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ONTOLOGY REPORT - ANNOTATIONS


Term:synapse maturation
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Accession:GO:0060074 term browser browse the term
Definition:The process that organizes a synapse so that it attains its fully functional state. Synaptic maturation plays a critical role in the establishment of effective synaptic connections in early development.
Synonyms:exact_synonym: synaptic maturation



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synapse maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase involved_in ISO (MGI:5789815|PMID:27335408) SynGO PMID:27335408 MGI:5789815 NCBI chr 1:154,586,423...154,711,621
Ensembl chr 1:158,280,994...158,313,915
JBrowse link
G BCAN brevican involved_in ISO (MGI:6114457|PMID:28712654) SynGO PMID:28712654 MGI:6114457 NCBI chr 1:131,985,310...132,003,068
Ensembl chr 1:135,808,783...135,826,344
JBrowse link
G CHRDL1 chordin like 1 involved_in ISO (MGI:6269241|PMID:30344043) MGI PMID:30344043 MGI:6269241 NCBI chr  X:99,781,730...99,915,778
Ensembl chr  X:110,251,525...110,375,289
JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 involved_in ISO (MGI:5576986|PMID:24487234) ARUK-UCL PMID:24487234 MGI:5576986 NCBI chr 3:39,158,346...39,176,604
Ensembl chr 3:39,440,955...39,457,219
JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 ISO RGD PMID:17521571 RGD:2289990 NCBI chr2B:98,625,630...99,795,371
Ensembl chr2B:217,069,644...218,272,006
JBrowse link
G IGSF21 immunoglobin superfamily member 21 involved_in ISO (MGI:5925767|PMID:28864826) UniProt PMID:28864826 MGI:5925767 NCBI chr 1:17,063,522...17,336,389
Ensembl chr 1:18,116,451...18,387,611
JBrowse link
G NEFL neurofilament light chain involved_in ISO (MGI:5609100|PMID:25232125) SynGO PMID:25232125 MGI:5609100 NCBI chr 8:24,218,510...24,224,627
Ensembl chr 8:21,134,533...21,140,694
JBrowse link
G NFIA nuclear factor I A acts_upstream_of_or_within ISO (MGI:5471880|PMID:23407945) MGI PMID:23407945 MGI:5471880 NCBI chr 1:60,331,945...60,713,729
Ensembl chr 1:61,938,945...62,526,753
JBrowse link
G PALM paralemmin involved_in ISO (MGI:5009384|PMID:18287537) UniProt PMID:18287537 MGI:5009384 NCBI chr19:386,417...427,178
Ensembl chr19:693,853...713,465
JBrowse link
G PFN1 profilin 1 involved_in ISO (MGI:5766825|PMID:26951674) SynGO PMID:26951674 MGI:5766825 NCBI chr17:4,993,853...4,996,811
Ensembl chr17:4,981,765...4,985,022
JBrowse link
G PTEN phosphatase and tensin homolog involved_in ISO (MGI:3772418|PMID:18082964) CACAO PMID:18082964 MGI:3772418 NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605
JBrowse link
G SEZ6 seizure related 6 homolog acts_upstream_of_or_within ISO (MGI:3654399|PMID:16814779) MGI PMID:16814779 MGI:3654399 NCBI chr17:27,768,229...27,819,257
Ensembl chr17:28,301,359...28,327,354
JBrowse link
G SEZ6L seizure related 6 homolog like acts_upstream_of_or_within ISO (MGI:3654399|PMID:16814779) MGI PMID:16814779 MGI:3654399 NCBI chr22:7,230,597...7,445,397
Ensembl chr22:25,077,259...25,163,881
JBrowse link
G SEZ6L2 seizure related 6 homolog like 2 acts_upstream_of_or_within ISO (MGI:3654399|PMID:16814779) MGI PMID:16814779 MGI:3654399 Ensembl chr16:30,240,276...30,267,689 JBrowse link
G SHANK1 SH3 and multiple ankyrin repeat domains 1 involved_in ISO PMID:18287537 UniProt PMID:18287537 RGD:8553517 NCBI chr19:47,623,474...47,684,476
Ensembl chr19:56,526,577...56,580,442
JBrowse link
G SYBU syntabulin ISO RGD PMID:19828815 RGD:13217418 NCBI chr 8:106,223,046...106,340,418
Ensembl chr 8:108,368,117...108,483,927
JBrowse link
negative regulation of synapse maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARHGEF15 Rho guanine nucleotide exchange factor 15 involved_in ISO (MGI:4881358|PMID:21029865) UniProt PMID:21029865 MGI:4881358 NCBI chr17:43,336,764...43,349,787
Ensembl chr17:48,070,223...48,082,499
JBrowse link
G NEUROD2 neuronal differentiation 2 involved_in ISO (MGI:5009363|PMID:19900895) UniProt PMID:19900895 MGI:5009363 NCBI chr17:17,680,415...17,685,053 JBrowse link
G NFATC4 nuclear factor of activated T cells 4 acts_upstream_of_or_within ISO (MGI:5471880|PMID:23407945) MGI PMID:23407945 MGI:5471880 NCBI chr14:5,141,699...5,156,021
Ensembl chr14:23,266,702...23,279,249
JBrowse link
positive regulation of synapse maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADGRL1 adhesion G protein-coupled receptor L1 involved_in ISO PMID:21724987 UniProt PMID:21724987 RGD:8553824 NCBI chr19:13,713,395...13,772,360
Ensembl chr19:14,439,730...14,475,877
JBrowse link
G ANAPC2 anaphase promoting complex subunit 2 involved_in ISO (MGI:5009363|PMID:19900895) UniProt PMID:19900895 MGI:5009363 NCBI chr 9:108,234,949...108,248,227
Ensembl chr 9:137,204,356...137,217,652
JBrowse link
G CAMK2B calcium/calmodulin dependent protein kinase II beta involved_in ISO PMID:12873385 UniProt PMID:12873385 RGD:8553829 NCBI chr 7:44,930,859...45,040,078
Ensembl chr 7:45,001,267...45,110,342
JBrowse link
G CDC20 cell division cycle 20 involved_in ISO (MGI:5009363|PMID:19900895) UniProt PMID:19900895 MGI:5009363 NCBI chr 1:42,660,338...42,664,618
Ensembl chr 1:44,039,971...44,044,497
JBrowse link
G DAB2IP DAB2 interacting protein involved_in ISO (MGI:5486089|PMID:23326475) UniProt PMID:23326475 MGI:5486089 NCBI chr 9:92,696,798...92,912,425
Ensembl chr 9:121,143,457...121,254,336
JBrowse link
G HNRNPK heterogeneous nuclear ribonucleoprotein K ISO RGD PMID:22102872 RGD:10002783 NCBI chr 9:40,898,593...40,911,159
Ensembl chr 9:83,324,238...83,336,756
JBrowse link
G NEURL1 neuralized E3 ubiquitin protein ligase 1 involved_in ISO (MGI:5300629|PMID:22153079) UniProt PMID:22153079 MGI:5300629 NCBI chr10:100,093,614...100,192,485 JBrowse link
G NEUROD2 neuronal differentiation 2 involved_in ISO (MGI:3621523|PMID:16504944) UniProt PMID:16504944 MGI:3621523 NCBI chr17:17,680,415...17,685,053 JBrowse link
G NRXN1 neurexin 1 acts_upstream_of_or_within ISO (MGI:4365478|PMID:19567877) MGI PMID:19567877 MGI:4365478 NCBI chr2A:50,063,398...51,178,659
Ensembl chr2A:50,985,067...52,091,277
JBrowse link
G RELN reelin involved_in ISO (MGI:3765383|PMID:17229826) CACAO PMID:17229826 MGI:3765383 NCBI chr 7:95,464,285...95,984,813
Ensembl chr 7:108,208,344...108,728,037
JBrowse link
protein-containing complex assembly involved in synapse maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NRXN1 neurexin 1 involved_in ISO (MGI:2665153|PMID:12796785) BHF-UCL PMID:12796785 MGI:2665153 NCBI chr2A:50,063,398...51,178,659
Ensembl chr2A:50,985,067...52,091,277
JBrowse link
regulation of synapse maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLSTN1 calsyntenin 1 involved_in ISO (MGI:5581343|PMID:24966372) SynGO PMID:24966372 MGI:5581343 NCBI chr 1:8,495,571...8,591,613
Ensembl chr 1:9,724,743...9,774,760
JBrowse link
G DISC1 DISC1 scaffold protein involved_in ISO (MGI:4441254|PMID:17825401) UniProt PMID:17825401 MGI:4441254 NCBI chr 1:207,180,513...207,594,684
Ensembl chr 1:212,265,520...212,612,079
JBrowse link
G NRG2 neuregulin 2 involved_in ISO PMID:26674872 SynGO PMID:26674872 RGD:11070025 NCBI chr 5:135,212,496...135,411,469 JBrowse link
G YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta involved_in ISO (PMID:16959763) SynGO PMID:16959763 NCBI chr 8:97,560,251...97,595,117
Ensembl chr 8:99,730,393...99,762,990
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12786
    developmental process 5966
      developmental maturation 324
        synapse maturation 32
          cell-cell adhesion involved in synapse maturation 0
          negative regulation of synapse maturation 3
          positive regulation of synapse maturation + 10
          protein-containing complex assembly involved in synapse maturation 1
          regulation of synapse maturation + 16
Path 2
Term Annotations click to browse term
  biological_process 12786
    cellular process 11938
      cellular component organization or biogenesis 5052
        cellular component organization 4967
          cell junction organization 700
            synapse organization 469
              synapse maturation 32
                cell-cell adhesion involved in synapse maturation 0
                negative regulation of synapse maturation 3
                positive regulation of synapse maturation + 10
                protein-containing complex assembly involved in synapse maturation 1
                regulation of synapse maturation + 16
paths to the root