID:34427057) RGD PMID:34427057 MGI:6810807 NCBI chr 9:43,059,432...43,111,318
Ensembl chr 9:43,059,439...43,111,317 		JBrowse link
negative regulation of syncytium formation by plasma membrane fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfe2 nuclear factor, erythroid 2 acts_upstream_of_or_within ISO MGI:108045 (MGI:5049808|PMID:21558372) RGD PMID:21558372 MGI:5049808 NCBI chr 7:134,382,758...134,395,364
Ensembl chr 7:134,382,761...134,390,108 		JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor 3 involved_in ISO
IEA		 (PMID:23867755)
GO_REF:0000107		 RGD
Ensembl		 PMID:23867755 GO_REF:0000107 NCBI chr 7:128,875,772...128,898,203
Ensembl chr 7:128,875,773...128,898,521 		JBrowse link
positive regulation of macrophage fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam9 ADAM metallopeptidase domain 9 involved_in ISO (PMID:11831872) RGD PMID:11831872 NCBI chr16:67,022,538...67,101,647
Ensembl chr16:67,022,655...67,100,917 		JBrowse link
G Dcstamp dendrocyte expressed seven transmembrane protein acts_upstream_of_or_within
involved_in		 ISO MGI:1921864 (MGI:5462143|PMID:22865856)
(MGI:3588832|PMID:16061724), (MGI:5426135|PMID:16937266)		 RGD PMID:16061724 PMID:16937266 PMID:22865856 MGI:3588832 MGI:5426135 MGI:5462143 NCBI chr 7:70,807,455...70,822,067
Ensembl chr 7:70,807,581...70,822,078 		JBrowse link
G Ocstamp osteoclast stimulatory transmembrane protein acts_upstream_of_or_within ISO MGI:1923016 (MGI:5462143|PMID:22865856) RGD PMID:22865856 MGI:5462143 NCBI chr 3:154,131,113...154,141,611
Ensembl chr 3:154,132,328...154,136,991 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6142486|PMID:18957693) RGD PMID:18957693 MGI:6142486 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp involved_in ISO
IBA		 (PMID:18957693)
(MGI:6142486|PMID:18957693)
PMID:21873635		 RGD PMID:18957693 PMID:21873635 MGI:6142486, RGD:13792537 NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848 		JBrowse link
positive regulation of myoblast fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrb1 adhesion G protein-coupled receptor B1 involved_in ISO
IEA		 (MGI:5498642|PMID:23615608)
GO_REF:0000107		 RGD
Ensembl		 PMID:23615608 GO_REF:0000107 MGI:5498642 NCBI chr 7:106,404,827...106,476,902
Ensembl chr 7:106,404,958...106,476,902 		JBrowse link
G Capn2 calpain 2 IMP RGD PMID:7657725 RGD:13792659 NCBI chr13:94,150,244...94,200,969
Ensembl chr13:94,150,240...94,200,969 		JBrowse link
G Cd53 Cd53 molecule involved_in ISS
ISO		 GO_REF:0000024
(MGI:5526919|PMID:22847234)		 UniProt
RGD		 PMID:22847234 GO_REF:0000024 MGI:5526919 NCBI chr 2:194,352,139...194,399,668
Ensembl chr 2:194,352,139...194,399,657 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 acts_upstream_of_or_within ISO (MGI:5532227|PMID:23844157) RGD PMID:23844157 MGI:5532227 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 acts_upstream_of_or_within ISO (MGI:5532227|PMID:23844157) RGD PMID:23844157 MGI:5532227 NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435 		JBrowse link
G Ehd1 EH-domain containing 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5487527|PMID:21177873)		 UniProt
RGD		 PMID:21177873 GO_REF:0000024 MGI:5487527 NCBI chr 1:203,579,850...203,602,226
Ensembl chr 1:203,579,869...203,602,212 		JBrowse link
G Ehd2 EH-domain containing 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5487527|PMID:21177873)		 UniProt
RGD		 PMID:21177873 GO_REF:0000024 MGI:5487527 NCBI chr 1:76,639,568...76,658,747
Ensembl chr 1:76,637,482...76,658,783 		JBrowse link
G Flot1 flotillin 1 involved_in ISO (PMID:24046456)
(MGI:5634880|PMID:24046456)		 RGD PMID:24046456 MGI:5634880 NCBI chr20:2,917,864...2,927,993
Ensembl chr20:2,917,137...2,927,978 		JBrowse link
G Flt3lg Fms related receptor tyrosine kinase 3 ligand acts_upstream_of_or_within ISO (MGI:5532227|PMID:23844157) RGD PMID:23844157 MGI:5532227 NCBI chr 1:95,615,056...95,620,463
Ensembl chr 1:95,609,370...95,620,463 		JBrowse link
G Gdf15 growth differentiation factor 15 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:5532227|PMID:23844157)		 Ensembl
RGD		 PMID:23844157 GO_REF:0000107 MGI:5532227 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055 		JBrowse link
G Il4 interleukin 4 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:1857194 (MGI:3621675|PMID:12757709)		 RGD PMID:12757709 PMID:21873635 MGI:3621675, RGD:13792537 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il4r interleukin 4 receptor acts_upstream_of_or_within ISO MGI:1861951 (MGI:3621675|PMID:12757709) RGD PMID:12757709 MGI:3621675 NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:5526919|PMID:22847234)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:22847234 GO_REF:0000024 GO_REF:0000107 MGI:5526919 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Myod1 myogenic differentiation 1 involved_in ISO
IEA		 (PMID:10672515)
GO_REF:0000107		 RGD
Ensembl		 PMID:10672515 GO_REF:0000107 NCBI chr 1:96,884,864...96,887,574
Ensembl chr 1:96,884,948...96,887,554 		JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 acts_upstream_of_or_within ISO MGI:2182740 (MGI:3621675|PMID:12757709) RGD PMID:12757709 MGI:3621675 NCBI chr 3:157,195,970...157,328,640
Ensembl chr 3:157,198,872...157,328,325 		JBrowse link
G Ripor2 RHO family interacting cell polarization regulator 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17150207)		 UniProt
RGD		 PMID:17150207 GO_REF:0000024 NCBI chr17:40,323,748...40,547,482
Ensembl chr17:40,323,867...40,548,092 		JBrowse link
G Scgb3a1 secretoglobin, family 3A, member 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:5532227|PMID:23844157)		 RGD PMID:23844157 PMID:21873635 MGI:5532227, RGD:13792537 NCBI chr10:33,968,059...33,969,366
Ensembl chr10:33,968,059...33,969,476 		JBrowse link
G Tnfsf14 TNF superfamily member 14 acts_upstream_of_or_within ISO (MGI:5532227|PMID:23844157) RGD PMID:23844157 MGI:5532227 NCBI chr 9:2,068,295...2,073,128
Ensembl chr 9:2,069,104...2,073,216 		JBrowse link
positive regulation of syncytium formation by plasma membrane fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk1 calcium/calmodulin-dependent protein kinase I involved_in ISO
IEA		 (PMID:23867755)
GO_REF:0000107		 RGD
Ensembl		 PMID:23867755 GO_REF:0000107 NCBI chr 4:146,481,196...146,492,039
Ensembl chr 4:146,481,196...146,492,081 		JBrowse link
G Gcm1 glial cells missing transcription factor 1 acts_upstream_of_or_within ISO (MGI:5049808|PMID:21558372)
MGI:97308 (MGI:5049808|PMID:21558372)		 RGD PMID:21558372 MGI:5049808 NCBI chr 8:78,925,687...78,938,924
Ensembl chr 8:78,925,687...78,938,924 		JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor 3 involved_in ISO
IEA		 (PMID:23867755)
GO_REF:0000107		 RGD
Ensembl		 PMID:23867755 GO_REF:0000107 NCBI chr 7:128,875,772...128,898,203
Ensembl chr 7:128,875,773...128,898,521 		JBrowse link
regulation of myoblast fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myog myogenin involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5508727|PMID:21465538)		 UniProt
Ensembl
RGD		 PMID:21465538 GO_REF:0000024 GO_REF:0000107 MGI:5508727 NCBI chr13:45,745,455...45,748,044
Ensembl chr13:45,745,436...45,748,039 		JBrowse link
G Plekho1 pleckstrin homology domain containing O1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:183,544,487...183,552,928
Ensembl chr 2:183,544,499...183,552,785 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19574
    developmental process 6911
      regulation of developmental process 2771
        regulation of syncytium formation by plasma membrane fusion 34
          modulation by virus of syncytium formation via plasma membrane fusion + 0
          negative regulation of syncytium formation by plasma membrane fusion + 7
          positive regulation of syncytium formation by plasma membrane fusion + 26
          regulation of macrophage fusion + 6
          regulation of myoblast fusion + 24
Path 2
Term Annotations click to browse term
  biological_process 19574
    developmental process 6911
      anatomical structure development 6438
        anatomical structure morphogenesis 2957
          anatomical structure formation involved in morphogenesis 1352
            syncytium formation 67
              syncytium formation by plasma membrane fusion 65
                regulation of syncytium formation by plasma membrane fusion 34
                  modulation by virus of syncytium formation via plasma membrane fusion + 0
                  negative regulation of syncytium formation by plasma membrane fusion + 7
                  positive regulation of syncytium formation by plasma membrane fusion + 26
                  regulation of macrophage fusion + 6
                  regulation of myoblast fusion + 24
paths to the root