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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of cardiac muscle cell proliferation
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Accession:GO:0060043 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation.
Synonyms:exact_synonym: regulation of heart muscle cell proliferation
 related_synonym: regulation of cardiomyocyte proliferation


show annotations for term's descendants           Sort by:
regulation of cardiac muscle cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (PMID:15073157) RGD PMID:15073157 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616 		JBrowse link
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A IMP RGD PMID:27056896 RGD:401959209 NCBI chr11:33,890,706...34,009,420
Ensembl chr11:33,890,490...34,009,420 		JBrowse link
G Fgf20 fibroblast growth factor 20 acts_upstream_of_or_within ISO MGI:1914004 (PMID:20713518) RGD PMID:20713518 NCBI chr16:52,030,549...52,038,201
Ensembl chr16:52,010,194...52,038,204 		JBrowse link
G Foxp1 forkhead box P1 acts_upstream_of_or_within ISO MGI:1891346 (PMID:20713518) RGD PMID:20713518 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G Gata4 GATA binding protein 4 acts_upstream_of_or_within ISO MGI:3526854 (PMID:15902305) RGD PMID:15902305 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Mapk11 mitogen-activated protein kinase 11 acts_upstream_of_or_within ISO MGI:1346865 (PMID:21768366) RGD PMID:21768366 NCBI chr 7:120,218,471...120,225,488
Ensembl chr 7:120,218,478...120,225,395 		JBrowse link
G Mir133a1 microRNA 133a-1 acts_upstream_of_or_within ISO MGI:3822152|MGI:3822154 (PMID:19015276) RGD PMID:19015276 NCBI chr18:1,885,082...1,885,168 JBrowse link
G Mir3582 microRNA 3582 acts_upstream_of_or_within ISO MGI:3822156|MGI:3822158 (PMID:19015276) RGD PMID:19015276 NCBI chr18:1,885,063...1,885,180
Ensembl chr18:1,885,063...1,885,180 		JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:20713518)		 Ensembl
RGD		 PMID:20713518 GO_REF:0000107 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:18718461)		 Ensembl
RGD		 PMID:18718461 GO_REF:0000107 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777 		JBrowse link
negative regulation of cardiac muscle cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway involved_in IMP PMID:28948298 BHF-UCL PMID:28948298 RGD:13464260 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 involved_in IMP PMID:26240138 BHF-UCL PMID:26240138 RGD:13210532 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897 		JBrowse link
G Cxadr CXADR, Ig-like cell adhesion molecule acts_upstream_of_or_within ISO MGI:3711226 (PMID:16543498) RGD PMID:16543498 NCBI chr11:16,982,864...17,030,078
Ensembl chr11:16,982,860...17,030,046 		JBrowse link
G Gja1 gap junction protein, alpha 1 IMP RGD PMID:19377854 RGD:7207421 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Hdac2 histone deacetylase 2 acts_upstream_of_or_within ISO MGI:3712002 (PMID:17322895) RGD PMID:17322895 NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609 		JBrowse link
G Jarid2 jumonji and AT-rich interaction domain containing 2 involved_in
acts_upstream_of_or_within		 IMP
ISO
IDA		 PMID:26298346
MGI:1856923 (PMID:15870077)		 RGD PMID:15870077 PMID:26298346 PMID:26298346 RGD:11522645, RGD:11522645 NCBI chr17:19,777,487...19,957,696
Ensembl chr17:19,777,266...19,955,690 		JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 IMP RGD PMID:24705172 RGD:9831164 NCBI chr13:100,766,101...100,963,435
Ensembl chr13:100,766,113...100,963,435 		JBrowse link
G Mapk11 mitogen-activated protein kinase 11 acts_upstream_of_or_within ISO MGI:3609429 (PMID:21768366) RGD PMID:21768366 NCBI chr 7:120,218,471...120,225,488
Ensembl chr 7:120,218,478...120,225,395 		JBrowse link
G Mir1 microRNA 1 acts_upstream_of_or_within ISO (PMID:17397913) RGD PMID:17397913 NCBI chr18:1,887,537...1,887,623 JBrowse link
G Mir873 microRNA 873 involved_in ISO (PMID:28583401) RGD PMID:28583401 NCBI chr 5:51,356,919...51,356,995
Ensembl chr 5:51,356,919...51,356,995 		JBrowse link
G Nog noggin involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:17218603)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:17218603 GO_REF:0000024 GO_REF:0000107 NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339 		JBrowse link
G Pten phosphatase and tensin homolog involved_in IMP
ISO		 RNAcentral:URS000006FDD4_10090|RNAcentral:URS000013D17D_10090 (PMID:23575307) RGD PMID:23575307 PMID:30783439 RGD:150527846 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Rbp4 retinol binding protein 4 involved_in ISO (PMID:12663486) RGD PMID:12663486 NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399 		JBrowse link
G Sav1 salvador family WW domain containing protein 1 acts_upstream_of_or_within ISO MGI:2654594|MGI:4430538 (PMID:21512031) RGD PMID:21512031 NCBI chr 6:88,478,536...88,500,121
Ensembl chr 6:88,478,539...88,499,968 		JBrowse link
G Tbx5 T-box transcription factor 5 involved_in ISO
IEA
ISS		 (PMID:11161571)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:11161571 GO_REF:0000024 GO_REF:0000107 NCBI chr12:36,686,344...36,739,253
Ensembl chr12:36,688,014...36,734,885 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 IMP RGD PMID:15537505 RGD:1601597 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
G Tp73 tumor protein p73 acts_upstream_of_or_within ISO (PMID:18634800) RGD PMID:18634800 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128 		JBrowse link
G Vgll4 vestigial-like family member 4 involved_in ISO (PMID:27720608) RGD PMID:27720608 NCBI chr 4:147,925,630...148,038,519
Ensembl chr 4:147,927,034...148,038,471 		JBrowse link
positive regulation of cardiac muscle cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp10 bone morphogenetic protein 10 involved_in IEA
ISO		 GO_REF:0000107
(PMID:17336907)		 Ensembl
RGD		 PMID:17336907 GO_REF:0000107 NCBI chr 4:119,872,066...119,877,694
Ensembl chr 4:119,872,045...119,878,627 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (PMID:18667463) RGD PMID:18667463 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616 		JBrowse link
G Ccnb1 cyclin B1 IDA RGD PMID:15253691 RGD:2301353 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccnd2 cyclin D2 IDA RGD PMID:27302109 RGD:151660350 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 IMP RGD PMID:15253691 RGD:2301353 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:19632177)		 UniProt
Ensembl
RGD		 PMID:19632177 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595 		JBrowse link
G Fgf2 fibroblast growth factor 2 involved_in IDA
ISO		 (PMID:9553078) RGD PMID:9553078 PMID:8603495 RGD:8655650 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fgf9 fibroblast growth factor 9 acts_upstream_of_or_within ISO MGI:2135961|MGI:95522|MGI:95523 (PMID:15621532), (PMID:16778080) RGD PMID:15621532 PMID:16778080 NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 acts_upstream_of_or_within IMP
ISO		 MGI:104723|MGI:95523 (PMID:15621532), (PMID:16778080) RGD PMID:15621532 PMID:16778080 PMID:18275970 RGD:10402047 NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO MGI:104723|MGI:95522 (PMID:15621532), (PMID:16778080) RGD PMID:15621532 PMID:16778080 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Gata4 GATA binding protein 4 acts_upstream_of_or_within ISO MGI:102541 (PMID:19084512) RGD PMID:19084512 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Gata6 GATA binding protein 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:102541 (PMID:19084512)		 Ensembl
RGD		 PMID:19084512 GO_REF:0000107 NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532 		JBrowse link
G Gli1 GLI family zinc finger 1 involved_in ISO (PMID:28583401) RGD PMID:28583401 NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251 		JBrowse link
G H19 H19 imprinted maternally expressed transcript IMP RGD PMID:27318893 RGD:156430318 NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 acts_upstream_of_or_within ISO MGI:2447620 (PMID:17332425) RGD PMID:17332425 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 IMP RGD PMID:26884868 RGD:13800890 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1338024 (PMID:21768366)		 Ensembl
RGD		 PMID:21768366 GO_REF:0000107 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISS
ISO		 GO_REF:0000024
(PMID:16680724)		 UniProt
RGD		 PMID:16680724 GO_REF:0000024 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
G Mir222 microRNA 222 IMP RGD PMID:25863248 RGD:152025190 NCBI chr  X:3,428,904...3,429,006
Ensembl chr  X:3,428,904...3,429,006 		JBrowse link
G Mir494 microRNA 494 IDA RGD PMID:30783439 RGD:150527846 NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793 		JBrowse link
G Ncam1 neural cell adhesion molecule 1 IMP RGD PMID:19853610 RGD:2325979 NCBI chr 8:49,865,629...50,165,687
Ensembl chr 8:49,865,633...50,166,014 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (PMID:20007915) RGD PMID:20007915 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Nrg1 neuregulin 1 involved_in ISO (PMID:9553078) RGD PMID:9553078 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase involved_in ISO (PMID:21474815) RGD PMID:21474815 NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO (PMID:17336907) RGD PMID:17336907 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353 		JBrowse link
G Tbx1 T-box transcription factor 1 IMP RGD PMID:31982878 RGD:155882591 NCBI chr11:82,409,275...82,419,058
Ensembl chr11:82,409,275...82,418,380 		JBrowse link
G Tbx2 T-box transcription factor 2 involved_in ISO (PMID:15042700) RGD PMID:15042700 NCBI chr10:70,679,670...70,688,868
Ensembl chr10:70,679,518...70,688,529 		JBrowse link
G Tbx20 T-box transcription factor 20 involved_in ISO (PMID:15901664) RGD PMID:15901664 NCBI chr 8:23,200,104...23,258,218
Ensembl chr 8:23,204,507...23,258,175 		JBrowse link
G Tbx5 T-box transcription factor 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:107516|MGI:95664 (PMID:19084512)		 Ensembl
RGD		 PMID:19084512 GO_REF:0000107 NCBI chr12:36,686,344...36,739,253
Ensembl chr12:36,688,014...36,734,885 		JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 involved_in ISO (PMID:12773577) RGD PMID:12773577 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341 		JBrowse link
G Wnt2 Wnt family member 2 acts_upstream_of_or_within ISO MGI:4361155 (PMID:20159597) RGD PMID:20159597 NCBI chr 4:46,328,408...46,374,673
Ensembl chr 4:46,333,998...46,374,402 		JBrowse link
G Yap1 Yes1 associated transcriptional regulator involved_in IEA
ISO		 GO_REF:0000107
(PMID:23918388)		 Ensembl
RGD		 PMID:23918388 GO_REF:0000107 NCBI chr 8:5,095,705...5,166,808
Ensembl chr 8:5,095,722...5,167,010 		JBrowse link
G Zfpm2 zinc finger protein, multitype 2 involved_in ISO RNAcentral:URS000075EEC2_10090 (PMID:22267003) RGD PMID:22267003 NCBI chr 7:71,678,658...72,116,209
Ensembl chr 7:71,678,880...72,116,205 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20075
    cellular process 19154
      cell population proliferation 2267
        regulation of cell population proliferation 1892
          regulation of cardiac muscle cell proliferation 57
            negative regulation of cardiac muscle cell proliferation 18
            positive regulation of cardiac muscle cell proliferation 33
Path 2
Term Annotations click to browse term
  biological_process 20075
    developmental process 7069
      anatomical structure development 6572
        multicellular organism development 5298
          system development 4583
            circulatory system development 1374
              heart development 745
                cardiac muscle tissue development 293
                  cardiac muscle tissue growth 130
                    regulation of cardiac muscle tissue growth 92
                      regulation of cardiac muscle cell proliferation 57
                        negative regulation of cardiac muscle cell proliferation 18
                        positive regulation of cardiac muscle cell proliferation 33
paths to the root