ONTOLOGY REPORT - ANNOTATIONS
Term: synaptic transmission, glycinergic
Accession: GO:0060012
browse the term
Definition: The vesicular release of glycine from a presynapse, across a chemical synapse, the subsequent activation of glycine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
G
Glra1
glycine receptor, alpha 1
acts_upstream_of_or_within involved_in
IDA ISO IEA
MGI:1856177|MGI:1856362 (PMID:16672662) (PMID:24801766) GO_REF:0000107
RGD Ensembl
PMID:16672662 PMID:24801766 PMID:15574743
GO_REF:0000107, RGD:1598572
NCBI chr10:39,625,853...39,727,897
Ensembl chr10:39,629,459...39,727,162
G
Glrb
glycine receptor, beta
involved_in acts_upstream_of_or_within
IDA IBA ISO IEA
GO_REF:0000033 MGI:1856363 (PMID:12809985), (PMID:1338094), (PMID:16672662) GO_REF:0000107
GO_Central RGD Ensembl
PMID:1338094 PMID:12809985 PMID:16672662 PMID:15574743
GO_REF:0000033 GO_REF:0000107, RGD:1598572
NCBI chr 2:166,134,616...166,207,498
Ensembl chr 2:166,134,626...166,207,489
G
Slc6a5
solute carrier family 6 member 5
involved_in
ISO IBA
(PMID:16751771) GO_REF:0000033
RGD GO_Central
PMID:16751771
GO_REF:0000033
NCBI chr 1:99,645,389...99,697,016
Ensembl chr 1:99,645,389...99,697,010
G
Slc6a9
solute carrier family 6 member 9
acts_upstream_of_or_within
ISO IEA
(PMID:22988142) GO_REF:0000107
RGD Ensembl
PMID:22988142
GO_REF:0000107
NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728
G
Slc7a10
solute carrier family 7 member 10
involved_in
IEA ISO
GO_REF:0000107 (PMID:25755256), (PMID:27759100)
Ensembl RGD
PMID:25755256 PMID:27759100
GO_REF:0000107
NCBI chr 1:87,829,084...87,845,073
Ensembl chr 1:87,829,175...87,845,071
G
Slc6a9
solute carrier family 6 member 9
involved_in
ISS IEA ISO
GO_REF:0000024 GO_REF:0000107 (PMID:14622582)
UniProt Ensembl RGD
PMID:14622582
GO_REF:0000024 GO_REF:0000107
NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all
Path 1
biological_process
20543
cellular process
19534
cell communication
7907
cell-cell signaling
1491
synaptic signaling
1011
trans-synaptic signaling
967
anterograde trans-synaptic signaling
959
chemical synaptic transmission
959
synaptic transmission, glycinergic
5
glycine secretion, neurotransmission +
1
negative regulation of synaptic transmission, glycinergic +
0
positive regulation of synaptic transmission, glycinergic +
1
regulation of synaptic transmission, glycinergic +
2
Path 2
biological_process
20543
biological regulation
13835
regulation of biological process
13398
signaling
7874
cell-cell signaling
1491
synaptic signaling
1011
trans-synaptic signaling
967
anterograde trans-synaptic signaling
959
chemical synaptic transmission
959
synaptic transmission, glycinergic
5
glycine secretion, neurotransmission +
1
negative regulation of synaptic transmission, glycinergic +
0
positive regulation of synaptic transmission, glycinergic +
1
regulation of synaptic transmission, glycinergic +
2