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ONTOLOGY REPORT - ANNOTATIONS


Term:synapse maturation
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Accession:GO:0060074 term browser browse the term
Definition:The process that organizes a synapse so that it attains its fully functional state. Synaptic maturation plays a critical role in the establishment of effective synaptic connections in early development.
Synonyms:exact_synonym: synaptic maturation



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synapse maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase involved_in ISO (MGI:5789815|PMID:27335408) RGD PMID:27335408 MGI:5789815 NCBI chr13:68,673,702...68,839,742
Ensembl chr13:68,673,722...68,839,742
JBrowse link
G Bcan brevican involved_in IEA
ISO
GO_REF:0000107
(MGI:6114457|PMID:28712654)
Ensembl
RGD
PMID:28712654 GO_REF:0000107 MGI:6114457 NCBI chr 2:173,454,479...173,467,717
Ensembl chr 2:173,454,482...173,467,460
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 involved_in ISO (MGI:5576986|PMID:24487234) RGD PMID:24487234 MGI:5576986 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 IMP RGD PMID:17521571 RGD:2289990 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595
JBrowse link
G Igsf21 immunoglobin superfamily, member 21 involved_in ISS
ISO
GO_REF:0000024
(MGI:5925767|PMID:28864826)
UniProt
RGD
PMID:28864826 GO_REF:0000024 MGI:5925767 NCBI chr 5:152,287,834...152,512,174
Ensembl chr 5:152,287,835...152,512,174
JBrowse link
G Nefl neurofilament light chain involved_in ISO (MGI:5609100|PMID:25232125) RGD PMID:25232125 MGI:5609100 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793
JBrowse link
G Nfia nuclear factor I/A involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5471880|PMID:23407945)
Ensembl
RGD
PMID:23407945 GO_REF:0000107 MGI:5471880 NCBI chr 5:112,436,655...112,781,878
Ensembl chr 5:112,436,644...112,775,885
JBrowse link
G Palm paralemmin involved_in ISO (MGI:5009384|PMID:18287537) RGD PMID:18287537 MGI:5009384 NCBI chr 7:9,886,634...9,912,389
Ensembl chr 7:9,886,643...9,912,555
JBrowse link
G Pfn1 profilin 1 involved_in ISO (MGI:5766825|PMID:26951674) RGD PMID:26951674 MGI:5766825 NCBI chr10:55,365,263...55,367,968
Ensembl chr10:55,365,262...55,527,631
JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (MGI:3772418|PMID:18082964) RGD PMID:18082964 MGI:3772418 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Sez6 seizure related 6 homolog acts_upstream_of_or_within ISO MGI:1935121|MGI:2385295 (MGI:3654399|PMID:16814779) RGD PMID:16814779 MGI:3654399 NCBI chr10:62,818,931...62,868,686
Ensembl chr10:62,819,069...62,868,671
JBrowse link
G Sez6l seizure related 6 homolog like acts_upstream_of_or_within ISO MGI:104745|MGI:2385295 (MGI:3654399|PMID:16814779) RGD PMID:16814779 MGI:3654399 NCBI chr12:44,064,628...44,221,815
Ensembl chr12:44,064,935...44,219,663
JBrowse link
G Sez6l2 seizure related 6 homolog like 2 acts_upstream_of_or_within ISO MGI:104745|MGI:1935121 (MGI:3654399|PMID:16814779) RGD PMID:16814779 MGI:3654399 NCBI chr 1:181,557,109...181,577,456
Ensembl chr 1:181,557,109...181,577,456
JBrowse link
G Shank1 SH3 and multiple ankyrin repeat domains 1 involved_in IDA PMID:18287537 UniProt PMID:18287537 RGD:8553517 NCBI chr 1:94,807,879...94,857,356
Ensembl chr 1:94,808,276...94,855,824
JBrowse link
G Sybu syntabulin involved_in IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:19828815 PMID:21873635 RGD:13217418, RGD:13792537 NCBI chr 7:75,847,000...75,948,919
Ensembl chr 7:75,847,003...75,948,828
JBrowse link
negative regulation of synapse maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef15 Rho guanine nucleotide exchange factor 15 involved_in ISO (MGI:4881358|PMID:21029865) RGD PMID:21029865 MGI:4881358 NCBI chr10:53,650,521...53,662,914
Ensembl chr10:53,650,553...53,663,913
JBrowse link
G Neurod2 neuronal differentiation 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:5009363|PMID:19900895)
UniProt
RGD
PMID:19900895 GO_REF:0000024 MGI:5009363 NCBI chr10:83,323,801...83,327,986
Ensembl chr10:83,324,442...83,327,986
JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 acts_upstream_of_or_within ISO (MGI:5471880|PMID:23407945) RGD PMID:23407945 MGI:5471880 NCBI chr15:29,286,998...29,314,610
Ensembl chr15:29,305,535...29,314,610
JBrowse link
positive regulation of synapse maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrl1 adhesion G protein-coupled receptor L1 involved_in IDA PMID:21724987 UniProt PMID:21724987 RGD:8553824 NCBI chr19:24,202,405...24,244,137
Ensembl chr19:24,204,360...24,244,139
JBrowse link
G Anapc2 anaphase promoting complex subunit 2 involved_in ISO (MGI:5009363|PMID:19900895) RGD PMID:19900895 MGI:5009363 NCBI chr 3:8,086,434...8,098,182
Ensembl chr 3:8,086,462...8,098,178
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta involved_in IMP PMID:12873385 UniProt PMID:12873385 RGD:8553829 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994
JBrowse link
G Cdc20 cell division cycle 20 involved_in ISS
ISO
GO_REF:0000024
(MGI:5009363|PMID:19900895)
UniProt
RGD
PMID:19900895 GO_REF:0000024 MGI:5009363 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
JBrowse link
G Dab2ip DAB2 interacting protein involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:5486089|PMID:23326475)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:23326475 GO_REF:0000024 GO_REF:0000107 MGI:5486089 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280
JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K IMP RGD PMID:22102872 RGD:10002783 NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997
JBrowse link
G Neurl1 neuralized E3 ubiquitin protein ligase 1 involved_in ISO (MGI:5300629|PMID:22153079) RGD PMID:22153079 MGI:5300629 NCBI chr 1:246,066,642...246,152,890
Ensembl chr 1:246,067,100...246,152,903
JBrowse link
G Neurod2 neuronal differentiation 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:3621523|PMID:16504944)
UniProt
RGD
PMID:16504944 GO_REF:0000024 MGI:3621523 NCBI chr10:83,323,801...83,327,986
Ensembl chr10:83,324,442...83,327,986
JBrowse link
G Nrxn1 neurexin 1 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(MGI:4365478|PMID:19567877)
BHF-UCL
RGD
PMID:19567877 GO_REF:0000024 MGI:4365478 NCBI chr 6:3,177,788...4,323,848
Ensembl chr 6:3,177,897...4,322,710
JBrowse link
G Reln reelin involved_in IEA
ISO
GO_REF:0000107
(MGI:3765383|PMID:17229826)
Ensembl
RGD
PMID:17229826 GO_REF:0000107 MGI:3765383 NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211
JBrowse link
protein-containing complex assembly involved in synapse maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nrxn1 neurexin 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:2665153|PMID:12796785)
BHF-UCL
RGD
PMID:12796785 GO_REF:0000024 MGI:2665153 NCBI chr 6:3,177,788...4,323,848
Ensembl chr 6:3,177,897...4,322,710
JBrowse link
regulation of synapse maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clstn1 calsyntenin 1 involved_in ISO (MGI:5581343|PMID:24966372) RGD PMID:24966372 MGI:5581343 NCBI chr 5:160,031,235...160,094,585
Ensembl chr 5:160,031,308...160,094,583
JBrowse link
G Disc1 DISC1 scaffold protein involved_in ISO (MGI:4441254|PMID:17825401) RGD PMID:17825401 MGI:4441254 NCBI chr19:53,014,201...53,223,617
Ensembl chr19:53,014,616...53,219,778
JBrowse link
G Nrg2 neuregulin 2 involved_in IDA
IMP
PMID:26674872 SynGO PMID:26674872 PMID:26674872 RGD:11070025, RGD:11070025 NCBI chr18:27,619,635...27,798,505
Ensembl chr18:27,619,661...27,798,505
JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta involved_in ISO
IEA
(PMID:16959763)
GO_REF:0000107
RGD
Ensembl
PMID:16959763 GO_REF:0000107 NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19391
    developmental process 6775
      developmental maturation 349
        synapse maturation 31
          cell-cell adhesion involved in synapse maturation 0
          negative regulation of synapse maturation 3
          positive regulation of synapse maturation + 10
          protein-containing complex assembly involved in synapse maturation 1
          regulation of synapse maturation + 16
Path 2
Term Annotations click to browse term
  biological_process 19391
    cellular process 18252
      cellular component organization or biogenesis 6492
        cellular component organization 6250
          cell junction organization 798
            synapse organization 512
              synapse maturation 31
                cell-cell adhesion involved in synapse maturation 0
                negative regulation of synapse maturation 3
                positive regulation of synapse maturation + 10
                protein-containing complex assembly involved in synapse maturation 1
                regulation of synapse maturation + 16
paths to the root