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ONTOLOGY REPORT - ANNOTATIONS


Term:canonical Wnt signaling pathway
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Accession:GO:0060070 term browser browse the term
Definition:The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
Synonyms:exact_synonym: Wnt receptor signaling pathway through beta-catenin;   Wnt receptor signaling pathway via beta-catenin;   Wnt receptor signalling pathway through beta-catenin;   canonical Wnt receptor signaling pathway;   canonical Wnt-activated signaling pathway
 narrow_synonym: frizzled-1 receptor signaling pathway


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canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway acts_upstream_of_or_within ISO MGI:1856318 (MGI:3655896|PMID:16887818) RGD PMID:16887818 MGI:3655896 NCBI chr18:27,011,710...27,106,323
Ensembl chr18:27,047,382...27,105,531
JBrowse link
G Axin1 axin 1 acts_upstream_of_or_within ISO (MGI:3758508|PMID:10937998), (MGI:3835914|PMID:19075000) RGD PMID:10937998 PMID:19075000 MGI:3758508 MGI:3835914
G Bcl9 BCL9, transcription coactivator involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1933114|MGI:98956 (MGI:4368064|PMID:19699733)
RGD PMID:19699733, PMID:21873635 MGI:4368064, RGD:13792537 NCBI chr 2:199,334,644...199,420,083
Ensembl chr 2:199,334,664...199,354,793
JBrowse link
G Bcl9l BCL9 like involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1924828|MGI:98956 (MGI:4368064|PMID:19699733)
RGD PMID:19699733, PMID:21873635 MGI:4368064, RGD:13792537 NCBI chr 8:48,805,684...48,835,794
Ensembl chr 8:48,805,684...48,834,312
JBrowse link
G Csnk1e casein kinase 1, epsilon involved_in ISO UniProtKB:O14640|UniProtKB:Q92837 (PMID:12556519), (PMID:14722104) RGD PMID:12556519 PMID:14722104 NCBI chr 7:120,651,976...120,675,559
Ensembl chr 7:120,651,881...120,672,359
JBrowse link
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:109330|MGI:1261834|MGI:2148567|MGI:2446084|MGI:3577106|MGI:98954|MGI:98957 (MGI:2386811|PMID:12235125), (MGI:2446944|PMID:12464179), (MGI:2662628|PMID:12717450), (MGI:3577701|PMID:15781477), (MGI:3690195|PMID:16678101), (MGI:3701031|PMID:16818445), (MGI:3821953|PMID:19060336), (MGI:4355652|PMID:19619491), (MGI:4359548|PMID:19690384), (MGI:4360856|PMID:19686689), (MGI:4454604|PMID:20454446), (MGI:6453919|PMID:31222549)
(MGI:3054506|PMID:15314168), (MGI:5571208|PMID:24681597), (MGI:5770063|PMID:21752258)
(PMID:10644691), (PMID:12154096), (PMID:12937339), (PMID:18193033), (PMID:19187541)
BHF-UCL
RGD
PMID:10644691 PMID:12154096 PMID:12235125 PMID:12464179 PMID:12717450 PMID:12937339 PMID:15314168 PMID:15781477 PMID:16678101 PMID:16818445 PMID:18193033 PMID:19060336 PMID:19187541 PMID:19619491 PMID:19686689 PMID:19690384 PMID:20454446 PMID:21752258 PMID:24681597 PMID:31222549 GO_REF:0000024 MGI:2386811 MGI:2446944 MGI:2662628 MGI:3054506 MGI:3577701 MGI:3690195 MGI:3701031 MGI:3821953 MGI:4355652 MGI:4359548 MGI:4360856 MGI:4454604 MGI:5571208 MGI:5770063 MGI:6453919 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Dact1 dishevelled-binding antagonist of beta-catenin 1 NOT|involved_in ISO (MGI:4457465|PMID:20145239) RGD PMID:20145239 MGI:4457465 NCBI chr 6:93,740,440...93,751,003
Ensembl chr 6:93,740,586...93,749,809
JBrowse link
G Disc1 DISC1 scaffold protein involved_in ISO (MGI:4821185|PMID:20624590) RGD PMID:20624590 MGI:4821185 NCBI chr19:57,818,838...58,069,992
Ensembl chr19:57,820,260...58,066,152
JBrowse link
G Dixdc1 DIX domain containing 1 involved_in IEA
ISO
ISS
IBA
GO_REF:0000107
(MGI:4821185|PMID:20624590)
GO_REF:0000024
(PMID:21189423)
PMID:21873635
Ensembl
RGD
UniProt
PMID:20624590 PMID:21189423, PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:4821185, RGD:13792537 NCBI chr 8:55,091,232...55,164,636
Ensembl chr 8:55,091,235...55,162,421
JBrowse link
G Dvl1 dishevelled segment polarity protein 1 involved_in ISO
IBA
UniProtKB:P49674|UniProtKB:P51141|UniProtKB:Q92837 (PMID:11113207), (PMID:12556519), (PMID:14747478), (PMID:17593335), (PMID:18093802)
MGI:1351660|MGI:1861437|MGI:2137230|MGI:2673967|MGI:98956 (MGI:1340921|PMID:10409711), (MGI:2158960|PMID:11742004), (MGI:3028275|PMID:14648878), (MGI:3029636|PMID:14966280), (MGI:3821448|PMID:19008950), (MGI:5285137|PMID:21189423), (MGI:5464971|PMID:23074275), (MGI:5693230|PMID:17239604), (MGI:5700301|PMID:18093802)
PMID:21873635
RGD PMID:10409711 PMID:11113207 PMID:11742004 PMID:12556519 PMID:14648878 PMID:14747478 PMID:14966280 PMID:17239604 PMID:17593335 PMID:18093802 PMID:19008950 PMID:21189423 PMID:23074275, PMID:21873635 MGI:1340921 MGI:2158960 MGI:3028275 MGI:3029636 MGI:3821448 MGI:5285137 MGI:5464971 MGI:5693230 MGI:5700301, RGD:13792537 NCBI chr 5:173,295,948...173,308,014
Ensembl chr 5:173,296,270...173,307,945
JBrowse link
G Dvl2 dishevelled segment polarity protein 2 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1351660 (MGI:3721039|PMID:17606995)
MGI:2429760|MGI:98956 (MGI:1340921|PMID:10409711), (MGI:3814781|PMID:18606138), (MGI:3821448|PMID:19008950), (MGI:5285137|PMID:21189423), (MGI:5700301|PMID:18093802), (MGI:82989|PMID:8887313)
(PMID:17593335)
RGD PMID:8887313 PMID:10409711 PMID:17593335 PMID:17606995 PMID:18093802 PMID:18606138 PMID:19008950 PMID:21189423, PMID:21873635 MGI:1340921 MGI:3721039 MGI:3814781 MGI:3821448 MGI:5285137 MGI:5700301 MGI:82989, RGD:13792537 NCBI chr10:56,609,810...56,619,269
Ensembl chr10:56,610,051...56,619,269
JBrowse link
G Dvl3 dishevelled segment polarity protein 3 involved_in IBA
ISO
PMID:21873635
(MGI:5700301|PMID:18093802)
UniProtKB:Q61062 (PMID:10644691), (PMID:17593335), (PMID:18093802), (PMID:20137080)
RGD PMID:10644691 PMID:17593335 PMID:18093802 PMID:20137080, PMID:21873635 MGI:5700301, RGD:13792537 NCBI chr11:84,051,177...84,068,479
Ensembl chr11:84,051,078...84,068,302
JBrowse link
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within ISO (MGI:6199721|PMID:29545125) RGD PMID:29545125 MGI:6199721 NCBI chr 7:92,605,008...92,881,392
Ensembl chr 7:92,605,728...92,882,068
JBrowse link
G Frat1 FRAT regulator of WNT signaling pathway 1 involved_in ISO UniProtKB:O14640|UniProtKB:P49674 (PMID:12556519) RGD PMID:12556519 NCBI chr 1:261,071,965...261,075,244 JBrowse link
G Frzb frizzled-related protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:67,635,604...67,668,772
Ensembl chr 3:67,635,607...67,668,772
JBrowse link
G Fzd1 frizzled class receptor 1 involved_in
acts_upstream_of_or_within
IDA
ISO
IBA
PMID:18945944
MGI:1278315|MGI:2136761|MGI:98961 (MGI:3045675|PMID:15143170), (MGI:3581375|PMID:15923619)
(MGI:5770063|PMID:21752258)
PMID:21873635
PMID:14688793
UniProtKB:P27467 (PMID:10557084), (PMID:11433302), (PMID:14739301), (PMID:28733458)
RGD PMID:10557084 PMID:11433302 PMID:14739301 PMID:15143170 PMID:15923619 PMID:21752258 PMID:28733458, PMID:18945944, PMID:21873635, PMID:14688793 MGI:3045675 MGI:3581375 MGI:5770063, RGD:8554426, RGD:13792537, RGD:8553956 NCBI chr 4:26,470,864...26,475,262
Ensembl chr 4:26,470,864...26,475,262
JBrowse link
G Fzd10 frizzled class receptor 10 involved_in ISO (PMID:28733458) RGD PMID:28733458 NCBI chr12:31,757,407...31,760,604
Ensembl chr12:31,757,407...31,760,604
JBrowse link
G Fzd2 frizzled class receptor 2 involved_in ISO
IEA
IBA
IDA
(PMID:18215320), (PMID:18929644), (PMID:20802536), (PMID:28733458)
GO_REF:0000107
PMID:21873635
PMID:24080158
RGD
Ensembl
PMID:18215320 PMID:18929644 PMID:20802536 PMID:28733458, PMID:21873635, PMID:24080158 GO_REF:0000107, RGD:13792537, RGD:10448946 NCBI chr10:90,550,147...90,552,057
Ensembl chr10:90,550,147...90,552,057
JBrowse link
G Fzd3 frizzled class receptor 3 involved_in IBA
ISO
PMID:21873635
(PMID:20802536)
RGD PMID:20802536, PMID:21873635 RGD:13792537 NCBI chr15:48,601,259...48,670,257
Ensembl chr15:48,601,266...48,670,257
JBrowse link
G Fzd4 frizzled class receptor 4 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
UniProtKB:P27467 (MGI:5700300|PMID:19001373)
MGI:98956|MGI:98962 (MGI:3604165|PMID:16163358), (MGI:3619748|PMID:16115200)
(PMID:14688793), (PMID:20802536), (PMID:28733458)
RGD PMID:14688793 PMID:16115200 PMID:16163358 PMID:19001373 PMID:20802536 PMID:28733458, PMID:21873635 MGI:3604165 MGI:3619748 MGI:5700300, RGD:13792537 NCBI chr 1:153,589,471...153,598,376
Ensembl chr 1:153,589,471...153,598,375
JBrowse link
G Fzd5 frizzled class receptor 5 involved_in IEA
ISO
IBA
GO_REF:0000107
MGI:3583769 (MGI:1929591|PMID:11265645), (MGI:5494335|PMID:23610556)
PMID:21873635
(PMID:11029007), (PMID:12121999), (PMID:12857724), (PMID:15459103), (PMID:24080158), (PMID:28733458), (PMID:9054360)
Ensembl
RGD
PMID:9054360 PMID:11029007 PMID:11265645 PMID:12121999 PMID:12857724 PMID:15459103 PMID:23610556 PMID:24080158 PMID:28733458, PMID:21873635 GO_REF:0000107 MGI:1929591 MGI:5494335, RGD:13792537 NCBI chr 9:71,443,784...71,445,541
Ensembl chr 9:71,443,588...71,445,739
JBrowse link
G Fzd6 frizzled class receptor 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:77,898,329...77,931,034
Ensembl chr 7:77,899,322...77,931,029
JBrowse link
G Fzd7 frizzled class receptor 7 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:18215320), (PMID:18313787), (PMID:19773752), (PMID:20802536), (PMID:28733458)
(MGI:1929591|PMID:11265645)
UniProtKB:P27467 (MGI:5700300|PMID:19001373)
PMID:21873635
RGD PMID:11265645 PMID:18215320 PMID:18313787 PMID:19001373 PMID:19773752 PMID:20802536 PMID:28733458, PMID:21873635 MGI:1929591 MGI:5700300, RGD:13792537 NCBI chr 9:66,305,731...66,308,550
Ensembl chr 9:66,305,731...66,308,550
JBrowse link
G Fzd8 frizzled class receptor 8 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:22138402), (PMID:28733458)
MGI:98956 (MGI:1929591|PMID:11265645), (MGI:3045540|PMID:15064719), (MGI:3045675|PMID:15143170), (MGI:3619748|PMID:16115200), (MGI:3664518|PMID:16543246)
PMID:21873635
RGD PMID:11265645 PMID:15064719 PMID:15143170 PMID:16115200 PMID:16543246 PMID:22138402 PMID:28733458, PMID:21873635 MGI:1929591 MGI:3045540 MGI:3045675 MGI:3619748 MGI:3664518, RGD:13792537 NCBI chr17:62,259,910...62,267,239
Ensembl chr17:62,262,129...62,265,113
Ensembl chr17:62,262,129...62,265,113
JBrowse link
G Fzd9 frizzled class receptor 9 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:24,473,981...24,476,295
Ensembl chr12:24,473,981...24,476,295
JBrowse link
G Gli1 GLI family zinc finger 1 acts_upstream_of_or_within ISO (MGI:5515698|PMID:23740243) RGD PMID:23740243 MGI:5515698 NCBI chr 7:70,620,794...70,633,171
Ensembl chr 7:70,620,766...70,630,338
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta acts_upstream_of_or_within ISO MGI:108559 (MGI:3522557|PMID:15282335), (MGI:3640889|PMID:16815997) RGD PMID:15282335 PMID:16815997 MGI:3522557 MGI:3640889 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Hesx1 HESX homeobox 1 acts_upstream_of_or_within_negative_effect ISO MGI:1931124 (MGI:3790404|PMID:17360769) RGD PMID:17360769 MGI:3790404 NCBI chr16:2,616,538...2,636,708
Ensembl chr16:2,634,603...2,636,708
JBrowse link
G Ins2 insulin 2 acts_upstream_of_or_within ISO MGI:1861437 (MGI:3522557|PMID:15282335) RGD PMID:15282335 MGI:3522557 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Kdm6a lysine demethylase 6A acts_upstream_of_or_within ISO MGI:5448825 (MGI:5448135|PMID:22949634) RGD PMID:22949634 MGI:5448135 NCBI chr  X:4,805,493...4,945,788
Ensembl chr  X:4,806,277...4,945,944
JBrowse link
G Klf4 Kruppel like factor 4 involved_in ISO (MGI:5428344|PMID:22723415) RGD PMID:22723415 MGI:5428344 NCBI chr 5:72,283,311...72,287,669
Ensembl chr 5:72,283,313...72,287,669
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 involved_in IBA
ISO
IEA
PMID:21873635
MGI:1202879|MGI:1926601|MGI:98956 (MGI:1306711|PMID:9769173), (MGI:1861366|PMID:10933391), (MGI:3640895|PMID:16678815), (MGI:3722225|PMID:17699607)
(PMID:10644691), (PMID:20123964)
GO_REF:0000107
RGD
Ensembl
PMID:9769173 PMID:10644691 PMID:10933391 PMID:16678815 PMID:17699607 PMID:20123964, PMID:21873635 GO_REF:0000107 MGI:1306711 MGI:1861366 MGI:3640895 MGI:3722225, RGD:13792537 NCBI chr 2:236,232,115...236,345,061
Ensembl chr 2:236,233,239...236,345,056
JBrowse link
G Lrp5 LDL receptor related protein 5 involved_in ISO UniProtKB:O00755|UniProtKB:P02649|UniProtKB:P04426 (PMID:11029007), (PMID:11336703), (PMID:12121999), (PMID:12857724), (PMID:15908424), (PMID:16805831), (PMID:18044981), (PMID:19673927), (PMID:24706814), (PMID:25920554)
MGI:1196625|MGI:2136761|MGI:3663738|MGI:98961 (MGI:2178168|PMID:11956231), (MGI:3045675|PMID:15143170), (MGI:3581375|PMID:15923619), (MGI:3692480|PMID:16973609)
RGD PMID:11029007 PMID:11336703 PMID:11956231 PMID:12121999 PMID:12857724 PMID:15143170 PMID:15908424 PMID:15923619 PMID:16805831 PMID:16973609 PMID:18044981 PMID:19673927 PMID:24706814 PMID:25920554 MGI:2178168 MGI:3045675 MGI:3581375 MGI:3692480 NCBI chr 1:218,816,833...218,920,147
Ensembl chr 1:218,816,841...218,920,094
JBrowse link
G Lrp6 LDL receptor related protein 6 involved_in IMP
ISO
UniProtKB:O00755|UniProtKB:P02649 (PMID:11029007), (PMID:11448771), (PMID:11742004), (PMID:12121999), (PMID:14739301), (PMID:15271658), (PMID:15908424), (PMID:16805831), (PMID:17239604), (PMID:18215320), (PMID:19107203), (PMID:20059949), (PMID:20093106), (PMID:20093472), (PMID:20137080)
MGI:1329040|MGI:1922667|MGI:2156191|MGI:2673982|MGI:4415718|MGI:98956 (MGI:1891551|PMID:11029008), (MGI:3045540|PMID:15064719), (MGI:3045675|PMID:15143170), (MGI:3055483|PMID:15469977), (MGI:3603992|PMID:16126904), (MGI:3774879|PMID:18256198), (MGI:4358010|PMID:19700620), (MGI:4365357|PMID:18505367), (MGI:4413372|PMID:19795512), (MGI:4420746|PMID:19910923)
RGD PMID:11029007 PMID:11029008 PMID:11448771 PMID:11742004 PMID:12121999 PMID:14739301 PMID:15064719 PMID:15143170 PMID:15271658 PMID:15469977 PMID:15908424 PMID:16126904 PMID:16805831 PMID:17239604 PMID:18215320 PMID:18256198 PMID:18505367 PMID:19107203 PMID:19700620 PMID:19795512 PMID:19910923 PMID:20059949 PMID:20093106 PMID:20093472 PMID:20137080, PMID:18006602 MGI:1891551 MGI:3045540 MGI:3045675 MGI:3055483 MGI:3603992 MGI:3774879 MGI:4358010 MGI:4365357 MGI:4413372 MGI:4420746, RGD:4110127 NCBI chr 4:168,194,054...168,323,962
Ensembl chr 4:168,194,927...168,323,751
JBrowse link
G Med12 mediator complex subunit 12 acts_upstream_of_or_within ISO MGI:4839486 (MGI:4839483|PMID:20630950) RGD PMID:20630950 MGI:4839483 NCBI chr  X:71,174,653...71,197,812
Ensembl chr  X:71,174,699...71,197,812
JBrowse link
G Mgat3 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase acts_upstream_of_or_within ISO (MGI:5613435|PMID:24619415) RGD PMID:24619415 MGI:5613435 NCBI chr 7:121,394,541...121,436,935
Ensembl chr 7:121,408,829...121,435,022
JBrowse link
G Mir135a microRNA 135a acts_upstream_of_or_within ISO (MGI:5779436|PMID:27048518) RGD PMID:27048518 MGI:5779436 NCBI chr 7:32,894,877...32,894,976
Ensembl chr 7:32,894,877...32,894,976
JBrowse link
G Mir135b microRNA 135b acts_upstream_of_or_within ISO (MGI:5779436|PMID:27048518) RGD PMID:27048518 MGI:5779436 NCBI chr13:48,976,986...48,977,082
Ensembl chr13:48,976,986...48,977,082
JBrowse link
G Ndel1 nudE neurodevelopment protein 1-like 1 NOT|involved_in ISO (MGI:4821185|PMID:20624590) RGD PMID:20624590 MGI:4821185 NCBI chr10:55,398,919...55,456,654
Ensembl chr10:55,411,901...55,444,861
JBrowse link
G Plpp3 phospholipid phosphatase 3 involved_in IBA
ISO
IEA
PMID:21873635
(MGI:4820698|PMID:20123964)
GO_REF:0000107
RGD
Ensembl
PMID:20123964, PMID:21873635 GO_REF:0000107 MGI:4820698, RGD:13792537 NCBI chr 5:124,690,214...124,765,499
Ensembl chr 5:124,690,214...124,765,498
JBrowse link
G Porcn porcupine O-acyltransferase involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:5613435|PMID:24619415)
RGD PMID:24619415, PMID:21873635 MGI:5613435, RGD:13792537 NCBI chr  X:15,035,569...15,048,440
Ensembl chr  X:15,035,569...15,048,440
JBrowse link
G Prop1 PROP paired-like homeobox 1 acts_upstream_of_or_within ISO MGI:88276 (MGI:3690195|PMID:16678101) RGD PMID:16678101 MGI:3690195 NCBI chr10:36,449,920...36,452,381
Ensembl chr10:36,449,920...36,452,378
JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (PMID:20123964) RGD PMID:20123964 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Pygo1 pygopus family PHD finger 1 involved_in ISO MGI:1916161 (MGI:3712628|PMID:17425782) RGD PMID:17425782 MGI:3712628 NCBI chr 8:79,607,013...79,625,188
Ensembl chr 8:79,606,789...79,627,166
JBrowse link
G Pygo2 pygopus family PHD finger 2 involved_in
acts_upstream_of_or_within
ISO MGI:1919385|MGI:3711738 (MGI:3712628|PMID:17425782), (MGI:4821247|PMID:19487454)
MGI:3712856 (MGI:3712628|PMID:17425782)
RGD PMID:17425782 PMID:19487454 MGI:3712628 MGI:4821247 NCBI chr 2:188,757,167...188,762,285
Ensembl chr 2:188,757,489...188,762,282
JBrowse link
G Reck reversion-inducing-cysteine-rich protein with kazal motifs involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 5:59,348,568...59,415,169
Ensembl chr 5:59,348,639...59,415,135
JBrowse link
G Rspo1 R-spondin 1 acts_upstream_of_or_within ISO PR:Q61091 (MGI:3664518|PMID:16543246) RGD PMID:16543246 MGI:3664518 NCBI chr 5:142,986,526...143,007,847
Ensembl chr 5:142,986,526...143,007,831
JBrowse link
G Sdc1 syndecan 1 acts_upstream_of_or_within ISO MGI:1934652 (MGI:3027462|PMID:14681683) RGD PMID:14681683 MGI:3027462 NCBI chr 6:33,885,576...33,908,038
Ensembl chr 6:33,885,495...33,908,016
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in IBA
IEA
ISO
PMID:21873635
GO_REF:0000107
(PMID:18787224)
Ensembl
RGD
PMID:18787224, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr16:73,372,007...73,410,777
Ensembl chr16:73,372,007...73,410,777
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:182,723,732...182,731,277
Ensembl chr 2:182,723,854...182,731,764
JBrowse link
G Sfrp4 secreted frizzled-related protein 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:47,383,983...47,394,065
Ensembl chr17:47,297,489...47,394,328
JBrowse link
G Sfrp5 secreted frizzled-related protein 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:261,442,108...261,446,570
Ensembl chr 1:261,442,108...261,446,570
JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3703195|PMID:17284610)
Ensembl
RGD
PMID:17284610 GO_REF:0000107 MGI:3703195 NCBI chr 4:718,538...727,691
Ensembl chr 4:718,538...727,691
JBrowse link
G Stk11 serine/threonine kinase 11 acts_upstream_of_or_within ISO MGI:3579498 (MGI:3778268|PMID:18381428) RGD PMID:18381428 MGI:3778268 NCBI chr 7:12,440,751...12,457,513
Ensembl chr 7:12,440,751...12,457,513
JBrowse link
G Tcf7 transcription factor 7 involved_in IBA
ISO
PMID:21873635
(MGI:2386811|PMID:12235125)
RGD PMID:12235125, PMID:21873635 MGI:2386811, RGD:13792537 NCBI chr10:37,616,033...37,646,027
Ensembl chr10:37,617,279...37,645,802
JBrowse link
G Tcf7l1 transcription factor 7 like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:100,492,796...100,660,401
Ensembl chr 4:100,491,798...100,660,140
JBrowse link
G Tcf7l2 transcription factor 7 like 2 involved_in IBA
ISO
PMID:21873635
MGI:96770 (MGI:1196720|PMID:9488439), (MGI:3722225|PMID:17699607), (MGI:3758508|PMID:10937998)
RGD PMID:9488439 PMID:10937998 PMID:17699607, PMID:21873635 MGI:1196720 MGI:3722225 MGI:3758508, RGD:13792537 NCBI chr 1:276,686,911...276,730,517
Ensembl chr 1:276,659,542...276,730,514
Ensembl chr 1:276,659,542...276,730,514
JBrowse link
G Uty ubiquitously transcribed tetratricopeptide repeat containing, Y-linked acts_upstream_of_or_within ISO (MGI:5448135|PMID:22949634) RGD PMID:22949634 MGI:5448135 NCBI chr  Y:1,065,274...1,206,127
Ensembl chr  Y:989,240...1,206,096
JBrowse link
G Wnt1 Wnt family member 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:4835152|PMID:15265686), (MGI:5009183|PMID:12121999), (MGI:5693230|PMID:17239604), (MGI:5770063|PMID:21752258)
MGI:1329040 (MGI:1261652|PMID:9652750), (MGI:1929591|PMID:11265645), (MGI:3045540|PMID:15064719), (MGI:3045675|PMID:15143170), (MGI:3522557|PMID:15282335), (MGI:3619629|PMID:16207730), (MGI:3664518|PMID:16543246), (MGI:3758508|PMID:10937998), (MGI:4453528|PMID:20383322)
(PMID:10644691), (PMID:12154096), (PMID:19756656), (PMID:19778454), (PMID:28733458)
RGD PMID:9652750 PMID:10644691 PMID:10937998 PMID:11265645 PMID:12121999 PMID:12154096 PMID:15064719 PMID:15143170 PMID:15265686 PMID:15282335 PMID:16207730 PMID:16543246 PMID:17239604 PMID:19756656 PMID:19778454 PMID:20383322 PMID:21752258 PMID:28733458, PMID:21873635 MGI:1261652 MGI:1929591 MGI:3045540 MGI:3045675 MGI:3522557 MGI:3619629 MGI:3664518 MGI:3758508 MGI:4453528 MGI:4835152 MGI:5009183 MGI:5693230 MGI:5770063, RGD:13792537 NCBI chr 7:140,464,999...140,469,046
Ensembl chr 7:140,464,999...140,469,046
JBrowse link
G Wnt10a Wnt family member 10A involved_in ISO
IBA
(PMID:28733458)
PMID:21873635
RGD PMID:28733458, PMID:21873635 RGD:13792537 NCBI chr 9:82,053,581...82,066,047
Ensembl chr 9:82,053,581...82,066,047
JBrowse link
G Wnt10b Wnt family member 10B involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3758508|PMID:10937998)
(PMID:17761539)
RGD PMID:10937998 PMID:17761539, PMID:21873635 MGI:3758508, RGD:13792537 NCBI chr 7:140,448,284...140,466,159
Ensembl chr 7:140,448,465...140,454,268
JBrowse link
G Wnt11 Wnt family member 11 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3850932|PMID:19213727)
RGD PMID:19213727, PMID:21873635 MGI:3850932, RGD:13792537 NCBI chr 1:163,794,136...163,813,756
Ensembl chr 1:163,797,660...163,813,756
JBrowse link
G Wnt16 Wnt family member 16 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:49,369,246...49,388,156
Ensembl chr 4:49,369,296...49,379,703
JBrowse link
G Wnt2 Wnt family member 2 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1261834|MGI:4361155 (MGI:1261652|PMID:9652750), (MGI:4360856|PMID:19686689), (MGI:4439199|PMID:20159597)
(PMID:10347172), (PMID:10557084), (PMID:17948129), (PMID:20018874)
RGD PMID:9652750 PMID:10347172 PMID:10557084 PMID:17948129 PMID:19686689 PMID:20018874 PMID:20159597, PMID:21873635 MGI:1261652 MGI:4360856 MGI:4439199, RGD:13792537 NCBI chr 4:45,286,845...45,332,899
Ensembl chr 4:45,292,437...45,332,420
JBrowse link
G Wnt2b Wnt family member 2B involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:11741304), (PMID:15135146)
MGI:98954 (MGI:4360856|PMID:19686689)
PMID:21873635
RGD PMID:11741304 PMID:15135146 PMID:19686689, PMID:21873635 MGI:4360856, RGD:13792537 NCBI chr 2:207,433,771...207,457,094
Ensembl chr 2:207,440,886...207,455,258
JBrowse link
G Wnt3 Wnt family member 3 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:10557084), (PMID:15588944), (PMID:18044981), (PMID:28733458)
MGI:1329040 (MGI:3789532|PMID:18403408)
PMID:21873635
RGD PMID:10557084 PMID:15588944 PMID:18044981 PMID:18403408 PMID:28733458, PMID:21873635 MGI:3789532, RGD:13792537 NCBI chr10:91,830,709...91,874,907
Ensembl chr10:91,830,654...91,874,793
JBrowse link
G Wnt3a Wnt family member 3A involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:18941195), (PMID:19101069), (PMID:20137080), (PMID:20723538), (PMID:23797875), (PMID:26902720), (PMID:28733458)
MGI:106613|MGI:108460|MGI:108520|MGI:1298218|MGI:1857489|MGI:1888513|MGI:1924828|MGI:1933114|MGI:892032|MGI:94941|MGI:96770|UniPRotKB:Q08463 (MGI:1340921|PMID:10409711), (MGI:1861366|PMID:10933391), (MGI:1891551|PMID:11029008), (MGI:3045675|PMID:15143170), (MGI:3573812|PMID:15579909), (MGI:3575460|PMID:15796911), (MGI:3619748|PMID:16115200), (MGI:3621828|PMID:16602827), (MGI:3664518|PMID:16543246), (MGI:3707948|PMID:17244647), (MGI:3711603|PMID:17462603), (MGI:3763604|PMID:17888405), (MGI:3805609|PMID:18555765), (MGI:3814781|PMID:18606138), (MGI:3835914|PMID:19075000), (MGI:3849215|PMID:19497282), (MGI:4359544|PMID:19701191), (MGI:4367118|PMID:19896444), (MGI:4368064|PMID:19699733), (MGI:4414728|PMID:19920076), (MGI:4420746|PMID:19910923), (MGI:4421265|PMID:19961844), (MGI:4456962|PMID:10557084), (MGI:4835138|PMID:18929644), (MGI:4835152|PMID:15265686), (MGI:4836133|PMID:20371816), (MGI:5009183|PMID:12121999), (MGI:5285137|PMID:21189423), (MGI:5543552|PMID:23677472), (MGI:5700287|PMID:24080158), (MGI:5700300|PMID:19001373), (MGI:5705223|PMID:17027228), (MGI:6114891|PMID:26902720)
(MGI:6453919|PMID:31222549)
PMID:21873635
RGD PMID:10409711 PMID:10557084 PMID:10933391 PMID:11029008 PMID:12121999 PMID:15143170 PMID:15265686 PMID:15579909 PMID:15796911 PMID:16115200 PMID:16543246 PMID:16602827 PMID:17027228 PMID:17244647 PMID:17462603 PMID:17888405 PMID:18555765 PMID:18606138 PMID:18929644 PMID:18941195 PMID:19001373 PMID:19075000 PMID:19101069 PMID:19497282 PMID:19699733 PMID:19701191 PMID:19896444 PMID:19910923 PMID:19920076 PMID:19961844 PMID:20137080 PMID:20371816 PMID:20723538 PMID:21189423 PMID:23677472 PMID:23797875 PMID:24080158 PMID:26902720 PMID:28733458 PMID:31222549, PMID:21873635 MGI:1340921 MGI:1861366 MGI:1891551 MGI:3045675 MGI:3573812 MGI:3575460 MGI:3619748 MGI:3621828 MGI:3664518 MGI:3707948 MGI:3711603 MGI:3763604 MGI:3805609 MGI:3814781 MGI:3835914 MGI:3849215 MGI:4359544 MGI:4367118 MGI:4368064 MGI:4414728 MGI:4420746 MGI:4421265 MGI:4456962 MGI:4835138 MGI:4835152 MGI:4836133 MGI:5009183 MGI:5285137 MGI:5543552 MGI:5700287 MGI:5700300 MGI:5705223 MGI:6114891 MGI:6453919, RGD:13792537 NCBI chr10:45,598,898...45,643,151
Ensembl chr10:45,598,912...45,638,035
JBrowse link
G Wnt4 Wnt family member 4 involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000107
(MGI:4835152|PMID:15265686), (MGI:5571208|PMID:24681597)
MGI:88276 (MGI:1929591|PMID:11265645), (MGI:4454604|PMID:20454446)
PMID:21873635
(PMID:15317892), (PMID:16959810), (PMID:18182450)
Ensembl
RGD
PMID:11265645 PMID:15265686 PMID:15317892 PMID:16959810 PMID:18182450 PMID:20454446 PMID:24681597, PMID:21873635 GO_REF:0000107 MGI:1929591 MGI:4454604 MGI:4835152 MGI:5571208, RGD:13792537 NCBI chr 5:155,649,238...155,668,065
Ensembl chr 5:155,649,217...155,672,579
JBrowse link
G Wnt5a Wnt family member 5A involved_in
acts_upstream_of_or_within
NOT|involved_in
IBA
ISO
IEA
PMID:21873635
MGI:108520 (MGI:3621828|PMID:16602827), (MGI:3722740|PMID:17804636)
(MGI:4835138|PMID:18929644), (MGI:5571208|PMID:24681597)
(MGI:3707948|PMID:17244647)
GO_REF:0000107
RGD
Ensembl
PMID:16602827 PMID:17244647 PMID:17804636 PMID:18929644 PMID:24681597, PMID:21873635 GO_REF:0000107 MGI:3621828 MGI:3707948 MGI:3722740 MGI:4835138 MGI:5571208, RGD:13792537 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
G Wnt5b Wnt family member 5B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:151,500,962...151,516,894
Ensembl chr 4:151,500,957...151,516,894
JBrowse link
G Wnt6 Wnt family member 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:82,033,543...82,047,172
Ensembl chr 9:82,033,543...82,047,166
JBrowse link
G Wnt7a Wnt family member 7A involved_in
acts_upstream_of_or_within
IMP
ISO
IBA
(MGI:4441133|PMID:12937339)
MGI:98962 (MGI:3821408|PMID:19023080)
(PMID:12857724), (PMID:15802269), (PMID:16805831), (PMID:18986540), (PMID:28733458)
PMID:21873635
RGD PMID:12857724 PMID:12937339 PMID:15802269 PMID:16805831 PMID:18986540 PMID:19023080 PMID:28733458, PMID:18567805, PMID:21873635 MGI:3821408 MGI:4441133, RGD:4107045, RGD:13792537 NCBI chr 4:122,994,425...123,040,609
Ensembl chr 4:122,994,425...123,040,609
JBrowse link
G Wnt7b Wnt family member 7B involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:108520|MGI:1196625|MGI:1278315|MGI:2136761|MGI:3641208|MGI:3793280|MGI:98961 (MGI:3581375|PMID:15923619), (MGI:3604165|PMID:16163358), (MGI:3722740|PMID:17804636), (MGI:3821408|PMID:19023080), (MGI:3821953|PMID:19060336), (MGI:4359548|PMID:19690384)
(PMID:28733458)
RGD PMID:15923619 PMID:16163358 PMID:17804636 PMID:19023080 PMID:19060336 PMID:19690384 PMID:28733458, PMID:21873635 MGI:3581375 MGI:3604165 MGI:3722740 MGI:3821408 MGI:3821953 MGI:4359548, RGD:13792537 NCBI chr 7:126,423,418...126,465,724
Ensembl chr 7:126,420,656...126,465,723
JBrowse link
G Wnt8a Wnt family member 8A involved_in ISO
IBA
(PMID:28733458)
PMID:21873635
RGD PMID:28733458, PMID:21873635 RGD:13792537 NCBI chr18:27,331,236...27,336,829
Ensembl chr18:27,331,236...27,336,829
JBrowse link
G Wnt8b Wnt family member 8B involved_in IBA
ISO
PMID:21873635
(PMID:28733458)
RGD PMID:28733458, PMID:21873635 RGD:13792537 NCBI chr 1:264,244,150...264,266,136
Ensembl chr 1:264,260,505...264,264,302
JBrowse link
G Wnt9a Wnt family member 9A involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:88276 (MGI:3701031|PMID:16818445)
(PMID:28733458)
RGD PMID:16818445 PMID:28733458, PMID:21873635 MGI:3701031, RGD:13792537 NCBI chr10:45,659,045...45,686,103
Ensembl chr10:45,659,143...45,681,393
JBrowse link
G Wnt9b Wnt family member 9B involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:88276 (MGI:4950307|PMID:21350016)
(PMID:28733458)
RGD PMID:21350016 PMID:28733458, PMID:21873635 MGI:4950307, RGD:13792537 NCBI chr10:91,785,892...91,808,061
Ensembl chr10:91,785,893...91,807,937
JBrowse link
canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a Wnt family member 3A involved_in ISO (PMID:20559569) RGD PMID:20559569 NCBI chr10:45,598,898...45,643,151
Ensembl chr10:45,598,912...45,638,035
JBrowse link
G Wnt8a Wnt family member 8A involved_in ISO (PMID:20559569) RGD PMID:20559569 NCBI chr18:27,331,236...27,336,829
Ensembl chr18:27,331,236...27,336,829
JBrowse link
canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:2156191 (MGI:4413394|PMID:19705442) RGD PMID:19705442 MGI:4413394 NCBI chr 4:168,194,054...168,323,962
Ensembl chr 4:168,194,927...168,323,751
JBrowse link
canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin beta 1 involved_in IEA
ISO
GO_REF:0000107
MGI:2148567|MGI:3841145 (MGI:6284231|PMID:30478225)
Ensembl
RGD
PMID:30478225 GO_REF:0000107 MGI:6284231 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Fzd1 frizzled class receptor 1 involved_in ISO
IEA
(PMID:20039315)
GO_REF:0000107
RGD
Ensembl
PMID:20039315 GO_REF:0000107 NCBI chr 4:26,470,864...26,475,262
Ensembl chr 4:26,470,864...26,475,262
JBrowse link
G Wnt3 Wnt family member 3 involved_in ISO
IEA
(PMID:20039315)
GO_REF:0000107
RGD
Ensembl
PMID:20039315 GO_REF:0000107 NCBI chr10:91,830,709...91,874,907
Ensembl chr10:91,830,654...91,874,793
JBrowse link
canonical Wnt signaling pathway involved in metanephric kidney development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata3 GATA binding protein 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:3822373|PMID:19112489)
UniProt
RGD
PMID:19112489 GO_REF:0000024 MGI:3822373 NCBI chr17:72,419,752...72,452,043
Ensembl chr17:72,429,618...72,450,681
JBrowse link
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 involved_in ISO (MGI:5006869|PMID:21523854) RGD PMID:21523854 MGI:5006869 NCBI chr 3:101,051,960...101,152,119
Ensembl chr 3:101,051,955...101,152,119
JBrowse link
canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt1 Wnt family member 1 involved_in ISO (MGI:5705221|PMID:19951692) RGD PMID:19951692 MGI:5705221 NCBI chr 7:140,464,999...140,469,046
Ensembl chr 7:140,464,999...140,469,046
JBrowse link
G Wnt2 Wnt family member 2 involved_in ISO (PMID:20018874) RGD PMID:20018874 NCBI chr 4:45,286,845...45,332,899
Ensembl chr 4:45,292,437...45,332,420
JBrowse link
G Wnt3 Wnt family member 3 involved_in IEA
ISO
GO_REF:0000107
(PMID:25640183)
Ensembl
RGD
PMID:25640183 GO_REF:0000107 NCBI chr10:91,830,709...91,874,907
Ensembl chr10:91,830,654...91,874,793
JBrowse link
canonical Wnt signaling pathway involved in negative regulation of apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway acts_upstream_of_or_within ISO MGI:97250 (MGI:3710040|PMID:17377531) RGD PMID:17377531 MGI:3710040 NCBI chr18:27,011,710...27,106,323
Ensembl chr18:27,047,382...27,105,531
JBrowse link
G Mitf melanocyte inducing transcription factor acts_upstream_of_or_within ISO (MGI:2386811|PMID:12235125) RGD PMID:12235125 MGI:2386811 NCBI chr 4:130,172,484...130,425,496
Ensembl chr 4:130,172,727...130,425,532
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor acts_upstream_of_or_within ISO MGI:88039 (MGI:3710040|PMID:17377531) RGD PMID:17377531 MGI:3710040 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Tcf7 transcription factor 7 involved_in ISO (MGI:2386811|PMID:12235125) RGD PMID:12235125 MGI:2386811 NCBI chr10:37,616,033...37,646,027
Ensembl chr10:37,617,279...37,645,802
JBrowse link
canonical Wnt signaling pathway involved in osteoblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fzd1 frizzled class receptor 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:20039315)
Ensembl
RGD
PMID:20039315 GO_REF:0000107 NCBI chr 4:26,470,864...26,475,262
Ensembl chr 4:26,470,864...26,475,262
JBrowse link
G Wnt3 Wnt family member 3 involved_in IEA
ISO
GO_REF:0000107
(PMID:20039315)
Ensembl
RGD
PMID:20039315 GO_REF:0000107 NCBI chr10:91,830,709...91,874,907
Ensembl chr10:91,830,654...91,874,793
JBrowse link
canonical Wnt signaling pathway involved in positive regulation of apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway acts_upstream_of_or_within ISO MGI:97250 (MGI:3710040|PMID:17377531) RGD PMID:17377531 MGI:3710040 NCBI chr18:27,011,710...27,106,323
Ensembl chr18:27,047,382...27,105,531
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor acts_upstream_of_or_within ISO MGI:88039 (MGI:3710040|PMID:17377531) RGD PMID:17377531 MGI:3710040 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin beta 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:2446944|PMID:12464179)
Ensembl
RGD
PMID:12464179 GO_REF:0000107 MGI:2446944 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:2156191 (MGI:4413394|PMID:19705442) RGD PMID:19705442 MGI:4413394 NCBI chr 4:168,194,054...168,323,962
Ensembl chr 4:168,194,927...168,323,751
JBrowse link
canonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plpp3 phospholipid phosphatase 3 involved_in ISO (PMID:20123964) RGD PMID:20123964 NCBI chr 5:124,690,214...124,765,499
Ensembl chr 5:124,690,214...124,765,498
JBrowse link
canonical Wnt signaling pathway involved in positive regulation of endothelial cell migration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plpp3 phospholipid phosphatase 3 involved_in ISO (PMID:20123964) RGD PMID:20123964 NCBI chr 5:124,690,214...124,765,499
Ensembl chr 5:124,690,214...124,765,498
JBrowse link
canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin beta 1 involved_in ISO
IEA
ISS
(PMID:17072303)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:17072303 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Tcf7l2 transcription factor 7 like 2 involved_in ISO (PMID:17072303) RGD PMID:17072303 NCBI chr 1:276,686,911...276,730,517
Ensembl chr 1:276,659,542...276,730,514
Ensembl chr 1:276,659,542...276,730,514
JBrowse link
canonical Wnt signaling pathway involved in positive regulation of wound healing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plpp3 phospholipid phosphatase 3 involved_in ISO (PMID:20123964) RGD PMID:20123964 NCBI chr 5:124,690,214...124,765,499
Ensembl chr 5:124,690,214...124,765,498
JBrowse link
canonical Wnt signaling pathway involved in regulation of cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dvl2 dishevelled segment polarity protein 2 involved_in ISO (PMID:18787224) RGD PMID:18787224 NCBI chr10:56,609,810...56,619,269
Ensembl chr10:56,610,051...56,619,269
JBrowse link
canonical Wnt signaling pathway involved in stem cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3 Wnt family member 3 involved_in ISO
IEA
(PMID:25640183)
GO_REF:0000107
RGD
Ensembl
PMID:25640183 GO_REF:0000107 NCBI chr10:91,830,709...91,874,907
Ensembl chr10:91,830,654...91,874,793
JBrowse link
negative regulation of canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07043818.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr19:41,539,959...41,541,986 JBrowse link
G Amer1 APC membrane recruitment protein 1 involved_in ISO UniProtKB:P28026 (PMID:17510365), (PMID:21498506) RGD PMID:17510365 PMID:21498506 NCBI chr  X:64,686,620...64,702,504
Ensembl chr  X:64,686,623...64,702,441
JBrowse link
G Amer2 APC membrane recruitment protein 2 involved_in ISO (PMID:22128170) RGD PMID:22128170 NCBI chr15:40,663,183...40,667,705
Ensembl chr15:40,665,041...40,667,173
JBrowse link
G Amfr autocrine motility factor receptor involved_in ISO (PMID:31073040)
(MGI:6303730|PMID:31073040)
RGD PMID:31073040 MGI:6303730 NCBI chr19:11,473,538...11,509,500
Ensembl chr19:11,473,541...11,508,102
JBrowse link
G Ankrd6 ankyrin repeat domain 6 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
UniProtKB:P42568 (MGI:4354654|PMID:19591803)
RGD PMID:19591803, PMID:21873635 MGI:4354654, RGD:13792537 NCBI chr 5:48,052,610...48,167,568
Ensembl chr 5:48,052,401...48,194,294
JBrowse link
G Apc APC regulator of WNT signaling pathway involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000107
UniProtKB:P25054 (PMID:10656683), (PMID:21471006), (PMID:30374053)
MGI:1857966|MGI:3521822 (MGI:2156303|PMID:11756652), (MGI:3044547|PMID:15198980), (MGI:3513734|PMID:15563600)
PMID:21873635
Ensembl
RGD
PMID:10656683 PMID:11756652 PMID:15198980 PMID:15563600 PMID:21471006 PMID:30374053, PMID:21873635 GO_REF:0000107 MGI:2156303 MGI:3044547 MGI:3513734, RGD:13792537 NCBI chr18:27,011,710...27,106,323
Ensembl chr18:27,047,382...27,105,531
JBrowse link
G Apc2 APC regulator of WNT signaling pathway 2 involved_in IBA
ISO
PMID:21873635
(PMID:10021369), (PMID:26393419), (PMID:9823329)
RGD PMID:9823329 PMID:10021369 PMID:26393419, PMID:21873635 RGD:13792537 NCBI chr 7:12,258,468...12,280,459
Ensembl chr 7:12,258,468...12,275,609
JBrowse link
G Apoe apolipoprotein E involved_in ISO
IEA
UniProtKB:O00755|UniProtKB:O54908|UniProtKB:O75197|UniProtKB:O75581 (PMID:16805831)
GO_REF:0000107
RGD
Ensembl
PMID:16805831 GO_REF:0000107 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G App amyloid beta precursor protein involved_in ISO (PMID:18234671) RGD PMID:18234671 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Axin1 axin 1 acts_upstream_of_or_within
involved_in
IDA
ISO
(MGI:3573812|PMID:15579909), (MGI:3840033|PMID:19204372)
(PMID:10644691), (PMID:22899650)
RGD PMID:10644691 PMID:15579909 PMID:19204372 PMID:22899650, PMID:9482734 MGI:3573812 MGI:3840033, RGD:632259
G Axin2 axin 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:11017067), (PMID:11940574), (PMID:16247484)
Ensembl
RGD
PMID:11017067 PMID:11940574 PMID:16247484 GO_REF:0000107 NCBI chr10:97,212,483...97,238,824
Ensembl chr10:97,212,432...97,239,642
JBrowse link
G Bicc1 BicC family RNA binding protein 1 involved_in ISO (PMID:21922595) RGD PMID:21922595 NCBI chr20:18,780,605...18,940,429
Ensembl chr20:18,780,605...18,940,408
JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in ISO
IEA
(PMID:17202865)
GO_REF:0000107
RGD
Ensembl
PMID:17202865 GO_REF:0000107 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
JBrowse link
G Cav1 caveolin 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:4821088|PMID:10816572)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:10816572 GO_REF:0000024 GO_REF:0000107 MGI:4821088 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Cby1 chibby family member 1, beta catenin antagonist acts_upstream_of_or_within ISO MGI:3714454 (MGI:3840551|PMID:19364920) RGD PMID:19364920 MGI:3840551 NCBI chr 7:120,891,930...120,898,318
Ensembl chr 7:120,891,940...120,897,687
JBrowse link
G Ccdc88c coiled-coil domain containing 88C involved_in ISO (PMID:26126266) RGD PMID:26126266 NCBI chr 6:124,905,811...125,028,011
Ensembl chr 6:124,905,808...125,027,553
JBrowse link
G Cdh1 cadherin 1 acts_upstream_of_or_within ISO (MGI:5449145|PMID:22766025) RGD PMID:22766025 MGI:5449145 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdh2 cadherin 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1278315|MGI:98956 (MGI:3835914|PMID:19075000)
Ensembl
RGD
PMID:19075000 GO_REF:0000107 MGI:3835914 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
JBrowse link
G Chd8 chromodomain helicase DNA binding protein 8 involved_in IDA
ISO
PMID:11744694
(PMID:18378692)
PMID:10921920
RGD PMID:18378692, PMID:11744694, PMID:10921920 RGD:8553770, RGD:631965 NCBI chr15:28,612,932...28,672,574
Ensembl chr15:28,612,932...28,672,569
JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 involved_in IBA
IEA
IC
ISO
PMID:21873635
GO_REF:0000107
PMID:11955436
(PMID:21331045)
Ensembl
RGD
PMID:21331045, PMID:21873635, PMID:11955436 GO_REF:0000107, RGD:13792537, RGD:10449517 NCBI chr18:56,887,722...56,910,610
Ensembl chr18:56,887,354...56,918,345
JBrowse link
G Cthrc1 collagen triple helix repeat containing 1 acts_upstream_of_or_within ISO (MGI:3814781|PMID:18606138) RGD PMID:18606138 MGI:3814781 NCBI chr 7:77,966,722...77,977,004
Ensembl chr 7:77,966,722...77,977,004
JBrowse link
G Ctnnd1 catenin delta 1 involved_in ISO (PMID:20123964) RGD PMID:20123964 NCBI chr 3:72,001,904...72,053,047
Ensembl chr 3:72,002,152...72,053,049
JBrowse link
G Cyld CYLD lysine 63 deubiquitinase involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:20227366)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:20227366 GO_REF:0000024 GO_REF:0000107 NCBI chr19:19,264,984...19,323,817
Ensembl chr19:19,265,164...19,315,357
JBrowse link
G Dab2 DAB adaptor protein 2 involved_in IGI
IEA
IBA
PMID:21762377
GO_REF:0000107
PMID:21873635
Ensembl PMID:21762377, PMID:21873635 GO_REF:0000107, RGD:7243156, RGD:13792537 NCBI chr 2:55,747,353...55,768,848
Ensembl chr 2:55,747,318...55,768,270
JBrowse link
G Dab2ip DAB2 interacting protein involved_in IEA
ISO
GO_REF:0000107
(MGI:4431163|PMID:20080667)
(PMID:20080667)
Ensembl
RGD
PMID:20080667 GO_REF:0000107 MGI:4431163 NCBI chr 3:14,889,263...15,060,286
Ensembl chr 3:14,889,510...15,060,286
JBrowse link
G Dact1 dishevelled-binding antagonist of beta-catenin 1 involved_in
acts_upstream_of_or_within
ISO
IBA
UniProtKB:P04426 (PMID:18936100), (PMID:22610794)
(MGI:3838933|PMID:19073771)
PMID:21873635
RGD PMID:18936100 PMID:19073771 PMID:22610794, PMID:21873635 MGI:3838933, RGD:13792537 NCBI chr 6:93,740,440...93,751,003
Ensembl chr 6:93,740,586...93,749,809
JBrowse link
G Dact3 dishevelled-binding antagonist of beta-catenin 3 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:5515616 (MGI:5503293|PMID:23580654)
(PMID:18538736)
RGD PMID:18538736 PMID:23580654, PMID:21873635 MGI:5503293, RGD:13792537 NCBI chr 1:78,800,754...78,812,483
Ensembl chr 1:78,800,754...78,812,483
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 involved_in IEA
ISO
GO_REF:0000107
(MGI:4821075|PMID:16434966)
Ensembl
RGD
PMID:16434966 GO_REF:0000107 MGI:4821075 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:11433302), (PMID:11448771), (PMID:11742004), (PMID:12857724), (PMID:17804805), (PMID:18044981), (PMID:20039315), (PMID:20093360), (PMID:22902902)
MGI:108078|MGI:2387760|MGI:2442252|MGI:892014|MGI:98953|MGI:98955 (MGI:3045675|PMID:15143170), (MGI:3696593|PMID:17128274), (MGI:3722740|PMID:17804636), (MGI:3789532|PMID:18403408), (MGI:3793375|PMID:18257070), (MGI:4453528|PMID:20383322)
UniProtKB:O00755|UniProtKB:P02649 (MGI:3703823|PMID:17360443), (MGI:5692401|PMID:25318560), (MGI:5705223|PMID:17027228), (MGI:5825432|PMID:16805831)
RGD PMID:11433302 PMID:11448771 PMID:11742004 PMID:12857724 PMID:15143170 PMID:16805831 PMID:17027228 PMID:17128274 PMID:17360443 PMID:17804636 PMID:17804805 PMID:18044981 PMID:18257070 PMID:18403408 PMID:20039315 PMID:20093360 PMID:20383322 PMID:22902902 PMID:25318560, PMID:21873635 MGI:3045675 MGI:3696593 MGI:3703823 MGI:3722740 MGI:3789532 MGI:3793375 MGI:4453528 MGI:5692401 MGI:5705223 MGI:5825432, RGD:13792537 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607
Ensembl chr 1:248,895,738...248,898,607
JBrowse link
G Dkk2 dickkopf WNT signaling pathway inhibitor 2 involved_in IBA
ISO
PMID:21873635
(PMID:11742004), (PMID:23587485)
RGD PMID:11742004 PMID:23587485, PMID:21873635 RGD:13792537 NCBI chr 2:237,148,918...237,240,883
Ensembl chr 2:237,148,941...237,241,350
JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 involved_in IBA
ISO
PMID:21873635
(PMID:12857724)
RGD PMID:12857724, PMID:21873635 RGD:13792537 NCBI chr 1:176,940,424...176,983,076
Ensembl chr 1:176,940,693...176,983,045
JBrowse link
G Dkk4 dickkopf WNT signaling pathway inhibitor 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:74,260,551...74,264,142
Ensembl chr16:74,260,551...74,264,142
JBrowse link
G Dkkl1 dickkopf like acrosomal protein 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:101,205,426...101,210,675
Ensembl chr 1:101,205,426...101,210,675
JBrowse link
G Draxin dorsal inhibitory axon guidance protein involved_in IBA
ISO
PMID:21873635
(MGI:4410394|PMID:19857465)
RGD PMID:19857465, PMID:21873635 MGI:4410394, RGD:13792537 NCBI chr 5:164,913,085...164,943,012
Ensembl chr 5:164,913,906...164,927,869
JBrowse link
G Egr1 early growth response 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:4834991|PMID:18281035)
Ensembl
RGD
PMID:18281035 GO_REF:0000107 MGI:4834991 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Emd emerin involved_in ISO
IEA
IBA
(PMID:16858403)
GO_REF:0000107
PMID:21873635
RGD
Ensembl
PMID:16858403, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr  X:156,452,847...156,455,858
Ensembl chr  X:156,452,818...156,456,035
JBrowse link
G Fermt1 FERM domain containing kindlin 1 involved_in ISO (MGI:5571208|PMID:24681597) RGD PMID:24681597 MGI:5571208 NCBI chr 3:125,566,744...125,607,864
Ensembl chr 3:125,566,643...125,607,735
JBrowse link
G Foxo1 forkhead box O1 acts_upstream_of_or_within ISO MGI:1890081|MGI:98956 (MGI:4367118|PMID:19896444) RGD PMID:19896444 MGI:4367118 NCBI chr 2:141,451,234...141,527,016
Ensembl chr 2:141,451,234...141,527,016
JBrowse link
G Foxo3 forkhead box O3 acts_upstream_of_or_within ISO MGI:1890077|MGI:98956 (MGI:4367118|PMID:19896444) RGD PMID:19896444 MGI:4367118 NCBI chr20:46,428,078...46,519,156
Ensembl chr20:46,428,124...46,519,144
JBrowse link
G Frmd8 FERM domain containing 8 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:221,213,312...221,233,967
Ensembl chr 1:221,213,312...221,233,962
JBrowse link
G Frzb frizzled-related protein involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:17471511)
MGI:98956 (MGI:4421265|PMID:19961844)
PMID:21873635
RGD PMID:17471511 PMID:19961844, PMID:21873635 MGI:4421265, RGD:13792537 NCBI chr 3:67,635,604...67,668,772
Ensembl chr 3:67,635,607...67,668,772
JBrowse link
G Fuz fuzzy planar cell polarity protein involved_in ISS
ISO
GO_REF:0000024
(MGI:5296432|PMID:21935430)
UniProt
RGD
PMID:21935430 GO_REF:0000024 MGI:5296432 NCBI chr 1:100,891,832...100,896,811
Ensembl chr 1:100,891,866...100,896,807
JBrowse link
G Fzd1 frizzled class receptor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3033512|PMID:14627707)
Ensembl
RGD
PMID:14627707 GO_REF:0000107 MGI:3033512 NCBI chr 4:26,470,864...26,475,262
Ensembl chr 4:26,470,864...26,475,262
JBrowse link
G Fzd4 frizzled class receptor 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:153,589,471...153,598,376
Ensembl chr 1:153,589,471...153,598,375
JBrowse link
G Fzd6 frizzled class receptor 6 involved_in ISO (PMID:14747478) RGD PMID:14747478 NCBI chr 7:77,898,329...77,931,034
Ensembl chr 7:77,899,322...77,931,029
JBrowse link
G G3bp1 G3BP stress granule assembly factor 1 acts_upstream_of_or_within ISO (MGI:5317392|PMID:21652632) RGD PMID:21652632 MGI:5317392 NCBI chr10:40,812,858...40,846,252
Ensembl chr10:40,812,858...40,846,252
JBrowse link
G Gli1 GLI family zinc finger 1 involved_in ISO (PMID:17035233) RGD PMID:17035233 NCBI chr 7:70,620,794...70,633,171
Ensembl chr 7:70,620,766...70,630,338
JBrowse link
G Gli3 GLI family zinc finger 3 involved_in ISO (PMID:17331723) RGD PMID:17331723 NCBI chr17:52,294,942...52,569,036
Ensembl chr17:52,294,942...52,569,036
JBrowse link
G Gpc3 glypican 3 involved_in
acts_upstream_of_or_within
IEA
ISO
IDA
GO_REF:0000107
MGI:2159356 (MGI:3529623|PMID:15537637)
Ensembl
RGD
PMID:15537637, PMID:15537637 GO_REF:0000107 MGI:3529623, RGD:8554067 NCBI chr  X:139,579,268...139,947,093
Ensembl chr  X:139,579,268...139,916,883
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:15539560) RGD PMID:15539560 NCBI chr 3:105,203,309...105,214,989
Ensembl chr 3:105,203,309...105,214,989
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:82,097,244...82,108,238
Ensembl chr 1:82,097,247...82,108,203
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in IBA
ISO
PMID:21873635
(MGI:4821081|PMID:12154096)
RGD PMID:12154096, PMID:21873635 MGI:4821081, RGD:13792537 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Hdac1 histone deacetylase 1 involved_in
acts_upstream_of_or_within
ISO UniProtKB:P04426|UniProtKB:Q9NYF0 (PMID:18936100)
MGI:1097691 (MGI:4359141|PMID:19503085)
RGD PMID:18936100 PMID:19503085 MGI:4359141 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Hdac2 histone deacetylase 2 acts_upstream_of_or_within ISO MGI:108086 (MGI:4359141|PMID:19503085) RGD PMID:19503085 MGI:4359141 NCBI chr20:43,084,870...43,108,198
Ensembl chr20:43,084,870...43,108,198
JBrowse link
G Invs inversin involved_in ISO (PMID:18371931) RGD PMID:18371931 NCBI chr 5:64,031,131...64,180,830
Ensembl chr 5:64,053,946...64,178,759
JBrowse link
G Isl1 ISL LIM homeobox 1 acts_upstream_of_or_within ISO MGI:88276 (MGI:4438134|PMID:19620969) RGD PMID:19620969 MGI:4438134 NCBI chr 2:48,488,911...48,501,217
Ensembl chr 2:48,487,736...48,501,436
JBrowse link
G Jade1 jade family PHD finger 1 involved_in ISO (PMID:22654112) RGD PMID:22654112 NCBI chr 2:128,461,147...128,514,298
Ensembl chr 2:128,461,224...128,514,291
JBrowse link
G Kremen1 kringle containing transmembrane protein 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:5883198|PMID:26206087)
Ensembl
RGD
PMID:26206087 GO_REF:0000107 MGI:5883198 NCBI chr14:85,441,209...85,503,661
Ensembl chr14:85,438,707...85,484,275
JBrowse link
G Lats1 large tumor suppressor kinase 1 involved_in ISO (PMID:20412773) RGD PMID:20412773 NCBI chr 1:1,784,078...1,817,310
Ensembl chr 1:1,784,078...1,817,310
JBrowse link
G Lats2 large tumor suppressor kinase 2 involved_in
acts_upstream_of_or_within
ISO (PMID:20412773)
MGI:88276 (MGI:4948149|PMID:21512031)
RGD PMID:20412773 PMID:21512031 MGI:4948149 NCBI chr15:37,943,609...37,995,175
Ensembl chr15:37,943,609...37,983,882
JBrowse link
G Limd1 LIM domain containing 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3807091|PMID:18657804)
UniProt
RGD
PMID:18657804 GO_REF:0000024 MGI:3807091 NCBI chr 8:132,553,218...132,598,826
Ensembl chr 8:132,553,218...132,598,812
JBrowse link
G Lmbr1l limb development membrane protein 1-like involved_in ISO (MGI:6303730|PMID:31073040) RGD PMID:31073040 MGI:6303730 NCBI chr 7:140,585,512...140,600,797
Ensembl chr 7:140,585,832...140,600,818
JBrowse link
G Lrp4 LDL receptor related protein 4 involved_in
acts_upstream_of_or_within
ISO (PMID:20093106), (PMID:20381006), (PMID:21471202)
MGI:1329040 (MGI:4453528|PMID:20383322)
RGD PMID:20093106 PMID:20381006 PMID:20383322 PMID:21471202 MGI:4453528 NCBI chr 3:80,362,643...80,416,684
Ensembl chr 3:80,362,858...80,416,679
JBrowse link
G Lzts2 leucine zipper tumor suppressor 2 involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000107
MGI:1270862 (MGI:5486402|PMID:23275340)
PMID:21873635
Ensembl
RGD
PMID:23275340, PMID:21873635 GO_REF:0000107 MGI:5486402, RGD:13792537 NCBI chr 1:264,765,256...264,776,553
Ensembl chr 1:264,768,105...264,776,616
JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 involved_in ISO (PMID:19443654) RGD PMID:19443654 NCBI chr 5:164,943,183...164,956,255
Ensembl chr 5:164,950,917...164,956,255
JBrowse link
G Mapk14 mitogen activated protein kinase 14 involved_in IEA
ISO
GO_REF:0000107
(MGI:5487758|PMID:17202865)
Ensembl
RGD
PMID:17202865 GO_REF:0000107 MGI:5487758 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mcc MCC regulator of WNT signaling pathway involved_in ISO (PMID:18591935), (PMID:24824780) RGD PMID:18591935 PMID:24824780 NCBI chr18:35,683,185...35,817,117
NCBI chr 1:12,006,663...12,128,849
Ensembl chr 1:12,006,660...12,128,845
Ensembl chr18:12,006,660...12,128,845
JBrowse link
G Mdk midkine involved_in ISS
ISO
GO_REF:0000024
(MGI:5008226|PMID:21185956)
UniProt
RGD
PMID:21185956 GO_REF:0000024 MGI:5008226 NCBI chr 3:80,841,003...80,843,895
Ensembl chr 3:80,841,005...80,842,916
JBrowse link
G Nkd1 NKD inhibitor of WNT signaling pathway 1 involved_in ISO (PMID:15687260)
(MGI:1934955|PMID:11356022), (MGI:5437442|PMID:11274398)
RGD PMID:11274398 PMID:11356022 PMID:15687260 MGI:1934955 MGI:5437442 NCBI chr19:19,434,720...19,509,087
Ensembl chr19:19,436,333...19,509,087
JBrowse link
G Nkd2 NKD inhibitor of WNT signaling pathway 2 involved_in ISO (PMID:15687260), (PMID:20177058) RGD PMID:15687260 PMID:20177058 NCBI chr 1:32,054,390...32,085,416
Ensembl chr 1:32,058,044...32,084,877
JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in IEA
ISO
GO_REF:0000107
(MGI:3848291|PMID:19479054)
Ensembl
RGD
PMID:19479054 GO_REF:0000107 MGI:3848291 NCBI chr10:16,635,989...16,638,758
Ensembl chr10:16,635,989...16,638,764
JBrowse link
G Nog noggin involved_in IEA
ISO
GO_REF:0000107
(PMID:15539560)
Ensembl
RGD
PMID:15539560 GO_REF:0000107 NCBI chr10:76,811,759...76,813,386
Ensembl chr10:76,811,759...76,813,386
JBrowse link
G Notch1 notch receptor 1 acts_upstream_of_or_within ISO MGI:3044585 (MGI:4438134|PMID:19620969), (MGI:5617067|PMID:25535395) RGD PMID:19620969 PMID:25535395 MGI:4438134 MGI:5617067 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Notum NOTUM, palmitoleoyl-protein carboxylesterase involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:6303810|PMID:30622831)
RGD PMID:30622831, PMID:21873635 MGI:6303810, RGD:13792537 NCBI chr10:109,832,977...109,840,661
Ensembl chr10:109,832,981...109,840,047
JBrowse link
G Nphp3 nephrocystin 3 involved_in ISO (PMID:18371931) RGD PMID:18371931 NCBI chr 8:112,526,553...112,575,745
Ensembl chr 8:112,526,553...112,575,745
JBrowse link
G Nphp4 nephrocystin 4 involved_in ISO
IBA
(PMID:22654112)
PMID:21873635
RGD PMID:22654112, PMID:21873635 RGD:13792537 NCBI chr 5:169,647,581...169,744,662
Ensembl chr 5:169,659,188...169,744,660
JBrowse link
G Nppa natriuretic peptide A involved_in ISO (PMID:23749889) RGD PMID:23749889 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Pfdn5 prefoldin subunit 5 involved_in ISO (PMID:18281035) RGD PMID:18281035 NCBI chr 7:143,924,662...143,929,400
Ensembl chr 7:143,924,662...143,929,397
JBrowse link
G Ppp2r3a protein phosphatase 2, regulatory subunit B'', alpha involved_in ISO UniProtKB:F6T226 (PMID:15687260) RGD PMID:15687260 NCBI chr 8:109,481,352...109,621,462
Ensembl chr 8:109,482,614...109,621,408
JBrowse link
G Prickle1 prickle planar cell polarity protein 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:17030191)
Ensembl
RGD
PMID:17030191 GO_REF:0000107 NCBI chr 7:134,702,964...134,799,437
Ensembl chr 7:134,702,964...134,722,215
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO (PMID:19591802) RGD PMID:19591802 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Ptpro protein tyrosine phosphatase, receptor type, O involved_in IBA
ISO
ISS
PMID:21873635
(MGI:4833733|PMID:20804755)
GO_REF:0000024
RGD
UniProt
PMID:20804755, PMID:21873635 GO_REF:0000024 MGI:4833733, RGD:13792537 NCBI chr 4:171,250,766...171,461,571
Ensembl chr 4:171,250,818...171,461,677
JBrowse link
G Ptpru protein tyrosine phosphatase, receptor type, U involved_in ISO (PMID:16574648) RGD PMID:16574648 NCBI chr 5:149,922,374...149,996,352
Ensembl chr 5:149,922,352...149,996,334
JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO MGI:95516 (MGI:3701731|PMID:16858399) RGD PMID:16858399 MGI:3701731 NCBI chr 3:8,189,594...8,307,077
Ensembl chr 3:8,192,575...8,304,976
JBrowse link
G Rbms3 RNA binding motif, single stranded interacting protein 3 involved_in ISO (PMID:28409548) RGD PMID:28409548 NCBI chr 8:124,833,804...125,645,895
Ensembl chr 8:124,661,839...125,645,898
JBrowse link
G Ror2 receptor tyrosine kinase-like orphan receptor 2 acts_upstream_of_or_within ISO MGI:98958 (MGI:3621828|PMID:16602827) RGD PMID:16602827 MGI:3621828 NCBI chr17:11,953,552...12,134,386
Ensembl chr17:11,953,552...12,134,386
JBrowse link
G Ruvbl2 RuvB-like AAA ATPase 2 involved_in ISO (PMID:11080158) RGD PMID:11080158 NCBI chr 1:101,413,766...101,426,970
Ensembl chr 1:101,413,766...101,426,852
JBrowse link
G Scyl2 SCY1 like pseudokinase 2 involved_in ISO (PMID:19643732) RGD PMID:19643732 NCBI chr 7:30,291,087...30,344,464
Ensembl chr 7:30,291,087...30,344,445
JBrowse link
G Sdhaf2 succinate dehydrogenase complex assembly factor 2 acts_upstream_of_or_within ISO (MGI:5529200|PMID:23983127) RGD PMID:23983127 MGI:5529200 NCBI chr 1:226,543,671...226,572,414
Ensembl chr 1:226,547,531...226,572,349
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in
acts_upstream_of_or_within
ISO
IDA
IBA
UniProtKB:P27467 (PMID:10347172), (PMID:16149051), (PMID:16288033), (PMID:16532032), (PMID:17035233), (PMID:17443492), (PMID:17462603), (PMID:17471511), (PMID:19072540), (PMID:19095296), (PMID:19254787), (PMID:19277043), (PMID:19569235), (PMID:24080158), (PMID:9391078), (PMID:9724099)
(MGI:4835405|PMID:16149051)
MGI:108078|MGI:1329040|MGI:98956 (MGI:3711603|PMID:17462603), (MGI:3793375|PMID:18257070), (MGI:4367118|PMID:19896444), (MGI:4429763|PMID:19850029)
PMID:21873635
RGD PMID:9391078 PMID:9724099 PMID:10347172 PMID:16149051 PMID:16288033 PMID:16532032 PMID:17035233 PMID:17443492 PMID:17462603 PMID:17471511 PMID:18257070 PMID:19072540 PMID:19095296 PMID:19254787 PMID:19277043 PMID:19569235 PMID:19850029 PMID:19896444 PMID:24080158, PMID:16149051, PMID:21873635 MGI:3711603 MGI:3793375 MGI:4367118 MGI:4429763 MGI:4835405, RGD:4107087, RGD:13792537 NCBI chr16:73,372,007...73,410,777
Ensembl chr16:73,372,007...73,410,777
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 involved_in
acts_upstream_of_or_within
IBA
ISO
IGI
PMID:21873635
MGI:1329040|MGI:892014|MGI:98956 (MGI:3711603|PMID:17462603), (MGI:3722740|PMID:17804636), (MGI:3793375|PMID:18257070), (MGI:4367118|PMID:19896444), (MGI:4429763|PMID:19850029)
PMID:24080158
(PMID:17471511)
RGD PMID:17462603 PMID:17471511 PMID:17804636 PMID:18257070 PMID:19850029 PMID:19896444, PMID:21873635, PMID:24080158 MGI:3711603 MGI:3722740 MGI:3793375 MGI:4367118 MGI:4429763, RGD:13792537, RGD:10448946 NCBI chr 2:182,723,732...182,731,277
Ensembl chr 2:182,723,854...182,731,764
JBrowse link
G Sfrp4 secreted frizzled-related protein 4 involved_in IDA
ISO
IBA
IEA
(MGI:5790095|PMID:27355534)
PMID:21873635
GO_REF:0000107
(PMID:14760084), (PMID:15705870), (PMID:18945944)
PMID:12952927
RGD
Ensembl
PMID:14760084 PMID:15705870 PMID:18945944 PMID:27355534, PMID:18567805, PMID:21873635, PMID:12952927 GO_REF:0000107 MGI:5790095, RGD:4107045, RGD:13792537, RGD:8554482 NCBI chr17:47,383,983...47,394,065
Ensembl chr17:47,297,489...47,394,328
JBrowse link
G Sfrp5 secreted frizzled-related protein 5 involved_in ISO
IBA
(PMID:19957335)
PMID:21873635
RGD PMID:19957335, PMID:21873635 RGD:13792537 NCBI chr 1:261,442,108...261,446,570
Ensembl chr 1:261,442,108...261,446,570
JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3703195|PMID:17284610)
Ensembl
RGD
PMID:17284610 GO_REF:0000107 MGI:3703195 NCBI chr 4:718,538...727,691
Ensembl chr 4:718,538...727,691
JBrowse link
G Shisa3 shisa family member 3 acts_upstream_of_or_within ISO (MGI:6453919|PMID:31222549) RGD PMID:31222549 MGI:6453919 NCBI chr14:42,216,653...42,221,225
Ensembl chr14:42,216,654...42,221,225
JBrowse link
G Shisa6 shisa family member 6 involved_in ISO (MGI:6119909|PMID:28196692) RGD PMID:28196692 MGI:6119909 NCBI chr10:52,744,069...53,037,853
Ensembl chr10:52,749,846...53,037,816
JBrowse link
G Slc9a3r1 SLC9A3 regulator 1 involved_in ISO (PMID:24862762) RGD PMID:24862762 NCBI chr10:103,713,045...103,730,145
Ensembl chr10:103,713,045...103,730,145
JBrowse link
G Snai2 snail family transcriptional repressor 2 involved_in ISO (PMID:19502595), (PMID:19756381) RGD PMID:19502595 PMID:19756381 NCBI chr11:90,404,421...90,406,730
Ensembl chr11:90,403,333...90,406,797
JBrowse link
G Sost sclerostin involved_in
acts_upstream_of_or_within
ISO (PMID:15908424)
MGI:1298218|MGI:98956 (MGI:4367118|PMID:19896444), (MGI:4458999|PMID:20359476)
RGD PMID:15908424 PMID:19896444 PMID:20359476 MGI:4367118 MGI:4458999 NCBI chr10:89,897,087...89,900,131
Ensembl chr10:89,897,087...89,900,131
JBrowse link
G Sostdc1 sclerostin domain containing 1 acts_upstream_of_or_within ISO MGI:3604658 (MGI:5319554|PMID:22509524) RGD PMID:22509524 MGI:5319554 NCBI chr 6:55,812,820...55,816,994
Ensembl chr 6:55,812,747...55,817,066
JBrowse link
G Sox10 SRY-box transcription factor 10 involved_in ISO (MGI:3768575|PMID:17875931) RGD PMID:17875931 MGI:3768575 NCBI chr 7:120,393,238...120,403,523
Ensembl chr 7:120,393,254...120,403,523
JBrowse link
G Sox13 SRY-box transcription factor 13 involved_in ISO (PMID:20028982) RGD PMID:20028982 NCBI chr13:50,434,702...50,479,118
Ensembl chr13:50,434,702...50,479,657
JBrowse link
G Sox17 SRY-box transcription factor 17 involved_in ISO (PMID:18413743), (PMID:20960469)
(MGI:3768575|PMID:17875931)
RGD PMID:17875931 PMID:18413743 PMID:20960469 MGI:3768575 NCBI chr 5:14,890,318...14,895,907
Ensembl chr 5:14,890,408...14,895,907
JBrowse link
G Sox2 SRY-box transcription factor 2 involved_in ISO (PMID:18285410)
(MGI:3768575|PMID:17875931)
RGD PMID:17875931 PMID:18285410 MGI:3768575 NCBI chr 2:121,165,137...121,167,545
Ensembl chr 2:121,165,137...121,167,545
JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(MGI:3044231|PMID:15132997), (MGI:3768575|PMID:17875931)
(MGI:3830946|PMID:17698607), (MGI:3839710|PMID:19047045)
UniProt
RGD
PMID:15132997 PMID:17698607 PMID:17875931 PMID:19047045 GO_REF:0000024 MGI:3044231 MGI:3768575 MGI:3830946 MGI:3839710 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379
JBrowse link
G Stk11 serine/threonine kinase 11 involved_in ISO
ISS
(PMID:15731909) RGD PMID:15731909, PMID:15731909 RGD:13702324 NCBI chr 7:12,440,751...12,457,513
Ensembl chr 7:12,440,751...12,457,513
JBrowse link
G Stk3 serine/threonine kinase 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1929004 (MGI:4420852|PMID:20080598)
(PMID:20412773)
Ensembl
RGD
PMID:20080598 PMID:20412773 GO_REF:0000107 MGI:4420852 NCBI chr 7:73,617,926...73,883,896
Ensembl chr 7:73,618,644...73,883,812
JBrowse link
G Stk4 serine/threonine kinase 4 involved_in
acts_upstream_of_or_within
ISO (PMID:20412773)
MGI:1928487 (MGI:4420852|PMID:20080598)
RGD PMID:20080598 PMID:20412773 MGI:4420852 NCBI chr 3:160,467,552...160,546,540
Ensembl chr 3:160,467,552...160,546,540
JBrowse link
G Tcf7l2 transcription factor 7 like 2 involved_in ISO (PMID:16532032) RGD PMID:16532032 NCBI chr 1:276,686,911...276,730,517
Ensembl chr 1:276,659,542...276,730,514
Ensembl chr 1:276,659,542...276,730,514
JBrowse link
G Tle1 TLE family member 1, transcriptional corepressor involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:88,546,607...88,630,277
Ensembl chr 5:88,546,568...88,629,491
JBrowse link
G Tle2 TLE family member 2, transcriptional corepressor involved_in IBA
ISO
PMID:21873635
(PMID:19460168)
RGD PMID:19460168, PMID:21873635 RGD:13792537 NCBI chr 7:10,988,536...11,003,957
Ensembl chr 7:10,988,532...11,003,785
JBrowse link
G Tle3 TLE family member 3, transcriptional corepressor involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:66,296,509...66,342,186
Ensembl chr 8:66,296,883...66,342,176
JBrowse link
G Tle4 TLE family member 4, transcriptional corepressor involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:231,394,606...231,531,396
Ensembl chr 1:231,393,379...231,530,786
JBrowse link
G Tle5 TLE family member 5, transcriptional modulator involved_in ISO
IEA
IBA
(PMID:19460168)
GO_REF:0000107
PMID:21873635
RGD
Ensembl
PMID:19460168, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 7:11,012,843...11,018,156
Ensembl chr 7:11,013,681...11,018,160
JBrowse link
G Tle6 TLE family member 6, subcortical maternal complex member involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:10,964,136...10,988,127
Ensembl chr 7:10,962,330...10,988,137
JBrowse link
G Tmem131l transmembrane 131 like involved_in IBA
ISO
PMID:21873635
(PMID:23690469)
RGD PMID:23690469, PMID:21873635 RGD:13792537 NCBI chr 2:182,897,332...183,031,273
Ensembl chr 2:182,897,830...183,031,214
JBrowse link
G Tmem170b transmembrane protein 170B involved_in ISO
ISS
(PMID:29367600)
GO_REF:0000024
RGD
UniProt
PMID:29367600 GO_REF:0000024 NCBI chr17:22,832,641...22,863,966
Ensembl chr17:22,832,641...22,863,966
JBrowse link
G Tmem64 transmembrane protein 64 involved_in ISO (MGI:5643786|PMID:25979161) RGD PMID:25979161 MGI:5643786 NCBI chr 5:28,850,864...28,898,203
Ensembl chr 5:28,850,950...28,867,227
JBrowse link
G Tmem88 transmembrane protein 88 involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:21044957), (PMID:26359454)
ParkinsonsUK-UCL
RGD
PMID:21044957 PMID:26359454, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr10:55,998,530...56,000,225
Ensembl chr10:55,998,530...56,000,225
JBrowse link
G Tpbg trophoblast glycoprotein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:93,491,761...93,495,132
Ensembl chr 8:93,491,761...93,495,130
JBrowse link
G Tpbgl trophoblast glycoprotein-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:164,588,032...164,591,872
Ensembl chr 1:164,589,408...164,590,562
JBrowse link
G Ubac2 UBA domain containing 2 involved_in ISO (PMID:31073040)
(MGI:6303730|PMID:31073040)
RGD PMID:31073040 MGI:6303730 NCBI chr15:108,286,407...108,433,531
Ensembl chr15:108,286,453...108,433,529
JBrowse link
G Wnt11 Wnt family member 11 involved_in
acts_upstream_of_or_within
ISO (PMID:20103596)
(MGI:3772496|PMID:18155657)
RGD PMID:18155657 PMID:20103596 MGI:3772496 NCBI chr 1:163,794,136...163,813,756
Ensembl chr 1:163,797,660...163,813,756
JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within
involved_in
NOT|involved_in
ISO MGI:1347521|MGI:1888513|MGI:98956 (MGI:2674191|PMID:12952940), (MGI:3621828|PMID:16602827), (MGI:3771517|PMID:18070933), (MGI:4420746|PMID:19910923)
UniProtKB:P27467 (MGI:3707948|PMID:17244647), (MGI:4820709|PMID:18986540), (MGI:5619434|PMID:23569434)
(MGI:5700308|PMID:15748172)
RGD PMID:12952940 PMID:15748172 PMID:16602827 PMID:17244647 PMID:18070933 PMID:18986540 PMID:19910923 PMID:23569434 MGI:2674191 MGI:3621828 MGI:3707948 MGI:3771517 MGI:4420746 MGI:4820709 MGI:5619434 MGI:5700308 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
G Wnt5b Wnt family member 5B acts_upstream_of_or_within ISO MGI:98956 (MGI:3575460|PMID:15796911) RGD PMID:15796911 MGI:3575460 NCBI chr 4:151,500,962...151,516,894
Ensembl chr 4:151,500,957...151,516,894
JBrowse link
G Wwtr1 WW domain containing transcription regulator 1 involved_in ISO (PMID:20412773) RGD PMID:20412773 NCBI chr 2:147,577,149...147,693,033
Ensembl chr 2:147,577,089...147,693,082
JBrowse link
G Znrf3 zinc and ring finger 3 involved_in ISO (PMID:22575959) RGD PMID:22575959 NCBI chr14:85,527,099...85,586,294 JBrowse link
negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (PMID:20559569) RGD PMID:20559569 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607
Ensembl chr 1:248,895,738...248,898,607
JBrowse link
negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sfrp1 secreted frizzled-related protein 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:17994217)
Ensembl
RGD
PMID:17994217 GO_REF:0000107 NCBI chr16:73,372,007...73,410,777
Ensembl chr16:73,372,007...73,410,777
JBrowse link
negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tbx18 T-box transcription factor 18 involved_in ISO (MGI:3722519|PMID:17584735) RGD PMID:17584735 MGI:3722519 NCBI chr 8:95,359,354...95,387,363
Ensembl chr 8:95,359,354...95,387,363
JBrowse link
negative regulation of canonical Wnt signaling pathway involved in osteoblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnn tenascin N involved_in ISO (MGI:3710297|PMID:17395156) RGD PMID:17395156 MGI:3710297 NCBI chr13:77,829,384...77,896,831
Ensembl chr13:77,829,382...77,896,697
JBrowse link
negative regulation of heart induction by canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a Wnt family member 3A involved_in ISO (PMID:19736317) RGD PMID:19736317 NCBI chr10:45,598,898...45,643,151
Ensembl chr10:45,598,912...45,638,035
JBrowse link
positive regulation of canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgra2 adhesion G protein-coupled receptor A2 involved_in ISO
IBA
(PMID:30026314)
(MGI:6114565|PMID:28803732)
PMID:21873635
RGD PMID:28803732 PMID:30026314, PMID:21873635 MGI:6114565, RGD:13792537 NCBI chr16:69,094,587...69,133,015
Ensembl chr16:69,095,936...69,132,584
JBrowse link
G Amer1 APC membrane recruitment protein 1 involved_in ISO (PMID:21304492) RGD PMID:21304492 NCBI chr  X:64,686,620...64,702,504
Ensembl chr  X:64,686,623...64,702,441
JBrowse link
G Ankrd39 ankyrin repeat domain 39 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:43,119,532...43,127,923
Ensembl chr 9:43,117,914...43,127,887
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like involved_in ISS
ISO
GO_REF:0000024
(MGI:5437152|PMID:22611086), (MGI:5553223|PMID:23525013)
UniProt
RGD
PMID:22611086 PMID:23525013 GO_REF:0000024 MGI:5437152 MGI:5553223 NCBI chr 1:178,039,002...178,137,469
Ensembl chr 1:178,039,063...178,137,465
JBrowse link
G Aspm assembly factor for spindle microtubules acts_upstream_of_or_within ISO MGI:88276 (MGI:5294271|PMID:21937711) RGD PMID:21937711 MGI:5294271 NCBI chr13:56,546,021...56,591,793
Ensembl chr13:56,546,021...56,591,793
JBrowse link
G Atp6ap2 ATPase H+ transporting accessory protein 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:30374053)
UniProt
RGD
PMID:30374053 GO_REF:0000024 NCBI chr  X:11,137,889...11,164,854
Ensembl chr  X:11,136,939...11,164,915
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor involved_in ISO (PMID:18838381) RGD PMID:18838381 NCBI chr17:56,905,419...56,909,675
Ensembl chr17:56,905,112...56,909,992
JBrowse link
G Caprin2 caprin family member 2 involved_in ISO (PMID:18762581) RGD PMID:18762581 NCBI chr 4:183,304,993...183,374,195
Ensembl chr 4:183,305,813...183,374,195
JBrowse link
G Cav1 caveolin 1 involved_in ISO
IEA
(PMID:16890161)
GO_REF:0000107
RGD
Ensembl
PMID:16890161 GO_REF:0000107 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Ccar2 cell cycle and apoptosis regulator 2 involved_in ISO (PMID:24824780) RGD PMID:24824780 NCBI chr15:51,818,887...51,834,443
Ensembl chr15:51,818,897...51,834,030
JBrowse link
G Cdh3 cadherin 3 involved_in ISO (PMID:23334344) RGD PMID:23334344 NCBI chr19:38,668,957...38,719,801
Ensembl chr19:38,669,230...38,719,677
JBrowse link
G Col1a1 collagen type I alpha 1 chain involved_in ISO (PMID:20018240) RGD PMID:20018240 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Csnk1d casein kinase 1, delta involved_in ISO
IBA
(PMID:20412773)
PMID:21873635
RGD PMID:20412773, PMID:21873635 RGD:13792537 NCBI chr10:110,147,786...110,182,413
Ensembl chr10:110,148,600...110,182,408
JBrowse link
G Csnk1e casein kinase 1, epsilon involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:106613|MGI:94941 (MGI:3029636|PMID:14966280), (MGI:3721039|PMID:17606995)
RGD PMID:14966280 PMID:17606995, PMID:21873635 MGI:3029636 MGI:3721039, RGD:13792537 NCBI chr 7:120,651,976...120,675,559
Ensembl chr 7:120,651,881...120,672,359
JBrowse link
G Csnk1g1 casein kinase 1, gamma 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:71,533,372...71,688,483
Ensembl chr 8:71,547,468...71,679,666
JBrowse link
G Csnk1g2 casein kinase 1, gamma 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:11,944,957...11,963,268
Ensembl chr 7:11,944,958...11,963,268
JBrowse link
G Csnk1g3 casein kinase 1, gamma 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:48,831,209...48,913,341
Ensembl chr18:48,853,418...48,911,122
JBrowse link
G Ctdnep1 CTD nuclear envelope phosphatase 1 acts_upstream_of_or_within ISO MGI:5510826 (MGI:5505383|PMID:23469192) RGD PMID:23469192 MGI:5505383 NCBI chr10:56,590,822...56,600,235
Ensembl chr10:56,591,292...56,600,232
JBrowse link
G Daam2 dishevelled associated activator of morphogenesis 2 involved_in IBA
ISO
PMID:21873635
(MGI:6114828|PMID:22227309)
RGD PMID:22227309, PMID:21873635 MGI:6114828, RGD:13792537 NCBI chr 9:13,444,883...13,493,154
Ensembl chr 9:13,446,896...13,490,669
JBrowse link
G Dact1 dishevelled-binding antagonist of beta-catenin 1 involved_in ISO (PMID:15580286) RGD PMID:15580286 NCBI chr 6:93,740,440...93,751,003
Ensembl chr 6:93,740,586...93,749,809
JBrowse link
G Dapk3 death-associated protein kinase 3 involved_in ISO (PMID:21454679) RGD PMID:21454679 NCBI chr 7:11,392,436...11,400,855
Ensembl chr 7:11,392,437...11,400,805
JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:23413191) RGD PMID:23413191 NCBI chr  X:10,400,363...10,414,010
Ensembl chr  X:10,400,366...10,413,995
JBrowse link
G Disc1 DISC1 scaffold protein acts_upstream_of_or_within ISO (MGI:5002731|PMID:21471969) RGD PMID:21471969 MGI:5002731 NCBI chr19:57,818,838...58,069,992
Ensembl chr19:57,820,260...58,066,152
JBrowse link
G Dkk2 dickkopf WNT signaling pathway inhibitor 2 involved_in ISO (PMID:12857724) RGD PMID:12857724 NCBI chr 2:237,148,918...237,240,883
Ensembl chr 2:237,148,941...237,241,350
JBrowse link
G Dlx5 distal-less homeobox 5 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2180475 (MGI:3722740|PMID:17804636)
Ensembl
RGD
PMID:17804636 GO_REF:0000107 MGI:3722740 NCBI chr 4:32,387,741...32,392,085
Ensembl chr 4:32,387,741...32,392,007
JBrowse link
G Eda ectodysplasin-A acts_upstream_of_or_within ISO MGI:1856197 (MGI:4355652|PMID:19619491) RGD PMID:19619491 MGI:4355652 NCBI chr  X:69,730,123...70,222,693
Ensembl chr  X:69,730,242...70,220,329
JBrowse link
G Egf epidermal growth factor involved_in ISO (PMID:20302655) RGD PMID:20302655 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egfr epidermal growth factor receptor involved_in ISO (PMID:20302655) RGD PMID:20302655 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Fam53b family with sequence similarity 53, member B involved_in ISO
IBA
(PMID:25183871)
PMID:21873635
RGD PMID:25183871, PMID:21873635 RGD:13792537 NCBI chr 1:204,714,468...204,805,738
Ensembl chr 1:204,714,473...204,817,080
JBrowse link
G Fgf10 fibroblast growth factor 10 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1859647 (MGI:3629001|PMID:16720875)
RGD PMID:16720875, PMID:21873635 MGI:3629001, RGD:13792537 NCBI chr 2:51,673,480...51,747,533
Ensembl chr 2:51,672,722...51,750,369
JBrowse link
G Fgf2 fibroblast growth factor 2 acts_upstream_of_or_within ISO (MGI:3701731|PMID:16858399) RGD PMID:16858399 MGI:3701731 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fgf9 fibroblast growth factor 9 acts_upstream_of_or_within ISO MGI:2135961 (MGI:3801531|PMID:18533146) RGD PMID:18533146 MGI:3801531 NCBI chr15:38,341,657...38,386,945
Ensembl chr15:38,341,089...38,387,316
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO MGI:2153811|MGI:95522 (MGI:3629001|PMID:16720875), (MGI:3801531|PMID:18533146) RGD PMID:16720875 PMID:18533146 MGI:3629001 MGI:3801531 NCBI chr 1:200,590,951...200,696,946
Ensembl chr 1:200,590,953...200,696,928
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO MGI:1931521 (MGI:4352984|PMID:19407216) RGD PMID:19407216 MGI:4352984 NCBI chr14:82,272,322...82,287,739
Ensembl chr14:82,273,070...82,287,706
JBrowse link
G Frat1 FRAT regulator of WNT signaling pathway 1 involved_in ISO UniProtKB:O14640 (PMID:12556519) RGD PMID:12556519 NCBI chr 1:261,071,965...261,075,244 JBrowse link
G Fzd9 frizzled class receptor 9 involved_in ISS
ISO
GO_REF:0000024
(MGI:5805361|PMID:24860427)
UniProt
RGD
PMID:24860427 GO_REF:0000024 MGI:5805361 NCBI chr12:24,473,981...24,476,295
Ensembl chr12:24,473,981...24,476,295
JBrowse link
G Gid8 GID complex subunit 8 homolog involved_in ISO
IBA
(PMID:28829046)
PMID:21873635
RGD PMID:28829046, PMID:21873635 RGD:13792537 NCBI chr 3:176,217,128...176,223,645
Ensembl chr 3:176,217,128...176,223,645
JBrowse link
G Gpc3 glypican 3 involved_in ISS
IEA
IBA
ISO
GO_REF:0000024
GO_REF:0000107
PMID:21873635
(PMID:24496449)
UniProt
Ensembl
RGD
PMID:24496449, PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr  X:139,579,268...139,947,093
Ensembl chr  X:139,579,268...139,916,883
JBrowse link
G Gprc5b G protein-coupled receptor, class C, group 5, member B involved_in ISO (MGI:5543849|PMID:24089469) RGD PMID:24089469 MGI:5543849 NCBI chr 1:188,688,743...188,713,724
Ensembl chr 1:188,688,743...188,713,280
JBrowse link
G Gskip GSK3B interacting protein involved_in ISO
IEA
ISS
(PMID:27484798)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:27484798 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:129,512,950...129,536,320
Ensembl chr 6:129,519,709...129,536,221
JBrowse link
G Hhex hematopoietically expressed homeobox involved_in ISO (PMID:20028982) RGD PMID:20028982 NCBI chr 1:256,101,994...256,107,581
Ensembl chr 1:256,101,903...256,107,649
JBrowse link
G Ilk integrin-linked kinase involved_in ISO (PMID:20018240) RGD PMID:20018240 NCBI chr 1:170,578,941...170,585,192
Ensembl chr 1:170,578,889...170,585,189
JBrowse link
G Jrk Jrk helix-turn-helix protein involved_in ISO (PMID:21399610) RGD PMID:21399610 NCBI chr 7:115,941,788...115,946,471
Ensembl chr 7:115,942,743...115,946,425
JBrowse link
G Kank1 KN motif and ankyrin repeat domains 1 involved_in ISO (PMID:16968744) RGD PMID:16968744 NCBI chr 1:243,201,073...243,398,531
Ensembl chr 1:243,276,403...243,398,536
JBrowse link
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 involved_in ISS
ISO
GO_REF:0000024
(MGI:5141327|PMID:21727895), (MGI:5494789|PMID:23393138), (MGI:5499719|PMID:21693646)
(PMID:22815884)
UniProt
RGD
PMID:21693646 PMID:21727895 PMID:22815884 PMID:23393138 GO_REF:0000024 MGI:5141327 MGI:5494789 MGI:5499719 NCBI chr 3:101,051,960...101,152,119
Ensembl chr 3:101,051,955...101,152,119
JBrowse link
G Lgr5 leucine rich repeat containing G protein coupled receptor 5 involved_in ISO
ISS
(PMID:21693646), (PMID:22815884)
(MGI:5141327|PMID:21727895)
GO_REF:0000024
RGD
UniProt
PMID:21693646 PMID:21727895 PMID:22815884 GO_REF:0000024 MGI:5141327 NCBI chr 7:58,447,097...58,587,787
Ensembl chr 7:58,448,277...58,587,787
JBrowse link
G Lrrk1 leucine-rich repeat kinase 1 involved_in ISO UniProtKB:O14640 (PMID:22899650) RGD PMID:22899650 NCBI chr 1:127,166,866...127,301,053
Ensembl chr 1:127,166,431...127,292,090
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO UniProtKB:O14640|UniProtKB:O14641|UniProtKB:O75581|UniProtKB:Q92997 (PMID:22899650) RGD PMID:22899650 NCBI chr 7:132,857,311...133,018,549
Ensembl chr 7:132,857,628...133,018,584
JBrowse link
G Lypd6 LY6/PLAUR domain containing 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:35,566,956...35,707,416
Ensembl chr 3:35,679,750...35,707,410
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:20018240)
Ensembl
RGD
PMID:20018240 GO_REF:0000107 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nle1 notchless homolog 1 acts_upstream_of_or_within ISO MGI:2671871|MGI:2671874 (MGI:5468737|PMID:23231322) RGD PMID:23231322 MGI:5468737 NCBI chr10:70,250,959...70,261,880
Ensembl chr10:70,250,959...70,259,553
JBrowse link
G Nrarp Notch-regulated ankyrin repeat protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:2,396,143...2,398,697
Ensembl chr 3:2,396,143...2,398,689
JBrowse link
G Peg12 paternally expressed 12 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:123,097,861...123,100,464
Ensembl chr 1:123,097,861...123,100,464
JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 involved_in ISO (PMID:11533658) RGD PMID:11533658 NCBI chr 8:21,669,236...21,680,615
Ensembl chr 8:21,669,236...21,680,615
JBrowse link
G Plekha4 pleckstrin homology domain containing A4 involved_in ISO
IBA
(PMID:31091453)
PMID:21873635
RGD PMID:31091453, PMID:21873635 RGD:13792537 NCBI chr 1:101,517,702...101,540,802
Ensembl chr 1:101,517,714...101,540,802
JBrowse link
G Pou5f1 POU class 5 homeobox 1 involved_in ISO (PMID:19736317) RGD PMID:19736317 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994
JBrowse link
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent, 1A involved_in ISO
IBA
IEA
(PMID:10644691)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:10644691, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 6:94,433,658...94,484,979
Ensembl chr 6:94,429,068...94,484,351
JBrowse link
G Ppm1b protein phosphatase, Mg2+/Mn2+ dependent, 1B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:8,219,385...8,280,127
Ensembl chr 6:8,218,696...8,280,124
JBrowse link
G Ppm1n protein phosphatase, Mg2+/Mn2+ dependent 1N involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:80,190,293...80,193,002 JBrowse link
G Ppp2r3a protein phosphatase 2, regulatory subunit B'', alpha involved_in ISO (PMID:16567647) RGD PMID:16567647 NCBI chr 8:109,481,352...109,621,462
Ensembl chr 8:109,482,614...109,621,408
JBrowse link
G Prdm15 PR/SET domain 15 involved_in ISO (MGI:6120615|PMID:28740264) RGD PMID:28740264 MGI:6120615 NCBI chr11:38,294,040...38,354,648
Ensembl chr11:38,293,875...38,351,184
JBrowse link
G Ptk7 protein tyrosine kinase 7 involved_in ISO (PMID:21132015) RGD PMID:21132015 NCBI chr 9:16,662,588...16,729,888
Ensembl chr 9:16,702,460...16,729,030
JBrowse link
G Reck reversion-inducing-cysteine-rich protein with kazal motifs involved_in ISO (MGI:6114565|PMID:28803732), (MGI:6255947|PMID:30026314) RGD PMID:28803732 PMID:30026314 MGI:6114565 MGI:6255947 NCBI chr 5:59,348,568...59,415,169
Ensembl chr 5:59,348,639...59,415,135
JBrowse link
G Rnf146 ring finger protein 146 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:21478859)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:21478859 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:30,856,923...30,873,814
Ensembl chr 1:30,863,217...30,873,808
JBrowse link
G Rnf220 ring finger protein 220 involved_in ISO (PMID:25266658) RGD PMID:25266658 NCBI chr 5:136,129,457...136,351,752
Ensembl chr 5:136,129,425...136,166,786
JBrowse link
G Ror2 receptor tyrosine kinase-like orphan receptor 2 involved_in ISO (MGI:4835141|PMID:18215320) RGD PMID:18215320 MGI:4835141 NCBI chr17:11,953,552...12,134,386
Ensembl chr17:11,953,552...12,134,386
JBrowse link
G Rspo1 R-spondin 1 involved_in ISO (PMID:17804805), (PMID:22815884)
(MGI:5499719|PMID:21693646)
RGD PMID:17804805 PMID:21693646 PMID:22815884 MGI:5499719 NCBI chr 5:142,986,526...143,007,847
Ensembl chr 5:142,986,526...143,007,831
JBrowse link
G Rspo2 R-spondin 2 acts_upstream_of_or_within ISO MGI:1298218|MGI:3045965 (MGI:3774879|PMID:18256198), (MGI:3850932|PMID:19213727) RGD PMID:18256198 PMID:19213727 MGI:3774879 MGI:3850932 NCBI chr 7:81,919,911...82,059,659
Ensembl chr 7:81,924,050...82,059,789
JBrowse link
G Rspo3 R-spondin 3 acts_upstream_of_or_within ISO MGI:5609537 (MGI:3664518|PMID:16543246), (MGI:5606157|PMID:18842812) RGD PMID:16543246 PMID:18842812 MGI:3664518 MGI:5606157 NCBI chr 1:30,681,648...30,768,038
Ensembl chr 1:30,681,681...30,766,860
JBrowse link
G Ruvbl1 RuvB-like AAA ATPase 1 involved_in ISO (PMID:11080158) RGD PMID:11080158 NCBI chr 4:120,411,917...120,447,458
Ensembl chr 4:120,411,991...120,447,455
JBrowse link
G Scel sciellin involved_in ISO (PMID:27013588) RGD PMID:27013588 NCBI chr15:87,689,190...87,820,731
Ensembl chr15:87,704,340...87,820,779
JBrowse link
G Sema5a semaphorin 5A involved_in ISS
ISO
GO_REF:0000024
(MGI:5526935|PMID:19850054)
UniProt
RGD
PMID:19850054 GO_REF:0000024 MGI:5526935 NCBI chr 2:85,377,318...85,808,970
Ensembl chr 2:85,377,318...85,808,970
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in ISO
IEA
UniProtKB:P27467|UniProtKB:Q13467 (PMID:18941195), (PMID:24080158)
GO_REF:0000107
RGD
Ensembl
PMID:18941195 PMID:24080158 GO_REF:0000107 NCBI chr16:73,372,007...73,410,777
Ensembl chr16:73,372,007...73,410,777
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 involved_in
acts_upstream_of_or_within
IGI
ISO
PMID:24080158
MGI:98956 (MGI:3772759|PMID:18166153)
(MGI:4837797|PMID:20723538), (MGI:5700300|PMID:19001373)
RGD PMID:18166153 PMID:19001373 PMID:20723538, PMID:24080158 MGI:3772759 MGI:4837797 MGI:5700300, RGD:10448946 NCBI chr 2:182,723,732...182,731,277
Ensembl chr 2:182,723,854...182,731,764
JBrowse link
G Sfrp4 secreted frizzled-related protein 4 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr17:47,383,983...47,394,065
Ensembl chr17:47,297,489...47,394,328
JBrowse link
G Smad3 SMAD family member 3 involved_in IMP PMID:20097766 BHF-UCL PMID:20097766 RGD:11079190 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
G Sox4 SRY-box transcription factor 4 involved_in ISO (MGI:3768575|PMID:17875931) RGD PMID:17875931 MGI:3768575 NCBI chr17:37,615,022...37,619,728 JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:98956|UniProtKB:Q08463 (MGI:4414728|PMID:19920076) RGD PMID:19920076 MGI:4414728 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Sulf2 sulfatase 2 acts_upstream_of_or_within ISO MGI:3587954 (MGI:5515698|PMID:23740243) RGD PMID:23740243 MGI:5515698 NCBI chr 3:162,791,349...162,872,984
Ensembl chr 3:162,791,355...162,872,831
JBrowse link
G Tbl1x transducin (beta)-like 1 X-linked involved_in ISO (PMID:18193033) RGD PMID:18193033 NCBI chr  X:44,959,883...44,988,551
Ensembl chr  X:44,830,849...44,988,551
JBrowse link
G Tbl1xr1 TBL1X receptor 1 involved_in ISO (PMID:18193033) RGD PMID:18193033 NCBI chr 2:107,221,913...107,359,229
Ensembl chr 2:107,233,054...107,359,229
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO (PMID:12893825), (PMID:15040835) RGD PMID:12893825 PMID:15040835 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tmem198 transmembrane protein 198 involved_in IBA
ISO
PMID:21873635
(PMID:21536646)
RGD PMID:21536646, PMID:21873635 RGD:13792537 NCBI chr 9:82,673,959...82,680,151
Ensembl chr 9:82,674,202...82,679,626
JBrowse link
G Tmem198b transmembrane protein 198b involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:3,224,831...3,230,129
Ensembl chr 7:3,224,833...3,229,167
JBrowse link
G Tmem9 transmembrane protein 9 involved_in ISO (PMID:30374053)
(MGI:6271361|PMID:30374053)
RGD PMID:30374053 MGI:6271361 NCBI chr13:52,854,031...52,871,300
Ensembl chr13:52,854,031...52,871,297
JBrowse link
G Tnks tankyrase involved_in ISO
IBA
(PMID:19759537), (PMID:25939383)
PMID:21873635
RGD PMID:19759537 PMID:25939383, PMID:21873635 RGD:13792537 NCBI chr16:60,925,093...61,067,192
Ensembl chr16:60,925,093...61,067,192
JBrowse link
G Tnks2 tankyrase 2 involved_in IBA
ISO
PMID:21873635
(PMID:19759537), (PMID:25939383)
RGD PMID:19759537 PMID:25939383, PMID:21873635 RGD:13792537 NCBI chr 1:255,478,794...255,532,143
Ensembl chr 1:255,479,261...255,532,143
JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 involved_in ISO
IEA
ISS
(PMID:20625999)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:20625999 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:101,293,300...101,323,484
Ensembl chr 1:101,293,409...101,323,960
JBrowse link
G Ttc21b tetratricopeptide repeat domain 21B acts_upstream_of_or_within ISO MGI:2152544|MGI:2669525|MGI:5587034 (MGI:5789453|PMID:27482817) RGD PMID:27482817 MGI:5789453 NCBI chr 3:52,286,794...52,361,060
Ensembl chr 3:52,286,794...52,361,060
JBrowse link
G Ube2b ubiquitin-conjugating enzyme E2B involved_in ISO (MGI:3852303|PMID:18339854) RGD PMID:18339854 MGI:3852303 NCBI chr10:37,439,947...37,454,867
Ensembl chr10:37,441,284...37,455,022
JBrowse link
G Ubr5 ubiquitin protein ligase E3 component n-recognin 5 involved_in IEA
ISO
GO_REF:0000107
(PMID:21118991), (PMID:28689657)
Ensembl
RGD
PMID:21118991 PMID:28689657 GO_REF:0000107 NCBI chr 7:76,789,110...76,835,517
NCBI chr 7:76,839,661...76,907,441
Ensembl chr 7:76,789,531...76,853,840
JBrowse link
G Usp34 ubiquitin specific peptidase 34 involved_in ISO (PMID:21383061) RGD PMID:21383061 NCBI chr14:108,060,653...108,264,706
Ensembl chr14:108,143,869...108,264,706
JBrowse link
G Usp47 ubiquitin specific peptidase 47 involved_in ISO (PMID:26169834) RGD PMID:26169834 NCBI chr 1:176,854,589...176,937,763
Ensembl chr 1:176,854,653...176,937,763
JBrowse link
G Usp8 ubiquitin specific peptidase 8 involved_in ISO (PMID:20495530) RGD PMID:20495530 NCBI chr 3:119,173,818...119,222,499
Ensembl chr 3:119,173,818...119,222,484
JBrowse link
G Vcp valosin-containing protein involved_in ISO (PMID:28689657) RGD PMID:28689657 NCBI chr 5:58,426,548...58,445,953
Ensembl chr 5:58,426,549...58,445,953
JBrowse link
G Vps35 VPS35 retromer complex component involved_in ISO UniProtKB:P04426 (MGI:5693230|PMID:17239604) RGD PMID:17239604 MGI:5693230 NCBI chr19:27,464,937...27,500,636
Ensembl chr19:27,464,937...27,500,636
JBrowse link
G Wls Wnt ligand secretion mediator involved_in ISO (PMID:17804805)
(MGI:4834980|PMID:20614471)
RGD PMID:17804805 PMID:20614471 MGI:4834980 NCBI chr 2:266,315,036...266,431,220
Ensembl chr 2:266,315,036...266,432,558
JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 involved_in ISO (PMID:23797875) RGD PMID:23797875 NCBI chr 4:152,452,211...152,578,469
Ensembl chr 4:152,452,848...152,578,446
JBrowse link
G Wnk2 WNK lysine deficient protein kinase 2 involved_in ISO (PMID:23797875) RGD PMID:23797875 NCBI chr17:15,923,508...16,032,271
Ensembl chr17:15,924,048...16,032,420
JBrowse link
G Wnt10b Wnt family member 10B acts_upstream_of_or_within ISO (MGI:4358631|PMID:19723499) RGD PMID:19723499 MGI:4358631 NCBI chr 7:140,448,284...140,466,159
Ensembl chr 7:140,448,465...140,454,268
JBrowse link
G Wnt3a Wnt family member 3A involved_in
acts_upstream_of_or_within
ISO (PMID:20137080), (PMID:20723538)
(MGI:3772496|PMID:18155657), (MGI:5515698|PMID:23740243)
RGD PMID:18155657 PMID:20137080 PMID:20723538 PMID:23740243 MGI:3772496 MGI:5515698 NCBI chr10:45,598,898...45,643,151
Ensembl chr10:45,598,912...45,638,035
JBrowse link
G Xiap X-linked inhibitor of apoptosis involved_in IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
(PMID:22304967)
Ensembl
RGD
PMID:22304967, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr  X:128,409,425...128,455,786
Ensembl chr  X:128,409,472...128,453,000
JBrowse link
G Yap1 Yes1 associated transcriptional regulator acts_upstream_of_or_within ISO (MGI:3818355|PMID:17980593) RGD PMID:17980593 MGI:3818355 NCBI chr 8:6,133,014...6,204,240
Ensembl chr 8:6,135,493...6,203,579
JBrowse link
G Zbed3 zinc finger, BED-type containing 3 acts_upstream_of_or_within ISO (MGI:3844787|PMID:19141611) RGD PMID:19141611 MGI:3844787 NCBI chr 2:25,039,506...25,052,129
Ensembl chr 2:25,041,185...25,052,127
JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 involved_in ISO
IEA
(PMID:30592286)
GO_REF:0000107
RGD
Ensembl
PMID:30592286 GO_REF:0000107 NCBI chr 3:29,857,289...29,985,932
Ensembl chr 3:29,862,473...29,996,865
JBrowse link
positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rbpj recombination signal binding protein for immunoglobulin kappa J region acts_upstream_of_or_within ISO MGI:3583755 (MGI:5432296|PMID:22711842) RGD PMID:22711842 MGI:5432296 NCBI chr14:59,657,738...59,865,427
Ensembl chr14:59,658,935...59,735,450
JBrowse link
positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a Wnt family member 3A involved_in ISO (MGI:4835142|PMID:17994217) RGD PMID:17994217 MGI:4835142 NCBI chr10:45,598,898...45,643,151
Ensembl chr10:45,598,912...45,638,035
JBrowse link
positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (MGI:3835736|PMID:18297060) RGD PMID:18297060 MGI:3835736 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607
Ensembl chr 1:248,895,738...248,898,607
JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in ISO (MGI:3835736|PMID:18297060) RGD PMID:18297060 MGI:3835736 NCBI chr 1:141,532,390...141,533,908
Ensembl chr 1:141,532,390...141,533,908
JBrowse link
G Wnt11 Wnt family member 11 involved_in ISO UniProtKB:P22725 (MGI:5424267|PMID:22569553) RGD PMID:22569553 MGI:5424267 NCBI chr 1:163,794,136...163,813,756
Ensembl chr 1:163,797,660...163,813,756
JBrowse link
G Wnt5a Wnt family member 5A involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P48615 (MGI:5424267|PMID:22569553)
Ensembl
RGD
PMID:22569553 GO_REF:0000107 MGI:5424267 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
receptor internalization involved in canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:16890161)
Ensembl
RGD
PMID:16890161 GO_REF:0000107 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Rab5a RAB5A, member RAS oncogene family involved_in ISO (PMID:16890161) RGD PMID:16890161 NCBI chr 9:5,910...6,065 JBrowse link
G Scyl2 SCY1 like pseudokinase 2 involved_in ISO (PMID:19643732) RGD PMID:19643732 NCBI chr 7:30,291,087...30,344,464
Ensembl chr 7:30,291,087...30,344,445
JBrowse link
regulation of canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amer1 APC membrane recruitment protein 1 involved_in IBA
ISO
PMID:21873635
(PMID:17925383)
RGD PMID:17925383, PMID:21873635 RGD:13792537 NCBI chr  X:64,686,620...64,702,504
Ensembl chr  X:64,686,623...64,702,441
JBrowse link
G Amer2 APC membrane recruitment protein 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:40,663,183...40,667,705
Ensembl chr15:40,665,041...40,667,173
JBrowse link
G Amer3 APC membrane recruitment protein 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:41,089,417...41,101,108
Ensembl chr 9:41,096,835...41,099,189
JBrowse link
G Axin1 axin 1 acts_upstream_of_or_within ISO (MGI:3036437|PMID:14981260) RGD PMID:14981260 MGI:3036437
G Btrc beta-transducin repeat containing E3 ubiquitin protein ligase involved_in ISO (MGI:5705222|PMID:18929646) RGD PMID:18929646 MGI:5705222 NCBI chr 1:265,100,094...265,270,263
Ensembl chr 1:265,157,379...265,269,837
JBrowse link
G Ccny cyclin Y involved_in ISO (PMID:20059949) RGD PMID:20059949 NCBI chr17:62,332,537...62,462,644
Ensembl chr17:62,332,537...62,462,644
JBrowse link
G Cdk14 cyclin-dependent kinase 14 involved_in ISO (PMID:20059949) RGD PMID:20059949 NCBI chr 4:25,825,567...26,419,443
Ensembl chr 4:25,825,567...26,419,127
JBrowse link
G Ctnnd2 catenin delta 2 involved_in ISO
IEA
(PMID:25807484)
GO_REF:0000107
RGD
Ensembl
PMID:25807484 GO_REF:0000107 NCBI chr 2:83,227,247...84,094,315
Ensembl chr 2:83,393,282...84,094,315
JBrowse link
G Daam2 dishevelled associated activator of morphogenesis 2 involved_in ISO (MGI:5638274|PMID:25754822) RGD PMID:25754822 MGI:5638274 NCBI chr 9:13,444,883...13,493,154
Ensembl chr 9:13,446,896...13,490,669
JBrowse link
G Dact1 dishevelled-binding antagonist of beta-catenin 1 involved_in ISO (PMID:18936100) RGD PMID:18936100 NCBI chr 6:93,740,440...93,751,003
Ensembl chr 6:93,740,586...93,749,809
JBrowse link
G Emd emerin involved_in ISO (PMID:16858403) RGD PMID:16858403 NCBI chr  X:156,452,847...156,455,858
Ensembl chr  X:156,452,818...156,456,035
JBrowse link
G Fam53b family with sequence similarity 53, member B involved_in ISO (PMID:25183871) RGD PMID:25183871 NCBI chr 1:204,714,468...204,805,738
Ensembl chr 1:204,714,473...204,817,080
JBrowse link
G Folr1 folate receptor alpha involved_in ISO (MGI:5644149|PMID:21649587) RGD PMID:21649587 MGI:5644149 NCBI chr 1:166,934,457...166,945,864
Ensembl chr 1:166,934,460...166,943,592
JBrowse link
G Fzd7 frizzled class receptor 7 involved_in ISO (PMID:9707618) RGD PMID:9707618 NCBI chr 9:66,305,731...66,308,550
Ensembl chr 9:66,305,731...66,308,550
JBrowse link
G Gnaq G protein subunit alpha q involved_in ISO (PMID:20399743) RGD PMID:20399743 NCBI chr 1:233,382,778...233,622,584
Ensembl chr 1:233,382,708...233,622,786
JBrowse link
G Gpc3 glypican 3 involved_in ISO (PMID:14610063) RGD PMID:14610063 NCBI chr  X:139,579,268...139,947,093
Ensembl chr  X:139,579,268...139,916,883
JBrowse link
G Ift20 intraflagellar transport 20 acts_upstream_of_or_within ISO MGI:3817268 (MGI:3815342|PMID:18981227) RGD PMID:18981227 MGI:3815342 NCBI chr10:65,805,808...65,811,353
Ensembl chr10:65,805,860...65,811,351
JBrowse link
G Kpna1 karyopherin subunit alpha 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3775202 (MGI:5823554|PMID:27434733)
Ensembl
RGD
PMID:27434733 GO_REF:0000107 MGI:5823554 NCBI chr11:67,652,573...67,717,180
Ensembl chr11:67,652,577...67,703,025
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in IBA
ISO
PMID:21873635
UniProtKB:O35625|UniProtKB:P51141|UniProtKB:Q02248|UniProtKB:Q9WV60 (MGI:5440351|PMID:22899650)
RGD PMID:22899650, PMID:21873635 MGI:5440351, RGD:13792537 NCBI chr 7:132,857,311...133,018,549
Ensembl chr 7:132,857,628...133,018,584
JBrowse link
G Mks1 MKS transition zone complex subunit 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:4433029 (MGI:5487695|PMID:23454480)
Ensembl
RGD
PMID:23454480 GO_REF:0000107 MGI:5487695 NCBI chr10:75,149,814...75,160,481
Ensembl chr10:75,149,814...75,160,480
JBrowse link
G Otulin OTU deubiquitinase with linear linkage specificity involved_in ISO (MGI:5494328|PMID:23708998) RGD PMID:23708998 MGI:5494328 NCBI chr 2:80,267,724...80,293,204
Ensembl chr 2:80,269,587...80,293,181
JBrowse link
G Psen1 presenilin 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:2150214|PMID:11517342)
UniProt
RGD
PMID:11517342 GO_REF:0000024 MGI:2150214 NCBI chr 6:107,169,514...107,221,000
Ensembl chr 6:107,169,528...107,216,798
JBrowse link
G Ptk7 protein tyrosine kinase 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:16,662,588...16,729,888
Ensembl chr 9:16,702,460...16,729,030
JBrowse link
G Ror2 receptor tyrosine kinase-like orphan receptor 2 acts_upstream_of_or_within ISO MGI:3793279 (MGI:4822496|PMID:20660756) RGD PMID:20660756 MGI:4822496 NCBI chr17:11,953,552...12,134,386
Ensembl chr17:11,953,552...12,134,386
JBrowse link
G Sox7 SRY-box transcription factor 7 involved_in ISO (PMID:19108950) RGD PMID:19108950 NCBI chr15:47,293,699...47,300,460
Ensembl chr15:47,293,699...47,300,460
JBrowse link
G Wwtr1 WW domain containing transcription regulator 1 acts_upstream_of_or_within ISO MGI:103262 (MGI:5514437|PMID:23974041) RGD PMID:23974041 MGI:5514437 NCBI chr 2:147,577,149...147,693,033
Ensembl chr 2:147,577,089...147,693,082
JBrowse link
G Yap1 Yes1 associated transcriptional regulator acts_upstream_of_or_within ISO MGI:1917649 (MGI:5514437|PMID:23974041) RGD PMID:23974041 MGI:5514437 NCBI chr 8:6,133,014...6,204,240
Ensembl chr 8:6,135,493...6,203,579
JBrowse link
G Zfp703 zinc finger protein 703 involved_in ISO (MGI:4940410|PMID:21317240) RGD PMID:21317240 MGI:4940410 NCBI chr16:69,237,857...69,242,028
Ensembl chr16:69,237,857...69,242,028
JBrowse link
G Znrf3 zinc and ring finger 3 involved_in ISO (MGI:5424263|PMID:22575959) RGD PMID:22575959 MGI:5424263 NCBI chr14:85,527,099...85,586,294 JBrowse link
regulation of hair cycle by canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdh3 cadherin 3 involved_in ISO (PMID:22696062) RGD PMID:22696062 NCBI chr19:38,668,957...38,719,801
Ensembl chr19:38,669,230...38,719,677
JBrowse link
regulation of heart induction by regulation of canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pou5f1 POU class 5 homeobox 1 involved_in ISO (PMID:19736317) RGD PMID:19736317 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19638
    signaling 7507
      cell-cell signaling 1722
        cell-cell signaling by wnt 434
          Wnt signaling pathway 431
            canonical Wnt signaling pathway 294
              beta-catenin destruction complex disassembly 0
              canonical Wnt signaling pathway involved in heart development + 6
              canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation 3
              canonical Wnt signaling pathway involved in mesonephros development + 0
              canonical Wnt signaling pathway involved in metanephric kidney development + 2
              canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation 3
              canonical Wnt signaling pathway involved in negative regulation of apoptotic process 4
              canonical Wnt signaling pathway involved in neural crest cell differentiation + 1
              canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation + 1
              canonical Wnt signaling pathway involved in osteoblast differentiation + 3
              canonical Wnt signaling pathway involved in positive regulation of apoptotic process 2
              canonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion 1
              canonical Wnt signaling pathway involved in positive regulation of endothelial cell migration 1
              canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition 2
              canonical Wnt signaling pathway involved in positive regulation of wound healing 1
              canonical Wnt signaling pathway involved in regulation of cell proliferation + 6
              negative regulation of canonical Wnt signaling pathway + 130
              positive regulation of canonical Wnt signaling pathway + 106
              positive regulation of spinal cord association neuron differentiation by canonical Wnt signaling pathway + 0
              receptor internalization involved in canonical Wnt signaling pathway 3
              regulation of canonical Wnt signaling pathway + 241
              regulation of hair cycle by canonical Wnt signaling pathway 1
              regulation of heart induction by canonical Wnt signaling pathway + 6
Path 2
Term Annotations click to browse term
  biological_process 19638
    biological regulation 13583
      regulation of biological process 12829
        regulation of cellular process 12327
          signal transduction 6936
            cell surface receptor signaling pathway 2754
              cell surface receptor signaling pathway involved in cell-cell signaling 557
                Wnt signaling pathway 431
                  canonical Wnt signaling pathway 294
                    beta-catenin destruction complex disassembly 0
                    canonical Wnt signaling pathway involved in heart development + 6
                    canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation 3
                    canonical Wnt signaling pathway involved in mesonephros development + 0
                    canonical Wnt signaling pathway involved in metanephric kidney development + 2
                    canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation 3
                    canonical Wnt signaling pathway involved in negative regulation of apoptotic process 4
                    canonical Wnt signaling pathway involved in neural crest cell differentiation + 1
                    canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation + 1
                    canonical Wnt signaling pathway involved in osteoblast differentiation + 3
                    canonical Wnt signaling pathway involved in positive regulation of apoptotic process 2
                    canonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion 1
                    canonical Wnt signaling pathway involved in positive regulation of endothelial cell migration 1
                    canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition 2
                    canonical Wnt signaling pathway involved in positive regulation of wound healing 1
                    canonical Wnt signaling pathway involved in regulation of cell proliferation + 6
                    negative regulation of canonical Wnt signaling pathway + 130
                    positive regulation of canonical Wnt signaling pathway + 106
                    positive regulation of spinal cord association neuron differentiation by canonical Wnt signaling pathway + 0
                    receptor internalization involved in canonical Wnt signaling pathway 3
                    regulation of canonical Wnt signaling pathway + 241
                    regulation of hair cycle by canonical Wnt signaling pathway 1
                    regulation of heart induction by canonical Wnt signaling pathway + 6
paths to the root