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ONTOLOGY REPORT - ANNOTATIONS

Term:Sertoli cell differentiation
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Accession:GO:0060008 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules.


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Sertoli cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsl cathepsin L IEP RGD PMID:15647457 RGD:1581112 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548 		JBrowse link
G Dmrt1 doublesex and mab-3 related transcription factor 1 involved_in
acts_upstream_of_or_within		 ISO (MGI:1926717|PMID:11040213)
MGI:2385911|MGI:2385912 (PMID:17540358)		 RGD PMID:11040213 PMID:17540358 MGI:1926717 NCBI chr 1:223,142,859...223,241,333
Ensembl chr 1:223,142,859...223,241,333 		JBrowse link
G Gata4 GATA binding protein 4 acts_upstream_of_or_within ISO MGI:3042214|MGI:3778685 (PMID:21172404) RGD PMID:21172404 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Inhba inhibin subunit beta A acts_upstream_of_or_within ISO (PMID:32274496) RGD PMID:32274496 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982 		JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1346833|MGI:2159321 (PMID:11564714), (PMID:15829514)		 Ensembl
RGD		 PMID:11564714 PMID:15829514 GO_REF:0000107 NCBI chr  X:50,756,886...50,761,014
Ensembl chr  X:50,756,886...50,761,011 		JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 acts_upstream_of_or_within ISO MGI:1352460 (PMID:15829514) RGD PMID:15829514 NCBI chr 3:22,464,786...22,486,328
Ensembl chr 3:22,465,502...22,486,328 		JBrowse link
G Safb2 scaffold attachment factor B2 acts_upstream_of_or_within ISO MGI:5695073 (PMID:26092125) RGD PMID:26092125 NCBI chr 9:1,395,852...1,417,010
Ensembl chr 9:1,387,107...1,417,038 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:2429649|MGI:3041881 (PMID:15056615)		 UniProt
RGD		 PMID:15056615 GO_REF:0000024 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Tcf21 transcription factor 21 involved_in IDA PMID:21637323 UniProt PMID:21637323 RGD:8553815 NCBI chr 1:22,701,353...22,704,212
Ensembl chr 1:22,701,353...22,704,202 		JBrowse link
G Wnt4 Wnt family member 4 acts_upstream_of_or_within ISO MGI:1857453 (PMID:15581876) RGD PMID:15581876 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
establishment of Sertoli cell barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arid4a AT-rich interaction domain 4A acts_upstream_of_or_within ISO MGI:2137512 (PMID:23487765) RGD PMID:23487765 NCBI chr 6:89,522,459...89,593,868
Ensembl chr 6:89,522,442...89,593,510 		JBrowse link
G Arid4b AT-rich interaction domain 4B involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2444354 (PMID:23487765)		 Ensembl
RGD		 PMID:23487765 GO_REF:0000107 NCBI chr17:51,138,419...51,262,894
Ensembl chr17:51,138,535...51,262,906 		JBrowse link
G Flna filamin A IMP RGD PMID:22872576 RGD:7207404 NCBI chr  X:152,007,758...152,034,266
Ensembl chr  X:152,007,758...152,031,052 		JBrowse link
G Icam1 intercellular adhesion molecule 1 IDA RGD PMID:22976294 RGD:8547721 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Itgb1 integrin subunit beta 1 IEP RGD PMID:22872576 RGD:7207404 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Rab13 RAB13, member RAS oncogene family involved_in IMP PMID:23419316 UniProt PMID:23419316 RGD:8554106 NCBI chr 2:175,674,894...175,680,043
Ensembl chr 2:175,675,005...175,680,036 		JBrowse link
negative regulation of establishment of Sertoli cell barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1a interleukin 1 alpha IDA RGD PMID:18057314 RGD:10046056 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
positive regulation of establishment of Sertoli cell barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A IMP RGD PMID:28880272 RGD:13703098 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Cftr CF transmembrane conductance regulator IMP RGD PMID:22777528 RGD:11567213 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756 		JBrowse link
G Gja1 gap junction protein, alpha 1 IMP RGD PMID:26678449 RGD:11532443 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
Sertoli cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrm1 ADRM1 26S proteasome ubiquitin receptor involved_in ISO (MGI:4849324|PMID:21048919) RGD PMID:21048919 MGI:4849324 NCBI chr 3:167,265,435...167,270,197
Ensembl chr 3:167,265,296...167,270,195 		JBrowse link
G Akap9 A-kinase anchoring protein 9 acts_upstream_of_or_within ISO MGI:3050560 (PMID:23608191) RGD PMID:23608191 NCBI chr 4:30,056,738...30,192,716
Ensembl chr 4:30,056,738...30,192,606 		JBrowse link
G Atrx ATRX, chromatin remodeler involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3528480 (PMID:21427128)		 Ensembl
RGD		 PMID:21427128 GO_REF:0000107 NCBI chr  X:70,850,981...70,997,330
Ensembl chr  X:70,850,981...70,997,330 		JBrowse link
G Cst3 cystatin C IEP RGD PMID:9432134 RGD:2306517 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822 		JBrowse link
G Dmrt1 doublesex and mab-3 related transcription factor 1 acts_upstream_of_or_within ISO MGI:2385911 (PMID:21775990) RGD PMID:21775990 NCBI chr 1:223,142,859...223,241,333
Ensembl chr 1:223,142,859...223,241,333 		JBrowse link
G Esr1 estrogen receptor 1 IEP RGD PMID:24056172 RGD:7364870 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 IEP RGD PMID:24056172 RGD:7364870 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Fer FER tyrosine kinase IEP RGD PMID:12700184 RGD:2291909 NCBI chr 9:103,520,452...103,827,364
Ensembl chr 9:103,520,493...103,821,451 		JBrowse link
G Fndc3a fibronectin type III domain containing 3a acts_upstream_of_or_within ISO MGI:1857062 (PMID:1759682), (PMID:2164218) RGD PMID:1759682 PMID:2164218 NCBI chr15:47,689,909...47,867,354
Ensembl chr15:47,689,919...47,866,784 		JBrowse link
G Fshr follicle stimulating hormone receptor acts_upstream_of_or_within ISO MGI:2384087 (PMID:14998910) RGD PMID:14998910 NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785 		JBrowse link
G Gata1 GATA binding protein 1 IEP RGD PMID:9089398 RGD:2317794 NCBI chr  X:14,529,706...14,537,530
Ensembl chr  X:14,529,702...14,537,530 		JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2385822 (PMID:16484321)		 Ensembl
RGD		 PMID:16484321 GO_REF:0000107 NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952 		JBrowse link
G Map7 microtubule-associated protein 7 acts_upstream_of_or_within ISO MGI:2148221 (PMID:10837026) RGD PMID:10837026 NCBI chr 1:14,910,433...15,037,574
Ensembl chr 1:14,910,551...15,037,574 		JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 IMP RGD PMID:18660385 RGD:5684384 NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770 		JBrowse link
G Nup210l nucleoporin 210-like acts_upstream_of_or_within ISO MGI:3045544 (PMID:20034429) RGD PMID:20034429 NCBI chr 2:175,545,999...175,665,332
Ensembl chr 2:175,547,988...175,665,332 		JBrowse link
G Sdc1 syndecan 1 IEP RGD PMID:12453641 RGD:1643137 NCBI chr 6:31,562,799...31,585,267
Ensembl chr 6:31,562,739...31,585,264 		JBrowse link
G Sox3 SRY-box transcription factor 3 involved_in ISO (MGI:5142371|PMID:11875113) RGD PMID:11875113 MGI:5142371 NCBI chr  X:139,308,608...139,310,687
Ensembl chr  X:139,309,329...139,310,678 		JBrowse link
G Sox8 SRY-box transcription factor 8 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:98371 (PMID:19124014)
(MGI:5142371|PMID:11875113)		 UniProt
RGD		 PMID:11875113 PMID:19124014 GO_REF:0000024 MGI:5142371 NCBI chr10:14,584,829...14,589,818
Ensembl chr10:14,584,829...14,589,818 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within		 IEP
ISO		 PMID:11875113
MGI:98370 (PMID:19124014)		 RGD PMID:19124014 PMID:11875113 RGD:1299273 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Wt1 WT1 transcription factor acts_upstream_of_or_within ISO (PMID:16418481) RGD PMID:16418481 NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643 		JBrowse link
Sertoli cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rara retinoic acid receptor, alpha involved_in ISO (MGI:5284770|PMID:17905941) RGD PMID:17905941 MGI:5284770 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20115
    reproductive process 1919
      developmental process involved in reproduction 1229
        Sertoli cell differentiation 39
          Sertoli cell development + 30
          Sertoli cell fate commitment 1
Path 2
Term Annotations click to browse term
  biological_process 20115
    developmental process 7008
      anatomical structure development 6530
        multicellular organism development 5268
          system development 4550
            reproductive system development 436
              reproductive structure development 431
                gonad development 339
                  male gonad development 207
                    Sertoli cell differentiation 39
                      Sertoli cell development + 30
                      Sertoli cell fate commitment 1
paths to the root