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ONTOLOGY REPORT - ANNOTATIONS

Term:membrane hyperpolarization
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Accession:GO:0060081 term browser browse the term
Definition:The process in which membrane potential increases with respect to its steady-state potential, usually from negative potential to a more negative potential. For example, during the repolarization phase of an action potential the membrane potential often becomes more negative or hyperpolarized before returning to the steady-state resting potential.


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membrane hyperpolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 IMP RGD PMID:17001300 RGD:6903222 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837 		JBrowse link
G Cacng2 calcium voltage-gated channel auxiliary subunit gamma 2 acts_upstream_of_or_within ISO MGI:1856548 (PMID:9065835) RGD PMID:9065835 NCBI chr 7:109,572,838...109,698,516
Ensembl chr 7:109,574,459...109,697,227 		JBrowse link
G Casp1 caspase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:23028046)		 Ensembl
RGD		 PMID:23028046 GO_REF:0000107 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Cftr CF transmembrane conductance regulator involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:21976599)
GO_REF:0000107
(MGI:5429843|PMID:21976599)		 UniProt
RGD
Ensembl		 PMID:21976599 GO_REF:0000024 GO_REF:0000107 MGI:5429843 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756 		JBrowse link
G Cntf ciliary neurotrophic factor IDA in fast-twitch flexor digitorum brevis muscle fibers RGD PMID:15831538 RGD:1626125 NCBI chr 1:209,887,854...209,889,877
Ensembl chr 1:209,887,854...209,889,877 		JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 involved_in ISO (PMID:16236819) RGD PMID:16236819 NCBI chr 4:159,354,689...159,358,173
Ensembl chr 4:159,350,097...159,357,697 		JBrowse link
G Kcnc2 potassium voltage-gated channel subfamily C member 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17761775)		 UniProt
RGD		 PMID:17761775 GO_REF:0000024 NCBI chr 7:47,700,035...47,883,979
Ensembl chr 7:47,700,288...47,883,968 		JBrowse link
G Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 IMP RGD PMID:17091490 RGD:2326042 NCBI chr13:84,802,026...84,835,383
Ensembl chr13:84,802,009...84,835,461 		JBrowse link
G Kcnq2 potassium voltage-gated channel subfamily Q member 2 acts_upstream_of_or_within ISO MGI:3604594 RGD MGI:62459 NCBI chr 3:168,194,776...168,253,831
Ensembl chr 3:168,195,357...168,275,071 		JBrowse link
G Kcnq3 potassium voltage-gated channel subfamily Q member 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3830636 (PMID:19060215)		 Ensembl
RGD		 PMID:19060215 GO_REF:0000107 NCBI chr 7:97,730,219...98,025,652
Ensembl chr 7:97,730,465...98,025,653 		JBrowse link
G Kctd7 potassium channel tetramerization domain containing 7 involved_in ISO
IBA		 (MGI:6107400|PMID:27742667)
(PMID:27742667)
GO_REF:0000033		 RGD
GO_Central		 PMID:27742667 GO_REF:0000033 MGI:6107400 NCBI chr12:26,520,969...26,532,327
Ensembl chr12:26,523,142...26,532,138 		JBrowse link
G Park7 Parkinsonism associated deglycase acts_upstream_of_or_within ISO MGI:3579140 (PMID:16624565) RGD PMID:16624565 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Prkcz protein kinase C, zeta IMP RGD PMID:15062979 RGD:1642685 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367 		JBrowse link
G Slc26a3 solute carrier family 26 member 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21976599)
(MGI:5429843|PMID:21976599)		 UniProt
RGD		 PMID:21976599 GO_REF:0000024 MGI:5429843 NCBI chr 6:48,023,892...48,064,829
Ensembl chr 6:48,023,892...48,064,772 		JBrowse link
negative regulation of membrane hyperpolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crtc1 CREB regulated transcription coactivator 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:23223304)		 Ensembl
RGD		 PMID:23223304 GO_REF:0000107 NCBI chr16:18,988,197...19,046,914
Ensembl chr16:18,988,250...19,043,381 		JBrowse link
G Rbfox2 RNA binding fox-1 homolog 2 IMP RGD PMID:28993448 RGD:329848961 NCBI chr 7:108,810,627...109,054,420
Ensembl chr 7:108,810,628...109,054,691 		JBrowse link
G Sod2 superoxide dismutase 2 IMP RGD PMID:20529999 RGD:27095884 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
positive regulation of membrane hyperpolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen involved_in ISO (PMID:15803439), (PMID:17703433) RGD PMID:15803439 PMID:17703433 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 IMP RGD PMID:30408474 RGD:26923909 NCBI chr 2:49,495,771...49,899,983
Ensembl chr 2:49,495,771...49,899,774 		JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 involved_in ISO (PMID:25139746) RGD PMID:25139746 NCBI chr15:302,480...1,007,675
Ensembl chr15:302,214...1,001,198 		JBrowse link
G Trpc1 transient receptor potential cation channel, subfamily C, member 1 involved_in ISO (PMID:25139746) RGD PMID:25139746 NCBI chr 8:96,263,322...96,314,220
Ensembl chr 8:96,263,329...96,314,276 		JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 involved_in ISO (PMID:25139746) RGD PMID:25139746 NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517 		JBrowse link
regulation of membrane hyperpolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 IDA RGD PMID:15024042 RGD:13514097 NCBI chr 7:129,784,799...129,797,074
Ensembl chr 7:129,783,674...129,797,074 		JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 IMP RGD PMID:22884333 RGD:9686419 NCBI chr 2:49,495,771...49,899,983
Ensembl chr 2:49,495,771...49,899,774 		JBrowse link
G Trpc5 transient receptor potential cation channel, subfamily C, member 5 IMP RGD PMID:21179559 RGD:10043832 NCBI chr  X:107,946,163...108,230,991
Ensembl chr  X:107,939,131...108,230,991 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20133
    biological regulation 13561
      regulation of biological quality 3390
        regulation of membrane potential 548
          membrane hyperpolarization 24
            negative regulation of membrane hyperpolarization 3
            positive regulation of membrane hyperpolarization 5
            regulation of membrane hyperpolarization + 10
paths to the root