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ONTOLOGY REPORT - ANNOTATIONS


Term:response to hyperoxia
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Accession:GO:0055093 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension.
Synonyms:exact_synonym: response to hyperoxic stress;   response to increased oxygen tension


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response to hyperoxia term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor IEP RGD PMID:17343756 RGD:1625339 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member IEP RGD PMID:16782756 RGD:2306340 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Alox5 arachidonate 5-lipoxygenase IEP RGD PMID:12490039 RGD:4890420 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Bdnf brain-derived neurotrophic factor IEP RGD PMID:15821016 RGD:4891113 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Bnip3 BCL2 interacting protein 3 IEP RGD PMID:20157446 RGD:5128796 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G Cat catalase IEP RGD PMID:19895324 RGD:5130747 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 IEP RGD PMID:21404274 RGD:5130888
G Cdk4 cyclin-dependent kinase 4 IEP RGD PMID:18082050 RGD:2289663 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A IEP RGD PMID:18082050 RGD:2289663 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Col1a1 collagen type I alpha 1 chain IEP RGD PMID:11918316 RGD:8552772 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 IEP RGD PMID:16497785 RGD:2306657 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Eln elastin IEP RGD PMID:9609733 RGD:9585726 NCBI chr12:24,978,478...25,021,864
Ensembl chr12:24,978,483...25,021,863
JBrowse link
G Epo erythropoietin IEP RGD PMID:19768476 RGD:2313637 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Hdac1 histone deacetylase 1 IEP RGD PMID:21905265 RGD:9590253 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Hdac2 histone deacetylase 2 IEP RGD PMID:21905265 RGD:9590253 NCBI chr20:43,084,870...43,108,198
Ensembl chr20:43,084,870...43,108,198
JBrowse link
G Il18 interleukin 18 IEP RGD PMID:19672068 RGD:4889402 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 IEP RGD PMID:16735674 RGD:8693740 NCBI chr 4:159,077,195...159,079,003
Ensembl chr 4:159,077,195...159,079,003
JBrowse link
G Mmp2 matrix metallopeptidase 2 IEP RGD PMID:19099751 RGD:5129684 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 IEP RGD PMID:19099751 RGD:5129684 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mt-atp6 mitochondrially encoded ATP synthase membrane subunit 6 IEP RGD PMID:18481000 RGD:2298955 NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599
JBrowse link
G Mt-atp8 mitochondrially encoded ATP synthase membrane subunit 8 IEP RGD PMID:18481000 RGD:2298955 NCBI chr MT:7,758...7,961
Ensembl chr MT:7,758...7,961
JBrowse link
G Mt-cyb mitochondrially encoded cytochrome b IEP RGD PMID:18481000 RGD:2298955 NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278
JBrowse link
G Ncf2 neutrophil cytosolic factor 2 IEP RGD PMID:19337906 RGD:2314428 NCBI chr13:70,226,441...70,259,019
Ensembl chr13:70,226,647...70,257,576
JBrowse link
G Nos3 nitric oxide synthase 3 IEP RGD PMID:17937862 RGD:2292125 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha IEP RGD PMID:15722379 RGD:1580851 NCBI chr14:35,527,926...35,581,130
Ensembl chr14:35,527,927...35,581,031
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta IEP RGD PMID:15722379 RGD:1580851 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 IEP RGD PMID:19411306 RGD:9999157 NCBI chr 3:113,376,983...113,400,707
Ensembl chr 3:113,376,983...113,400,707
JBrowse link
G Pdpn podoplanin IEP
IBA
PMID:21873635 RGD
GO_Central
PMID:12922978, PMID:21873635 RGD:1302251, RGD:13792537 NCBI chr 5:161,947,137...161,981,441
Ensembl chr 5:161,947,137...161,981,441
JBrowse link
G Plau plasminogen activator, urokinase IEP RGD PMID:19099788 RGD:4143526 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Plcd1 phospholipase C, delta 1 IEP RGD PMID:12850505 RGD:1299008 NCBI chr 8:127,753,514...127,782,070
Ensembl chr 8:127,753,539...127,782,070
JBrowse link
G Polb DNA polymerase beta IEP RGD PMID:8786668 RGD:8694108 NCBI chr16:74,237,001...74,260,272
Ensembl chr16:74,237,001...74,260,271
JBrowse link
G Polg DNA polymerase gamma, catalytic subunit IEP RGD PMID:8786668 RGD:8694108 NCBI chr 1:141,172,117...141,188,893
Ensembl chr 1:141,172,531...141,188,031
JBrowse link
G Sell selectin L IEP RGD PMID:12730074 RGD:5686287 NCBI chr13:82,369,820...82,387,774
Ensembl chr13:82,369,493...82,387,631
JBrowse link
G Serpine1 serpin family E member 1 IEP RGD PMID:19099788 RGD:4143526 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Sftpa1 surfactant protein A1 IEP RGD PMID:11472975 RGD:4143429 NCBI chr16:18,716,019...18,719,404
Ensembl chr16:18,716,019...18,719,403
JBrowse link
G Sftpb surfactant protein B IEP RGD PMID:11472975 RGD:4143429 NCBI chr 4:100,166,855...100,175,941
Ensembl chr 4:100,166,863...100,175,938
JBrowse link
G Sftpc surfactant protein C IEP RGD PMID:11472975 RGD:4143429 NCBI chr15:52,211,538...52,214,480
Ensembl chr15:52,211,544...52,214,616
JBrowse link
G Sftpd surfactant protein D IEP RGD PMID:11472975 RGD:4143429 NCBI chr16:18,753,535...18,766,100
Ensembl chr16:18,745,458...18,766,174
JBrowse link
G Sod2 superoxide dismutase 2 ISO MGI:MGI:1857344 (MGI:MGI:2159522|PMID:11796207) RGD PMID:11796207 MGI:MGI:2159522 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Tp53 tumor protein p53 IEP RGD PMID:18337831 RGD:2290551 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Txnrd1 thioredoxin reductase 1 IEP RGD PMID:20493230 RGD:5133717 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Txnrd2 thioredoxin reductase 2 IEP RGD PMID:20493230 RGD:5133717 NCBI chr11:86,667,994...86,716,063
Ensembl chr11:86,667,997...86,716,254
JBrowse link
G Wnt5a Wnt family member 5A IEP RGD PMID:17911382 RGD:2304247 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
cellular response to hyperoxia term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg7 autophagy related 7 ISO
ISS
(PMID:20543840)
GO_REF:0000024
RGD
UniProt
PMID:20543840 GO_REF:0000024 NCBI chr 4:146,570,113...146,777,093
Ensembl chr 4:146,598,413...146,777,124
JBrowse link
G Cav1 caveolin 1 IEA
ISO
GO_REF:0000107
(PMID:21382479)
Ensembl
RGD
PMID:21382479 GO_REF:0000107 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta IEP RGD PMID:23039253 RGD:9589076 NCBI chr 3:149,131,541...149,170,061
Ensembl chr 3:149,131,785...149,208,786
JBrowse link
G Egr1 early growth response 1 IEP RGD PMID:15734424 RGD:5131935 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Fas Fas cell surface death receptor ISO (PMID:21382479) RGD PMID:21382479 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Foxo1 forkhead box O1 ISO
ISS
(PMID:20543840)
GO_REF:0000024
RGD
UniProt
PMID:20543840 GO_REF:0000024 NCBI chr 2:141,451,234...141,527,016
Ensembl chr 2:141,451,234...141,527,016
JBrowse link
G Nox1 NADPH oxidase 1 ISO
IEA
MGI:MGI:3616995 (MGI:MGI:4881403|PMID:19661248)
GO_REF:0000107
RGD
Ensembl
PMID:19661248 GO_REF:0000107, MGI:MGI:4881403 NCBI chr  X:104,909,328...104,932,508
Ensembl chr  X:104,909,326...104,932,508
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma IEP RGD PMID:22444276 RGD:8553189 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Txn1 thioredoxin 1 IEP RGD PMID:21505996 RGD:5133704 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
JBrowse link
G Txnrd1 thioredoxin reductase 1 IEP RGD PMID:21505996 RGD:5133704 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    response to stimulus 10583
      response to stress 4061
        response to hyperoxia 52
          cellular response to hyperoxia 10
Path 2
Term Annotations click to browse term
  biological_process 20027
    response to stimulus 10583
      response to abiotic stimulus 1511
        response to oxygen levels 535
          response to increased oxygen levels 59
            response to hyperoxia 52
              cellular response to hyperoxia 10
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.