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ONTOLOGY REPORT - ANNOTATIONS


Term:synaptic transmission, glycinergic
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Accession:GO:0060012 term browser browse the term
Definition:The vesicular release of glycine from a presynapse, across a chemical synapse, the subsequent activation of glycine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.


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synaptic transmission, glycinergic term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Glra1 glycine receptor, alpha 1 acts_upstream_of_or_within
involved_in
IDA
ISO
IBA
MGI:1856177|MGI:1856362 (MGI:3623689|PMID:16672662)
(MGI:5707576|PMID:24801766)
PMID:21873635
RGD PMID:16672662 PMID:24801766, PMID:15574743, PMID:21873635 MGI:3623689 MGI:5707576, RGD:1598572, RGD:13792537 NCBI chr10:40,851,955...40,954,364
Ensembl chr10:40,855,559...40,953,651
JBrowse link
G Glra2 glycine receptor, alpha 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:30,612,894...30,832,078
Ensembl chr  X:30,612,903...30,831,483
JBrowse link
G Glra3 glycine receptor, alpha 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:37,676,959...37,908,221
Ensembl chr16:37,676,962...38,063,821
JBrowse link
G Glra4 glycine receptor, alpha 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:107,416,019...107,447,253
Ensembl chr  X:107,422,357...107,442,878
JBrowse link
G Glrb glycine receptor, beta acts_upstream_of_or_within
involved_in
IDA
ISO
IBA
MGI:1856363 (MGI:3621380|PMID:12809985), (MGI:3623689|PMID:16672662), (MGI:49331|PMID:1338094)
PMID:21873635
RGD PMID:1338094 PMID:12809985 PMID:16672662, PMID:15574743, PMID:21873635 MGI:3621380 MGI:3623689 MGI:49331, RGD:1598572, RGD:13792537 NCBI chr 2:179,768,040...179,842,612
Ensembl chr 2:179,769,009...179,842,547
JBrowse link
G Slc6a5 solute carrier family 6 member 5 involved_in ISO
IBA
(PMID:16751771)
PMID:21873635
RGD PMID:16751771, PMID:21873635 RGD:13792537 NCBI chr 1:105,270,418...105,336,369
Ensembl chr 1:105,284,753...105,336,363
JBrowse link
glycine secretion, neurotransmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc6a9 solute carrier family 6 member 9 acts_upstream_of_or_within ISO (MGI:5523768|PMID:22988142) RGD PMID:22988142 MGI:5523768 NCBI chr 5:136,669,674...136,703,702
Ensembl chr 5:136,669,674...136,703,697
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    signaling 7458
      cell-cell signaling 1731
        synaptic signaling 916
          trans-synaptic signaling 889
            anterograde trans-synaptic signaling 880
              chemical synaptic transmission 880
                synaptic transmission, glycinergic 7
                  glycine secretion, neurotransmission + 1
                  negative regulation of synaptic transmission, glycinergic + 0
                  positive regulation of synaptic transmission, glycinergic + 0
                  regulation of synaptic transmission, glycinergic + 0
Path 2
Term Annotations click to browse term
  biological_process 19491
    cellular process 18343
      cell communication 7539
        cell-cell signaling 1731
          synaptic signaling 916
            trans-synaptic signaling 889
              anterograde trans-synaptic signaling 880
                chemical synaptic transmission 880
                  synaptic transmission, glycinergic 7
                    glycine secretion, neurotransmission + 1
                    negative regulation of synaptic transmission, glycinergic + 0
                    positive regulation of synaptic transmission, glycinergic + 0
                    regulation of synaptic transmission, glycinergic + 0
paths to the root